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C'mon, really no need to call someone a fool. Fuck, it's hard enough with all the shit we have to deal with after tane, go easy on people pls.
I'm open to everyone's opinion - after smashing down all kinds of supplements over the last 15 years or so I'd have to agree with the forest fire/ spray bottle analogy, for the most part they aren't a cure!
I'm much more open to trying drugs, I don't really want to but what choice do we have?? Should I just accept that this is how it's gonna be for the rest of my life with these tane side effects - fuck that!!
I will do my homework on drugs though, we know all too well that they come with their own side effects.....don't we....
2 hours ago, ehohel said:I know that 23andme already made tons of research/links to finding cures to some diseases.
23andMe questionnaires ask about diseases you suffer from as well as prior Isotretinoin exposure. Everyone should fill them out, even though 23andMe's scope is limited. The real (genetic) meat is discovered when you run your genes through a third-party analysis. I will share some of my findings in the hopes of finding some correlations among us, since 23andMe is working off of a small subset of genes (assuming they ONLY study the genes they inform you about).
I will now list the mutations that stuck out to me (credit: Promethease). If others can brainstorm POTENTIALLY relevant genes, chime in.
- APOE-4 carrier (2x increased Alzheimer's risk, associated with increased susceptibility to cognitive decline)
-rs738409 (C;C) (5x higher risk of fatty liver)
- rs2187668 (A;A) (Greater risk of developing autoimmune disorders including Lupus and Celiac disease; appears to be a VERY rare gene)
- rs351855 (T;T) (Gene found in 3% of population that accelerates cancer progression)
- gs155 (CYP3A5 non-expressor; reduced ability to synthesize many medications and "steroid hormones testosterone, progesterone and androstenedione")
- Lots of autism genes and some genes suggesting lower empathy. (This stuck out to me due to my emotional numbing and cognitive issues post-Accutane. However, APOE-4 probably plays a role as well.)
- MTHFR mutation (overblown, if you ask me, but everyone talks about this)
Can other people check for these mutations? Search by the numbers, not letters. The gs155 gene (CYP3A5 nonexpressor) may play into the 5-Alpha Reductase Inhibitor theory! I do have clinically undetectable levels of cholesterol, which is mediated by that gene as well. Accutane may have interacted with some of our predispositions.
27 minutes ago, ACCUiTy_drANE said:23andMe questionnaires ask about diseases you suffer from as well as prior Isotretinoin exposure. Everyone should fill them out, even though 23andMe's scope is limited. The real (genetic) meat is discovered when you run your genes through a third-party analysis. I will share some of my findings in the hopes of finding some correlations among us, since 23andMe is working off of a small subset of genes (assuming they ONLY study the genes they inform you about).I will now list the mutations that stuck out to me (credit: Promethease). If others can brainstorm POTENTIALLY relevant genes, chime in.
- APOE-4 carrier (2x increased Alzheimer's risk, associated with increased susceptibility to cognitive decline)
-rs738409 (C;C) (5x higher risk of fatty liver)
- rs2187668 (A;A) (Greater risk of developing autoimmune disorders including Lupus and Celiac disease; appears to be a VERY rare gene)
- rs351855 (T;T) (Gene found in 3% of population that accelerates cancer progression)
- gs155 (CYP3A5 non-expressor; reduced ability to synthesize many medications and "steroid hormones testosterone, progesterone and androstenedione")
- Lots of autism genes and some genes suggesting lower empathy. (This stuck out to me due to my emotional numbing and cognitive issues post-Accutane. However, APOE-4 probably plays a role as well.)
- MTHFR mutation (overblown, if you ask me, but everyone talks about this)Can other people check for these mutations? Search by the numbers, not letters. The gs155 gene (CYP3A5 nonexpressor) may play into the 5-Alpha Reductase Inhibitor theory! I do have clinically undetectable levels of cholesterol, which is mediated by that gene as well. Accutane may have interacted with some of our predispositions.
I have theAPOE-4 carrier, and gs155 non expressor off the top of my head. I did have something about higher autoimmune disease chance, not sure if it's that same gene, I'll post some more tomorrow when I check again.
No MTHFR mutations which is good.
I have GS155 as well. I don't think I have the same variants on your other genes, as far as I can tell.
