My theory is that accutane gets trapped in different parts of the body for different people, and that proper lymph flow and bile flow are critical for complete removal from the body.
accutane oxidizes cholesterol. If its stuck in the body youre going to struggle to maintain adequate cholesterol levels, which explains my constant cravings for saturated fat.
cholesterol is the precursor to lymph fluid and bile. Water is also a precursor to bile. Accutane causes the body to not absorb and store water. I believe accutane also causes an overactive immune system.
so far Im liking the combo of beta glucan, beef brain and vitamin c gummies. I also added some coconut water yesterday. My body seems to crave the stuff. Coconut water is deeply hydrating.
had some massive loose stools last night, which I suspect is a detox reaction. I feel lighter and just overall a little better today. Definitely not healed but feels like Im going in the right direction.
Calcified seems to be the only one who can tolerate high levels of retinol. Usually its the other way for everyone else. Could be accutane is trapped in a specific part of his body that allows him so much retinol intake.

Yeah it might be trapped or the receptors are "retinol resistant"

Regarding cholesterol my levels went dangerously high when I started mega doses of retinol, but they are now normal.

Ive dropped the beta glucan in favor of increasing whole grain food intake. Multigrain squares cereal, oatmeal raisin cookies, sun chips non original whole grain chips, whole grain fig newtons, etc. sun chips uses gmo for their original flavor, but not for the other flavors. Still doing the beef brain pills daily, along with vitamin c gummies.
accutane is a fat soluble poison, and the brain is the fattiest organ in the human body. It would make sense that accutane would accumulate in large quantities in the brain, and in some cases remain trapped for years after ceasing use. I believe regular daily intake of beef brain pills can slowly over time help to push it out of the body once and for all.

Keywords:acne; ferritin; isotretinoin; urea; uric acid.

Posted by: @cardoor

New here and to be honest I always thought the only side effect from accutane was dry skin (which I was totally fine with). Im currently dating a girl that I struggle keeping erections with. This is an issue Ive had since I was 18. I always thought it was an anxiety thing because when Im by myself I dont have the issue as much. Now I think its because I know the best way to pleasure myself and it takes lots of control and the exact correct movements. One day Im talking to my girlfriend about how I had horrible acne 16 years ago and I took accutane. She asked me what the long term effects were and I just said dry skin.. then we looked it up. And 3 serious side effects stuck out to me. Loss of libido (I still have one but its not nearly as strong as other men), numbness in the penis (not completely numb, I enjoy sex and it does feel good but I always had the feeling that I didnt enjoy it as much as others) and the loss of erection.

All these symptoms started around the time I started the drug. I was visiting my old hometown when I was 18 staying in a hotel. I hadnt eaten a lot that weekend (no Uber and I was in the middle of nowhere) and when my ex came to visit I also drank that night. I got ED. Not even loss of erection. I couldnt even get one. I freaked out, she was disappointed and I thought that was the reason for my anxiety for the next 10+ years. Luckily for me ED medication does help. (I cant finish on them but at least they help) I had so many horribly embarrassing moments with women throughout my life and I never once thought the root cause could be accutane. Doctors told me to exercise and eat better blah blah blah. I feel slightly better but also sad that there could possibly be no permanent fix for my issue.

A lot of it has to what Accutane did to our brain (HPA axis) and hormonal system. Negative effect on testicles. It also damages liver and digestive system which matters. There are still new studies coming out on specifics of Accutane's mechanism of action. A lot of unknown. Only, only if they can better understand it and develop a drug or plan to restore and repair. There are got to be some way. Neurogenesis and gene theray are promising but the progress has been slow.

I mean the brain is malleable. Some degree of repairs should be possible. I bet you lost spontaneous erections, morning woods and was only able to get it through physical stimulation. Even that doesn't help much. It seems the brain is not able to signal the penis or the penis is not responsive to what the brain tries to send. Again, hormones and neurological problems.

The pharmaceutical industry and medical community really owes us a solution considering the hundreds and thousands of lives they have destroyed and taken. It will save lives. People who suffer from hypogonadism or Sjogren's syndrome etc will benefit from this. It could initiate a revolution in endocrinology. I really think people should get connected and act. Given the amount of damage it has done to people. We have remained silent for long and has done too little.

In case your need it: [Edited link out]

Not sure how wed convince anyone??

