Another poster said its given me the skin I have always dreamed of until the severe lower back pain kicked in years later , me lol. Btw I still have mild acne the magic pill did nothing for me , I couldntcare less about Acne anyways. Getting rid of my severe lowerback pain was way more important and I did without drugs 0 they only mask symptoms anyways and cause more problems down the road.

The ironic thing IS the severe lower back pain was caused by another drug and they offer you more drugs ha thats the system I tell you theres hardly anyone healthy left these days .

8 hours ago, ScarRight said:

You're right, this is still used. But they're studies out there showing my low dose regime is just as effective. It has cleared my skin and I have stopped getting breakouts. My dermatologist said this will be the way of the future and the higher doses are slowly going out of style.

Hey people on this forum said my low dose regime was silly and too low and I should get a second opinion. I actually did ask my dermatologist after three months should I increase my dose to 20mg? He simply said no, it will make no difference to your acne.

My derm is an older man too. But he follows current research and trends and does care about patient safety.

We don't know how the drug works at all, I don't think it's safe in any dose at all... we don't even know what the heck it exactly is.

For many people low dose works well though. If you really are so such a severe case, and nothing else works, then I'd say take low dose as well.

Some people start on 120mg, even more.

Did anyone take a look at the stats at all?

7 minutes ago, hatetane said:

Did anyone take a look at the stats at all?

They don't help. Most people don't report effects, because it is very tough to report, sometimes they don't trust you it's from tane...

8 hours ago, sirhc30 said:

Fatigue
Muscle Pain
Anxiety
Visual Snow/After Images/Double Images
IBS
Dry Skin
Dry Eyes/inflamed eyes

The symptoms get better very slowly. I took accutane 11 years ago...

The chances for a young person to develop all these, is literally virtually nil if not on this extremely dangerous drug.

People should think about quality of next 60+ years they have, not just 10 acne years. Derms don't accentuate long term effects.

2 minutes ago, fiksi said:

They don't help. Most people don't report effects, because it is very tough to report, sometimes they don't trust you it's from tane...

It's not that difficult to report.
Nothing will ever be done until we have proper data.
43 cases of erectile dysfunction reported to MHRA - do you believe this is realistic?

So no one even took at look at all the sides that people HAVE reported!

13 minutes ago, hatetane said:

It's not that difficult to report.
Nothing will ever be done until we have proper data.
43 cases of erectile dysfunction reported to MHRA - do you believe this is realistic?

So no one even took at look at all the sides that people HAVE reported!

But often doctors don't trust people. ED is probably far more spread, it's just it's hard to talk about.

I will be doing more tests, and looking to report. I have had a severe reaction, including extreme muscle weakness, pain in all muscles, ataxia, dizzyness, headache, joint pain, brain fog. I also have some muscle twitching.

It's getting better now, but it's only few weeks since I stopped. I am now like an old dying man, but improving.

1 minute ago, fiksi said:

But often doctors don't trust people. ED is probably far more spread, it's just it's hard to talk about.

I will be doing more tests, and looking to report.

Thank you and yes I understand that.

But that is why all the Vets here shouls be encouraging everyone to report their sides instead of leaving for 20 years or more.
Would you still have taken accutane if you knew there was a chance that you woulld get incurable sexual peoblems?

Everyone who didn't report their side effects prior to you taking it is as guilty as the regulators and prescribers!

Did you take a look at this?

https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000285965613.zip&agency=MHRA

1 minute ago, hatetane said:

Thank you and yes I understand that.

But that is why all the Vets here shouls be encouraging everyone to report their sides instead of leaving for 20 years or more.
Would you still have taken accutane if you knew there was a chance that you woulld get incurable sexual peoblems?

Everyone who didn't report their side effects prior to you taking it is as guilty as the regulators and prescribers!

Did you take a look at this?

https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000285965613.zip&agency=MHRA

I did not develop ED(not yet) but my erections might be weaker.

There is no chance I would have taken it if this was honestly listed, even as minor chance.

1 minute ago, fiksi said:

I did not develop ED(not yet) but my erections might be weaker.

There is no chance I would have taken it if this was honestly listed, even as minor chance.

Exactly my point.
I am very pleased for you that you escaped this side effect at least.
No libido issues?

