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Repairing the long-term damage from Accutane

 
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8
(@dthtodrmtlgsts)

Posted : 08/16/2012 2:38 am

I wish this UDCA was legal here so we could A. actually get it B. know the source C. know how it was extracted. The methods seem to be getting more humane but there's no way to tell when you get it from oversees. Interestingly though, I took 2 pills of my Cholacol before lunch today due to ppl's success with udca/tudca and I started to wonder if we've found a key organ for our success with the gallbladder connection. I felt kinda crappy and nauseous today before lunch and I usually feel tired and crappy after lunch even though I usually only eat salads for lunch. But today I feel better than I did before lunch. The only thing I did different today was take my cholacol. All it is is one herb that cleanses the liver and bile salts... Will of course report back to see if results are consistent.

 

btw, I still recommend Oxyal even though indigo didn't see results. I got the filmy thing when I first started taking them too but floaters have been down by 80% on a consistent basis. I'd say try one drop right before bed and one in morning or as needed.

 

 

Have anybody else had ultrasound of their gallbladder? I did, and there is some stuff in there that should not bee there, the doctors said it was polyps, many of them, small, should not be dangerous. Polyps are much rarer than stones, but so they said. Coming back to my country i think it could have been a loss in translation so that the pollyps are actually stones. They gave me some green and brown pills that should stop the polyps/stones from groving more and might actually remove them. I newer knew what it was, but maybe it was something like udca, as i see that is the main application for it and i was in china:o I stopped taking them because i was so unsure of what it was and i did not hurt in the gallbladder area. Still got some bottles though. How long and how much must one use before feeling any different?

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2
(@janski)

Posted : 08/16/2012 2:01 pm

I've been stalking this forum for what seems like ages and decided to come out as yet another accutane victim. Most of what I learned about what it had done to me was from all you guys and I'm so thankful I stumbled upon this forum. I've been to the ER, psychologists, so many doctors I can't even count them all. Was "diagnosed" with reactive hypoglycemia, some type of stress disorder at one point, depression. For months I had what seemed like no emotions, insane panic attacks, and just an overall change of what my life used to be like before accutane. I was on it for six months before I went to the ER, I felt like I was dying. The lack of energy was the worst. I had ADD before even taking accutane, then I felt as if my focus was destroyed after those 6 months. Anyways, before I write a book about what you guys already know, I'll continue to stick around here and help in any way to make sure nobody else goes through what I did and still do every day. If I lived in Switzerland Roche wouldn't be happy, I'd do anything to take them down..

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143
(@indigorush)

Posted : 08/16/2012 3:48 pm

I've been stalking this forum for what seems like ages and decided to come out as yet another accutane victim. Most of what I learned about what it had done to me was from all you guys and I'm so thankful I stumbled upon this forum. I've been to the ER, psychologists, so many doctors I can't even count them all. Was "diagnosed" with reactive hypoglycemia, some type of stress disorder at one point, depression. For months I had what seemed like no emotions, insane panic attacks, and just an overall change of what my life used to be like before accutane. I was on it for six months before I went to the ER, I felt like I was dying. The lack of energy was the worst. I had ADD before even taking accutane, then I felt as if my focus was destroyed after those 6 months. Anyways, before I write a book about what you guys already know, I'll continue to stick around here and help in any way to make sure nobody else goes through what I did and still do every day. If I lived in Switzerland Roche wouldn't be happy, I'd do anything to take them down..

 

 

Including getting on a plane and risking prison? haha

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MemberMember
2
(@janski)

Posted : 08/16/2012 3:55 pm

Prison is only for the people who are stupid enough to get caught! [Edited image out]aha. Nah I wouldn't stoop to that level, but I still have a hatred for whoever was involved in marketing accutane for acne.

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143
(@indigorush)

Posted : 08/16/2012 4:15 pm

Yeah.. Don't we all.

But from a spiritual point of view (and I'm hardly Gandhi) we shouldn't spend lots of time being angry and hateful against anyone, especially a bunch of faceless guys who made this drug.

Yepp, we'd all like to make them pay for what they've done to us and our bodies, but we can't.

We all need to work towards acceptance, in terms of accepting that we are where we are and bad things can happen.

We're very wise about health and medicine now, so at least we've learned something.