After 25 years, not one test is conclusive of anything, so that would work against us

And, for every person whos had adverse effects, there would be 500 people who had no problem at all on Accutane

What do you do??

Ive just gone gluten free, and it seems to be a step in the right direction. Below is my current program. Will keep the board posted on how it goes.

Raw beef x1 of each daily

Brain Intestines Non defatted liver

Diet

Gluten free omnivore

Milk

Lactose free 2%

Gluten free entrees

AmysAnniesLean cuisineHealthy choiceDinty Moore beef stew

Gluten free non gmo whole grains

Quaker rice chipsOatmeal raisin cookiesWalmart granola cerealMinute brown rice bowls

Primary fruits

DatesRaisinsCanned cherries

Primary juice

Carrot

Primary meats

Beef franksBeef pattiesGluten free chicken nuggetsFully cooked chicken sausage

Acceptable candy

Milk chocolate covered raisins

Acceptable soda

Ginger ale 7.5 oz

Gluten free fast foods

Chik fil aTaco bellFirehouse subsJersey mikes subs

Avoid

Soy Pork Eggs Stevia Gluten Alcohol Lactose Peanuts Caffeine Tobacco Seafood Tree nuts Fodmaps Deodorant Raw veggies Non ginger soda Artificial sweeteners

Dr Rons and life giving store both make excellent beef brain products. The beef intestines is ancestral supplements. And lots of decent suppliers of whole beef liver pills are out there.
ancestral supplements makes a brain and liver combo, but my body doesnt seem to like it as much as other brands of brain. Your body may differ.
These products are expensive, but doing just one pill daily of each and the price actually isnt so bad. I dont think youd want to do more than one pill of each daily anyway.

So for those suffering from erectile dysfunction, HCG injections can really improve libido although it requires a prescription and can be hard to get. Daily HCG injections can improve testosterone levels from around 300pcg/dl to around 500-600pcg/dl (near normal levels).

I just dont think gluten free or lactose free makes a difference for us. As for beef organs and tissues, Im finding I do best with ancestral living bone and codeage beef spleen. Other than calcium, beef bone is rich in glucuronic acid, which is what attaches to accutane in phase two detox. Beef spleen is the worlds richest source of heme iron, which is needed for cytochrome p450, aka phase one detox. I also just started consuming pork rinds almost daily. Like heals like. Accutane destroyed our skin, so Im consuming the skin of healthy swine to restore my own post accutane skin. I should mention that pork rinds are loaded with glycine and arginine. Glycine is huge for 5 alpha reductase and arginine is huge for circulation.
I believe the drug is trapped in the body and the body simply needs the tools to get rid of it. Will see how this combo goes.

Posted by: @thomas76

I just dont think gluten free or lactose free makes a difference for us. As for beef organs and tissues, Im finding I do best with ancestral living bone and codeage beef spleen. Other than calcium, beef bone is rich in glucuronic acid, which is what attaches to accutane in phase two detox. Beef spleen is the worlds richest source of heme iron, which is needed for cytochrome p450, aka phase one detox. I also just started consuming pork rinds almost daily. Like heals like. Accutane destroyed our skin, so Im consuming the skin of healthy swine to restore my own post accutane skin. I should mention that pork rinds are loaded with glycine and arginine. Glycine is huge for 5 alpha reductase and arginine is huge for circulation.
I believe the drug is trapped in the body and the body simply needs the tools to get rid of it. Will see how this combo goes.

Unfortunately when it comes to testosterone, there is likely apoptosis in the leydig cells so there is no real possibility to recover. We might be chasing something of a fantasy when it comes to repairing the long term damage. Once the Leydig cells have been destroyed, there is no going back, they do not replicate during adulthood. I have heard that in extreme states of starvation that a certain degree of Stem Cell replication is possible but in order to get anything substantial, we are talking 20 days or more of 0 calories. I am very dissipointed that there isn't more research into the subject, we don't know the root cause of post retinoid syndrome and there is very scarce research into the subject. The average doctor does not even recognize post retinoid syndrome to exist. The reason that I say that the Isotretinoin is not in the body still is that we haven't heard of anyone actually recovering from Isotretinoin. The damage is likely happening to the stem cells and once they are eliminated, they are gone for life. I went 13 days without eating or consuming any calories, and my chronic joint pain went away permanently and there was maybe a 10% improvement in libido. The deepest epigenetic cleanse happens while fasting, not by consuming anything. I am wondering if anyone has tried consulting Kevin Pezzi, he has an IQ of around 160 and is very accomplished in medicine and also once they took Isotretinoin. I payed $200 for an answer from him about 5 years ago and he was able to tell me that it likely had to do with apoptosis in the Leydig cells.(Leydig cells are a type of Stem Cell that produces testosterone) For my overall dryness of the mouth as wells as the eyes, there may be apoptosis of critical stem cells that create the original moisture. I would take my acne back any day to have my symptoms reversed, however I think it is important to accept that this is the way that we will be for the rest of our lives, there is no going back since we haven't heard of anyone making a recovery.

