Hello,

So, here is my little story. I'm 27 guy, oily skin profile, acne prone since 15. Past of spot picker due to nerves etc... 2 accutane long courses which cleared me totally without a lot of side effects. Then did more than 1,5 years of DKR which worked fine but I was pissed of applyling so much topicals and of bleaching effects etc...

So I went to my derm who, 3 months ago, put me on accutane low dose. He said it would be miracle cure, and I just needed to wash my skin with water.

My skin cleared very fast and was not oily anymore.

First month, I was on 5 mg a day, now I am on 2 * 20mg a week.

However, my gf and I noticed some serious side effects on mood. I must first say, I had a depressive episode when 19, which was supposed to be a standard post-teenage depressive phase and went away. I am a quite nervous person with a tendancy to be nervous.

The last 3 months, I started to have more anxious feelings for no apparent reasons (no external stressors) : my relationship is really good with gf, work is OK, no money issues, lots of plans.

Then I noticed, when watching movies, I would be emotional, which is totally new for me. I sometimes felt like crying. The fact is that I had not cried for the last 5 years or something and the last time was due to a very hard breakup with an ex gf.

Then, the last weeks, it has become worse. I started to feel sad when waking up, then feeling like jolted, angry, the day, like it was a reaction, then the evening I would become sad again. Sometimes, when going to sleep, I would feel like crying for no apparent reason or for stupid reasons.

Overall, my stress resistance has crushed at work too. I feel like... how to say that... weak. I really feel weak against normal life events or stressors. I am unable to focus for a long time and I don't take a lot of pleasures from activities I love (sport, video games etc)

I ve been missing sport a lot because I have a lot of pain in my shoulders after playing ball.

I tried to check the reasons of this. I do not take any medication. I stopped to smoke weed (which had quite similar effects during "hangovers") years ago. I don't even take acetominophen or anything.

The only "culprit" seems to be Accutane.

Do you think it can be linked ?

Anyone experienced the same things ?

Thanks