If you trace the source of that study, Virdis biopharma manufacturers,
MenaquinGold
It took 2 months at a dosage of 350mcg mk7 (theirs is one of the most potent on the market)
to normalize autonomic nervous system function. Some of this might be cardiovascular in nature.
350mcg is inline with dose finding studies to activate MGP. This isnt necessarily the maximum effective dose (which they havent found yet) but it might be close.
Dysautonomia for those that aren't aware can include: dry mouth, dry eyes, nerve pain, cognitive dysfunction, slow gastric emptying, erectile dysfunction and vascular constriction.
Hey guys
I want to update you about my status. I'm 100% fine.
I can live my life now and I realise how fucked up I was. Feels to good to be true after this mess. My mind is clear I can think normal what means there is no brain damage and I was so confused some days trust me...
I can build muscles fast and my bodyfat has reduced. I don't even eat healthy more like the opposite. One of the best things is the feeling when I listen to some music I get this nice feeling like before accutane but I dont want to talk to much. I hope you all are ok and I wish you the best.
Hello everybody.
I'm new here, I have important question. Does all of your side effects start while taking accutane? Or some of them came after?
My problems: ED, loss of libido, loss of motivation, low energy, depression. But all of them came up after 2 years after I stopped taking isotretinoin. I was taking medicine called Izotek, but its the same thing that you all were taking. My problems started when I started to take soy protein, then my testosterone went down. I have been waiting as I was told by doctors, but nothing changed in my feelings, but hormones are OK now, but symptoms are still there, and I dont know anymore if its SOY or ISO. And the problem is nobody can 100% be sure if I'm one of you or other group that have sexual dysfunction after eating soy...
Hi Everyone,
i just wanted to share with you guys my story. I just feel like I need to get this out and want to help others as well. It all started when I took Accutane in October of last year. I had a very bad bout of cystic acne which lasted for about 2 months, so my parents and I made the decision to try accutane.
This is where everything changed for me.
Within one month, my skin was beginning to clear, and I felt great. But one day while "doing the deed", I realized that I couldn't get an erection. I was having trouble getting to sleep as well and decided to get off the medication. From here the problems only multiplied. I had intense joint pain, continuing sexual difficulties, a raging candida infection, horrible insomnia and overall just depression. Its just a general feeling of unwellness that only you guys in the forum can relate to. I tried to ignore it but in August I hit a breaking point. The anxiety was just off the charts, and I just didn't feel like myself anymore. I felt like I was going insane and had no one to talk to about. I tried to hide it, and kept myself away from most social settings. As an 18 year old heading off to his first year of college, this hit me really hard. How would I live like this? How would I get into a relationship with no "working parts"? How would I compete in college track and filed (im an athlete)? just wanted my life back. Despite how I felt though, I knew I've never given up on anything I've ever done. So i set upon a mission to heal myself. I read countless forums, did plenty of research, and came upon the idea that there was an issue in my gut. I came to this conclusion because my digestion was horrible; pale stools and new bad food intolerances. I immediately began looking for ways to restore my gut backto health. Accutane is toxic, so I figured that if I improve my gut health, i will become less toxic and thus heal. I started many different diets, vitamins, digestive enzymes, herbs, and plenty of exercise. it was trial and error, until i finally found the right combination.
Well, I can say that its been 3 months, and I'm doing better. All of my side effects have improved greatly; erectile dysfunction practically gone, digestion improved, no joint pain, and I'm enjoying life again like a 19 year old. I'm optimistic that full recovery is just around the corner.
Im glad i could share my story, and would love to talk to other guys and teens like me who are going through the same thing.
2 hours ago, swistak007as said:Hello everybody.
I'm new here, I have important question. Does all of your side effects start while taking accutane? Or some of them came after?
My problems: ED, loss of libido, loss of motivation, low energy, depression. But all of them came up after 2 years after I stopped taking isotretinoin. I was taking medicine called Izotek, but its the same thing that you all were taking. My problems started when I started to take soy protein, then my testosterone went down. I have been waiting as I was told by doctors, but nothing changed in my feelings, but hormones are OK now, but symptoms are still there, and I dont know anymore if its SOY or ISO. And the problem is nobody can 100% be sure if I'm one of you or other group that have sexual dysfunction after eating soy...
Best to ask the person above your post as apparently theyre cured....
Im not sure how though, the message is vague...
