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I've never tried it because I heard it can take way longers to see results this way, but I haven't read anywhere it can break you out more or anything.
I usually moisturise 15-30 mins after I put it on.
I know what you mean about the really pale face and heavy eyes. My eyes have only stopped being so heavy in the last week (I am pretty much at the 3 month mark)
wow you get a lot of bad information on this website. Your skin absorbs medication to a greater extent when it is damp then when it is dry this is why the instructions will always say to use after your skin dries (I would wait at least 30 minutes) to avoid excessive irritation. Using moisturizer before or after using differin would be fine.