Did you know that a young man stabbed his girlfriend to death whilst he was on accutane and stated this in his defence.
There was no data to fall back on so that girl lost her life and the young man has been left to rot in prison.
We have young men committing suicide, flying their planes into buildings, stabbing their doctors and driving their cars into hospital buildings.

When I asked MHRA why accutane is not listed an a psychotropic there reply was that because that is not it's intended use they don't have to list it as such.
Would you have taked accutane if you knew it could actually alter your brain.

Don't you think that everyone has the right to know this?
I believe many people are capable of committing crimes whilst they are on accutane - I just don't think it has fully come to light yet.

It's my understanding many of the mass shooting situations that occur in the US is a result of psychotropic drugs.

Accutane causes psychotic episodes in some - this is fact

https://www.cbsnews.com/news/suicide-pilots-mom-blames-accutane/

https://www.steadyhealth.com/topics/mental-changes-with-accutane

http://mentalhealthdaily.com/2015/04/30/drug-induced-psychosis/

[Edited link out]

https://www.cbsnews.com/news/accutane-killed-my-son/

http://www.dailymail.co.uk/news/article-2367075/Healthy-footballer-James-Sillcock-26-taking-acne-drug-RoAccutane-killed-mental-health-problems.html (member of this forum)

There is no monitoring of these cases.

PRAC are currently reviewing the effects of accutane on depression etc and that is why you should all be emailing them your story.

PM me if you want the email address.

On 1/11/2018 at 6:43 PM, hatetane said:

https://www.cbsnews.com/news/suicide-pilots-mom-blames-accutane/

https://www.steadyhealth.com/topics/mental-changes-with-accutane

http://mentalhealthdaily.com/2015/04/30/drug-induced-psychosis/

[Edited link out]

https://www.cbsnews.com/news/accutane-killed-my-son/

http://www.dailymail.co.uk/news/article-2367075/Healthy-footballer-James-Sillcock-26-taking-acne-drug-RoAccutane-killed-mental-health-problems.html (member of this forum)

There is no monitoring of these cases.

PRAC are currently reviewing the effects of accutane on depression etc and that is why you should all be emailing them your story.

PM me if you want the email address.

It's already been shown accutane can cause/worsen depression... by rechallenge as well. In this, there is also brain fog and more.

I've read some recovery stories and the stories all have some similarities. I will now test some things, including progesterone but other stuff as well.

I will not read on here, because I feel much better, if I live my life normally and don't deal with Accutane side effects every day.

42 minutes ago, sirhc30 said:

I've read some recovery stories and the stories all have some similarities. I will now test some things, including progesterone but other stuff as well.

I will not read on here, because I feel much better, if I live my life normally and don't deal with Accutane side effects every day.

I will be back in a few weeks / months and will tell if it worked.

Very good idea. Fasting, a health diet and exercise will give you a good foundation to build upon - I hope you include these in your regime.
Please report your side effects to
https://yellowcard.mhra.gov.uk/

Please keep in touch and good luck.

13 hours ago, ScarRight said:

Oh wow, calling me a punk.

Um.. This is my second time on Accutane. The first regime was over ten years ago. There were no long term side effects. They all stopped when ceasing the drug.

I only have dry lips. I'm sure that would stop too.

Care to provide any actual statistics? Quoting Emma Stine, a celebrity, doesn't really count? Any peer reviewed studies?

As an academic, when you need to call people things like 'punk' you generally know they have a weak argument on offer.

I did say I am sorry to hear your body reacted bad to Accutane. However, most patients, under the care of their dermatologist, have no long time side effects.

Going up to 80mg on your second month, after starting on 40mg, is extremely high. Normally it is a much slower build up than that.

Keeping in mind also I'm on 10mg a day. My derm will never go higher. I actually have a dermatologist who respects the power of the drug. I would never get to 14000mg when I finish hopefully by July. More like 3600-4000mg

Im still suffering from the the sides 7.5 years after 10mg/day for 30 days, but people have crashed after a single pill. Same with pfs.

You're very naive if you think you're fine 'under the care' of a dermatologist, we all thought that. Derms aren't magicians, they're just paid to prescribe the stuff which is (currently, but on borrowed time) legal and reassure you that it'll all be fine. If the side effects were your fingers falling off then it would be easy to see if there were issues, but as the most common major issue is chemical castration they can't see that & most won't tell them.

