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Hi Maynerd,
When I say gall bladder, here's what I mean:
During normal operation, the gall bladder contracts in response to digestive challenge, dumping large amounts of bile right where it's needed.
My gall bladder appears to be sluggish - it does not dump bile.
At first I thought my liver wasn't producing bile. However, a liver blood test did not show elevated liver levels. The only thing off was my TSH (thyroid) levels, which showed me clinically hypothyroid.
In order to correct the sluggish gallbladder, I take the enzyme pills with an enteric coating which dissolves in the lower trat, releasing the bile etc to digest the food.
So, Accutane could have damaged the gall bladder or perhaps the section of the intestine where the gallbladder connects. I don't know. Or it could be related to hypothyroid.
However, I don't see any retoxing pattern. It's a straightforward issue of undigested food creating extremely painful and inflammatory conditions.
I don't seem to need UDCA while taking the digestive enzymes, but I'm not sure about that.
I would say that everyone should try the digestive enzymes, because inflammation related to digestion can manifest in various and unexpected ways, and enzymes and bile can destroy those irritants before they cross into the bloodstream.
Believe, you said that enzymes are expensive??? Mine are generics that cost $7 for a bottle. It literally just says "The Vitamin Shoppe Mult-enzyme: A full spectrum enzyme formula"
Cheers,
JB
For me enzymes are expensive, because they are hard to get through customs and the ones available on the European mainland are expensive. The potent stuff never goes through. Actually I have to correct myself regarding the lasting effect enzymes may have. They can push your body to a new equilibrium if you system is really clogged up with excess protein and fat.
I am quite certain that you (Joseph) - just like probably more than 80% of western society today - still have cholestrol stones in your gallbladder. UDCA will dissolve those stones over time, it takes 3 to 18 months from what I have read. Once the stones are gone your bladder will work more efficiently on a consistent basis.
What about ALA (alpha lipoic acid)? I tried it before, gave me horrible breakouts, but many people recommend it for detox, there are also quite a lot of studies which confirm the positive effect it can have on a wide range of systems related diseases. I even think there is a thread on the holistic forum where somebody got rid of acne by means of ALA.
Well I try to get it through the customs, have tried enzymes before, but what the hell... you still recommend the gold standard product:
https://www.amazon.com/Source-Naturals-Essential-Enzymes-Capsules/dp/B000GFSVPU/
I have started taking UDCA Thursday evening, so I have been taking it now for almost three days and my energy is indeed improved. I have not been sleeping much at all during the last 5 days and been going to bed between 2 and 3 every night while working out pretty hard, almost daily, usually I would be sick in bed already, but I am good. I expect to see further imporvement regarding skin and digestion, but we will see.
I take 250mg in the mornings, 250mg at noon/lunch and 500mg before I go to bed.
Get back to nature y'all to heal yourself.
Processed "food" is poison. It is shit.. Quite literally if you think about it. Processed "foods" are drugs. Most people living in industrialized societies are completed addicted to consuming them. This "food" causes disease.
Start eating natural and you will understand what I am saying.
Peace.
UDCA is the real deal. Here goes my story, please consider that my last week was already very stressfull (see post above). After traveling 5 hours through Germany by means of public transport in horrible weather I finally arrived at my destination in the late evening, that is, the city where I wanted to attend a party of a friend. Got there at about 10:15 and left a little after three in the morning, but before I had to take a couple of friends home, so I did not get to bed before 4. Usually whenever I attend parties I am gone by 2 at the very very latest, because I get too tired. Yesterday was a different story everybody was tired as hell almost exhausted and I could have gone all night.
[Edited link out]
Nothing to do with Accutane, but I've been getting better at music so thought I'd share a track with y'all 
Someone has messaged me suggesting they're improved their health and feel better than before they took Accutane.
They said they wrote everything out and Google Chrome crashed on them, so they'll write to me soon.
Hopefully it's something practical that we can all start doing.
On 10/17/2012 at 9:28 AM, Bosnic said:I think a new thread should be made, that is less blog-ish and more oriented on sharing research and experiences.
