Acne.org Products
Anyone know exactly how accutane causes hairloss. I know that during treatment, your hairs go sooner into telogen but how can it effect the hair after treatment. Personally, my hair was fine during treatment, just a bit drier. But the months after I stopped, my hair turned to shit. I probably have a bit regular mpb but what bothers me the most is the texture and quality. It's brittle and lost a lot of density. I searched on hairlossforums and there isa theory that due to the downregulation of 5AR 1 due to accutane, 5AR 2 is being upregulated to compensate. There was also someone who cured his accutane induced side effects by taking finasteride. But how would that work exactly?
I highly doubt anyone cured themself of accutane damage by poisoning their body with another toxic poison. Sounds like a finasteride sales rep troll trying to muster more finasteride sales from anyone dumb enough to listen.
I never, ever experienced any tinnitus in the 29 years post accutane until just recently. Now it's non stop. What prompted it? An amino acid combination of phenylalanine and citrulline a couple days ago. My theory is the drug is still in the body, and citrulline's ability to induce nitric oxide caused some movement in my lymph system, enough movement to induce the tinnitus I'm now dealing with.
I've dropped the seaweed (too much soluble fiber wiping out my already low cholesterol), phenylalanine and citrulline (too much dopamine loss from citruline), keeping the whole beef liver in the mix, and added fish eggs and tmg. Fish eggs are rich in omega 3 and lecithin. Lecithin activates Lrat enzyme, which I believe is key. Tmg replenishes glycine, which accutane depletes due to upregulating gnmt enzyme. Will see how these three supplements go over the coming weeks. Take care.
On 3/26/2021 at 2:13 AM, MonsterDiesel said:Had anyone here benefited from taking thyroid hormones, either T3 or T4, regardless of lab tests and actually felt better?
Going to try this route myself. My tests are low normal but all my symptoms are indicative of hypothyroidism. Been feeling pretty rundown actually.
Are you talking about supplements or something stronger?
Id find it hard to get something strong unless a test was conducted that clearly indicatesthyroid problem and a prescription given.
We all know many thyroid tests are never clear cut so what do you do?.....
Daily supplements
Collagen 6
Codeage pancreas 6
Ancestral fish eggs 6
Now L Phenylalanine 3
Vitamin c gummies, as desired
Diet
Omnivore
Organic when possible
cholesterol is the precursor to all hormones, including testosterone. Fish eggs are loaded with cholesterol. Glycine is the catalyst for transforming testosterone into dht via 5 alpha reductase. Dht is far more important than testosterone. Collagen is loaded with glycine. Will see how this program goes. Take care.
On 3/22/2021 at 6:00 AM, Lifesuckshard said:It would make your skin produce more oil and improve insulin resistance. My bloodsugar is always very high since accutane and I can't gain any weight or muscles no matter how much I workout or what I eat. A side effect of this medication is general weight gainbut it reduces abdominal fat. Post-accutane, the skinbarrier can't lock water and moisture very well and TZD's should improve the skin barrier. I don't know if this would also help for dry eyes. The question would be how long you should take it.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500869/
It was used to treat frontal fibrosing alopecia and there was one patient who was treated with 15 mg pioglitazone daily and after 8 months, the disease was stabilized. There was no further hair loss or inflammation after one year post-treatment follow-up.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500869/
A patient with progressive MS was treated with 45 mg pioglitazone daily for 3 years. After these 3 years, there was clinical improvement without adverse events.
Life sucks the reason your blood sugar is always high post accutane is a malfunctioning pancreas. Beef pancreas helps to correct a malfunctioning human pancreas. Dr Ron's, Codeage, ancestral supplements, and nutricology are some brands that sell beef pancreas.
Also, collagen is known to greatly improved hair health.
11 hours ago, Aaron76 said:Life sucks the reason your blood sugar is always high post accutane is a malfunctioning pancreas. Beef pancreas helps to correct a malfunctioning human pancreas. Dr Ron's, Codeage, ancestral supplements, and nutricology are some brands that sell beef pancreas.
Also, collagen is known to greatly improved hair health.
Thanks I'll give it a try
On 3/26/2021 at 9:58 PM, DeepAcceptance said:For anyone that is looking to improve their testosterone, apparently magnesium and zinc are beneficial!
Many things are beneficial. Not just MAG and Zinc. Look into my profile, I made a few posts about libido and raising T, with a Dropbox link for studies. Among the things that also raise libido/T are TONGKAT ALI and FENUGREEK. If you look into the Now Foods page from Amazon (for example) you'll see reviews from men claiming this worked. Of course if possible avoid this and other companies putting crap in fillers/additives, since this one has MAG stearate and silicon dioxide.