I strongly suspect accutane behaves in a manner similar to cancer, able to travel back and forth to different parts of the body, depending on which body part(s) are most hospitable for it. The main body parts I believe it travels to include the skin, brain, prostate, and gut. Well what if you can simultaneously create inhospitable conditions for it in all four of these areas at the same time, then what? Then it has no option other than the toilet, which is where we all want it to go until its completely gone for good.
for the first time ever Im trying a combo of beef brain, beef prostate, beef intestines, and pork rinds tonight, and will see how it goes.

hermie09

with regard to Leydig cell death, how do you know about this in relation to isotretinoin? Are there reports

I know its been mentioned on here before but not backed up by anything, just an opinion

*This is a private message i sent, posting also here in case someone can help*

A short recap for you: i took accutane 2 years ago, 3 months x 10 mg. Since i stopped the main side were: a little bit less libido, that now seems to be returned to normality, acne completely disapperad wouldnt consider that a side but it is absurd how a low dose like that can change something permantently like acne, and the main side is Hairloss as i told you, i am still losing hairs in a diffuse way and im remained with 30% of density.

Now i am also noticing since many months that i have huge digestive problems, it might be something related to gut, i seem to have hard times trying to digest fat foods, milk, carbos and many other, i produce a lot of mucus in my throat and rarely i also see blood in my stools.

I already took a gut microbiome test in these days and waiting for the result in a month, but i am pretty sure that i either have an inflammation going on somewhere in the digestive system, or i have some intolerance.

My plan is to:
1) Check my microbiome results, fix that if there is anything messed up.
2) Start a lowfod map and try to see what gives problems.
4) Water fast for somewhere from 7 to 13 days, depends on how far i can go.
5) Take a food intolerance test
4) Get a scalp biopsy for the hairloss as i think i might have lichen planoplanaris.

I think that my gut is somehow messing up my hairs other than my whole mental mood, confusion, sleep problems. I wanted to ask you about an opinion about my plan and ask if you have anything to suggest and if you experienced something like this personally, in general do you have any solution or tip to fix an inflamed gut?

Hair loss and Ibs are two of my issues as well. Im not a big fan of water only fasting or any type of fasting other than daily fasting, which means going anywhere from 12 to 23 hours without food every day, but still eating a healthy amount of calories daily. This is the very best kind of fasting.
I believe the drug is trapped in the body in multiple areas, including your scalp and your gut. Once you eliminate the drug from your body the hair loss and Ibs issues will resolve.
Beef organs and tissues are incredibly healthy but I dont think they are needed for accutane recovery. The two things I currently believe are needed for recovery are broccoli sprout capsules and seaweed capsules daily. Currently Im doing Earthborn elements Irish Sea moss and Earthborn elements broccoli sprouts. These are likely the most potent detoxifiers on the planet. More effective than spirulina, chlorella, or garlic. Crucifers like broccoli sprout pills do three key things. Activate nrf2, activate cytochrome p450, and activate glucuronidation. These three things are huge for accutane recovery.
Seaweed is like a mop mopping up the mess in the gut once broccoli sprouts have pulled accutane out of the cell nucleus and into circulation. Will keep the board posted on how this combo goes.

Regarding IBS/SIBO/Dysbiosis issues induced by Isotretinoin...it seems that the matter is much more serious than it might seem at first.

I recommend to all of you the following study: Severe Acne in Female Patients Treated with Isotretinoin is Associated with Dysbiosis and its Consequences

Isotretinoin is associated with dysbiosis, malabsorption (with visceral fat decrease) and signs of dysimmunity. Symptoms develop more than 20 years after the intake of the medication taken at usual range and duration. A facilitating role of Propionibacterium acnes cannot be excluded. Isotretinoin is known to impair stem cells renewal and TLR2 expression in the mucosa of the small gut. These pharmacological effects may induce the progressive atrophy of the jejunal mucosa and its long-lasting consequences. No therapy is available yet. Patients, prescribers and authorities should be aware of this adverse event which incidence is high (2.6% of outward gastroenterological consultations) especially when multi-annual surveillance for several years are expected.