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Janski, Janski and Janski reacted
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(@highlight)

Posted : 08/16/2012 11:11 pm

I traded an acne-prone face for a dried up, wrinkly, aged skin face 4 months post-drug. Picked my poison (literally.)

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91
(@josephbuchignani)

Posted : 08/17/2012 8:31 am

@dthtodrmtlgsts it takes me only 2-3 hours for chronic fatigue to dissipate. I take a gram at 180 pounds.

 

Maynerd, bear bile is vastly more expensive, anything you get on the internet will be synthetic unless heavily advertised otherwise.

 

@CHIRON The bile bears have nothing to do with the pills you buy unless they're Traditional Chinese Medicine.

 

@Darksonic Good luck, I really hope this works for others as well.

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157
(@chico-esposito)

Posted : 08/17/2012 10:02 am

Been taking Aegis TUDCA for about 15-20 days but haven't noticed any improvement in my very light coloured stools whatsoever. Found a packet of thermolife liver longer i had from ages ago with 20 pills left. Took 2 a day for 3 days so far and instantly i'm feeling sensations in my gallbladder after eating. My stools are for the first time in ages getting darker in colour. Thats within three days, i don't know what they put in aegis but i'm very suspicious about the quality of that product. Someone said the bodybuilding supp market is unregulated and they are right. I doubt the amount of tudca is in that product as they claim. Thermolife liver longer works though. I can vouch for that 100%, sadly it's been discontinued, which is devastating.

 

Is there anywere you can get proper UDCA / thermolife liver longer in the uk?

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MemberMember
157
(@chico-esposito)

Posted : 08/17/2012 10:25 am

baking soda / water paste to clean the skin or scalp of sebborheic dermatitis

 

ingredients- baking soda, water, cetaphil gentle skin cleanser, bowl, spoon.

 

Directions - get the bowl and put 3- 4 heaped tablespoons of baking soda into the bowl, add a few tablespoons of water until it forms a paste that can be easily applied to the skin. Then apply to the face / scalp or both gently applying until the face is covered (don't drag, just pat onto skin). Let sit for at least 10-15 minutes then fill the sink with warm water. Place your head into the water and slowly move your head from left to right. You don't need to be aggressive with it, just gently move your face around in the water. The baking soda dissolves in water without any effort whatsoever. If it's for the scalp get your shower head and rinse your hair dry. Pat face / Pat hair dry with a towel.

 

I suffer from spontaneous scarring of the skin from my sebborheic dermatitis, if i apply any force in removing the seb derm from my skin, by force i mean any exfoliating products or even rubbing my skin it causes scarring of my face because it's that sensitive. This is the most non invasive way i've found to remove the dead skin / plagues ( seb derm) thats constantly growing on my face and scalp.

 

Also applying cetaphil gentle skin cleanser afterwards liberally and washing after 10-20 minutes can loosen the dead skin / dermatitis and it's easier to remove. But this is only after the baking soda.....thats the one that works although do it every 2-3 days as it can be harsh on the skin if it is an everyday thing. Hope that helps some with dermatitis / very dry peeling skin as a result of accutane side effects.

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91
(@josephbuchignani)

Posted : 08/17/2012 12:54 pm

That's awesome news Chico! I'm happy to ship UDCA at cost if you can't find a local source. The gradual improvement you're noticing with TUDCA sounds similar to my experience.

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MemberMember
0
(@frenchy45)

Posted : 08/17/2012 1:44 pm

For sebborheic dermatitis try a bag of green tea (hot or cold) on your face,

for me it worked instantly.

 

A real miracle after all these years of ''hot skin'' caused by dermatitis, finally i can take a shower and shave without worrying.

 

You should try it asap.

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3
(@mahweeoh)

Posted : 08/17/2012 2:31 pm

 

Hi been following your thread some more. I had a question about Accutane. Is it the already converted form of vitamin A? In other words, the body converts it to tretinoin or w/e it is? Because if that's so I guess that explains the toxicity--forcing pre-converted forms of the vitamin itself into the body. So what is your take on vitamin A supplementing then? I decided to forgo Accutane, tried some vitamin A supplementation ( in safe amounts ) and my acne exploded, or rather it purged what was already just sitting there under the skin but wasn't budging. The odd thing is it cleared up the right side of my face completely, but not the left. It looks odd lol.

 

So would using higher doses of vitamin A possibly be safer because your body is converting it to it's liking rather than forcing pre-converted ( not to mention synthetic ) stuff into your body?