1 minute ago, tanedout said:

Im still suffering from the the sides 7.5 years after 10mg/day for 30 days, but people have crashed after a single pill. Same with pfs.

You're very naive if you think you're fine 'under the care' of a dermatologist, we all thought that. Derms aren't magicians, they're just paid to prescribe the stuff which is (currently, but on borrowed time) legal and reassure you that it'll all be fine. If the side effects were your fingers falling off then it would be easy to see if there were issues, but as the most common major issue is chemical castration they can't see that & most won't tell them.

Derms tend to play down effects, or merely focus on "you will have dry mouth" etc.

We weren't properly warned of some things, and indeed, even tane manual is being updated.

17 minutes ago, tanedout said:

Im still suffering from the the sides 7.5 years after 10mg/day for 30 days, but people have crashed after a single pill. Same with pfs.

You're very naive if you think you're fine 'under the care' of a dermatologist, we all thought that. Derms aren't magicians, they're just paid to prescribe the stuff which is (currently, but on borrowed time) legal and reassure you that it'll all be fine. If the side effects were your fingers falling off then it would be easy to see if there were issues, but as the most common major issue is chemical castration they can't see that & most won't tell them.

Chemical castration sounds about right my heartgoes out to all affected , I got lucky no sexual issues but many are not so lucky .

3 minutes ago, Gladiatoro said:

Chemical castration sounds about right my heartgoes out to all affected , I got lucky no sexual issues but many are not so lucky .

The problem is, one can't predict which side effect and when it comes about. Tane affects cell division, death etc. in very fundamental way... means affects every organ. Since our metabolisation rate is also different, you can develop a host of effects. It may be one, more, or many. It may be now, later, or year after tane.

1 hour ago, hatetane said:

Very good idea. Fasting, a health diet and exercise will give you a good foundation to build upon - I hope you include these in your regime.
Please report your side effects to
https://yellowcard.mhra.gov.uk/

Please keep in touch and good luck.

I think it's a big puzzle and exercises are a big piece of the puzzle, but only doing exercises does not work, just as other things alone do not work.

Can't report my side effects, because I'm not from UK and my english is not as well. Are the reports anonymously?

I see why people take isotretinoin , severe acne is hard on a person BUT handing it out like candy is a cruel joke on kids and young adults . Some people run to a derm with a few red spots FOOLS . In this world we are all supposed to be perfect things we see on tv , but it doesn't work like that , health is WAY more important vs looks way more in the end it's all you really have , money won't help you if your not healthy not a bit.

57 minutes ago, Gladiatoro said:

I see why people take isotretinoin , severe acne is hard on a person BUT handing it out like candy is a cruel joke on kids and young adults . Some people run to a derm with a few red spots FOOLS . In this world we are all supposed to be perfect things we see on tv , but it doesn't work like that , health is WAY more important vs looks way more in the end it's all you really have , money won't help you if your not healthy not a bit.

It seems so obvious now that you shouldn't trust doctors!
How many people look at the PIL when they are prescribed steroids for a chest infection or a statin to lower cholesterol?
How many people research metformin for diabetes or a SSRI for depression?
Who has ever read the PIL before taking an antibiotics or before being vaccinated?
How many women read the PIL before taking birth control?
How many people have read the PIL for Aspirin, paracetamol or ibuprofen?

How many people have been told to ignore the PIL by their care givers because it is unnecessarily extensive?

Anyone seen the recent reports that say that Ibuprofen causes men to become infertile?

We are all beating ourselves up for our stupidity but we should be able to trust doctors and all health care givers.
We should be able to trust the regulators to protect us from pharmaceutical companies.

I can honestly say I always trusted doctors before, just like millions of people around the world.

Now I know better, but at what cost?
My son will suffer for the rest of his life because I trusted doctors and was totally ignorant.
You guys are all suffering because you trusted doctors.

So did we commit a crime worthy of this punishment?

We have been treated worse that peadofiles in prisons or mental health institutions.
I don't know much about the law but I don't believe that they are allowed to chemically castrate these men.
But the whole health community are committing these crimes daily to very young innocent adolescents.

Just look at what the government is doing with their vaccination programs!

What is the world coming to and when will this madness end.