Perhaps they just got lucky taking Vit C or something....
@swistak007as
Some of us have side effects that started while accutane, most of us have had side effects that came or worsened upon discontinuation, many of us have had both. And yes, there are some people who didn't get side effects until years later. Some get better with time, some get worse, some stay about the same. Apparently, most people who take the drug just experience things like temporary dryness. I've heard it said many times that this condition, post accutane syndrome, is due in part to genetics. Your right that you can't be 100% sure about the soy or iso being the cause, but given your symptoms and history of taking iso, you may want to stick around. You have any other symptoms? Hopefully they go away, even if thats just wishful thinking.
@Accutane: The Recovery
Thats good to hear that you are doing better. Can I ask what your current diet and regimen is?
Diet wise I have been eating no grains, no sugar, lots of leafy greens. I think its been beneficial. Hard to say really.
Anyone have any idea how taking finasteride has seemingly cured Idontknow1993? He was 7 years post, took fin, and now is back on his feet.
I also see its been a month since I posted on here about taking my own life, well i'm no longer so suicidal. I have been feeling bit a better, feel grounded, less like i'm living in a dream (or rather a nightmare). Life has become a bit less painful and a bit more enjoyable. Yay.
And this disease continues to be a mystery.
I am 20 years old and I took accutane at 17, I have been following this forum for about 2/3 years but I have never posted anything, I have sexual problems, depersonalization / anedonia, I am tired all the time, I tried several and several things along these 3 years... after seeing some recoveries and recovery from idontknow1993 I decided to try finasteride too, based on how the body's receptors works, being that everything you inhibit for a while your body creates more response to that and when you stop it comes back a lot stronger, so I'm giving this a chance, I do not worry so much about risking where I am.
I'm on the 13th of finasteride, I'm taking 5 mg to 4 days already, I still do not think I noticed any difference except a few strands of hair loosening from my hair in the bath when I walk by the hand, but it's very little, I get the impression being hotter, there are moments that I feel very hot and sweat a lot (although it is very hot weather, summer), acne has stopped for now, any difference I will warn you guys
for those who want more information and knowledge, have a very good forum with many intelligent people and several cases of pssd, pfs and accutane, the forum is called [removed]
I'm seeing success with CBD oil, one of the best medicines known to mankind, working wonders for my inflammation. and for neurology i've just met a connect (so random and lucky encounter the other night) with access to Psilocybin mushrooms (scroll to my previous posts for info on mushrooms). I'm also waiting for my semax and cerebrolysin in the mail as plan C and D. Going to use it in conjunction with my hyperbaric oxygen chamber.
I will try every alternative method available before I succumb to another pharma med. Be very careful reading some of these posts. They are relatively new accounts and I would take everything they say with a grain of salt.
19 hours ago, idontknow1993 said:Hey guys
I want to update you about my status. I'm 100% fine.
I can live my life now and I realise how fucked up I was. Feels to good to be true after this mess. My mind is clear I can think normal what means there is no brain damage and I was so confused some days trust me...
I can build muscles fast and my bodyfat has reduced. I don't even eat healthy more like the opposite. One of the best things is the feeling when I listen to some music I get this nice feeling like before accutane but I dont want to talk to much. I hope you all are ok and I wish you the best.
Very cool dude, thanks for the update. You make me reconsidering fin again just for a short period.
one thing i lost was my appreciation for music so glad u got it back
thanks, please keep us posted.
Will try it too in january
41 minutes ago, Walden Rev said:Very cool dude, thanks for the update. You make me reconsidering fin again just for a short period.
one thing i lost was my appreciation for music so glad u got it backthanks, please keep us posted.
Will try it too in january
Sorry im missing where he said it was Finasteride that was key??
Where does he say that?
12 minutes ago, TrueJustice said:Sorry im missing where he said it was Finasteride that was key??Where does he say that?
Look through his post history. He took fin for about 25 days and has been updating us on it.
46 minutes ago, Walden Rev said:Check his history
Cool - thx!!
So I like to compare approaches, if people are finding a cure through Finasteride does that put to rest any theories on recovering via Vit K supplementing??
Not that anyone ever said a full recovery can happen via K but why bother going down that path when apparently theres a full cure down another....
Just asking those who know a thing or two!!
