7 hours ago, Justdry said:

thanks, ill try that after next monday.

Yeah, i have no sexual problems but i still feel its a hormonal issue causing no oil production.

Can you try and get Vit A tested as - not sure what the status is regarding Vit A after Accutane and we need to start getting spme data.
You shouldn't have too much trouble getting Vit D (nearly ev'1 low) cortisol, T and Estrogen FBC, thyroid, liver panel test, kidney test and CRP or and ESR (for inflamation). Prolactin important too.

Any gynecomastia or body fat distribution problems - all hormonal related.
Any problems making gains?

Been researching yes stressed
so I take it from what I read
wr have cell damage and cell death
of glands
so can we not fix this??

seems that maybe it damaged hypothalamus and that controls sleep and hormones and temperature nerves and more I guess

I think the drug ruined everything inside

im so annoyed a drug did all this

[Edited link out]

I believe thyroid and adrenal glands were damaged, hence hormonal problems.

An holistic approach to healing these should be the first approach to trying to fix this.

Many of the PFS guys talk about pregnenolone and the above article mentions it.
--------------------------------------------------------------------

We need to be more consistent with testing so we find patterns like PFS have done
[Edited link out]

On 20.2.2017 at 6:34 PM, Nemesisbrady said:

@roland1968 this sucks is there anything we can do???
ive looked into eye surgery problem is it causes dry eyes
no clue what to do 
I'm always exhausted 
I wake up every two-three hours
with my eyes stuck shut seollen
dry nasal passages and mouth cotton like
night sweats 
skin is just dead and pink and rashy 
have to exfoliate nose everyday it's so flaky and rub olive oil allllll over it and let it air dry 

Hi Brady,

I tried multiple things over the years but nothing really helped with the skin problems. So unfortunately I can not give you the ultimate cure as I have not found it myself. I would not recommend you eye surgery. I think it can make things much worse.

5 hours ago, Nemesisbrady said:

Been researching yes stressed
so I take it from what I read
wr have cell damage and cell death
of glands
so can we not fix this??

seems that maybe it damaged hypothalamus and that controls sleep and hormones and temperature nerves and more I guess 

I think the drug ruined everything inside 

im so annoyed a drug did all this 

Apoptosis of sebaceous glands would be irreversible.
 

18 hours ago, hatetane said:

Can you try and get Vit A tested as - not sure what the status is regarding Vit A after Accutane and we need to start getting spme data.
You shouldn't have too much trouble getting Vit D (nearly ev'1 low) cortisol, T and Estrogen FBC, thyroid, liver panel test, kidney test and CRP or and ESR (for inflamation). Prolactin important too.

Any gynecomastia or body fat distribution problems - all hormonal related.
Any problems making gains?

Surely 6 years post accutane my actual Vit A levels can't be so high - If i supplement with Vit A my skin does get drier but it doesn't cause the dry lips and eyes to come back, like when on accutane.

In regards to Liver, Kidney etc... I have no health issues except for dry skin, dry hair and slow wound healing so I wouldn't think there would be any problems in those areas.

Also - doesn't everyone say that their Vit A reading from their blood comes back fine and in normal ranges ?

2 hours ago, Roland1968 said:

Apoptosis of sebaceous glands would be irreversible.

But why wouldn't it kill all sebaceous glands - Parts of my face still create sebum but large patches of it don't. The rest of my body is absolutely fine. I don't believe death of sebaceous glands is the case.

2 hours ago, Justdry said:

4 hours ago, Roland1968 said:

Apoptosis of sebaceous glands would be irreversible.
 

But why wouldn't it kill all sebaceous glands - Parts of my face still create sebum but large patches of it don't. The rest of my body is absolutely fine. I don't believe death of sebaceous glands is the case. 

I think it can not be questioned, that isotretinoin induces apoptosis. But this does not mean, that it would kill all cells immediately. It is a question of the overall dose and a question of the receptor sensitivity.

Exact mechanism of action of isotretinoin is not known. It has been shown to induce apoptosis in various cells of the body including sebaceous glands, and thereby helping in the treatment of acne vulgaris.