Reasearch on what Accutane or what has helped thoose poisoned by accutane? I know the guy from propecia site Awor is looking to work w/ some accutane suffers and combine a site. If that is what you are looking for..... This is a thread A good thread at that, besides theres reasearch and answers in this thread, other threads, sites and you can google any hx or studies on accutane! Not to mention a lot of fourms, sites, threads don't just focus on the research..they have threads and posts that are off topic...It's good to get away from dwelling on things [Edited image out]
I guess my question is what are you looking for?? Do you have a issue that you are looking for answers for?????
Hello! I have not read the entire thread, do not know much English. My opinion on accutane: I was on it for 8 months! Almost clear my acne. The side effects are gone but oily skin came back with bumps! : (
That was my last step. What to do? I tried all the creams and antibiotics!
On 10/18/2012 at 10:31 AM, oli girl said:On 10/17/2012 at 9:28 AM, Bosnic said:I think a new thread should be made, that is less blog-ish and more oriented on sharing research and experiences.
Reasearch on what Accutane or what has helped thoose poisoned by accutane? I know the guy from propecia site Awor is looking to work w/ some accutane suffers and combine a site. If that is what you are looking for..... This is a thread A good thread at that, besides theres reasearch and answers in this thread, other threads, sites and you can google any hx or studies on accutane! Not to mention a lot of fourms, sites, threads don't just focus on the research..they have threads and posts that are off topic...It's good to get away from dwelling on things [Edited image out]
I guess my question is what are you looking for?? Do you have a issue that you are looking for answers for?????
My point is that this thread has bits of good information, but it's hard to find because it's so long. I do a lot of research.
My problem is shared with many, when I eat foods (or supplements) containing retinol, I get the symptoms of being on Accutane:
- joint and bone pain
- hairloss
- warts
- dry skin, flushing
- low energy
My bone density has been shown to be just in the range of "osteoporosis" in some areas, and I attribute this largely to Accutane. Especially considering I'm a teenager. Taking large amounts of vitamin D helps tremendously with joint pain, hairloss and energy. But after a while I felt my energy begginning to drop, I assume it was because of an inbalance of vitamin D to other fat solubles. Right now I'm trying to eat an egg or two every couple days, to at least get some retinol (this is just an experiment). This somewhat aggravates my symptoms (especially joint pain), so I don't know if I'll continue. I also eat plenty of beta-carotene foods, like spinach.
Taking kelp supplementes with selenium has helped energy a lot. The kelp contains iodine, along with selenium this is perfect for thyroid function (Accutane effects your thyroid). And your thyroid is linked to calcium utilization, so I wonder if it would help at all with joint pain.
Eating a paleo-like diet helps tremendously. And I'm sure all that fat intake is helping bile production and excretion. I know some here are into the raw vegan thing, so to each their own.
Things I'm interested in:
- Finding out what causes the long-term effects. It seems to be either:
A) Accutane is still in our systems in some trace amounts (perhaps occupying receptors)
Accutane altered gene expression.
Detox:
This is a way to detox Accutane: The main way Accutane is excreted is through the process of glucuronidation, where glucuronic acid binds to Accutane, and excretes it. Certains enxymes in your body work to break up these bonds. Taking Calcium D-Glucarate has been shown to suppress these enzymes, thus increasing detoxification.
Links:
Accutane metabolism (glucuronidation): http://www.ncbi.nlm..../pubmed/2870901
Accutane lowers glutamine and other anti-oxidants: http://www.ncbi.nlm....pubmed/22517509
I'll let people do their own research. Keywords: "Accutane metabolism", "Calcium D-Glucarate"
Gene expression:
This part is trickier. I think overall making sure you're taking in the other fat solubles vitamins is a good thing (vit d,e,k). Also, I warn people not to avoid retinol for too long. Beta-carotene is poorly turned into retinol. And some of the symptoms people describe are similar in nature to hypovitaminosis A. Try it, and see how you feel. I know some can't tolerate it at all. I can't.
