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Repairing the long-term damage from Accutane

 
0
(@Anonymous)

Posted : 01/29/2018 3:39 pm

6 hours ago, Jens22 said:

Guys i think youre maybe overthinking it.
To my person: 23 years took accutane for about 1,5 years 20mg PER WEEK sometimes 40mgs per week!!
I stopped accutane 9 months ago. No erections in the morning no erections having sex or masturbating.
Just had 2 weeks in those 9 months since stopping it where everything worked fine, started with morning erection and followed by a lots of masturbating the following days.
And as fast as it has come it has gone... the next day...
havent had it now for about 3 months so wondering if it comes back...

My opinion is: Its just some problem with some hormone receptors or something and once they things luckily work right in our body for some days everything can be normal. i dont think there is something completeley destroyed by accutane... just blocked.

The first months i stopped accutane it felt liked i have no connection between head and dick but thats bullshit its still there... just some hormones must be right. by reading those forums everything gets worse...and if u contact roche or whatever brand this product makes it will not make your personal own problems better.

So lets stop typing that much and try to find some easy solution to the problem. cause i am sure there is
and it might come back overnight like it did 2 times for me.

i ve tried a lot of nutritional shit and nothing really worked... no doctor could help me so far as they just not listening or interested in the reason they all tried to give me some viagra and i tried it and it didnt work. also the skat test didnt work...

Is there anybody out there who solved his problem ? there are a lot of guys who recovered i am sure. just let me know how. and dont overthink the problem or make it too complicated. i read a lot in this thread here and it made me feel worse.

my skin doctor back then didnt tell me about this possibility and he said there will hardly be any side effects with 40 mgs per week. i think i took about 50mg/kg bodyweight.. so i weigh about 80kgs (think 175 pounds or so) and took about 3500mg isotretinoin.
Other side effects i have but i dont really mind.. sometimes bit nervous, a lot more sweating.. bit of dry lips but nothing severe!

If somebody knows about someone who solved is problem, who recovered let me know and let me know how!

try l-carnitine in high dose (<1gr)

after accutane I have high androgen level but incredible, i life with rare and weak morning erection. Carnitine helps androgen receptors, with l-carnitine I had the best erections in my life after accutane.
do not expect this is a cure, it's just a momentaneus solution

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(@dubya_b)

Posted : 01/29/2018 4:20 pm

On 1/28/2018 at 0:31 AM, Frage said:

@Perene

Yet alot of people have known these things for decades, tried treatments that have supposedly cured or helped others and had no success for them. Can't wait for that Baylor study to come out.

My sentiments exactly. It was recently pointed out on one of the PFS forums that the common link in nearly all of the PFS recovery stories was that they occurred within 6-12 months after one developed PFS. i.e: natural recoveries, not some contrived treatment.

There are many people quietly waiting for the Baylor study. Without it, we (sufferers of post-Accutane "PFS") have no hope at this point. Not much else to say or do.

.

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(@macleod)

Posted : 01/29/2018 4:25 pm

Been following Roche for years in the market, they always manage to turn at least 1-2% profit on a yearly basis for investors. They are always in the black and never in the red (Criminals). and itdoesn't look like they are going to ever lose in the near future... Rare breakthrough ofa new Autism drug by Roche.

https://seekingalpha.com/news/3325942-roches-balovaptan-breakthrough-therapy-u-s-autism?dr=1#email_link

I find it highly interesting since it has to do with vasopressin, which I have researched in the past, and put on my to-do list as far as checking levels and experimenting with supplementation. I recommend everyone (especially those with ED) do more research on vasopressin.

I often wonder if experimenting on human populations leads to new drug development and new breakthroughs. I'm pretty confident that they know the mechanisms of action of Accutane.

Anyways, I recommend a look at vasopressin and supplementation of Arginine, for those with suspected circulation issues (raynauds in my case) post Accutane. Who knows maybe someone with ED can get a doctor to supplement some vasopressin and maybe it works.

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(@colinboko)

Posted : 01/29/2018 5:26 pm

1 hour ago, Dubya_B said:
My sentiments exactly. It was recently pointed out on one of the PFS forums that the common link in nearly all of the PFS recovery stories was that they occurred within 6-12 months after one developed PFS. i.e: natural recoveries, not some contrived treatment.