 

 

Not really the topic we're wanting to discuss, but here's my five cents:

 

Your acne is not caused by a Vitamin A deficiency so I don't recommend doing anything that requires guess work.

Just avoid Accutane and other toxic stuff and implement a relatively healthy diet while focusing on what you do have (i.e. health, family, wealth).

Don't know anything about your skin, but I still get spots ever now and then and every time I shave it really irritates my skin. Probably because Accutane got rid of the natural oils that should prevent this.

 

Your skin will likely improve with time.

 

 

I've had acne since wut...about...14. I'm a 24 female now. I don't think so, but that's just me because it's worse. I'm sorry it's not what you wanna talk about, but you guys did kind of put me off to Accutane, which is fine because it's probably not the best drug on the planet. At the very least I suppose, Accutane did get rid of your acne though, which is something I still have to live with pain wise and depression wise ( sometimes I don't eat because of my acne ) but I see there are worse things. I already have a pristine diet and what not but the effects of that have 'worn off.'

 

However, I kind of also want to find out how many of the people in this thread took high or low doses or multiple doses. I'm still researching, not necessarily to go on Accutane as I'm a bit too afraid of it, but I still want to know of other people's experiences so thanks for sharing. I dunno if this helps but my parents are health nuts and sent me this thingy called Dr. Christopher's Pancreas Formula and I use it now and again and it made me feel somewhat better. I'm not trying to advertise it, I dunno if it would help fix your problem with liver and other issues. There's just so many things out there that can help. But looking into parathyroid disease for some of you would be a good idea especially with the low D issue and I couldn't emphasis that enough. Your thyroid can be perfectly fine but your parathyroid is completely different.

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91
(@josephbuchignani)

Posted : 08/19/2012 6:52 am

Here is a theoretical mechanism for UDCA's broad capacity to reverse Accutane effects.

 

Accutane attacks epithelial cells:

 

 

Epithelium is one of the four basic types of animal tissue, along withconnective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation. In Greek "epi" means, "on, upon," and "thele" meaning "nipple".[1] Epithelial layers are avascular, so they must receive nourishment via diffusion of substances from the underlying connective tissue, through the basement membrane.[2][unreliable source?] Epithelia can also be organized into clusters of cells that function as exocrine and endocrine glands. Exocrine and endocrine epithelial cells are highly vascular.

 

UDCA reduces inflammation generated by the endoplasmic reticulum stress mechanisms in the epithelium:

 

 

Inflammatory bowel diseases (IBD) are chronically relapsing and immune-mediated disorders of the gastrointestinal tract. Endoplasmic reticulum (ER) stress mechanisms in the epithelium have been demonstrated to be implemented into the pathogenesis of intestinal inflammation. Chemical chaperones have been demonstrated to exhibit beneficial effects in various diseases associated with ER stress mechanisms by prohibiting the unfolded protein response (UPR). In a structure-function analysis, we tested the potential of the conjugated bile salt sodium tauroursodeoxycholate (TUDCA), naturally present in the small bowel, to resolve ER stress in intestinal epithelial cells. TUDCA efficiently inhibited the expression of UPR dependent genes like GRP78 triggered by the ER stressor tunicamycin in the small intestinal epithelial cell line Mode-K. TUDCA inhibited upstream signaling events in all three branches of the UPR cascade and diminished binding of UPR activated transcription factors to the grp78 promoter. A structure-function analysis revealed that UDCA but not its conjugation partner taurine, known as a chemical chaperone, is responsible for the inhibition of GRP78 induction and that UDCA is 10 times more effective than its taurine conjugate. This inhibitory effect was confirmed in a cell free assay, where TUDCA and UDCA but not taurine effectively inhibited the aggregation of thermally denatured BSA. We conclude that TUDCA and UDCA are potent anti-aggregants for the resolution of ER stress in intestinal epithelial cells and should be considered as a potential drug target to resolve ER stress mechanisms underlying the pathology of IBD.

 

This could explain

1: How Accutane seems to affect systems all throughout the body, in a weird undiscernable pattern

2: How UDCA could improve all affected systems

 

I have noticed darkened stool for the first time; previously mine were always pale. All symptoms seem to be gone (without changing diet), except when I don't get a good night's sleep. Then I have similar symptoms at a lower intensity. I am doubling my dose to 2g/d to see if I can make further gains. Withdrawal from UDCA was pretty hellish, worse than I was before I took it.