Nelson AM, Cong Z, Gilliland KL, Thiboutot DM. TRAIL contributes to the apoptotic effect of 13-cis retinoic acid in human sebaceous gland cells. Br J Dermatol 2011;165:526-33.

8 minutes ago, Roland1968 said:

I think it can not be questioned, that isotretinoin induces apoptosis. But this does not mean, that it would kill all cells immediately. It is a question of the overall dose and a question of the receptor sensitivity.

Exact mechanism of action of isotretinoin is not known. It has been shown to induce apoptosis in various cells of the body including sebaceous glands, and thereby helping in the treatment of acne vulgaris.

Nelson AM, Cong Z, Gilliland KL, Thiboutot DM. TRAIL contributes to the apoptotic effect of 13-cis retinoic acid in human sebaceous gland cells. Br J Dermatol 2011;165:526-33.

So what about people who's skin hasn't produced oil for a number of years post accutane and then they regain oil production. Like the clippers guy a couple of pages ago. The sebaceous glands are either not dead, can repair themselves or be repaired.  

10 minutes ago, Justdry said:

21 minutes ago, Roland1968 said:

I think it can not be questioned, that isotretinoin induces apoptosis. But this does not mean, that it would kill all cells immediately. It is a question of the overall dose and a question of the receptor sensitivity.

Exact mechanism of action of isotretinoin is not known. It has been shown to induce apoptosis in various cells of the body including sebaceous glands, and thereby helping in the treatment of acne vulgaris.

Nelson AM, Cong Z, Gilliland KL, Thiboutot DM. TRAIL contributes to the apoptotic effect of 13-cis retinoic acid in human sebaceous gland cells. Br J Dermatol 2011;165:526-33.

So what about people who's skin hasn't produced oil for a number of years post accutane and then they regain oil production. Like the clippers guy a couple of pages ago. The sebaceous glands are either not dead, can repair themselves or be repaired.  

I don't know the clippers guy. Can you share a link?

48 minutes ago, Roland1968 said:

I don't know the clippers guy. Can you share a link?

He posted on page 466. Here's the main snippet that interested me:

''And I left this for last as I did reference a 'huge personal breakthrough.' For years I made a conscious decision to avoid all Vitamin A rich foods and I suspect that was a huge mistake. Over the past 6 months I've cleaned up my diet and start adding more plant based foods and juicing and the effect have been tremendous. Why should any of us avoid eating plant based foods? I was an idiot for ever doing so. If anything avoid eating over processed garbage and consume everything else in moderation.

How significant? Dry skin and brittle hair are a thing of the past. Even the joint issues! I sometimes wake up with my face as oily as it was during my teenage years.''

I don't think it's really a matter of oil production. There are plenty of people as they get older that don't have oily skin but still have healthy skin(ie can tan normally)
Also for example I used to dry the hell out of my skin with soap and acne creams before accutane and it never caused facial flushing like I get post accutane. I think the bad skin is more due to thinness and inflammation. The skin thinness can go with the body's general inability for some of us to put on body fat post tane. There also might be some mild dehydration going on as well

22 minutes ago, Justdry said:

He posted on page 466. Here's the main snippet that interested me:

''And I left this for last as I did reference a 'huge personal breakthrough.' For years I made a conscious decision to avoid all Vitamin A rich foods and I suspect that was a huge mistake. Over the past 6 months I've cleaned up my diet and start adding more plant based foods and juicing and the effect have been tremendous. Why should any of us avoid eating plant based foods? I was an idiot for ever doing so. If anything avoid eating over processed garbage and consume everything else in moderation.

How significant? Dry skin and brittle hair are a thing of the past. Even the joint issues! I sometimes wake up with my face as oily as it was during my teenage years.''

Thanks for sharing. Indeed that sounds very promising. How was he able to achieve those results? This part is very contradictory:

"For years I made a conscious decision to avoid all Vitamin A rich foods and I suspect that was a huge mistake. Over the past 6 months I've cleaned up my diet and start adding more plant based foods and juicing and the effect have been tremendous."