There are many people quietly waiting for the Baylor study. Without it, we (sufferers of post-Accutane "PFS") have no hope at this point. Not much else to say or do.

.

This isnt entirely all that accurate...

There have been countless cases of people recovering with various types of hormone replacement therapies, dietary changes, liver/gut cleanses.. the whole works. So to say if you dont recover within 6-12 months after cessation of treatment, that you wont recover or have the ability to at least treat your symptoms is bogus. Just saying..

Some may say being on something to alleviate symptoms isnt really a cure but if I feel back to my normal self on certain medications thats good enough for me..

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(@truejustice)

Posted : 01/29/2018 7:26 pm

Given that theres a whole host of issues going on with many of us post tane, for sure there are things you can work on improvingeven if its 5-10 years with theseside effects.

I will say though being a 20 year sufferer, nothing has improved my systemic dryness, not the best water in the world, not Baxyl, no supplement has done a thing in that dept, so at this stage and Im happy to be proven wrong but Its Permanent Im sorry to say!!

Accutane certainly did its job with frying my sebaceous glands and I have no clue on how to fix it....

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(@perene)

Posted : 01/29/2018 8:22 pm

I visited a nutritionist today and so far he only prescribed (note: I go to the gym everyday) Whey Protein Concentrate, Creatine (5g/day), Fish Oil 1000 mg (3/day), and:

Fat-soluble vitamins:
D-3 (2000 UI) and E (200 UI). He said to take one pill/day.

Plus probiotics, 1/day. What he recommended can be seen here:
[Edited link out] and [Edited link out]

I am still waiting for my new diet, he also sent some general tips, but that was it, about vitamin B-6 he only mentioned this one:
https://www.ems.com.br/arquivos/produtos/bulas/bula_polivitaminico_do_complexo_b_2044_1562.pdf

And hinted that it won't work the same way other meds like Cabergoline do, but judging from what I've seenI thinkhe was not informed about this subject. He measured a few things and I fit in all normal parameters:
https://en.wikipedia.org/wiki/Body_fat_percentage

My health is perfectly fine (not counting this side effect).

I'll ask in the next days tomyendocrinologist if taking B-6 (50 mg, P5P) will help in any way with the high prolactin, or my only recourse is to take Cabergoline and similar meds. I advise anyone reading me to disregard studies like this one:

[Edited link out]

Which say nothing tried worked, because they do not post any thorough detail from the individuals tested, and since every person is different we can't say that taking B-6 in all cases of low libido caused by the Accutane treatment won't work. There's no data to back these allegations, and when I say THERE'S NO DATA I mean no one posted all possible blood tests like I did in this thread.

Note: I don't doubt that 2014 study is accurate when it says using dopamine agonists (+ more testosterone) didn't help with low libido. My complaint is that there's a serious lack of documented evidence.

Another thing I would like to ask is about these passages from that Dr. Pezzi book. In it he mentions this can be a reason for this side effect:

******
I think it interferes with the proper functioning of some sensory peripheral nerves, or their receptors, or the brains response to the nerve data, thus greatly distorting tactile fidelity (a subject I will discuss in detail later in this chapter). This disturbance of fidelity is not necessarily confined to the genitals; Accutane has been associated with a dysesthetic * tingling on nongenital skin, the course and intensity of which seems to parallel the unpleasant sexual hit your funny bone tingling. These dysesthesias may persist for a few seconds after the inciting stimulus is removed. If you lightly touch your skin, for example, the sensation usually ends when the contact ceases. In contrast, Accutane-induced dysesthesias may take seconds to fade away.

* A dysesthesia (dis-es-THEE-zee-uh) is an unpleasant abnormal sensation, whether spontaneous or evoked. Many authors and physicians use dysesthesia interchangeably with paresthesia, which is an abnormal sensation that is not unpleasant. Dictionaries often muddy the issue by defining paresthesia as a burning, prickling, itching, or tingling skin sensation most of which are unpleasant.