I contacted the author of the study who claimed that the effects of Isotretinoin in the male population will be the same.

He also mentioned that Isotretinoin-induced malabsorption/digestive issues are related to the apoptosis of stem cells and that the use of antibiotics normally used to treat SIBO/IBS is useless.

So I guess it's really "game over" (at least with the current state of knowledge) for people who suffer from gastrointestinal issues after taking Isotretinoin.

As a consolation, I will only add that he also mentioned that you can at least "try" to repair the small intestine mucosa with a ketogenic diet and added that you should avoid nickel-rich foods that are very inflammatory on the thin mucosa.

In addition, let me just mention that from what I have been able to find, it seems that in the case of damaged/thinned mucosa of the small intestine (I assume that this is the case in 99% of people suffering from "IBS" after taking Isotretinoin) it would be worth trying L-arginine & Zinc L-carnosine & n-3 fatty acids (see studies below):

https://pubmed.ncbi.nlm.nih.gov/22545735/ L-arginine

https://pubmed.ncbi.nlm.nih.gov/22456439/ n-3 fatty acids

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856764/ Zinc carnosine

Posted by: @truejustice

hermie09

 

with regard to Leydig cell death, how do you know about this in relation to isotretinoin? Are there reports

I know its been mentioned on here before but not backed up by anything, just an opinion

 

There are no direct reports of this. The sebaceous glands are unique to human beings. Testosterone makes the pores larger and with larger pores comes acne. The mechanism of action for this drug might be as simple of apoptosis in the Leydig cells leading to lower testosterone levels leading to to smaller pores, leading to less acne. The sebaceous gland(the human skin pores) are unique to human beings. With too small of glands there is little sweat produced and dry skin and with too large of glands comes acne. Testosterone levels in human beings are higher than in chimpanzees which do not have sebaceous glands. The exact mechanism for how isotretinoin clears up acne is not fully understood at least in publicly displayed scientific data but that is my hypothesis. It might be that scientists understand this and have repressed the data from being understood by the public because they don't want the general public to know since it would lower their sales if not get isotretinoin banned as a pharmaceutical. I was told by Kevin Pezzi, who mentions isotretinoin in his Book "The Science of Sex." that the isotretinoin likely involves permanent epigenetic changes and apoptosis in the Leydig cells. It might be that 3 million people have taken this drug and for nearly every single one of them, they do not report side effects. Isotretinoin(Accutane, 13- cis retinoic acid) is now being prescribed as a form of hormone therapy for males that are looking to go through a sex change because it permanently lowers testosterone levels. This is very frightening. We might all be half way to being hormonally transgender with no way back and this is a form of status quo that exists because of big pharma. For purposes of morale, I highly recommend HCG to up testosterone levels from about 200-350pcg/dl to 500pcg/dl however this is just a temporary bandade that fixes testosterone levels in the short run. I think we need to try to get the funding through a law suite to fund scientific research into the subject to see what the biological mechanism of isotretinoin is before blindly trying to cure isotretinoin without knowing what has been altered and why. I am thinking some where around 5 million dollars would have to be raised to get proper funding for the scientific research. With 3 million people that have taken the drug, there needs to be a raising of awareness to get that type of funding. I am just wondering, has anyone on here tried experimenting with vitamin C? I have heard that it can have a significant impact on libido. Apparently LH(luteinizing hormone) stimulates the leading cells so if testosterone levels are low with high levels of luteinizing hormone, then it has to do with dysfunctional leading cells. Does anyone have lab results with luteinizing hormone?

Posted by: @truejustice

hermie09

 

with regard to Leydig cell death, how do you know about this in relation to isotretinoin? Are there reports

I know its been mentioned on here before but not backed up by anything, just an opinion

 

Animal studies have demonstrated impaired spermatogenesis. In adult male gerbils, isotretinoin
induced almost complete cessation of spermatogenesis and produced alterations in the cytoplasm of
Leydig cells (Sadek & Abdul-Mohsen, 1999). In the adult lizard administration of ATRA impaired
spermatogenesis and enhanced testicular germ cell apoptosis (Comitato, Esposito, Cerbo, Angelini, &
Varriale, 2006). These studies point to an increased risk of isotretinoin-induced germ cell apoptosis in
these retinoid-susceptible species but the implication for humans is unknown.