First he says avoiding VitA was a mistake. And the he says, ha startet to eat plant based food. But plant based food has no VitA. VitA is mainly in meat and fish. This sentence makes no sense.

25 minutes ago, guitarman01 said:

I don't think it's really a matter of oil production. There are plenty of people as they get older that don't have oily skin but still have healthy skin(ie can tan normally)
Also for example I used to dry the hell out of my skin with soap and acne creams before accutane and it never caused facial flushing like I get post accutane. I think the bad skin is more due to thinness and inflammation. The skin thinness can go with the body's general inability for some of us to put on body fat post tane. There also might be some mild dehydration going on as well

I agree - dryness is only one factor. fragile skin and sensitivity to sun light add to it.

This again sounds like a hormonal issue though -

I've always found it difficult to put on weight and i'm a much healthier weight post accutane than i was before i took accutane so i can't say skin thinness is due to body fat. I put on 30lbs working out and eating post accutane and my body fat % got quite high doing it.

I get what you're saying, but I'm not really talking about the skin being oily, it's just any activity from the sebaceous glands at all. The areas of my face that are perfect aren't ''oily'' but i know some sebum is being produced.

Causing your face to dry out through soap is different than something affecting your bodies ability to produce sebum at all.

Plant's contain beta carotene which the body converts to vit a as needed. This is a much more sensible option for us than pure vitamin A like that found in supplements, which seems to instantly cause toxic effects.

I've started eating carrots for the past 3 days. I'veavoided Vitamin A as much as i could for 6 years. Maybe this has also been my mistake.

http://www.onegreenplanet.org/natural-health/plant-based-nutrition-guide-vitamin-a-beta-carotene/

3 hours ago, guitarman01 said:

I don't think it's really a matter of oil production. There are plenty of people as they get older that don't have oily skin but still have healthy skin(ie can tan normally)
Also for example I used to dry the hell out of my skin with soap and acne creams before accutane and it never caused facial flushing like I get post accutane. I think the bad skin is more due to thinness and inflammation. The skin thinness can go with the body's general inability for some of us to put on body fat post tane. There also might be some mild dehydration going on as well

That's my feeling too. My sebaceous glands work but id doesn't help with redness (or maybe even worsens it?). My face skin seems thin. Also I cannot sweat from face.

Hi Brady and others mentioning they have the same facial/scalp skin issues. (Re-posting part of an earlier post that may be helpful)

You could try using a daily regimen of washing your face with a sulphur soap (make sure to pick one with good reviews/ingredients, I use 'keep it clean' a 10% sulphur soap) and afterwards moisturize with unrefined raw shea butter.

After accutane one of the problems I developed was progressively worsening rosacea and dermatitis on my face and scalp. For a long time I was able to keep it at bay using a carrier oil combined with oregano oil, I used this combination to kill the bacteria/fungi on my face that was part of the problem, but eventually the bacteria/fungi seemingly adapted and this was no longer effective. The sulphur/shea butter combination has been working for around 2years with no signs of diminished effectiveness. Also shea butter is great for skin in general and excellent at fighting dryness so def worth a shot. I only use this combination on my face as it doesn't seem effective for my scalp issues so use Nizoral instead, which is.

Also worth mentioning that the olive oil can feed whatever bacteria/fungus your skin/body is reacting too, I believe Warren mentioned something similar, if not exactly this, too.

Also, just a quick warning for anyone considering starting Iodine, don't want to deter anyone(I supplement with it myself) but it is dangerous to start doing so without making yourself very familiar with all the other things you have to take in combination to make it safe. The link below includes a lot of info, the levels of iodine recommended may be over the top though so worth reading around, there's good discussion on the site longecity that is worth reading too.
http://tinyurl.com/Iodine-Handout

WRT my last post saying that I didn't notice taking Iodine helping with flushing, I retract that as I can't be sure, it certainly didn't help with the dermatitis side of things but it is possible, maybe even likely that the rosacea (facial flushing) symptoms I had were independent from the dermatitis. I can't be sure as I was taking a lot of different steps to try fix things around the same time..