*
See a knowledgeable physician to exclude other causes of dysesthesias and reduced sensation. There are numerous possible causes, such as vitamin B 12 deficiency, multiple sclerosis, brain tumors, strokes, transient ischemic attacks (TIAs), arteriovenous malformations, transverse myelitis, encephalitis, trauma, and peripheral neuropathies secondary to diabetes, alcoholism, hypothyroidism, hereditary conditions (Charcot-Marie-Tooth disease, Denny-Brown's syndrome, familial amyloidotic
polyneuropathy), malignancy, uremia, connective tissue disorders (e.g., rheumatoid arthritis, systemic lupus erythematosus, polyarteritis nodosa, autoimmune vasculitis, systemic sclerosis, and Sjogren's syndrome), inflammation (acute idiopathic polyneuritis and chronic relapsing polyneuropathy), chronic overdosage of vitamin B 6 , some chemotherapy, heavy metal toxicity (e.g., lead, arsenic, or mercury), some industrial exposures (e.g., solvents), certain medications, sarcoidosis, porphyria,
Lyme disease, and leprosy. Believe it or not, but this is just the tip of the iceberg.

Physicians should keep in mind that it is possible to have symptoms of dysesthesias or paresthesias without measurable neurologic deficits of pain, touch, vibration, joint position, or thermal sensation.

- As a last resort, consider trying one of the drugs used to treat dysesthesias and paresthesias, such as carbamazepine (Tegretol ), mexiletine (Mexitil ), gabapentin (Neurontin ), and tricyclic antidepressants (e.g., imipramine [Tofranil ] and amitriptyline [Elavil ]). Neurologists believe that paresthesias and dysesthesias represent abnormal showers of neural impulses generated from abnormalities anywhere along the sensory pathway, from the peripheral nerves to the sensory cortex of the brain. The aforementioned drugs may reduce the excitability of neurons and therefore mitigate Accutane-induced dysesthesias, especially the unpleasant tingling that persists after skin contact. However, these drugs will not restore sexual sensitivity.

- Be patient. The dysesthesias tend to diminish in time, although it may take years. Your perception of sexual pleasure will likely increase, too, although it may not return to your pre-Accutane zenith. The elimination half-life (that is, the time it takes for half of an administered drug to be excreted) suggests that Accutane does not persist in the body for a long time. The drug may not stick around for long, but its effects do. It is as if Accutane flips some switches in the body. This is true for its intended effect (the long-term suppression of acne), and its sexual side effects.

Once flipped, those effects are permanent, or at least very long lasting.

Hence, you should think twice before using Accutane. There is no way to know in advance if your use of Accutane will trigger dysesthesias and reduced sensation. You may take it for a while without any problems, and then wake up with enough sensory abnormalities to make you wonder if your spinal cord was mashed in a vice while you slept. Being cheated out of lifes greatest pleasure is a terrible fate. Are you willing to take that risk?
*****

P.S. My vitamin B-12 levels are OK, too. I would be interested to check for the B-6 levels, though.

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(@colinboko)

Posted : 01/29/2018 8:33 pm

1 hour ago, TrueJustice said:

Given that theres a whole host of issues going on with many of us post tane, for sure there are things you can work on improvingeven if its 5-10 years with theseside effects.

I will say though being a 20 year sufferer, nothing has improved my systemic dryness, not the best water in the world, not Baxyl, no supplement has done a thing in that dept, so at this stage and Im happy to be proven wrong but Its Permanent Im sorry to say!!

Accutane certainly did its job with frying my sebaceous glands and I have no clue on how to fix it....

How dry are you?

Like skin wise?

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(@guitarman01)

Posted : 01/29/2018 9:00 pm

if anyone is looking for any tests and something you could possibly treat, Id look into full testing for antiphospholipid syndrome.
I have not seen anyone else had this tested post Accutane.

Manydrugshave been considered as possibly causing APS but only in a limited number of patients. To our knowledge this is the first case ofdrug-inducedAPS with complete disappearance of high titers of anti-2GP1 antibodies after minocycline withdrawal.Jun 7, 2017

Clinical manifestations can include headache and memory loss. Also they are linking some types of autonomic dysfunction with antiphospholipid syndrome as well.