Also, I encourage people to get large amounts of sun exposure. This is crucial for vitamin D (and vitamin D-like compounds not found in supplements.
Interesting links:
- The following link speaks of two patients that were depressed while on Accutane, and taking vitamin A aleviated their depression:
http://www.westonapr...it-of-happiness
Again, try it. Eat a (preferably) natural source of retinol. See how you feel. If it worsens your symptoms drastically, then stop immediately.
On 10/18/2012 at 10:23 PM, Bosnic said:On 10/18/2012 at 10:31 AM, oli girl said:On 10/17/2012 at 9:28 AM, Bosnic said:I think a new thread should be made, that is less blog-ish and more oriented on sharing research and experiences.
Reasearch on what Accutane or what has helped thoose poisoned by accutane? I know the guy from propecia site Awor is looking to work w/ some accutane suffers and combine a site. If that is what you are looking for..... This is a thread A good thread at that, besides theres reasearch and answers in this thread, other threads, sites and you can google any hx or studies on accutane! Not to mention a lot of fourms, sites, threads don't just focus on the research..they have threads and posts that are off topic...It's good to get away from dwelling on things [Edited image out]
I guess my question is what are you looking for?? Do you have a issue that you are looking for answers for?????
My point is that this thread has bits of good information, but it's hard to find because it's so long. I do a lot of research.
My problem is shared with many, when I eat foods (or supplements) containing retinol, I get the symptoms of being on Accutane:
- joint and bone pain
- hairloss
- warts
- dry skin, flushing
- low energy
My bone density has been shown to be just in the range of "osteoporosis" in some areas, and I attribute this largely to Accutane. Especially considering I'm a teenager. Taking large amounts of vitamin D helps tremendously with joint pain, hairloss and energy. But after a while I felt my energy begginning to drop, I assume it was because of an inbalance of vitamin D to other fat solubles. Right now I'm trying to eat an egg or two every couple days, to at least get some retinol (this is just an experiment). This somewhat aggravates my symptoms (especially joint pain), so I don't know if I'll continue. I also eat plenty of beta-carotene foods, like spinach.
Taking kelp supplementes with selenium has helped energy a lot. The kelp contains iodine, along with selenium this is perfect for thyroid function (Accutane effects your thyroid). And your thyroid is linked to calcium utilization, so I wonder if it would help at all with joint pain.
Eating a paleo-like diet helps tremendously. And I'm sure all that fat intake is helping bile production and excretion. I know some here are into the raw vegan thing, so to each their own.
Things I'm interested in:
- Finding out what causes the long-term effects. It seems to be either:
A) Accutane is still in our systems in some trace amounts (perhaps occupying receptors)
Detox:
This is a way to detox Accutane: The main way Accutane is excreted is through the process of glucuronidation, where glucuronic acid binds to Accutane, and excretes it. Certains enxymes in your body work to break up these bonds. Taking Calcium D-Glucarate has been shown to suppress these enzymes, thus increasing detoxification.
Links:
Accutane metabolism (glucuronidation): http://www.ncbi.nlm..../pubmed/2870901
Accutane lowers glutamine and other anti-oxidants: http://www.ncbi.nlm....pubmed/22517509
I'll let people do their own research. Keywords: "Accutane metabolism", "Calcium D-Glucarate"
Gene expression:
This part is trickier. I think overall making sure you're taking in the other fat solubles vitamins is a good thing (vit d,e,k). Also, I warn people not to avoid retinol for too long. Beta-carotene is poorly turned into retinol. And some of the symptoms people describe are similar in nature to hypovitaminosis A. Try it, and see how you feel. I know some can't tolerate it at all. I can't.
Also, I encourage people to get large amounts of sun exposure. This is crucial for vitamin D (and vitamin D-like compounds not found in supplements.
Interesting links:
- The following link speaks of two patients that were depressed while on Accutane, and taking vitamin A aleviated their depression:
http://www.westonapr...it-of-happiness
Again, try it. Eat a (preferably) natural source of retinol. See how you feel. If it worsens your symptoms drastically, then stop immediately.