• Wiping out post accutane gut microbiome and replacing/rebuilding through use of large amount of diverse probiotic foods. Done in combination with a very restricted diet.. mainly chicken, eggs and large amts of veg with avoidance of certain suspected trigger foods.
• Using various supplements to heal the gut.
• On and off Vitamin D protocol, although this I am fairly sure had no impact on the skin issues.
• Iodine protocol.
• The topical skin strategies mentioned earlier as well as some experimentation with balancing the skin microbiota(was successful for some thrush issues and for angular chelitis, have had to re-treat these a few times but not for a long time now, these 2 issues left me with my last attempt to re-balance the gut. Still want to do some experimentation in the future to see if possible permanently solve facial/scalp dermatitis by trying to balance the life there).

Also for thin skin, things I haven't looked at extensively but hold some interest are topical Vitamin C for increasing collagen and maybe helpingwith epidermal differentiation(I'm not going to pretend to understand what this is at this moment in time but it's referenced WRT accutane and dermatitis here https://www.ncbi.nlm.nih.gov/pubmed/18572976 ) and topical Ubiquinol for elastin).

Anyway.. my intended brief post has degenerated into a long ramble so I'm going to stop! Hope something is helpful.

9 hours ago, Justdry said:

Surely 6 years post accutane my actual Vit A levels can't be so high - If i supplement with Vit A my skin does get drier but it doesn't cause the dry lips and eyes to come back, like when on accutane.

In regards to Liver, Kidney etc... I have no health issues except for dry skin, dry hair and slow wound healing so I wouldn't think there would be any problems in those areas.

Also - doesn't everyone say that their Vit A reading from their blood comes back fine and in normal ranges ?

What is established is low Vit D, everyone I think. I don't think many had Vit A tested because doctors don't see the point of it.
My understanding is that Vit A is sometimes deficient or more than likely it is the way that it is utilised by the body.
Maybe Vit A status has been established post accutane but I haven't been able to reach a conclusion.
Can you post anything that you have that will clarify the situation.

Thanks @warrah I'm becoming hopeless this is just idk
ill try that thank u
because everyday I have to scrape my nose and apply oil for it to feel normal for 15 hours
and then back to it
latley my skin has begun to get flaky and rashy
not sure maybe olive oul
but I also drink a lot of fruits veggies now vitamin a
then I hear leafy greens suppress thyroid

im at point where I'm just gunna drink eat shit smoke and shoot heroin
since ppl that do that look and feel healthier than me

@hatetane
ive had vitamin a levels tested

my levels were normal

but the retinol and other one
were normal but looked low normal

example 0.1-0.5
mkne were 0.1

All I know is tbis is not normal
to wake up every three hours and eyes being glued mucus strings crusty like u have conjunctivitis for 10 years
nasal passages feeling like a candle dried up in it
my ex was on remeron clonodine Xanax Effexor and like two others is diabetic eats shit food and drinks
and woke up no dryness at all
ige stopped all my psych meds to see if this dryness would be better
well all except Xanax been on 10 years as well
was on 5mg before bed now I'm down to .5
the psych meds are what caused my erectile issues
so for people with that look into the meds

im just sick of not knowing and what not to do
every symptom of sjorgens-Shrimers test was no tears
but biopsy and blood negative and extensive work done
thyroid like stuff-tsh was 5.20 in 2012
told it's dying off too much blood flow levothyroxine
150-119 in two months weight
go back oh it's not the meds ur thyroid is healed u can stop it if u want lol
now I'm told tsh is normal

these are all the symptoms I'm having

Feel like I've had almost every test in the world

only things that have flagged
are low iodine
low zinc
low vitamin d
low normal dhea
alt ast liver were high
triglycerides use to be high
cholesterol always high
pre diabetic from glucose drink
tsh ultra sound showed thyroiditis some how cured lmao
sxhrimers test showed no tears
cyst in sinus cavity back in 2008 no clue now
oh and sleep apnea yet I don't believe I have that as I'm under weight adenoids tonsils are small

thats all I can think of

b

25 minutes ago, Nemesisbrady said:

All I know is tbis is not normal
to wake up every three hours and eyes being glued mucus strings crusty like u have conjunctivitis for 10 years
nasal passages feeling like a candle dried up in it
my ex was on remeron clonodine Xanax Effexor and like two others is diabetic eats shit food and drinks
and woke up no dryness at all
ige stopped all my psych meds to see if this dryness would be better
well all except Xanax been on 10 years as well
was on 5mg before bed now I'm down to .5
the psych meds are what caused my erectile issues
so for people with that look into the meds

im just sick of not knowing and what not to do
every symptom of sjorgens-Shrimers test was no tears
but biopsy and blood negative and extensive work done
thyroid like stuff-tsh was 5.20 in 2012
told it's dying off too much blood flow levothyroxine
150-119 in two months weight
go back oh it's not the meds ur thyroid is healed u can stop it if u want lol
now I'm told tsh is normal

these are all the symptoms I'm having

1.Dandruff-dry scalp

2.Dry eyes -bad morning

Mucus discharge crusty blood shot contacts barely tolerable very annoying
have eye plugs restasis and xiidra Ive tried omega 3 flax seed

3.Dry nasalpassages

4.Skin rashes/flaking dermatitis acne laser marks from v beam
5.Flushing-hot sex exercise anxiety

6.Cold hands feet they get paler not raynaurds the whole hand and foot is paler not toes and fingers

7.Sleep issues-was told sleep apnea when I was 165 in 2009
i wake up every two hours
drveloped bags from sleep issues

8.Night sweats-This is new symptom not sure if it's serious since it's not meds

9.loose stools new was always constipated and then normal bowel movements

10.Weight loss-I've lost 15 in past two weeks with sweats and loose stools and fatigue

11.Fatigue-New one

12.Acid reflux-use to get it went away now I have it again my diet I did add sauce again and have been stressed over ex so maybe that is behind this

13.hives urticaria dermatapgropishim

14.Facial hair upper cheek near eyes never shaved there and I've got laser hair removal still there

15.Body shoulder acne never had body acne even before during after Accutane
not sure if it's the night sweats

16.black marks on face when hot sweat chromohydrosis Google said
this is a weird symptom since tane

17.hands cramp up when carrying stuff

may seem like nitpicking
but most of these are annoying not to mention the OCD bdd depression anxiety agoraphobia anger and insomnia on top of it

is there any lasers for dry rashy pinkness
seems diet does not help me at all
I've been on no dairy no eggs no night shade foods gluten wheat for three months
onoy drink water almond milk and fruits veggies

sorry for bitching all over this
just docsfailed me
meds
diet
supplements

Feel like I've had almost every test in the world

only things that have flagged
are low iodine
low zinc
low vitamin d
low normal dhea
alt ast liver were high
triglycerides use to be high
cholesterol always high
pre diabetic from glucose drink
tsh ultra sound showed thyroiditis some how cured lmao
sxhrimers test showed no tears
cyst in sinus cavity back in 2008 no clue now
oh and sleep apnea yet I don't believe I have that as I'm under weight adenoids tonsils are small

thats all I can think of

hey brady, i know it isnt a cure but zinc soap should get rid of flakes.

Lactoferrin test and supplement for dry eyes and dry nasal passage 
 

An Objective Look at Dry-Eye Syndrome

A new test for the amount of the protein lactoferrin on the ocular surface might hold the potential for diagnosis and treatment.

For decades, clinicians have had to rely on their subjective evaluation of signs and symptoms in order to accurately diagnose and treat dry eye and ocular surface disease. Recent years have witnessed a flurry of developments in the realm of objective dry-eye diagnosis, however, with several devices becoming available around the same time. The newest addition to these objective measurement tools is the Tear Microassay System from Advanced Tear Diagnostics. Here™s a look at how the system works.