Independent report
REPORT OF THE COMMISSION ON HUMAN
MEDICINES ISOTRETINOIN EXPERT WORKING
GROUP
26 April 2023

Thanks for the last few posts on Leydig cells, very good responses actually - quite scary to hear this, just how many men are suffering Id be very curious to know.

And as we know, the joy doesnt just stop there, I suspect I have gut dysbiosis although in mentioning this yesterday to my kinesiologist he said thats just a word, most people he works on have something wrong with their gut, reflux & heartburn for me and probably malabsorption of anything else you can think of.

Aside from this, my B6 in particular is not working as it should, this apparently is tied up with too much estrogen and poor iron absorption. Worked on T3,T4 thyroid to correct and rebalance, T3 wouldnt turn off, probably take a few sessions to do all this.

Have no idea if any of this is from isotretinoin or not.as we know, nothing is ever conclusive after taking this shit poison 20 plus years ago

Good times indeed

I just read an article stating that the consumption of omega 3's can drastically improve testosterone. So there is no way back for the leydig cells but with exercise, water fasting, omega 3's, and hcg you can return to near normal testosterone levels perhaps. For water fasting, I am talking about 15 days or more. I am personally thinking about doing 40 days.

Each to their own I guess

theres no way Im injecting HCG

Where does that end?? Gotta do it for the rest of your life, no thank you

I know men can use a gel or cream to increase testosterone, you still need a prescription though

I dont struggle to produce testosterone, got a beard, hairy arms etc. whether its getting to the right places is the question

Even the endocrinologist said you dont want to go down that path of injections as it causes other health problems, thats coming from someone who specialises in this field so..

Posted by: @tryingtohelp2014

ALDH1A1 and 13 cis retinoic acid clearance

ChatGPT

ALDH1A1 is an enzyme that plays a key role in the metabolism of retinoids, including 13-cis-retinoic acid, which is a synthetic form of vitamin A that is used to treat certain types of cancer and skin conditions. 13-cis-retinoic acid is metabolized by ALDH1A1 to a less active form, which can then be further metabolized and excreted from the body.

Studies have shown that ALDH1A1 activity is important for the clearance of 13-cis-retinoic acid from the body, and that decreased ALDH1A1 activity can lead to increased accumulation of 13-cis-retinoic acid and its toxic metabolites, which can cause side effects such as dry skin, mucosal inflammation, and liver damage.

Therefore, maintaining adequate ALDH1A1 activity is important for the effective and safe use of 13-cis-retinoic acid in the treatment of cancer and skin conditions. However, it's important to note that the use of 13-cis-retinoic acid should only be undertaken under the guidance of a healthcare professional, as it can cause serious side effects and should be used with caution in individuals with liver or kidney disease.

 

Yes, that's correct. Copper is an essential cofactor for many enzymes involved in various metabolic pathways, including ALDH metabolism. In particular, copper is required for the activity of ceruloplasmin, an enzyme that oxidizes iron and helps to regulate iron metabolism in the liver. Copper deficiency can lead to decreased ceruloplasmin activity, which in turn can lead to iron accumulation in the liver and decreased ALDH activity.

Copper is also involved in the regulation of gene expression, and copper deficiency can affect the expression of genes involved in various metabolic pathways, including ALDH metabolism. For example, copper deficiency has been shown to decrease the expression of genes involved in retinoid metabolism, which can lead to decreased ALDH activity.

Overall, copper plays an important role in various metabolic pathways, including ALDH metabolism, and copper deficiency can have a significant impact on these pathways.

One example is ALDH1A1, which is involved in the metabolism of retinoids (vitamin A) and is important for the development of various organs, including the eyes, limbs, and heart. Copper has been shown to bind to ALDH1A1 and inhibit its activity, suggesting that copper may play a role in regulating retinoid metabolism.

In addition, copper deficiency has been linked to decreased ALDH activity in the liver, possibly due to the importance of copper as a cofactor for other enzymes involved in ALDH metabolism or as a regulator of gene expression.

Gosh I did a lot around copper theory years ago, started with identifying too much of it via a hair mineral test, kinesiologist puts me on moly zinc to lower it but nothing, no change to anything with my health.