It sounds like you have some really good answers but how do we know accutane is still in our systems?
On 10/18/2012 at 10:23 PM, Bosnic said:On 10/18/2012 at 10:31 AM, oli girl said:On 10/17/2012 at 9:28 AM, Bosnic said:I think a new thread should be made, that is less blog-ish and more oriented on sharing research and experiences.
Reasearch on what Accutane or what has helped thoose poisoned by accutane? I know the guy from propecia site Awor is looking to work w/ some accutane suffers and combine a site. If that is what you are looking for..... This is a thread A good thread at that, besides theres reasearch and answers in this thread, other threads, sites and you can google any hx or studies on accutane! Not to mention a lot of fourms, sites, threads don't just focus on the research..they have threads and posts that are off topic...It's good to get away from dwelling on things [Edited image out]
I guess my question is what are you looking for?? Do you have a issue that you are looking for answers for?????
My point is that this thread has bits of good information, but it's hard to find because it's so long. I do a lot of research.
My problem is shared with many, when I eat foods (or supplements) containing retinol, I get the symptoms of being on Accutane:
- joint and bone pain
- hairloss
- warts
- dry skin, flushing
- low energy
My bone density has been shown to be just in the range of "osteoporosis" in some areas, and I attribute this largely to Accutane. Especially considering I'm a teenager. Taking large amounts of vitamin D helps tremendously with joint pain, hairloss and energy. But after a while I felt my energy begginning to drop, I assume it was because of an inbalance of vitamin D to other fat solubles. Right now I'm trying to eat an egg or two every couple days, to at least get some retinol (this is just an experiment). This somewhat aggravates my symptoms (especially joint pain), so I don't know if I'll continue. I also eat plenty of beta-carotene foods, like spinach.
Taking kelp supplementes with selenium has helped energy a lot. The kelp contains iodine, along with selenium this is perfect for thyroid function (Accutane effects your thyroid). And your thyroid is linked to calcium utilization, so I wonder if it would help at all with joint pain.
Eating a paleo-like diet helps tremendously. And I'm sure all that fat intake is helping bile production and excretion. I know some here are into the raw vegan thing, so to each their own.
Things I'm interested in:
- Finding out what causes the long-term effects. It seems to be either:
A) Accutane is still in our systems in some trace amounts (perhaps occupying receptors)
Detox:
This is a way to detox Accutane: The main way Accutane is excreted is through the process of glucuronidation, where glucuronic acid binds to Accutane, and excretes it. Certains enxymes in your body work to break up these bonds. Taking Calcium D-Glucarate has been shown to suppress these enzymes, thus increasing detoxification.
Links:
Accutane metabolism (glucuronidation): http://www.ncbi.nlm..../pubmed/2870901
Accutane lowers glutamine and other anti-oxidants: http://www.ncbi.nlm....pubmed/22517509
I'll let people do their own research. Keywords: "Accutane metabolism", "Calcium D-Glucarate"
Gene expression:
This part is trickier. I think overall making sure you're taking in the other fat solubles vitamins is a good thing (vit d,e,k). Also, I warn people not to avoid retinol for too long. Beta-carotene is poorly turned into retinol. And some of the symptoms people describe are similar in nature to hypovitaminosis A. Try it, and see how you feel. I know some can't tolerate it at all. I can't.
Also, I encourage people to get large amounts of sun exposure. This is crucial for vitamin D (and vitamin D-like compounds not found in supplements.
Interesting links:
- The following link speaks of two patients that were depressed while on Accutane, and taking vitamin A aleviated their depression:
http://www.westonapr...it-of-happiness
Again, try it. Eat a (preferably) natural source of retinol. See how you feel. If it worsens your symptoms drastically, then stop immediately.
I am quite aware of the research on Accutane, as I have been a suffer for a long time and was part of a fourm that had alot of info and over 5,000 members some of them who use to be on this board.
What I was trying to get at is that there is research out there, outside of this thread along with this thread.