 

Lactoferrin Explained

 

The Tear Microassay System measures the amount of the protein lactoferrin on a patient™s ocular surface, using it as a marker for dry eye.

 

œLactoferrin is a multifunctional protein that™s part of the transferrin family, explains Terrence O™Brien, MD, professor of ophthalmology at the University of Miami™s Bascom Palmer Eye Institute. Dr. O™Brien has experience working with lactoferrin as a marker for dry eye, and is interested in seeing what this new test may bring to the clinic. œIt™s more of a global marker, and it™s present not only in tears but also in saliva, mother™s milk and nasal secretions. It™s also one of the components of the immune response, has demonstrated significant antimicrobial activity and is part of the eye™s natural defenses. This antimicrobial aspect of it is one of the reasons why I™m interested in it. It™s been identified as one of the tear proteins that may be part of the innate defense of the mucosal surface, and it has bactericidal and even fungicidal properties. In addition to binding iron, which bacteria use as an element necessary for their growth, it also binds to the lipopolysaccharide of bacterial cell walls. The oxidized iron that™s part of lactoferrin oxidizes bacteria, forming peroxide. This action affects the membrane permeability and results in the breakdown of the bacteria.

 

œMy interest in this stems from this antimicrobial mechanism being part of the innate immune system, and I think the test may have broader applications, adds Dr. O™Brien. œFor example, it may be that lactoferrin levels can tell us which patients might be at risk for developing an infection from wearing contact lenses.

 

The Test

 

The lactoferrin test consists of introducing a micropipette into the patient™s canthus and harvesting a very small sample of tears, 0.5 µl. The sample is put in a diluent and the mixture is shaken, a step that amplifies the amount of lactoferrin. The mix is then placed in a small well on a strip, and, according to Advanced Tear Diagnostics™ Jeffrey Busby, the diluent chases the tear up the strip and, when the sample is placed in the microassay system, the system determines how much lactoferrin is in the sample.

A result of 1.4 is considered normal, and anything below that means the patient has dry eye. According to company studies, the test™s sensitivity is 83 percent, and it™s specificity is 98 percent. There is already a diagnostic code assigned to the test, as well. The system can also process different samples of tears to test for immunoglobulin E, to look for the presence of ocular allergy.

 

Now that clinicians can use lactoferrin levels to determine if a patient has dry eye, Dr. O™Brien says the next step is to study the results and see how they correlate with signs, symptoms and disease severity levels. œWe need to figure out the correlation between the quantitative nature of this test result and the severity of the disease, he says. Some progress has been made along these lines: In a small, non-published study that Dr. O™Brien conducted with Duke University™s Alan Carlson, MD, several years ago, they found lactoferrin levels may be associated with postop LASIK results. In the study, the researchers tested the lactoferrin of 32 patients before their LASIK procedures and then prior to their post-LASIK follow-up exams. Preoperatively, six patients had low lactoferrin, 21 had normal levels, and five had elevated lactoferrin. œWe found that those patients who had lower levels of lactoferrin preoperatively were more prone to regression of effect and a lesser outcome of laser vision correction, says Dr. O™Brien. Elevated lactoferrin suggested an increased risk for postop hyperopia. All of the low-lactoferrin patients had a postop refraction of -0.25 to -1.5 D; only 19 percent of the normal patients were outside the -0.25- to +0.25-D range; and 80 percent of the high-lactoferrin patients had hyperopic refractions of +0.5 D or greater. œIt™s possible that an LVC surgeon, or a surgeon planning on implanting an advanced technology IOL, who uses the lactoferrin test to screen patients could uncover individuals who have mild to moderate disease that could impact the outcome, says Dr. O™Brien. œSo, this might be a broad screening tool for OSD as well as a perioperative screening tool that could be used in advance of surgery to uncover patients who may be at risk for a lesser outcome. The surgeon could then treat them preoperatively in an effort to improve the ocular surface. 