On 4/16/2016 at 7:58 AM, Ruvik said:New bad news
Today I was visited for my severe sexual sides from accutaneby a urologist-andrologist in northern Italy, he says he sees penile fibrosis.I doubt this can explain accutane effectsany of you have similardiagnosis?
He prescribed me 2 exams, unfortunately, the months of waiting are so many, I will not have them made before summer
Penile Fibrosis from accutane. This can include the artery becoming hard and stiff or thickening.
He didnt have low testosterone.
Propecia can cause this same side effect.
Mercks controversial hair loss drugPropecia(generic:finasteride) has been linked topenile fibrosis, a serious sexual disorder which is also known as Peyronies disease.... Signs and symptoms ofPropecia-inducedpenile fibrosismay include excessive curvature of the penis ...
1 hour ago, TrueJustice said:Cool - thx!!So I like to compare approaches, if people are finding a cure through Finasteride does that put to rest any theories on recovering via Vit K supplementing??
Not that anyone ever said a full recovery can happen via K but why bother going down that path when apparently theres a full cure down another....Just asking those who know a thing or two!!
I like to see it as a hardware vs software approach.
hardware = receptor theory / fin / Ella pill / Ru486 / water fasts
Software = Vitamin K / Diet / Vit d etc
hardware is ofcourse riskier, imagine it like putting a new graphics card in your computer because the old one got overclocked and burned but the motherboard doesnt support the new one. Youre pretty fucked and the situation is even worse.
software is tweaking the old overclocked and burned graphics card to try and restore to its old standards. But with supplements you only go to a certain point and imo something like Vitamine K will not fix a chemodrug big guy MVP like Accutane.
Ofcourse, according to theory alot of software things should fix us, but it never did. Hell, a multi vitamin should restore is because the body should balance itself out right?
I look more into nootropics like semax and piracetam because they promote neurogenesis in the brain.
rick simpson oil was by far the best thing i tried and i believe i regained alot of life motivation because of it.
but one of my biggest asset was menory, its fucking gone right now because im fucking tiredbALL the time.
So give me the hardware approach, end of 2018 i will have my life back.
January ill do a small round of fin to deprivate my receptors and make th m active again.
Lets take this thing down. Its been too many years and ive tried every supplement there is.
Im going hardware.
good luck everybody, may one of us fix this shitter once and for all
P.s. As u can see im not that guy who knows a thing or two, i dont have the concetration and energy to back it up scientifically. But i done with the software approach, it didnt bring any good in the last 10 years so im moving on
This is what i'm mainly trying to accomplish first and foremost looking at vitamin k2 mk7.
I'm trying to "push" blood flow.
I'm trying to push blood flow so you never get light headed, brain fogged, dizzy, fatigued, or have lack of good sense of space in your environment. This is number one. Number two i'm trying to ease vascular constriction. This can be that "head pressure" pale skin, lack of saliva, dry eyes, kidney problems, gastric problems, ED. Im basically trying to strengthen the blood vessels to push good blood flow to regulate the vascular system.
Now you can look at heart rate variability and how it can affect erectile function.
Heart Rate Variability in Men with Erectile dysfunction
Purpose
The objective of this study is to investigate alteration of autonomic nervous system (ANS) activity in patients suffering from erectile dysfunction (ED) by comparing parameters of heart rate variability (HRV) between men with ED and healthy subjects.
Conclusions
Patients with ED exhibited different HRV parameters compared with normal controls. This suggests that the patients with ED may have some kind of imbalance in the ANS and it may be possible that general imbalance of the ANS is one of the causes of ED. Thus, HRV analysis may give valuable diagnostic information and serve as a rapid screening tool to evaluate altered ANS activity in patients with ED
Looking at k2 mk7 this could be a possibility to treat. It might depend on dosage and/or duration. Those further out from accutane could be more affected.
@Walden RevIf someone was to take thisseriously, or look at properly, I would like to know the exact dosage and duration of mk7 (even brand if you recall, because they are all different) you have taken. Also if you were taking anything else along with it at the time. Thanks.
Or anyone else that has taken mk7 if you have looked at this extensively, if you could tell me dosage and duration.
So im not wasting my time. Thanks again.
Now Foods mk7 k2.
solgar k2
but honestly, i like your theory and i really think you should pursue this road but im taking a different one.
copper should have fixed us in 2016 according to the theories
blue ice should have fixed us in 2015
active b complex with co factors in 2016
manganese in 2017
NAG in 2016.
i just dont believe i return to the doctor and say i fixed my dick, my memory, my lower back, my hair loss with 3 months of vitamin K
message to all the accutane sufferers around the world: 3 months of Vitamin K will fix 10 years of accutane horror.