You'd be looking at any titer of antiphospholipid antibodies and/or positive lupus anticoagulant.
The safest form of Treatment would consist of daily baby aspirin. (this might not be enough)
A person can obviously try this on their own for a few days and see how they respond to anticoagulation.

Im not going to be spending much time posting on here for now. This is still what I have in mind though,
microcirculatory dysfunction in organs such as lung, heart, liver, brain, kidney retina, pancreas, testis, rectum, spinal cord, muscles, sympathetic and parasympathetic ganglia, and nerves.

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(@frage)

Posted : 01/30/2018 12:51 am

Interesting, I actually have the purplish skin condition I see in the pictures of antiphospholipid syndrome. However I have had it my whole life. I think it has got worse though.

Also a story for anyone who's interested: I just got back from the hospital the other day, checked into the emergency room with severe abdominal pain and bloating. By far the worst physical pain I've had in my entire life. Doctor says it was viral gastroenteritis, knowing post accutanes association with ibs though, I am definitely worried that this might mark the start of another chronic symptom. Only information I got back from the emergency room doc was that I had a very full stomach, very inflamed small intestine, and slightly elevated white blood cell count.

Something else, I have found the opioid pain medications I was prescribed have been very effective at alleviating alot of my mental sides. It has been over 24 hours since I took my last hydrocodone, and while the pain relieving effects seem to have warn off, I still am having things like my tinnitus, depression, anhedonia, poor night vision, etc relieved.

I'm wondering if this has to do with allopregnanolone. A guy named Bloom over on the raypeat forum theorizes that these effects from opioids are from there effect on up-regulating the 5ar1 enzyme, thus higher allo levels. He also says this isn't a great longterm solution, which is a little obvious. I'm kinda just talking out loud now so I'll leave it at that.

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(@truejustice)

Posted : 01/30/2018 5:28 am

8 hours ago, Colinboko said:
How dry are you?

Like skin wise?

Extremely dry!!

You dont have dry thin hair post tane? You dont have dry eyes and dry face too?

For me, nomoisture in skin especially face and yet I sweat profusely post tane? Cant explain that....
All my sebaceous glands are probably dried up and skin is very thin - many have reported this I believe!!

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(@macleod)

Posted : 01/30/2018 6:14 am

That quote from Pezzi up there is quite ground breaking for me since I myself experienced a transient ischemic attack mere weeks after my last accutane pill, shortly after smoking a joint one night (which was normal routine for me after a healthy active day ofsports and school, never had any issues). I went from 20 years of health(only seeing a doctor maybe a handful of times, usually for a flu)to a seemingly overnight change. I experienced all of that paresthesia he talks about throughout my nerves. It was immediately after that TIA that my crash occurred, hair falling out, tinnitus, vision issues, night vision diminished, joints and tendons cracking, etc. etc.

the anhedonia set in shortly after. I had been turning 21 around that time and after not seeing immediate success consultingdoctors, or having this newlyinformed forum around, I self medicated for years with alcohol trying to figure outexactly what happened.

i eventually took charge of my health and have been seeing 1-2% improvements a year. Obviously side effects remain (night vision, depression) but I feel my nervous system, anxiety, skeletal system has caught up to speed (although never like it used to be).

Anyways, that Pezzi guy knows his stuff and is spoton. All of our side effects differ but are also way too coincidental in some regards. I think Accutane affects the brain, I think we are close to finding out where, and I think we will find a solution either on our own or with help hopefully one day.

I try to tell myself I am healthy, but when you go from 20 years of a perfect life (health wise) to falling asleep everynight feeling your teeth chatter from your newly found hypertension, to your ear blaring with a high pitched whistle 24/7, neck, face, and fingers twitching as you fall asleep, you realize the power of this drug and how its more so than just Gut flora/digestive causes. It's more than likely systemic (neurology, endocrinology, skeletal, muscular, gastro, etc.)

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(@colinboko)

Posted : 01/30/2018 1:04 pm

7 hours ago, TrueJustice said:
Extremely dry!!

You dont have dry thin hair post tane? You dont have dry eyes and dry face too?

For me, nomoisture in skin especially face and yet I sweat profusely post tane? Cant explain that....
All my sebaceous glands are probably dried up and skin is very thin - many have reported this I believe!!