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26
(@maynerd)

Posted : 08/19/2012 10:55 pm

Looks like we need more people to scan their gallbladders... it makes sense if accutane was hiding and fermenting there then it breaks off randomly and re toxifies our system.

 

Has anyone with sexual sides noticed changes in their testicles? The problem with mine is they don't suck up into my body like they used to when I am cold/ doing physical activity/ having sex. Anyone know how to fix? I need my boys to be high and tight/

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MemberMember
12
(@user116745)

Posted : 08/20/2012 4:08 pm

Yeah.. Don't we all.

But from a spiritual point of view (and I'm hardly Gandhi) we shouldn't spend lots of time being angry and hateful against anyone, especially a bunch of faceless guys who made this drug.

Yepp, we'd all like to make them pay for what they've done to us and our bodies, but we can't.

We all need to work towards acceptance, in terms of accepting that we are where we are and bad things can happen.

We're very wise about health and medicine now, so at least we've learned something.

 

 

I agree with this completely. It is not worth it to use anger negatively, but instead, use it in a positive way to better our lives, and others. I know this, but am still practicing to do it all the time. Also, acceptance is a necessary step of recovery. We are beings that can be damaged and don't live forever. Everyone has to face this.

 

I sent the domain to Roche. Laws are laws. It was my mistake to by a copyrighted domain. I will have to be more clever next time.

 

A few nights ago, I was about to go to sleep, and realized something I need to share and emphasize on. It is the healing power of the sun, heat, and humidity for our body. For most of my life, I lived in Colorado, USA. It is a place with a dry climate, cold winters, and warm summers. And also was at elevation. While living there, I had to work very hard to get my body and skin moist again, the dryness was a constant challenge for my body.

 

During the summer of last year, I went to extremes to sweat. I put on 3 pears of sweat pants, 3 hoodies, 2 pairs of gloves, a winter hat, leg socks, etc. I would plug in my head phones with some fast electronic music, hop on my bike and go to a bike trail that was very long. I peddled as fast as I could. People gave me some looks for dressing the way I did in the middle of summer, but it did not matter. I regularly rode about 20 miles before returning home. I would then take off all the clothes and eat some watermelon. Eating that watermelon after sweating and working so hard gave me some of the most intense feelings I have ever experienced from eating food. Completely awesome. Anyway, it was very hard for me to sweat in this climate. I did not have problems sweating before Accutane in this climate. I am proud of what I did to fight against this problem.

 

In the winter of last year, I moved to Ohio, to live with my dad. Ohio is a place with cold winters and warm summers as well, but with one big difference. The humidity! It rains quite often here. It is a complete joy living in a place with water in the air. I worked outside this summer and the heat and humidity together with the sun shining helped everything in my body. It is much easier for me to sweat here. My joints move easier, I can flex stronger, I can breathe better, I sleep better, my eyes are wetter, my hair is stronger, etc, etc. The body works very well with heat and humidity. It makes sense. Rainforests are where the most abundance of life is found, and deserts are the opposite. The wet compared to the not wet.

 

Some words for thought!

 

 

 

Has anyone with sexual sides noticed changes in their testicles? The problem with mine is they don't suck up into my body like they used to when I am cold/ doing physical activity/ having sex. Anyone know how to fix?

 

 

After my tane treatement, my balls were cold and I couldn't get erections easily. I actually had an ultrasound done on my testies. They found nothing.

 

To fix it, simply, you have to become healthy again. Have a great diet, exercise, good sleep, positive mindset. Work hard at it everyday. Your blood will flow better and all your organs will work good again over time.

Quote
MemberMember
143
(@indigorush)

Posted : 08/21/2012 2:00 pm

 

Yeah.. Don't we all.

But from a spiritual point of view (and I'm hardly Gandhi) we shouldn't spend lots of time being angry and hateful against anyone, especially a bunch of faceless guys who made this drug.

Yepp, we'd all like to make them pay for what they've done to us and our bodies, but we can't.

We all need to work towards acceptance, in terms of accepting that we are where we are and bad things can happen.

We're very wise about health and medicine now, so at least we've learned something.