This is why i go hardware.
P.s. I was taking Glandular alongside of it
[Edited link out]
On 12/13/2017 at 9:52 AM, guitarman01 said:This is what i'm mainly trying to accomplish first and foremost looking at vitamin k2 mk7.
I'm trying to "push" blood flow.
I'm trying to push blood flow so you never get light headed, brain fogged, dizzy, fatigued, or have lack of good sense of space in your environment. This is number one. Number two i'm trying to ease vascular constriction. This can be that "head pressure" pale skin, lack of saliva, dry eyes, kidney problems, gastric problems, ED. Im basically trying to strengthen the blood vessels to push good blood flow to regulate the vascular system.Now you can look at heart rate variability and how it can affect erectile function.
Heart Rate Variability in Men with Erectile dysfunction
Purpose
The objective of this study is to investigate alteration of autonomic nervous system (ANS) activity in patients suffering from erectile dysfunction (ED) by comparing parameters of heart rate variability (HRV) between men with ED and healthy subjects.
Conclusions
Patients with ED exhibited different HRV parameters compared with normal controls. This suggests that the patients with ED may have some kind of imbalance in the ANS and it may be possible that general imbalance of the ANS is one of the causes of ED. Thus, HRV analysis may give valuable diagnostic information and serve as a rapid screening tool to evaluate altered ANS activity in patients with ED
Looking at k2 mk7 this could be a possibility to treat. It might depend on dosage and/or duration. Those further out from accutane could be more affected.
@Walden RevIf someone was to take thisseriously, or look at properly, I would like to know the exact dosage and duration of mk7 (even brand if you recall, because they are all different) you have taken. Also if you were taking anything else along with it at the time. Thanks.
Or anyone else that has taken mk7 if you have looked at this extensively, if you could tell me dosage and duration.
So im not wasting my time. Thanks again.
If you do have time, you seem to have alot of energy to digg deep (thats what she said). Check out the thread which Tanedout started.
there are some great theories abiut progestins and receptor regulation
[Edited link out]
9 minutes ago, pimple pimp said:im about to start low dose accutane (under 20mg, most likely 10 mg/day)
how much were u guys on and for how long?
the 60mg+ camp seem to have it worst
I did 10mg/day and I feel like I'm one of the worst on here. You've probably heard this but don't do it. Don't play with your mental and physical health. You think life's hard now? Accutane never even solved my acne problem and now, well acne is one of my least concerns. You ever try a chromium picolinate + cinnamon supplement? Only thing besides accutane that has ever helped my acne in a significant manner.
4 minutes ago, Togg said:I did 10mg/day and I feel like I'm one of the worst on here. You've probably heard this but don't do it. Don't play with your mental and physical health. You think life's hard now? Accutane never even solved my acne problem and now, well acne is one of my least concerns. You ever try a chromium picolinate + cinnamon supplement? Only thing besides accutane that has ever helped my acne in a significant manner.
you were on 10 mg only/day for how long? thanks
2 hours ago, Walden Rev said:If you do have time, you seem to have alot of energy to digg deep
This is right on the surface. You dig too deep you might never come back up for air.
Im noticing some things on here I didnt notice before.
People have absolutely gone down the rabbit hole because they know something has happened or is happening to them but they dont know what.
Let me give you an example. This is just a random post from phoenix rising.
"This might be from aromatase inhibition, and not necessarily good. Be sure you are getting above optimal absorption of zinc, manganese and glycine, consider perhaps even adding glucosamine/chondroitin/collagen/gelatine whatever you tolerate and have enough nutrients to better absorb/metabolize. Manganese is needed more than usual for those who take high doses of B1."
^I see a little bit of insanity in this.
Looking on that forum you linked I see people trying to cure themselves from post ssri by taking low dose ssri. Its because they dont know what else to do.
Its all so messed up. If you're all about trialing fin, at least I guess we would have another opinion we could trust.
Just like someone else recently stated about accutane though, sometimes sides dont show up for quite some time later and then it might progress.
Also, none of this came from me.
copper should have fixed us in 2016 according to the theories
blue ice should have fixed us in 2015
active b complex with co factors in 2016
manganese in 2017
NAG in 2016.