I am well aware of issues with eating Vit A foods or any products that may have a small amt of Retnoil in them. As there are many foods I don't eat foods that
contain retinol. Some suffers have been found deficent in Vit A after Acccutane and the only way they could withstand taking Vit A is intervenously otherwise they had severe side effects along with thier already destroyed intestines/colon.
Personally I believe it effects gene expression in some and can alter DNA. It is also being studied for possible (very possible) epigentic effects, which would explain why the lingering effects and persistent effects are there long after it has left the body.
James Crandall, PH.D, stated Retinoic acid (active form of Accutane) induces diffrentiation and reduces proliferation of stem and progenitor cells. It works on acne by inducing similar event in basal sebocytes. These same actions also lead 13-cis-retinoic (accutane's) side effects, and these are directed towads proliferating cells in the adult such as in the skin, gut and bone. A wide ranging effect of retinoic acid is to inhibit proliferation in dividing cells, and this accounts for it frequent consideration as a anti-cancer agent.
Not to mention I have severe osteopenia, loss of height while on accutane, 3 autoimmune disorders. By the way try some b12 for energy!
isotretinoin is 13-cis-retinoic acid! Which is a active form of Retinol, Retinoic acid has a 1/2 life, where retinol can be stored in the liver and fatty tissues in the form of retyinl esters.
Not to mention there are a few long time suffers who have acutally had thier liver biopsied and no Isotretinoin was found.
However, who really knows, I mean take a look at Max's bio board, too bad he disappeared and the board has been spammed to death. http://max001.proboards.com/index.cgi
Like I said the guy from the propecia board is looking for a accutane suffer interested in joining together. If you like I will put whoever/you in touch with him.
Hope all is well - Jen
Have any of you thought of oxidative therapy???? The three that are most commonly used parenterally meaning intravenously or by other injection would be ozone therapy, ultraviolet blood irradiation therapy, and intravenous hydrogen peroxide therapy. Believe it or not, a high dose of vitamin C has now been proven to work through oxidation medicines, because it stimulates the production of hydrogen peroxide in the tissues
Just curious!
Has anyone here tried supplementing with Vitamin E or K?
When I take Vitamin K2 my hair feels all stiff, and I get warts (like I did on Accutane). But the other symptoms like joint pain, do not worsen. Very strange.
Oli girl, if the issue is gene expression, I assume making sure you're getting adequate amounts of fat soluble vitamins (besides vitamin A) would help. I think this because there are countless studies showing that the fat soluble vitamins interact heavily in terms of gene expression.
Has anyone here tried supplementing with Vitamin E or K?
When I take Vitamin K2 my hair feels all stiff, and I get warts (like I did on Accutane). But the other symptoms like joint pain, do not worsen. Very strange.
Oli girl, if the issue is gene expression, I assume making sure you're getting adequate amounts of fat soluble vitamins (besides vitamin A) would help. I think this because there are countless studies showing that the fat soluble vitamins interact heavily in terms of gene expression.
Has anyone here tried supplementing with Vitamin E or K?
When I take Vitamin K2 my hair feels all stiff, and I get warts (like I did on Accutane). But the other symptoms like joint pain, do not worsen. Very strange.
Oli girl, if the issue is gene expression, I assume making sure you're getting adequate amounts of fat soluble vitamins (besides vitamin A) would help. I think this because there are countless studies showing that the fat soluble vitamins interact heavily in terms of gene expression.
For me Vit E & Vit K did nothing! Not sure why you would get warts from and your hair would get stiff, acutally there info out there that Vit A (retinol) has shown to improve warts.... though Accutane is know to do odd things, it is like no other drug. What have you done for your warts?
I am not disputing your theroy that it stays in the body, but I don't think it does, and for me eating or taking anything that aids Vit A(retinol) throws me in a bad place. well, even certain beta carotene foods throw me in a bad place.
However, for me I had my Vit A (retinol form) checked 2 months after accutane and was borderline high. Who knows anyways here's more info regarding DNA alteration. Take it for what you want.