My skin is normal now. Like not too oily and not too dry. Just kind of like a normal person who doesnt deal with acne. I dont need to use a moisturizer ever. My hair texture changed which I think makes it look dry because I definitely have some form of telogen effluvium. I have shedding hair all over. But heres the catch; my chest and facial hair have always been a different texture/color than my arm and leg hair even before tane. My arm and leg hair pull out very easily just like my head hair but my chest and beard dont shed at all even when pulled. Which makes me think I still have some form of sensitivity to my receptors because I can still grow chest/facial hair that doesnt fall out. But I definitely have telogen effluvium body wide (minus chest/beard hair). All the hair that comes out has a white bulb and grows back EXTREEMEEELY slow. Which in result makes my hair look thin because not enough of it is in the growing stage.

As for dry eyes, I feel like theyre definitely drier but I wouldnt say the gland is destroyed. I can still wear contacts for a decent amount of time. Obviously later at night they bother me but that has always been the case even pre tane. I think my problem is extremely hormonal related in nature. Something lowered or heightened, put my body in shock (causing the telogen effluvium and all my other symptoms) and just never reset. So now Im just trying to get as many tests done as possible.

In all honesty, I relate more to women going through pregnancy and girls on birth control (symptom wise) than I do with some people on this forum lol.

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(@perene)

Posted : 01/30/2018 3:54 pm

For the record, here's what I found out just now: the max intake for Vitamin B-6, suggested to treat high prolactin instead of the expensive (and needed for years with a chance of the results being scrapped after interruption of treatment) Cabergoline and similar drugs.

(and this one was pointed as the best choice/most effective in treating the high prolactin):

- Pyridoxal 5'-phosphate (PLP), the metabolically active form (sold as P-5-P vitamin supplement)

It's not even 50 mg, but 25 mg/day. This PDF explains that thoroughly:
http://www.efsa.europa.eu/sites/default/files/efsa_rep/blobserver_assets/ndatolerableuil.pdf

http://www.drorestesg.com/blog/are-you-overdosing-on-vitamin-b6- (check this one, too)

I was discouraged after reading all this to try 50-200 mg. I think that contrary to the previous links I posted there's a chance of this supplement (at high doses) introduce new health issues, and opting for25 mg/day will not produce the same results, but it's a risk I am willing to take.

I converted the 2000 IU from the vitamin D prescribed by the nutritionist and noticed it fits the max intake ALSO RECOMMENDED from that PDF (for adults):

50 ug/day = exactly 2000 IU

For vitamin E the PDF apparently says 270 mg/day for adults (rounded to 300). 200 IU as prescribed is equivalent to 134 or 90 mg.

Vitamin-E is mentioned to be helpful in this regard just like B-6.
https://raypeatforum.com/community/threads/vitamin-a-is-dopaminergic-and-reduces-prolactin-in-humans.6053/

As for vitamin D, Greg made some great comments in this podcast episode, but since the Sun will hit directly my face I'll continue using, to prevent my skin from aging faster. I know that it's only a few minutes every day that I expose myself, still...

I'll sunbathe in the shade every morning (between 9am and 12pm, the only moment of the day when this can work), without any protection, to compensate for that, a few minutes. So with the supplement and this idea I predict my testosterone levels will be in the 400's again. And tomorrow I'll see if more blood tests can be done to add them to this investigation.

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(@truejustice)

Posted : 01/30/2018 4:35 pm

I like the combination there Perene.

If I didnt know any better it sounds like your nutritionist is combating any Vit A excess you have - E and D combo would hopefully control any Vit A overload.

At the moment Im just taking the Activated B vitamin daily, before I rush out to buy B6 Im just going to use up what I already have!!

Pls keep us posted on how you feel with your current routine - in particular the B6 experimenting

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(@frage)

Posted : 01/30/2018 9:04 pm

Hey, so anyone have stomach issues where it seems like food just doesn't move through your system? Something like gastroparesis? I haven't ate in 2 days, yet my intestines still feel extremely full. It feels like the food I ate days ago is just sitting in my digestive track, hardly moving. I have found a few of the pfs boys having the same problem. It seems the onset of this issue marked a point of worsening of symptoms and continued gut issues. In fact, I have already read one story where a guy had other organ failures after this symptom (that eventually killed him), and another where someone offed himself after getting this symptom (although he had several other debilitating symptoms). This is very disheartening. However, I do remember hearing some on hear who have gut issues. Is this relativity normal with this condition? Any bandaids for it? I got weight to spare but I can only not eat for so long you know. I hope I'm not getting myself all scrambled over this but its seeming like it could be relatively deadly.