 

 

I agree with this completely. It is not worth it to use anger negatively, but instead, use it in a positive way to better our lives, and others. I know this, but am still practicing to do it all the time. Also, acceptance is a necessary step of recovery. We are beings that can be damaged and don't live forever. Everyone has to face this.

 

I sent the domain to Roche. Laws are laws. It was my mistake to by a copyrighted domain. I will have to be more clever next time.

 

A few nights ago, I was about to go to sleep, and realized something I need to share and emphasize on. It is the healing power of the sun, heat, and humidity for our body. For most of my life, I lived in Colorado, USA. It is a place with a dry climate, cold winters, and warm summers. And also was at elevation. While living there, I had to work very hard to get my body and skin moist again, the dryness was a constant challenge for my body.

 

During the summer of last year, I went to extremes to sweat. I put on 3 pears of sweat pants, 3 hoodies, 2 pairs of gloves, a winter hat, leg socks, etc. I would plug in my head phones with some fast electronic music, hop on my bike and go to a bike trail that was very long. I peddled as fast as I could. People gave me some looks for dressing the way I did in the middle of summer, but it did not matter. I regularly rode about 20 miles before returning home. I would then take off all the clothes and eat some watermelon. Eating that watermelon after sweating and working so hard gave me some of the most intense feelings I have ever experienced from eating food. Completely awesome. Anyway, it was very hard for me to sweat in this climate. I did not have problems sweating before Accutane in this climate. I am proud of what I did to fight against this problem.

 

In the winter of last year, I moved to Ohio, to live with my dad. Ohio is a place with cold winters and warm summers as well, but with one big difference. The humidity! It rains quite often here. It is a complete joy living in a place with water in the air. I worked outside this summer and the heat and humidity together with the sun shining helped everything in my body. It is much easier for me to sweat here. My joints move easier, I can flex stronger, I can breathe better, I sleep better, my eyes are wetter, my hair is stronger, etc, etc. The body works very well with heat and humidity. It makes sense. Rainforests are where the most abundance of life is found, and deserts are the opposite. The wet compared to the not wet.

 

Some words for thought!

 

 

 

Has anyone with sexual sides noticed changes in their testicles? The problem with mine is they don't suck up into my body like they used to when I am cold/ doing physical activity/ having sex. Anyone know how to fix?

 

 

After my tane treatement, my balls were cold and I couldn't get erections easily. I actually had an ultrasound done on my testies. They found nothing.

 

To fix it, simply, you have to become healthy again. Have a great diet, exercise, good sleep, positive mindset. Work hard at it everyday. Your blood will flow better and all your organs will work good again over time.

 

 

Can I make a request for you to make a video?

Dunno, would just be good to see that beard in action.

Haha.

Want to widen the Post-Accutane community a bit.

 

BAXYL and SAM-e - Been taking for 4 days and have seen no improvements.

Disappointed to be honest.

The guy I was speaking to about BAXYL said it worked instantly.

Does it hell! haha

And SAM-e was allegedly a fast-worker too.

Ah well.

That's the line drawn.

NO more supplements.

I'll use up what I have, but unless anything kicks in and starts working, I don't plan on buying any more.

Even Vitamin C powder, Vitamin D and stuff like that.

I just think it'd be better to have half a lemon in water each day, some fruit and sunshine (when possible, in England)

Tired of paying out £50 an order, + £20 import fee at times, and getting nothing in return.

Gonna take the pressure off myself and just eat better, relax more and spend money on things which guarantee no disappointments.

 

Turning my attention to having fun again.

Connor is an inspiration.

I think 'Where there's a will, there's a way' can be turned into 'Where there's a way, there's a will'.

It may not happen fast, but I believe our best hope of recovering our health is to trust in nature and not expect too much.

 

Saw Ted last night.. Good film. It's good to relax and watch a decent comedy.

I get tired easily, and I think that's a sign to just rest completely.

Sure, no can do whilst at work, but Saturday I was out at the beach with some friends and I stayed out all day because I didn't want to make an excuse to get away.

Ended up having a horrible headache (probably from too much Sunshine - everything in moderation) and felt knackered.

 

It's always good important to remember: Don't take yourself, or life, too seriously. We did nothing to earn a place on this earth, so everything good that happens in a bonus.

I'm also enjoying Super Mario on the 3DS :)

 

By the way, the hyaluronic acid creme I ordered (and mentioned) does seem very good, so maybe try that if you get dry/flaky skin.