Similarly, isotretinoin (13-cis-retinoic-acid), a derivative of retinoic
acid (RA) which is often used to treat severe acne and is also
sometimes used as a chemotherapy medication for prevention and
treatment of certain skin cancers, is such a strong teratogen that
just a single dose taken by a pregnant woman may result in serious
birth defects. When births occur, they are found to have approximately
30% rates of congenital malformation, versus a 35% baseline
risk
[69].
Retinoic acid (RA) mediates many of the functions of vitamin A,
which regulates gene expression by activating intracellular RA
receptors
[70]. The functions of vitamin A are essential for immunological
function, reproduction and embryonic development as
shown by the impaired growth, susceptibility to infection and birth
defects observed in populations receiving suboptimal vitamin A in
their diet. It is now known that RA can influence gene expression
and protein production in many ways
[70]. Genes can respond to
RA through a direct pathway; while others respond through
indirect mechanisms. More than 500 genes have been put forward
as regulatory targets
[70]. Isotretinoins exact mechanism
of action is unknown, but it is known that, like RA, it alters DNA
transcription
[71]. It has also recently been shown to alter DNA
methylation patterns, although it is not yet known if these are direct
or indirect effects
[72]. In any case, the gene expression
changes cause decreased size and output of sebaceous glands,
making the cells that are sloughed off less sticky, and therefore less
able to form comedones. Isotretinoin noticeably reduces the production
of sebum and shrinks the sebaceous glands, and stabilizes
keratinization, preventing comedones from forming. Adverse drug
reactions associated with isotretinoin include dryness of skin, lips
and mucous membranes, infection of the cuticles, cheilitis, skin fragility
and peeling, nose bleeds, dry eyes, conjunctivitis and other
ocular problems, hyperlipidaemia, raised liver enzymes, alopecia,
myalgia and/or arthralgia, headaches and intracranial hypertension,
depression, psychosis, and other psychiatric disorders
[73].
The following adverse effects have been reported to persist, even
after discontinuing therapy, suggesting persistent (or perhaps
slowly-reversing) gene expression changes and epigenetic effects:
alopecia
[73], arthralgias [74], ocular abnormalities [75,76], inflammatory
bowel disease
[77,78], keloids [79], osteopenia [80], hyperlipidemia
[81]
, erectile dysfunction [82], and psychiatric
disturbances
[83]. Isotretinoin is postulated to have complex effects
on the brain and central nervous system. One study utilizing
positron emission tomography (PET) showed functional brain
imaging changes in treated patients
[84].
Stefan dude stay positive!
Start getting back to nature. You will start healing. I guaran-goddam-tee it.
It has only been about 2 months since I started eating real food and it is so obvious to me that I am healing I want to tell everyone!
Just try for a few months not eating processed foods. Eat fruits, vegatables, and natural grain if you want. Fuck the refined shit. It is not food. It is a drug, a poison. Causing every disease you can think of.
And fuck the animal meat. It is fucking disgusting to be honest. A cooked rotting carcass pumped full of drugs. Yummy. This shit does nothing but clog our bodies up, make us fat, and give us cancer. Same goes for milk. Milk is for a damn calf anyway...
I just checked your channel and you have uploaded a video where you read some article about holistic health! Fuck yes! This is the best video you have made hands down. Now just try it and you will heal!
[Edited link out]
Here are some common fruits and herbs that have been very helpful for me and can help everyone else too.
- Apples ([Edited image out])
- Oranges (awesome and water packed)
- Lemons (amazing cleanser, great for jaundice)
- Romaine Lettuce (just great, tasty and full of minerals)
- Dandelion (one of the best liver healers on this planet)
- Onions (you don't even have to eat it. try just peeling one by your face)
- Mushrooms (yeah!)
Just a small list. There are so many other plants that have their own healing benefits. Note though they are not very effective if you still eat chemical junk food.
On 10/20/2012 at 12:12 AM, Connor McElvain said:Stefan dude stay positive!
Start getting back to nature. You will start healing. I guaran-goddam-tee it.
It has only been about 2 months since I started eating real food and it is so obvious to me that I am healing I want to tell everyone!