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(@truejustice)

Posted : 01/30/2018 9:50 pm

47 minutes ago, Frage said:

Hey, so anyone have stomach issues where it seems like food just doesn't move through your system? Something like gastroparesis? I haven't ate in 2 days, yet my intestines still feel extremely full. It feels like the food I ate days ago is just sitting in my digestive track, hardly moving. I have found a few of the pfs boys having the same problem. It seems the onset of this issue marked a point of worsening of symptoms and continued gut issues. In fact, I have already read one story where a guy had other organ failures after this symptom (that eventually killed him), and another where someone offed himself after getting this symptom (although he had several other debilitating symptoms). This is very disheartening. However, I do remember hearing some on hear who have gut issues. Is this relativity normal with this condition? Any bandaids for it? I got weight to spare but I can only not eat for so long you know. I hope I'm not getting myself all scrambled over this but its seeming like it could be relatively deadly.

Any bandaids for it??

yes, go see a Gastroenterologist, tell them you took Accutane and you suspect its messed up your gut health.

Tell them while you suspect theres nothing sinister going on ( Yet ) youd like to know what to do to improve your health!!?

Ask them, other than the usual offering of probiotics, what else is needed to fix gut?

Do this and then report back on forum.
well collect the data/response.

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(@frage)

Posted : 01/30/2018 10:42 pm

Yeah, bandaids.Thats almost all I'm in search of at the moment. Safe supplements and medications that make life a bit better while research continues on this disease. I am sure I will be seeing a doctor or two regarding this in the near future. Yet it has been my experience that most doctors are nearly useless when it comes to even treating the symptoms of our condition. I was hoping someone had kinda already been there done that on this topic and had a suggestion or two. LDN? Dopamine blockers? Part of me has a feeling its going to be hard finding a doctor who might have some good insight into these gastrointestinal problems and accutane.

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1803
(@guitarman01)

Posted : 01/30/2018 11:45 pm

2 hours ago, Frage said:

Hey, so anyone have stomach issues where it seems like food just doesn't move through your system? Something like gastroparesis? I haven't ate in 2 days, yet my intestines still feel extremely full. It feels like the food I ate days ago is just sitting in my digestive track, hardly moving. I have found a few of the pfs boys having the same problem. It seems the onset of this issue marked a point of worsening of symptoms and continued gut issues. In fact, I have already read one story where a guy had other organ failures after this symptom (that eventually killed him), and another where someone offed himself after getting this symptom (although he had several other debilitating symptoms). This is very disheartening. However, I do remember hearing some on hear who have gut issues. Is this relativity normal with this condition? Any bandaids for it? I got weight to spare but I can only not eat for so long you know. I hope I'm not getting myself all scrambled over this but its seeming like it could be relatively deadly.

who are these cases you mentioned? Do you have any links?
The acetylcholine ganglionic neuronal antibody is also something I tested positive for.
You can google and see how this can relate to gastric emptying.
Yes it seems like weak muscles and/or nervous system dysfunction can cause this.
Possibly lack of good blood flow to organs as well? When you talk about organ failure this comes to mind. sort of like what can happen with Lupus.

How vascular disease activates autoimmune disorders

Date:
January 9, 2014
Source:
Cell Press
Summary:
The hardening of the arteries, called atherosclerosis, that can lead to heart attack. It has also been linked to autoimmune disorders, but to date it has not been clear why these diseases are related. A new study reveals that a molecule that causes atherosclerosis also activates T cells, causing clinical symptoms of autoimmune disease to worsen in mice. The findings shed light on the link between autoimmunity and atherosclerosis, opening new avenues for the treatment of autoimmune disorders.
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(@mariovitali)

Posted : 01/31/2018 12:00 am

@guitarman01 @tanedout @TrueJustice

New Fibroscan of ME/CFS Patient with moderate to severe Fibrosis (f2 to f3).