 

The sweating thing though - I sweat far too easily, and excessively. That first became a problem while taking the drug... Exercise in hot weather makes me drip like a motherfucker! Not sure sweating really does much good where I'm sitting.

Quote
MemberMember
148
(@oli-girl)

Posted : 08/21/2012 9:47 pm

 

 

Yeah.. Don't we all.

But from a spiritual point of view (and I'm hardly Gandhi) we shouldn't spend lots of time being angry and hateful against anyone, especially a bunch of faceless guys who made this drug.

Yepp, we'd all like to make them pay for what they've done to us and our bodies, but we can't.

We all need to work towards acceptance, in terms of accepting that we are where we are and bad things can happen.

We're very wise about health and medicine now, so at least we've learned something.

 

 

I agree with this completely. It is not worth it to use anger negatively, but instead, use it in a positive way to better our lives, and others. I know this, but am still practicing to do it all the time. Also, acceptance is a necessary step of recovery. We are beings that can be damaged and don't live forever. Everyone has to face this.

 

I sent the domain to Roche. Laws are laws. It was my mistake to by a copyrighted domain. I will have to be more clever next time.

 

A few nights ago, I was about to go to sleep, and realized something I need to share and emphasize on. It is the healing power of the sun, heat, and humidity for our body. For most of my life, I lived in Colorado, USA. It is a place with a dry climate, cold winters, and warm summers. And also was at elevation. While living there, I had to work very hard to get my body and skin moist again, the dryness was a constant challenge for my body.

 

During the summer of last year, I went to extremes to sweat. I put on 3 pears of sweat pants, 3 hoodies, 2 pairs of gloves, a winter hat, leg socks, etc. I would plug in my head phones with some fast electronic music, hop on my bike and go to a bike trail that was very long. I peddled as fast as I could. People gave me some looks for dressing the way I did in the middle of summer, but it did not matter. I regularly rode about 20 miles before returning home. I would then take off all the clothes and eat some watermelon. Eating that watermelon after sweating and working so hard gave me some of the most intense feelings I have ever experienced from eating food. Completely awesome. Anyway, it was very hard for me to sweat in this climate. I did not have problems sweating before Accutane in this climate. I am proud of what I did to fight against this problem.

 

In the winter of last year, I moved to Ohio, to live with my dad. Ohio is a place with cold winters and warm summers as well, but with one big difference. The humidity! It rains quite often here. It is a complete joy living in a place with water in the air. I worked outside this summer and the heat and humidity together with the sun shining helped everything in my body. It is much easier for me to sweat here. My joints move easier, I can flex stronger, I can breathe better, I sleep better, my eyes are wetter, my hair is stronger, etc, etc. The body works very well with heat and humidity. It makes sense. Rainforests are where the most abundance of life is found, and deserts are the opposite. The wet compared to the not wet.

 

Some words for thought!

 

 

 

Has anyone with sexual sides noticed changes in their testicles? The problem with mine is they don't suck up into my body like they used to when I am cold/ doing physical activity/ having sex. Anyone know how to fix?

 

 

After my tane treatement, my balls were cold and I couldn't get erections easily. I actually had an ultrasound done on my testies. They found nothing.

 

To fix it, simply, you have to become healthy again. Have a great diet, exercise, good sleep, positive mindset. Work hard at it everyday. Your blood will flow better and all your organs will work good again over time.

 

 

Can I make a request for you to make a video?

Dunno, would just be good to see that beard in action.

Haha.

Want to widen the Post-Accutane community a bit.

 

BAXYL and SAM-e - Been taking for 4 days and have seen no improvements.

Disappointed to be honest.

The guy I was speaking to about BAXYL said it worked instantly.

Does it hell! haha

And SAM-e was allegedly a fast-worker too.

Ah well.

That's the line drawn.

NO more supplements.

I'll use up what I have, but unless anything kicks in and starts working, I don't plan on buying any more.

Even Vitamin C powder, Vitamin D and stuff like that.

I just think it'd be better to have half a lemon in water each day, some fruit and sunshine (when possible, in England)

Tired of paying out £50 an order, + £20 import fee at times, and getting nothing in return.

Gonna take the pressure off myself and just eat better, relax more and spend money on things which guarantee no disappointments.

 

Turning my attention to having fun again.

Connor is an inspiration.

I think 'Where there's a will, there's a way' can be turned into 'Where there's a way, there's a will'.

