Accutane is so hardcore. It's amazing how many side effects it can cause and how varied they can be. For sure you want to make sure you tell your doc about what you're experiencing and rule out that it's something you need to be concerned about. So I'd say that's first.

When I was on Accutane my joints hurt really badly. I didn't work out when I was on it, but I could imagine how hard it would have been for me to even try. My joints have never been quite the same since, so hopefully what you're experiencing will be temporary. But overall, what I would have to say to you is to be careful, stay your own advocate, and remember that you have the rest of your life to deal with and you don't want lasting side effects. Stay on top of this.

Posted by: @Axxa29

I am currently on my 2nd accutane treatment. First time was 30mg every day and it almost cured the acne. I started the 2nd treatment after 2 years due to my oily skin + some pimples here and there.

The biggest problem right now is, that I am extremly tired even on 10mg every day which I had not on my first treament.

Even with coffein pills etc. I am really tired and can't even finish my normal gym session.

Does any one have the same problem or know any supplements which can fix that?

I am just curious why i did not have these side effects on my first treatment on higher dosage.

I took two doses. First was 40mg, second was 20mg, same time period a 2 year period. Same effects, nearly cured, a little residual, 2nd dose did the trick more or less. I can't remember any side effects at all really, but you know they do make you feel a little different in general, like I felt more hyped or anxious if I can remember. It's a strong drug, I'm sure everyone reacts differently and age also plays a role in how you react.

Not sure I'd try to "fix it" if it's from the accutane you just have to complete the course. I wouldn't be trying to take too many drugs alongside accutane. It's strong enough.