Please check your Liver with a Fibroscan test.

stellazos-annot.jpg

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70
(@whackutane)

Posted : 01/31/2018 12:43 am

3 hours ago, Frage said:

Hey, so anyone have stomach issues where it seems like food just doesn't move through your system? Something like gastroparesis? I haven't ate in 2 days, yet my intestines still feel extremely full. It feels like the food I ate days ago is just sitting in my digestive track, hardly moving. I have found a few of the pfs boys having the same problem. It seems the onset of this issue marked a point of worsening of symptoms and continued gut issues. In fact, I have already read one story where a guy had other organ failures after this symptom (that eventually killed him), and another where someone offed himself after getting this symptom (although he had several other debilitating symptoms). This is very disheartening. However, I do remember hearing some on hear who have gut issues. Is this relativity normal with this condition? Any bandaids for it? I got weight to spare but I can only not eat for so long you know. I hope I'm not getting myself all scrambled over this but its seeming like it could be relatively deadly.

How recently have you taken accutane? Possible blocked bilary ducts? Have your bilirubin checked.

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(@truejustice)

Posted : 01/31/2018 12:45 am

Thanks for posting Mariovitali

Can I ask what the follow up was though??

what next for this patient - do you know?

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15
(@frage)

Posted : 01/31/2018 1:48 am

@guitarman01
The second guy I mention went by the name of quantumfaith over on solvepfs. [Edited link out]
The first guy I couldn't find where I read it. I could be misremembering because I know I thought I read that a long time ago.
Found out the administrator of propeciahelp, mew, had a case of gastroenteritis. Although, his experience was much different from mine.
http://www.propeciahelp.com/forum/viewtopic.php?f=1&t=10145
I need to calm myself down and wait and see.
Edit:
@Iamme.
year post tane

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(@jens22)

Posted : 01/31/2018 3:15 am

On 29.1.2018 at 11:26 PM, Colinboko said:
This isnt entirely all that accurate...

There have been countless cases of people recovering with various types of hormone replacement therapies, dietary changes, liver/gut cleanses.. the whole works. So to say if you dont recover within 6-12 months after cessation of treatment, that you wont recover or have the ability to at least treat your symptoms is bogus. Just saying..

Some may say being on something to alleviate symptoms isnt really a cure but if I feel back to my normal self on certain medications thats good enough for me..

So what medications u take ? and do you get morning erections again ?

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(@perene)

Posted : 01/31/2018 12:51 pm

I did more blood tests and already have some results:

[Edited link out]

Vitamin D and prolactin were measured again, for the 4th time. This time I saw something interesting: august and november = 25, january 28, but today it was 20.54 ng/mL. This is the first time the values changed.

That means prolactin levels can be lower in ideal conditions, they are higher when someone is under stress for example, and with all these changes I am going to make I am very optimistic this can be achieved. For a man normal levels are below 10.

Vitamin D now has risen to 44.5 ng/mL. That's great, because supplementing 2000 IU/day and spending some time in the shade (between 9am and 12pm) will elevate that number and help with testosterone as well. Vitamin D is crucial for it.

And for the 1st time progesterone, estradiol and DHEA-S (still waiting results from the latter). DHT I'll try to do next week. What's interesting is that the progesterone result was 0.9 ng/mL, and the lab ranges are:

>>>>> For men: lower than 0.1 - 0.2 <<<<<<<<

And Estradiol (E2): 18.00 pg/mL. Lab ranges are 11 - 144 pg/mL (for men).

I read here the following about high progesterone:

*****
Progesterone is the single most detrimental hormone to a man's libido. As a matter of fact, 80-90% of all erectile dysfunctions are contributed to this hormone being high..
*****

Is this further confirmation of this side effect of low libido from Accutane?

P.S. According to this source 0.9 for progesterone would be in the normal range:
http://www.peaktestosterone.com/Normal_Progesterone_Levels_Men.aspx

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Turko, Turko and Turko reacted
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(@flynn)

Posted : 01/31/2018 1:13 pm

Has anyone else on this forum with accutane induced sexual problems, had their progesterone measured after accutane? If so, what level was it?

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