So based on what you guys are saying with these hormone and gene results, the question I need to ask is what is an endocrinologist likely to put us on???
If I go back to one and they say just take "selenium" I'm gonna punch them in the face.
Also, any advice on what to specifically ask for with a blood test would be welcome. Of course they'll look at testosterone etc but if there's anything deeper and tane specific pls let me know!!?
3 hours ago, ACCUiTy_drANE said:23andMe questionnaires ask about diseases you suffer from as well as prior Isotretinoin exposure. Everyone should fill them out, even though 23andMe's scope is limited. The real (genetic) meat is discovered when you run your genes through a third-party analysis. I will share some of my findings in the hopes of finding some correlations among us, since 23andMe is working off of a small subset of genes (assuming they ONLY study the genes they inform you about).I will now list the mutations that stuck out to me (credit: Promethease). If others can brainstorm POTENTIALLY relevant genes, chime in.
- APOE-4 carrier (2x increased Alzheimer's risk, associated with increased susceptibility to cognitive decline)
-rs738409 (C;C) (5x higher risk of fatty liver)
- rs2187668 (A;A) (Greater risk of developing autoimmune disorders including Lupus and Celiac disease; appears to be a VERY rare gene)
- rs351855 (T;T) (Gene found in 3% of population that accelerates cancer progression)
- gs155 (CYP3A5 non-expressor; reduced ability to synthesize many medications and "steroid hormones testosterone, progesterone and androstenedione")
- Lots of autism genes and some genes suggesting lower empathy. (This stuck out to me due to my emotional numbing and cognitive issues post-Accutane. However, APOE-4 probably plays a role as well.)
- MTHFR mutation (overblown, if you ask me, but everyone talks about this)Can other people check for these mutations? Search by the numbers, not letters. The gs155 gene (CYP3A5 nonexpressor) may play into the 5-Alpha Reductase Inhibitor theory! I do have clinically undetectable levels of cholesterol, which is mediated by that gene as well. Accutane may have interacted with some of our predispositions.
Here are mine:
APOE: C;T (half bad)
RS738409; G;G (all good)
rs2187668 ; G;G (all good)
gs155; non-expressor
I have many autism genes. No MTHFR issue.
Btw, I'm through my 4 weeks Ostarine cycle. Possibly the best gains I've had in my 4 years of training. No sides. All good. I'll play more with SARMs after taking a little break with the PCT I' m going through right now (Longjack + DIM and other supplements). Nothing is perfect yet but I would say easily, with all the things I've tried since subbing here in July, I'm definitely at my very best mentally and physically.
I maintain, and I will AGAIN reiterate as nobody here seems willing to discuss it. TRY IODINE. MEGADOSE IT. LOOK IT UP.
42 minutes ago, Kynarr said:Here are mine:
APOE: C;T (half bad)
RS738409; G;G (all good)
rs2187668 ; G;G (all good)
gs155; non-expressorI have many autism genes. No MTHFR issue.
Btw, I'm through my 4 weeks Ostarine cycle. Possibly the best gains I've had in my 4 years of training. No sides. All good. I'll play more with SARMs after taking a little break with the PCT I' m going through right now (Longjack + DIM and other supplements). Nothing is perfect yet but I would say easily, with all the things I've tried since subbing here in July, I'm definitely at my very best mentally and physically.
I maintain, and I will AGAIN reiterate as nobody here seems willing to discuss it. TRY IODINE. MEGADOSE IT. LOOK IT UP.
Its possible though to overdo Iodine - side effects can wreak havoc on the thyroid from what I read.
I want to take it as I have it in liquid form but I worry that I'll fuck something else up by taking it?
I've read about overusing it, plus thyroid tests out ok in recent blood work Don't know what to do??
First of all sorry for my not soo good english language and then Hi to all guys who have trouble with these state of mind and some unexplain issues. And thanks a guy who has a will to start a topic over the internet!
I'm 20 when i was taking a drug Roacutane in small doses but for the very vest time when i take just a one pill i feel strange! Yes i'm i guy who analizying and observed every second what is happenig to him, because i love psihology, human body and how brain works.. I'm 27 years old and stil no solution and i stil have problems with my life. Depression and Axiety is dominating. I must say that i never ever had problems before in my life..