Just try for a few months not eating processed foods. Eat fruits, vegatables, and natural grain if you want. Fuck the refined shit. It is not food. It is a drug, a poison. Causing every disease you can think of.
And fuck the animal meat. It is fucking disgusting to be honest. A cooked rotting carcass pumped full of drugs. Yummy. This shit does nothing but clog our bodies up, make us fat, and give us cancer. Same goes for milk. Milk is for a damn calf anyway...
I just checked your channel and you have uploaded a video where you read some article about holistic health! Fuck yes! This is the best video you have made hands down. Now just try it and you will heal!
[Edited link out]
Here are some common fruits and herbs that have been very helpful for me and can help everyone else too.
- Apples ([Edited image out])
- Oranges (awesome and water packed)
- Lemons (amazing cleanser, great for jaundice)
- Romaine Lettuce (just great, tasty and full of minerals)
- Dandelion (one of the best liver healers on this planet)
- Onions (you don't even have to eat it. try just peeling one by your face)
- Mushrooms (yeah!)
Just a small list. There are so many other plants that have their own healing benefits. Note though they are not very effective if you still eat chemical junk food.
Thank you for the words of encouragement Connor.
I think I find it hard to find the motivation to do it.
I really want to, and will do my best, because I'm sick of feeling this awful, and I trust you.
But, I find it hard because I already eat really well by most people's standards, and I think 'Why am I not even a little better?'
Then I read stuff online about people having these side effects for years and years, and developing things like diabetes and IBD.
Scared the shit out of me, to be honest, and makes me feel helpless... Like nothing I do makes any difference.
And I still think about the Vitamin A toxicity possibility and stuff.
Although I clearly have digestive problems (always constipated and still have those lovely hemmorhoids), food seems to be the one thing that makes me feel a bit better (in the short term).
Connor - Do you find it hard to stick to your diet? Do you get bored? Was it harder in the beginning? Do you have any advice as to how I could transition?
Do you eat organically?
I find it hard to think of a diet that revolves just around veg/fruit.
I'd feel like I'd not eaten all day, if I hadn't had meat, or something...
It's hard not to get overwhelmed with conflicting information...
Some say we need mostly protein and good fats.
Many vegetarians seem to look old/ not age too great (I know there are other factors).
Dunno.
I just want to get away from thinking about health every second.
Seems things have just got even worse this last year or so.
I never seem to have a clear head. Always feels like I have a slight headache.
I definitely need to cut a lot of shit out though.
Me and my girlfriend often snack on a big bag or crisps, or sweets, or something, at night.
I think - like most people - I'm addicted.
Stef
This seems to be a good price, and a good juicer:
[Edited link out]
Need some f*cking money!!!!!!!!!!!!!!!!!!!!!!!
P.S..
Connor - What improvements have you been seeing?
Was your energy at a real low before you made diet changes?
Cos mine sure as hell is right now! Feel like a 90 year old.
Work is humiliating at best, and impossible at worst.
Also, what good does putting an onion in front of you do? lol
It's interesting that they ponder the idea that gene expression changes caused by RA maybe be slow to reverse. It can reverse?
The warts I only get when I consume retinol. They first appeared while I was on Accutane.
When I took Accutane, I assume I was heavily deficient in Vitamin D, because of lack of sun exposure. I think this may have left many receptors "unoccupied", and vulnerable to the effects of Accutane on gene expression. When I get large amounts of sun exposure I feel great, which is understandable.
Does anyone else here think they may have been deficient in Vitamin D when taking Accutane? This may be part of the cause.
Note: You said that some people who have taken Accutane can only handle retinol when it is injected ultravenously. I've also heard accounts of people that said they felt large remision from their side-effects when conducting a bowel cleanse type program, one person also mentioned colonix.
Perhaps the answer lies in the gut? (or at least part of it)
It's interesting that they ponder the idea that gene expression changes caused by RA maybe be slow to reverse. It can reverse?
The warts I only get when I consume retinol. They first appeared while I was on Accutane.