Then the forum here starts throwing around looking into other forms of copper testing, no one knows if we have too much or not enough, Im at hospital pissing into tubes and all that crap which was one way of testing.again nothing conclusive found.

So yeah, all the theory on copper/isotretinoin relationship reads really well but good luck finding anything

Take copper supplements- nothing happens, take moly zinc to reduce copper - nothing happens

Posted by: @truejustice

Posted by: @tryingtohelp2014

ALDH1A1 and 13 cis retinoic acid clearance

ChatGPT

ALDH1A1 is an enzyme that plays a key role in the metabolism of retinoids, including 13-cis-retinoic acid, which is a synthetic form of vitamin A that is used to treat certain types of cancer and skin conditions. 13-cis-retinoic acid is metabolized by ALDH1A1 to a less active form, which can then be further metabolized and excreted from the body.

Studies have shown that ALDH1A1 activity is important for the clearance of 13-cis-retinoic acid from the body, and that decreased ALDH1A1 activity can lead to increased accumulation of 13-cis-retinoic acid and its toxic metabolites, which can cause side effects such as dry skin, mucosal inflammation, and liver damage.

Therefore, maintaining adequate ALDH1A1 activity is important for the effective and safe use of 13-cis-retinoic acid in the treatment of cancer and skin conditions. However, it's important to note that the use of 13-cis-retinoic acid should only be undertaken under the guidance of a healthcare professional, as it can cause serious side effects and should be used with caution in individuals with liver or kidney disease.

 

Yes, that's correct. Copper is an essential cofactor for many enzymes involved in various metabolic pathways, including ALDH metabolism. In particular, copper is required for the activity of ceruloplasmin, an enzyme that oxidizes iron and helps to regulate iron metabolism in the liver. Copper deficiency can lead to decreased ceruloplasmin activity, which in turn can lead to iron accumulation in the liver and decreased ALDH activity.

Copper is also involved in the regulation of gene expression, and copper deficiency can affect the expression of genes involved in various metabolic pathways, including ALDH metabolism. For example, copper deficiency has been shown to decrease the expression of genes involved in retinoid metabolism, which can lead to decreased ALDH activity.

Overall, copper plays an important role in various metabolic pathways, including ALDH metabolism, and copper deficiency can have a significant impact on these pathways.

One example is ALDH1A1, which is involved in the metabolism of retinoids (vitamin A) and is important for the development of various organs, including the eyes, limbs, and heart. Copper has been shown to bind to ALDH1A1 and inhibit its activity, suggesting that copper may play a role in regulating retinoid metabolism.

In addition, copper deficiency has been linked to decreased ALDH activity in the liver, possibly due to the importance of copper as a cofactor for other enzymes involved in ALDH metabolism or as a regulator of gene expression.

Gosh I did a lot around copper theory years ago, started with identifying too much of it via a hair mineral test, kinesiologist puts me on moly zinc to lower it but nothing, no change to anything with my health.

Then the forum here starts throwing around looking into other forms of copper testing, no one knows if we have too much or not enough, Im at hospital pissing into tubes and all that crap which was one way of testing.again nothing conclusive found.

So yeah, all the theory on copper/isotretinoin relationship reads really well but good luck finding anything

Take copper supplements- nothing happens, take moly zinc to reduce copper - nothing happens

https://onlinelibrary.wiley.com/doi/abs/10.1111/jocd.15199

they literally tell you right here it drains copper!! hair tests are a joke. when copper is used up .. it goes into the hair. youre not copper TOXIC! Accutane induces ceruloplasmin like 300% when the treatment starts... and after 6 months, the body is depleted. why??? THATS EXACTLY what this paper says.

this is a chemotherapy drug 1st.... and thats how it works.

how much copper did you take?

what kind?

for how long?

did you have any tests done?

you said you have a problem with T4/T3? guess whats needed for that conversion? copper. please read up on that.

grey hairs on this thread? copper

joint pain? copper

how many more dots have to be connected?

No worries, Ill do some more reading on it - copper & thyroid

Ive taken a few different copper supplements over the years, perhaps Im taking the wrong one or not taking it for long enough.

Does anyone have experience with copper bringing back moisture?? I would think the premature greying of hair has much to do with the dehydration we suffer from post tane surely!? Hair is dry, wiry and brittle, and thinning

What brands can be recommended for copper supplements pls?