It may not happen fast, but I believe our best hope of recovering our health is to trust in nature and not expect too much.

 

Saw Ted last night.. Good film. It's good to relax and watch a decent comedy.

I get tired easily, and I think that's a sign to just rest completely.

Sure, no can do whilst at work, but Saturday I was out at the beach with some friends and I stayed out all day because I didn't want to make an excuse to get away.

Ended up having a horrible headache (probably from too much Sunshine - everything in moderation) and felt knackered.

 

It's always good important to remember: Don't take yourself, or life, too seriously. We did nothing to earn a place on this earth, so everything good that happens in a bonus.

I'm also enjoying Super Mario on the 3DS smile.png

 

By the way, the hyaluronic acid creme I ordered (and mentioned) does seem very good, so maybe try that if you get dry/flaky skin.

 

The sweating thing though - I sweat far too easily, and excessively. That first became a problem while taking the drug... Exercise in hot weather makes me drip like a motherfucker! Not sure sweating really does much good where I'm sitting.

 

 

You have to give supplements some time to see if they work...there is NO miracle in a few days :)

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MemberMember
12
(@user116745)

Posted : 08/21/2012 11:16 pm

Thank you again for the kind words Indigo. I do feel like an inspiration and want to inspire others in this thread.

 

I am glad you want to buy and eat more whole foods instead of supplements. Great!! You are doing good things. Keep the positive momentum rolling!

 

I want to see Ted! Read good reviews of it. And Mario! Hell yeah. I checked out a 3DS in store a few months ago and was so impressed with the screen. The 3D on it is awesome.

Quote
MemberMember
143
(@indigorush)

Posted : 08/22/2012 12:07 pm

Thank you again for the kind words Indigo. I do feel like an inspiration and want to inspire others in this thread.

 

I am glad you want to buy and eat more whole foods instead of supplements. Great!! You are doing good things. Keep the positive momentum rolling!

 

I want to see Ted! Read good reviews of it. And Mario! Hell yeah. I checked out a 3DS in store a few months ago and was so impressed with the screen. The 3D on it is awesome.

 

 

 

 

This guy is so good :)

Looking forward to the video Connor.

I'll link my Youtube viewers to it

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(@user116745)

Posted : 08/22/2012 7:33 pm

I have changed my mind on making a video, for the time being. The man in the video above explains very well the information I have been posting on this forum. Specifically about eating plants and exercising. He goes into more detail though, spiritually and scientifically. This quote from the video sums it up for anyone thinking a raw diet may work.

 

"I'm going to change you and get you to see things my way... Ahh screw it man. You wanna jump on this team? Try it out. Drink some wheat grass, go for a run, see if it works".

 

I have not been using the word raw when I talk about eating plants. It is what I am referring to though. I will say 'raw plants' from now on so I am more clear.

 

That guy has it down. His hair is oily. Skin is strong, good color. Strong veins. Etc. He is healthy.

 

I have been on about a 65% raw diet for the last few months. But it is time for me to go 100%.

 

I am kicking peanut butter and peanuts. It is roasted peanuts (the peanut butter uses roasted peanuts as well). Roasted peanuts are very dry, cooked, and slowing down my body. And peanut butter is much too concentrated, oily, and fattening. I will stick to just almonds now for nuts.

 

And I am going to stop eating meat, and fish, and eggs. Unless it is raw. Recently I have not been doing heavy exercise, so these high proteins foods aren't very useful for me anyway. Also, slaughterhouses are fucked up. Every time I eat an animal product it does not feel right. I imagine what has been done to the animal to give me that food. But I never cared enough to stop eating it. I want to only eat creatures that I have killed myself. It is the right way to me.

 

I am excited about this. I have never done a 100% raw diet. The time is now. I expect for my whole body to feel better!

 

YOU should try it too!!

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(@indigorush)

Posted : 08/23/2012 1:50 am

But I want to see the beard :(

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(@user116745)

Posted : 08/23/2012 2:12 am

Hahaha. Someday!! You should grow one, they are just the bees' knees. [Edited image out]

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(@dthtodrmtlgsts)

Posted : 08/23/2012 4:42 am

Stool samples came back today.. Nothing special except some blood. Not neccesseraly cause of concern she said on the phone.. Going to have a talk with doc on monday. Still hoping to get a methylcobalamin prescription as i have not gotten a hold of it jet.