The few studies I collected can be read here: (fixed link)
https://www.dropbox.com/sh/hlck885uu1jvi52/AABkIrjGGVjmSNpjsI5m6rDMa?dl=0
You also need to check into Tribulus Terrestris, and peruvian MACA. There are many changes that can help with that and other side effects, to list everything here would be impossible. Checking into my profile you can read my previous messages.
Magnesium and zinc, just like vitamin D-3 + K-2, are crucial supplements for anyone to use. Just be careful to not overconsume calcium foods while taking any D-3. It's best to avoid or make that not on a daily basis, and limit in your diet to under 500 mg. Also increase magnesium (elemental to 400 mg) daily if you take D-3. Spread the MAG capsules over the day. MAG, just like K-2 (MK-7 only)iscrucial to avoid stuff like soft tissue calcification. Remember D-3 increases calcium absorption, so it would be very unwise to take a higher D-3 dose and stuff your body with calcium and little MAG/K-2 (the last two compete with calcium for absorption, and prevent it from doing damage inside the body).
On 3/25/2021 at 10:13 AM, MonsterDiesel said:Had anyone here benefited from taking thyroid hormones, either T3 or T4, regardless of lab tests and actually felt better?
Going to try this route myself. My tests are low normal but all my symptoms are indicative of hypothyroidism. Been feeling pretty rundown actually.
I had a thyroid panel done a few years back for a few suspicions I had unrelated to acne. They came back on the lower edge of normal along with my testosterone. I was concerned and started advocating for further treatment.I was told time of day to which the tests are drawn havea big impact on final results. To me that was surprising at first, but it does make some sense. I do question how much the results are decreased when drawn in the afternoon vs morning like I had done. That said, I would get another test in the morning sometime down the road and trend the results.
13 hours ago, Perene said:Many things are beneficial. Not just MAG and Zinc. Look into my profile, I made a few posts about libido and raising T, with a Dropbox link for studies. Among the things that also raise libido/T are TONGKAT ALI and FENUGREEK. If you look into the Now Foods page from Amazon (for example) you'll see reviews from men claiming this worked. Of course if possible avoid this and other companies putting crap in fillers/additives, since this one has MAG stearate and silicon dioxide.
The few studies I collected can be read here: (fixed link)
https://www.dropbox.com/sh/hlck885uu1jvi52/AABkIrjGGVjmSNpjsI5m6rDMa?dl=0
You also need to check into Tribulus Terrestris, and peruvian MACA. There are many changes that can help with that and other side effects, to list everything here would be impossible. Checking into my profile you can read my previous messages.
Magnesium and zinc, just like vitamin D-3 + K-2, are crucial supplements for anyone to use. Just be careful to not overconsume calcium foods while taking any D-3. It's best to avoid or make that not on a daily basis, and limit in your diet to under 500 mg. Also increase magnesium (elemental to 400 mg) daily if you take D-3. Spread the MAG capsules over the day. MAG, just like K-2 (MK-7 only)iscrucial to avoid stuff like soft tissue calcification. Remember D-3 increases calcium absorption, so it would be very unwise to take a higher D-3 dose and stuff your body with calcium and little MAG/K-2 (the last two compete with calcium for absorption, and prevent it from doing damage inside the body).
I've taken everything you've described, religiously. Two issues came up: either no observable results that showed definite results to prove it wasn't a placebo effectand no way to actual validate either wayi.e., free T level before treatment vs. after. I could have pushed harder to get a blood test, but I didn't.
Second, I am trusting the company with my life that the product/s I'm using actually have said amount of ingredients and not fillers that are toxic. A consumer study years back found variances of 25-100+% difference between what was advertised and what the product actually contained which also varied per batch of the product from the same company. I believe like 20 companies were included in this examination. Names hidden for fear of backlash. So, I think this is a great idea, but you need to find a very reputable company. In my opinion on this, no walmart, target, GNC brand is reliable, consistently. If I had to make a suggestion and also remind anyone that reads this that I am not a shill and nor do I have any financial benefit or ties to this company,Nootropics Depot has provided consistent results for me. I use their sleep support and it has been a fantastic success that is better than dosing antihistamines,or sleep aides all of which just mess with consciousness rather than promoting physiologic processes. They have a subreddit which is an extremely helpful community.
@k3tchup have u taken accutane?
@k3tchup That's why I always say that for optimal health supplements account for 1/3 of the results. 1/2 of what you call "health" can only come from the "trifecta" DIET + EXERCISES + SLEEP.
If (for example) the goal is to raise testosterone/libido, and one of these things is amiss, then you can be 100% sure you'll flop.