But in just in 2 months i was very depressed and was force in 3 months to stop taking drug. Now I go to Psihotherapy twice in one week.
And i just know that depression was concevencies not the cause( my only problem is i lost mother in 9year) and period!
Soo to make story short and be a guy of help .
All we have to detox body definetilny, eat a supstance to improve serotnin level, like banana, cimet, fish and etc..
PS: My first qestion did anyone tried "kurkuma" aparently she is the best plant on the world?
On 12/4/2016 at 0:24 PM, Ruvik said:Anyone experiment difficulty finding words during a conversation or or feeling diminished cognitive abilities?
Some day I feel like my brain is not totally ative
YES YES YES, ! After stop taking accutane (3months) level of cortisol (hormon of stress) was increase.. So i stress everyday without knowing why..
On 12/9/2016 at 2:44 PM, TrueJustice said:Its possible though to overdo Iodine - side effects can wreak havoc on the thyroid from what I read.
I want to take it as I have it in liquid form but I worry that I'll fuck something else up by taking it?
I've read about overusing it, plus thyroid tests out ok in recent blood work Don't know what to do??
As far as I can tell, just about everyone in the western society, including most experts, have been lead to believe that Iodine is potentially very dangerous. It's not. Just account for the average japanese taking 13.8mg a day on average. Now add the fact that we intake so much chloride, fluoride, bromide, and you can easily see how Iodine would be very, very hard to overdose from. I'm slowly ramping up my dosage to 50mg a day while taking the many co-factors, and I feel fucking awesome. I don't know how else to say it and how many times to repeat myself. I cured my hypersomnia. I have insane amounts of energy, I feel abnormally aggressive, in a good way. Strength at the gym improves continuously. Joints are better. Less overall dryness.
I'm not saying this is the cure, because I don't think it is. But if you consider that halogens calcify the very same glands that accutane ruins, then we're fixing a very common problem through Iodine. I've been trialing tons of things just in the past few months and I won't stop until I'm more than cured, but my god you guys have got to stop discussing how accutane is bad, or how you have X or Y side effect. Everyone knows by now. What we need are solutions, trials, data, thoughts, info.
Try, share. Try again, share more. Let's fix this.
http://jeffreydachmd.com/wp-content/uploads/2014/03/The-Guide-to-Supplementing-with-Iodine-Stephanie-Burst-ND.pdf
https://docs.google.com/document/d/1IzFKo-r2-Nn8_z0KUrOhHdlanzSuhkuV3QO03XF6YTY/edit
https://docs.google.com/document/d/139Xa8u8kgNVT-K17TxYvsM7qsSfusxyvloIXWbU92rg/edit
[Edited link out]
On 12/9/2016 at 8:43 AM, ehohel said:I have the APOE-µ4 carrier, and gs155 non expressor off the top of my head. I did have something about higher autoimmune disease chance, not sure if it's that same gene, I'll post some more tomorrow when I check again.
No MTHFR mutations which is good.
I have GS155 and .APOE-µ4 (C;C) (double bad)
ALSO GUYS, PLEASE LOOK AT rs727153 AND SEE IF YOU HAVE ANY G ALLELES!!
On 12/9/2016 at 11:57 AM, Kynarr said:Here are mine:
APOE: C;T (half bad)
RS738409; G;G (all good)
rs2187668 ; G;G (all good)
gs155; non-expressorI have many autism genes. No MTHFR issue.
Btw, I'm through my 4 weeks Ostarine cycle. Possibly the best gains I've had in my 4 years of training. No sides. All good. I'll play more with SARMs after taking a little break with the PCT I' m going through right now (Longjack + DIM and other supplements). Nothing is perfect yet but I would say easily, with all the things I've tried since subbing here in July, I'm definitely at my very best mentally and physically.
I maintain, and I will AGAIN reiterate as nobody here seems willing to discuss it. TRY IODINE. MEGADOSE IT. LOOK IT UP.
