The longer you use antibiotics like minocycline and clindamycin, the less effective they will become. This is because bacterial resistance will develop.

It is a big deal if you are consistently missing retinoid applications. Make sure it is being applied every night. I find I can miss one night every so often but any more than that and things become problematic.

0.025% tretinoin cream (Retin-A Micro?) is pretty mild. This is why you did not experience much irritation when first trying it. I would switch to gel (you will get better absorption) and move up to 0.04% at the very least. If you don't get improvement within a month immediately move up to a 0.1% concentration, and perhaps also switch to tazarotene.

A lot of the time variations in the state of your skin are due to variations in your diet. Make sure your monitor your intake of animal milk products and high-glycemic load foods and see if there is any correlation between such intake and the state of your skin.