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157
(@chico-esposito)

Posted : 08/23/2012 8:42 am

Here is a theoretical mechanism for UDCA's broad capacity to reverse Accutane effects.

 

Accutane attacks epithelial cells

 

 

Epithelium is one of the four basic types of animaltissue, along withconnective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation. In Greek "epi" means, "on, upon," and "thele" meaning "nipple".[1] Epithelial layers are avascular, so they must receive nourishment via diffusion of substances from the underlying connective tissue, through the basement membrane.[2][unreliable source?] Epithelia can also be organized into clusters of cells that function as exocrine and endocrine glands. Exocrine and endocrine epithelial cells are highly vascular.

 

UDCA reduces inflammation generated by the endoplasmic reticulum stress mechanisms in the epithelium:

 

 

Inflammatory bowel diseases (IBD) are chronically relapsing and immune-mediated disorders of the gastrointestinal tract. Endoplasmic reticulum (ER) stress mechanisms in the epithelium have been demonstrated to be implemented into the pathogenesis of intestinal inflammation. Chemical chaperones have been demonstrated to exhibit beneficial effects in various diseases associated with ER stress mechanisms by prohibiting the unfolded protein response (UPR). In a structure-function analysis, we tested the potential of the conjugated bile salt sodium tauroursodeoxycholate (TUDCA), naturally present in the small bowel, to resolve ER stress in intestinal epithelial cells. TUDCA efficiently inhibited the expression of UPR dependent genes like GRP78 triggered by the ER stressor tunicamycin in the small intestinal epithelial cell line Mode-K. TUDCA inhibited upstream signaling events in all three branches of the UPR cascade and diminished binding of UPR activated transcription factors to the grp78 promoter. A structure-function analysis revealed that UDCA but not its conjugation partner taurine, known as a chemical chaperone, is responsible for the inhibition of GRP78 induction and that UDCA is 10 times more effective than its taurine conjugate. This inhibitory effect was confirmed in a cell free assay, where TUDCA and UDCA but not taurine effectively inhibited the aggregation of thermally denatured BSA. We conclude that TUDCA and UDCA are potent anti-aggregants for the resolution of ER stress in intestinal epithelial cells and should be considered as a potential drug target to resolve ER stress mechanisms underlying the pathology of IBD.

 

This could explain

1: How Accutane seems to affect systems all throughout the body, in a weird undiscernable pattern

2: How UDCA could improve all affected systems

 

I have noticed darkened stool for the first time; previously mine were always pale. All symptoms seem to be gone (without changing diet), except when I don't get a good night's sleep. Then I have similar symptoms at a lower intensity. I am doubling my dose to 2g/d to see if I can make further gains. Withdrawal from UDCA was pretty hellish, worse than I was before I took it.

 

 

Thats very interesting, epithelial tissue makes up most of the skin and bowel. It's well known accutane binds to the skin cell receptors and increases skin cell division. The skin cell cycle is increased so instead of it taking 28 days for the new skin to be made in the dermis and brought up to the top of the epidermis. It takes much less time, sometimes just a couple of days. Hence people with post accutane side effects suffering from psoriasis or sebborheic dermatitis, which is simply a large increase in skin cell division causing a large build up of dead skin on the skins surface.

 

It's the accutane that causes this, in my case the 13 cis retinoic acid is still in my skin cell receptors causing this increase in skin cell differentiation, once it's replaced or removed the skin cell division will go back to a normal cycle. Thats why i know it's still in my body. Compounded by the fact that hypervitaminosis A caused by vitamin A derivatives can cause intrahepatic cholastasis, damages and sometimes stops bile flow, so fat soluble compounds like accutane cannot be removed in the bile. But it could well be UDCA / TUDCA's effect on inflammation thats also causing this.

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(@josephbuchignani)

Posted : 08/23/2012 9:55 am

People pursuing the adrenal/thyroid angle may be interested in this, which has a liver tie-in apparently: [Edited link out]

I find my energy satisfactory now except when I get God-hammered by cramps. Eating less seems to help. I'm starting Dr. Snow's full protocol to repair my intestinal lining. I'll also buy some additional digestive enzymes and bile salts for the lower tract.

Amazon's product reviews have some of the best quality health info anywhere. Really rather astounding. Too bad you can't search reviews.

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