 

As for the steps after a clinician finds that a patient has low lactoferrin, there is some evidence that lactoferrin supplementation can help. In a non-published study outlined in a letter to the editor in Ophthalmology, physicians from Tokyo administered oral lactoferrin to 10 patients with Sj¶gren™s syndrome and used 14 eyes of seven other Sj¶gren™s patients as controls.¹ The researchers reported that mean corneal sensitivity, tear breakup time, tear-film lipid layer thickness, vital staining, squamous metaplasia grades, symptoms and goblet cell densities all improved significantly after a month of lactoferrin supplementation. The parameters then worsened a month after supplementation ceased. The control group showed no significant changes. Dr. O™Brien cautions clinicians to evaluate oral supplements carefully, though. œIf lactoferrin is low, there are supplements available, he says. œBut these aren™t tightly regulated by the FDA, so evidence is lacking in terms of trials to tell us which form of lactoferrin would be ideal, which dosage is best and if it™s harmful to take too much. We have this problem with other supplements that people may take without knowing their true safety.

 

Making Sense of It All

 

Dr. O™Brien says clinicians now have to determine where lactoferrin testing fits into their dry-eye diagnostic paradigm.

 

œWe™re finding out that dry-eye disease involves a complex biological system of multiple molecules, with each playing a different role in terms of normal homeostasis of tear function, he says. œI think the lactoferrin will be complementary to other tests such as those for tear-film osmolarity and MMP-9 to help us screen for dry eye.

 

œLactoferrin might also have other implications in terms of how the protein really functions in the natural prevention of infection from organisms that blow onto the tear film, in contact lens wearers and in surgery patients, Dr. O™Brien continues. œHowever, more work needs to be done to bring a clinical meaning to the quantitative result of the test. To that end, studies are currently being coordinated and are getting under way, and I hope we™ll have some data soon in different clinical settings. 

@justdry thank u I've read good reviews scared to cleanse face since no oil
feel like washes age people more and dry is out I'll look into it thank u
maybe shea butter after for moisture
Im confused tho the bar of soap contains olive oil which I was told flares up Seb Derm

Can we share some positive experiences from accutane here? I took it for 3 months at a pretty low dose and it did wonders for me. Had terrible cystic acne just awful and nowadays I just get a pimple here and there. The side effects were only temporary while I used the drug now I'm just like I was before.

It is a powerful drug who will change peoples life. It's just important that you use the right doses otherwise it can leave you with permanent side effects. I reckon the people who have permanent problems afterwards took a too high dose or are extra sensitive in a way. This thread makes it seem like it's a shit drug when it really saves peoples life.

@extazThis thread is a place for people who experienced an adverse drug reaction to talk about potential solutions. It's not necessarily the best place to talk about success stories, because we already had a negative outcome. I obviously acknowledge some people had positive experiences but our negative experiences deserve attention too. This drug has been linked to many different complications. I detail some studies in this post.

Personally, the highest dose I took was 40 mg per day. Some people who experienced an adverse drug reaction took even lower doses for a shorter amount of time than me. That's just the risk you take when you ingest this drug. The FDA has actually acknowledged that severe adverse drug reactions probably occur 10 times more often than they are reported. So although they may not be common, we're not getting the full picture when we look at statistics or correlation studies. That's why I often post *mechanism of action* studies when I talk about the potential dangers of Accutane.

2 hours ago, extaz said:

I reckon the people who have permanent problems afterwards took a too high dose or are extra sensitive in a way.This thread makes it seem like it's a shit drug when it really saves peoples life.

Interesting theory. Well, it's also destroyed lives, hence this particular thread with said title.

Millions have been prescribed the drug. The majority of them successful. You won't see the positive cases frequent the internet since they have moved past that particular chapter in their life. Unfortunately, not everyone is in the same boat.

I realized that my previous reply was not really respectful, sorry. Of course this is a thread about people who suffering from longterm damage from accutane and that's really sad that they have to go through this. I guess it's a tough price to pay to get rid of your acne forever. You can discuss wether it would be worth to get rid of cystic acne and be left with some longterm side effects or have cystic acne for the rest of your life and don't live with side effects though. Personally I would prefer the former option. 

Cheers!