Why? Because even being inactive and not having a workout routine aimed for the goal of increasing T will harm a lot the results.
Bad sleep will for sure drop A LOT your levels. And I don't mean just sleeping for 8 hours, I am talking about HOW YOU SLEEP, stuff like optimal temperature for this moment, killing all possible lights and making the bedroom 100% dark, not using electronics too close to sleeping time, the little details when combined DO MATTER.
Then there are also toxins that will gradually make you more and more sick, like EMF radiation (all 3: RF, magnetic and electric fields), BPA/endocrine disruptors, personal care products with clean ingredients, how clean is the water you are drinking, etc. etc.
A supplement isn't a magic pill just like a COVID vaccine isn't going to prevent you from being infected (it will only decrease the chances of you becoming really sick)and turning you into Highlander. Even Highlander isn't immortal, if you cut his head he will die. It's a delusion to think anything will be OK if you do it the easy way.
What people really neededwas toboost theirimmune system in advance, before theyare infected by any virus. It's idiotic to do this when it's too late.
A supplement is useful when the diet can't provide what we really need. And over time the diet, workout routine, and even supplements (some definitelly will need cycling) will need to be changed, even if slightly. Unfortunately that also means more appointments with a dietitian, personal trainer or whatever that is treating you. But that's how it is.
What I wouldn't expect is results in a few weeks. More like months, and depending on the damage from decades of neglect in your body, with bad habits and diet, perhaps even YEARS. I was about to start going to the gym and for the first time start a new routine, to really work harder for tangible results, and add a few supplements. That idea was scrapped after COVID and since March 2020 I am not going to one, because the idea of wearing a mask during exercise is ridiculous, and to get infected in a gym is a lot more easier. So I am not even bothering with anything that is not essential now.
Not all Accutane side effects are going to affect the people that did the treatment for all their lives. The depression I had a while after was gone, it resolved itself. What I feel like is that most people aren't doing enough in terms of diet + sleep + exercise + correct supplements + removal of toxins and at the same time they aren't checking blood levels for a few things they should.
For example, anyone complaining about low libido/testosterone needs to check the BEFORE and AFTER of:
- Free T
- Total T
- Estradiol
- DHT
- LH
- FSH
- Prolactin
- Vitamin D
Since I have a suspicious Accutane messes with a few of those, if not all of them. What prevents any discoveries is these people not trying what I said first, before they claim nothing will work. TRT I am against unless the levels are really lowand adoctor recommends as the only way to fix. Because it's not a natural routeand has some bad side effects long term. If we could fix ourselves with a little more effort, without any drug from Big Pharma, then it would be more preferable.
On 4/3/2021 at 11:04 PM, Perene said:@k3tchup That's why I always say that for optimal health supplements account for 1/3 of the results. 1/2 of what you call "health" can only come from the "trifecta" DIET + EXERCISES + SLEEP.
If (for example) the goal is to raise testosterone/libido, and one of these things is amiss, then you can be 100% sure you'll flop.
Why? Because even being inactive and not having a workout routine aimed for the goal of increasing T will harm a lot the results.
Bad sleep will for sure drop A LOT your levels. And I don't mean just sleeping for 8 hours, I am talking about HOW YOU SLEEP, stuff like optimal temperature for this moment, killing all possible lights and making the bedroom 100% dark, not using electronics too close to sleeping time, the little details when combined DO MATTER.
Then there are also toxins that will gradually make you more and more sick, like EMF radiation (all 3: RF, magnetic and electric fields), BPA/endocrine disruptors, personal care products with clean ingredients, how clean is the water you are drinking, etc. etc.
A supplement isn't a magic pill just like a COVID vaccine isn't going to prevent you from being infected (it will only decrease the chances of you becoming really sick)and turning you into Highlander. Even Highlander isn't immortal, if you cut his head he will die. It's a delusion to think anything will be OK if you do it the easy way.
What people really neededwas toboost theirimmune system in advance, before theyare infected by any virus. It's idiotic to do this when it's too late.
A supplement is useful when the diet can't provide what we really need. And over time the diet, workout routine, and even supplements (some definitelly will need cycling) will need to be changed, even if slightly. Unfortunately that also means more appointments with a dietitian, personal trainer or whatever that is treating you. But that's how it is.
What I wouldn't expect is results in a few weeks. More like months, and depending on the damage from decades of neglect in your body, with bad habits and diet, perhaps even YEARS. I was about to start going to the gym and for the first time start a new routine, to really work harder for tangible results, and add a few supplements. That idea was scrapped after COVID and since March 2020 I am not going to one, because the idea of wearing a mask during exercise is ridiculous, and to get infected in a gym is a lot more easier. So I am not even bothering with anything that is not essential now.