34 minutes ago, hatetane said:

It seems so obvious now that you shouldn't trust doctors!
How many people look at the PIL when they are prescribed steroids for a chest infection or a statin to lower cholesterol?
How many people research metformin for diabetes or a SSRI for depression?
Who has ever read the PIL before taking an antibiotics or before being vaccinated?
How many women read the PIL before taking birth control?
How many people have read the PIL for Aspirin, paracetamol or ibuprofen?

How many people have been told to ignore the PIL by their care givers because it is unnecessarily extensive?

Anyone seen the recent reports that say that Ibuprofen causes men to become infertile?

We are all beating ourselves up for our stupidity but we should be able to trust doctors and all health care givers.
We should be able to trust the regulators to protect us from pharmaceutical companies.

I can honestly say I always trusted doctors before, just like millions of people around the world.

Now I know better, but at what cost?
My son will suffer for the rest of his life because I trusted doctors and was totally ignorant.
You guys are all suffering because you trusted doctors.

So did we commit a crime worthy of this punishment?

We have been treated worse that peadofiles in prisons or mental health institutions.
I don't know much about the law but I don't believe that they are allowed to chemically castrate these men.
But the whole health community are committing these crimes daily to very young innocent adolescents.

Just look at what the government is doing with their vaccination programs!

What is the world coming to and when will this madness end.

Excellent comment go to whale. To you will learn a lot. We are being lied to constantly also look into dr Stefan Lankas work he is a genius.

After decades of intense data research I would say anything 200 years or newer in medicine IS detrimental to the human body FACT.

I once read about a woman with severe acne and she controlled it with salt baths never took isotretinoin, there are alternatives for acne , but dont take salt baths after tan exposure trust me on this . Our skin is permanently messed up .

This is madness ends when people wake up to the truth , its happening as we speak.

On 1/10/2018 at 2:02 AM, mariovitali said:

Which of course can be prevented / reversed with K2 :

isotretinoin is highly lipophilic. Vitamin k2 is highly lipophilic (even more so than vitamin k1)
When you look at how isotretinoin was administered, it was once or twice a day with a meal to increase absorption.
The isotretinoin capsule used oil as a carrier(soy)
vitamin k2 should be in oil soluble form.
I've seen a patent where they are saying preferred range for treatment are doses up to 1000 mcg mk7.
This would be way too much for most people initially.
The bare minimum (and possibly maximum) dose should hover around 360 mcg, this has been looked at in long term studies as being safe and a effective dosage for close to optimal activation of matrix gla proteins.

The other question is... is there a case for mk4? I have not looked at mk4 nearly at all when it comes to trialing.
I believe it would be one or the other though. Not both, and I'd really like to narrow this down. I think there might be more they don't know about long chain menaquinones atm. They also claim better bioavailability, much longer half life, (72 hours) and it too can convert to mk4

The ironic thing is the recommended drug dosage used in Japan to treat osteoporosis for MK4 is 45 to 90mg. Very similar to Accutane dosage.
Obviously I know it's not that simple, but here is a statement from a study looking at the relationship,
"MGP promoter has a perfect direct repeat which is nearly identical to the retinoic acid"
We know Accutane can have adverse effects on bone and growth. Vitamin K proteins seem to be on the opposite side of this.

Here's an example. I also think this might not be something you stop once you start it. This could be a catch up and prioritizing process.

Skull and Facial Widening from Vitamin K (MK4) - Peak Testosterone

For the guys who have ED or libido problems, you should really get a blood test. Your testosterone level, estradiol levels, and more can all play a role. Your ED should be relatively easy to fix with hormones.

14 minutes ago, svgputin1001 said:

For the guys who have ED or libido problems, you should really get a blood test. Your testosterone level, estradiol levels, and more can all play a role. Your ED should be relatively easy to fix with hormones.

Testro x would be a safer choice.

Expect side effects to slowly easetheir way into your life after isotretinoin exposure hair loss ,joint pain especially lower back pain will kick in dizziness mental dips welcome to the world of isotretinoin. That is reality.

Systemic dehydration is after all permanent. Expect chronic dry eyes , mouth , lips , and of course skin after exposure to this chemotherapy agent.

And the best you can hope for is symptom management.. Most important part dont mess with your skin trust me on this one our skin cell receptors are permanentymessed up and prolonged rubbing can litteraly induce a heart attack , no joke .