When I took Accutane, I assume I was heavily deficient in Vitamin D, because of lack of sun exposure. I think this may have left many receptors "unoccupied", and vulnerable to the effects of Accutane on gene expression. When I get large amounts of sun exposure I feel great, which is understandable.
Does anyone else here think they may have been deficient in Vitamin D when taking Accutane? This may be part of the cause.
Note: You said that some people who have taken Accutane can only handle retinol when it is injected ultravenously. I've also heard accounts of people that said they felt large remision from their side-effects when conducting a bowel cleanse type program, one person also mentioned colonix.
Perhaps the answer lies in the gut? (or at least part of it)
I posted this once before on pg 2 of this thread...Vit A & Vit D compete against eachother, they have a important relationship and there are studies that show Accutane depletes Vit D.
Omega-3 fats and other moulecules bind to Vitamin A receptors. Same as Vitamin D is also the most important partnership with Vit A and Omega's.
Retinoids, Vit A, Vit D, Thyroid hormones is in a group called the steroid family. This family is known for developing partnerships w/other hormones (such as growth hormones) They all bind to nuclear receptors, meaning they have acess to the nucleus, where they influence gene expression.
When you have either Vit A or Vit D it almost always does so in partnership with Vit A receptor, which binds vitamin A or the omega-3 fatty acid DHA. In the nucleus of the cell, it sits as judge and jury, deciding which genes are turned on and which are turned off. Vit D and its partners Vit A and DHA (omega 3) are conducting the orchestra.
(book written by James E. Dowd, M.D. from Mi Arthritis Institute)
http://www.ncbi.nlm....pubmed/21410620
Therapeutic hotline. Does isotretinoin have effect on vitamin D physiology and bone metabolism in acne patients?
Ertugrul DT, Karadag AS, Tutal E, Akin KO.
Source
Department of Internal Medicine, Ankara Kecioren Research and Training Hospital, Ankara, Turkey. [email protected]
Abstract
Isotretinoin is an effective therapy for severe nodulocystic acne. Several experimental studies suggest that it may have an effect on vitamin D physiology. In the present study, the authors aimed to investigate the effect of isotretinoin treatment on the metabolism of vitamin D in acne patients. A prospective analysis of 50 consecutive acne patients who were treated with isotretinoin for 3 months was done. Before and after 3 months of treatment, 25 hydroxy vitamin D, 1,25 dihydroxy vitamin D, and bone alkaline phosphatase, calcium, phosphate, and parathormone levels were measured. The 25 hydroxy vitamin D and serum calcium levels decreased significantly (p < 0.0001, p < 0.05, respectively), whereas 1,25 dihydroxy vitamin D, parathormone, and bone alkaline phosphatase levels increased significantly after 3 months of isotretinoin treatment (p < 0.005, p < 0.005, p < 0.0001, respectively). Aspartate aminotransferase, total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels also increased significantly after isotretinoin treatment. This prospective clinical study showed that isotretinoin has an effect on vitamin D metabolism. Further clinical studies with longer periods of follow-up are needed to understand the effect of isotretinoin on vitamin D and bone metabolism.
Serum levels of vitamin D metabolites in isotretinoin-treated acne patients.
Rdland O, Aksnes L, Nilsen A, Morken T.
Source
Department of Dermatology, University of Bergen, Haukeland Hospital, Norway.
Abstract
Serum levels of vitamin D metabolites were determined in 11 patients treated for cystic acne with a four-month course of isotretinoin (Roaccutane). The levels were measured before treatment and after two months of medication. We found a significant fall in the level of 1,25-dihydroxyvitamin D (p less than 0.01) and a significant increase in the molar ratio of 24, 25-dihydroxyvitamin D to 25-hydroxyvitamin D (p less than 0.05). No significant changes were found for the vitamin D metabolites 25-hydroxyvitamin D or 24,25-dihydroxy-vitamin D, for serum calcium, phosphorus, alkaline phosphatase or parathyroid hormone. Our data indicate early changes in the metabolism of vitamin D in patients on retinoid treatment.
PMID:1357865[PubMed - indexed for MEDLINE]