Not all Accutane side effects are going to affect the people that did the treatment for all their lives. The depression I had a while after was gone, it resolved itself. What I feel like is that most people aren't doing enough in terms of diet + sleep + exercise + correct supplements + removal of toxins and at the same time they aren't checking blood levels for a few things they should.
For example, anyone complaining about low libido/testosterone needs to check the BEFORE and AFTER of:
- Free T
- Total T
- Estradiol
- DHT
- LH
- FSH
- Prolactin
- Vitamin DSince I have a suspicious Accutane messes with a few of those, if not all of them. What prevents any discoveries is these people not trying what I said first, before they claim nothing will work. TRT I am against unless the levels are really lowand adoctor recommends as the only way to fix. Because it's not a natural routeand has some bad side effects long term. If we could fix ourselves with a little more effort, without any drug from Big Pharma, then it would be more preferable.
I agree. Supplement/s is/arepart of the overall picture of health and do exactly as their name intends. I cant agree more. I know my diet is deficientin daily fiber intake and magnesium for example. Supplements used correctly do help support the overall picture. Studies that say otherwise are not well organized nor specific. I only question the companies integrity in the products they sell. Without a lab, the consumer is taking the company for its word that the product is safe, with predictable levels of their product. Exercise, and sleep are the secrets of longevity and studies support this.
Sleep is fascinating. Mathew Walkers book on Why we sleep is a great read if anyone is into reading or if anyone has a long drive ahead of them Peter Attias The Drive podcast hosts Mathew a few times as he goes over many of the hot topics in sleep and sleep research.
Ideally everyone of us would have access to lab tests and bio markers that could give us insight as to why we have the symptoms we have. Unfortunately, that isnt attainable, feasible, cost effective, and the tests are single points in time that provided limited inference. Really we need to do them over time to trend data and control for variables to get a cleaner idea of what may* be going on. But what you say is what we should do if we can.
My current theory is that the microbiome plays the largest role with our issues. Humans are 90% bacteria. I believe accutane wiped out a lot of beneficial bacteria, promoted the growth of a lot of bad bacteria, and until that balance is corrected, the issues remain. For some people who took accutane and say they have no issues post accutane, it's likely because their gut microbiome remained intact. For us, our microbiome is still out of whack years later. The below protocol is intended to correct the gut microbiome. Will post results, hopefully good, when available. Take care.
Daily supplements
Kyolic original 2x2/day
As needed for rls
Now L phenylalanine
Diet
Omnivore
Organic when possible
Fenugreek and maca are estrogenic. Zinc inhibits dht via 5 alpha reductase. Magnesium is no good for anyone who already deals with loose stools. Magnesium is excellent and highly recommended for anyone who deals with chronic constipation. Tribulus is good for T, but can cause jitteriness in some people. Vitamin d is a hormone that when kept at or below 100% us rda can be good, but can and does do more harm than good above that, since it then creates a hormonal imbalance. L Phenylalanine is an essential amino acid that helps boost dopamine and lower excess serotonin, and is excellent for rls. L Phenylalanine is far superior to tyrosine, since it can do more positive things in the body.
So if you didn't watch Garret Smith's video, what he points out is that 13-cis-retinoic acid destroys the Leydig cells in the testicles.
The Leydig cells are responsible for producing testosterone which is why we are all suffering from low testosterone and libido. The question remains, how to get the Leydig cells to start replicating. From my knowledge most of Leydig cell replication happens as a fetus so it seems unlikely that we can get them to replicate at our age. One thing that I have learned is that stem cell replication starts to happen progressively during a water fast and reaches peak velocity at about 20 days. This might seem extreme but you might have to go 40 days to have some sort of significant change. I have heard of people healing from finasteride by doing a 20 day water fast but Accutane causes much more fundamental damage. Currently modern medicine doesn't have a way of getting the Leydig cells to replicate.
What Garret Smith says is that Vitamin A destroys Leydig cells in the testicles. Personally, my testicles were reduced in size and my testosterone has been extremely low.It has taken 8 years for me to understand why this happened. I am extremely disappointedin the scientific community for not doing anything about this and keeping this drug on the market. There are people a lot smarter than myself that were involved in making this drug and probably know what vitamin A toxicity does to the human body and have not done anything about this. It is likely that we are stuck like this for life because Leydig cell replication mostly happens in the womb. It is hard to say if the direct reason that acne disappearsis a direct result of Leydig cell apoptosis(programmed cell death) and the resulting lowering of testosterone since testosterone causes larger, more oily pores.