One of my tests revealed high ANTI THYROID PEROXAB, like in hashimotos.. we should be trying to ingest LESS IODINE, not more
On 12/9/2016 at 6:36 PM, exitrade said:Check this out, It might be of help.
duuuude... check this out: cadmium fucks up exactly what we're trying to fix. how can we lower cadmium? propecia guys had success with this, and a lot of studies back it up.. http://www.propeciahelp.com/forum/viewtopic.php?t=3825 ...
http://www.ncbi.nlm.nih.gov/pubmed/18972399 i also have very high ldh.. im gonna work on lowering cadmium with zinc and garlic..
18 minutes ago, helpmeoutbuddies11 said:anyone still have incredibly thin and sensitive skin after accutane? how did you treat it?
this is my biggest problem. i dont care about my not working penis or the depression. My skin is increasingly thinning to the point where I look like i have progeria. I'm hardly exaggerating. Nothing fixes it. No hyaluronic. No increasing androgens, etc.
13 hours ago, macleod said:Isotretinoin is capable of genetic transcription, not too many chemicals are, but it is definitely one. I have posted a link hundreds of pages back that shows this. It can alter dna.
Can you post it again? I don't want to go digging "several hundred pages back"
8 hours ago, marlin15 said:this is my biggest problem. i dont care about my not working penis or the depression. My skin is increasingly thinning to the point where I look like i have progeria. I'm hardly exaggerating. Nothing fixes it. No hyaluronic. No increasing androgens, etc.
You took accutane for 2 months right?
8 hours ago, marlin15 said:this is my biggest problem. i dont care about my not working penis or the depression. My skin is increasingly thinning to the point where I look like i have progeria. I'm hardly exaggerating. Nothing fixes it. No hyaluronic. No increasing androgens, etc.
Yep. My face, besides always being red and having severe blushing and flushing problems, is extremely thin and incredibly shiny. I heard emu oil can thicken skin, but hardly think that'll do the trick...
Weltschmerz47
I'll let you read this then. Once you're done reading this, buy Iodine and report how you feel. You've taken Accutane. A little essential element shouldn't scare you.. 
Oh btw, Iodine flushes Cadmium..... ^^
10 hours ago, Weltschmerz47 said:anyone have head and neck cancer run in family?
or anything likeMeniere's disease?
Well since we took CHEMO getting cancer may actually be reduced I call it a silver lining in a dark cloud.
Thanks, Kynarr for understanding just how valuable iodine is!!! you just have to research and experiment. Iodine has allowed me to survive thus far. MY thyroid tests show up "normal", but my god my thyroid is NOT normal. You will notice overractive thyroid symptoms RIGHT away after taking too much. . Just back off, and you'll be fine. I'm sick of others throwing iodine under the bus from sheer lack of understanding. I was scared too when I first started, but you get good at dosing over time and learning to listen to your body.
Also, you guys should look into fulvic acid. Too many benefits to go into here, but research it. It wasn't until I started taking this that that gnawing sensation of hunger would go away, it's because it virtually eliminates cravings by giving your body virtually all of the nutrients it needs. But again, taking ONE thing is not a cure-all [Edited link out]I like how it's kicked candida's ass too. My body isn't craving sugar at all.
3 hours ago, MovingOnMusicGal said:Thanks, Kynarr for understanding just how valuable iodine is!!! you just have to research and experiment. Iodine has allowed me to survive thus far. MY thyroid tests show up "normal", but my god my thyroid is NOT normal. You will notice overractive thyroid symptoms RIGHT away after taking too much. . Just back off, and you'll be fine. I'm sick of others throwing iodine under the bus from sheer lack of understanding. I was scared too when I first started, but you get good at dosing over time and learning to listen to your body.
Also, you guys should look into fulvic acid. Too many benefits to go into here, but research it. It wasn't until I started taking this that that gnawing sensation of hunger would go away, it's because it virtually eliminates cravings by giving your body virtually all of the nutrients it needs. But again, taking ONE thing is not a cure-all https://www.msminerals.com/Portals/0/Downloads/about_humic_Fulvic_substancesII.pdf I like how it's kicked candida's ass too. My body isn't craving sugar at all.
Yeah but aren't you on CBD oil too??
Why do you need Iodine as well?
Just trying to connect the dots, if I can eliminate another unnecessary supplement I will. If iodine is the key great, just doing my homework before getting on it.
47 minutes ago, TrueJustice said:Yeah but aren't you on CBD oil too??Why do you need Iodine as well?
Just trying to connect the dots, if I can eliminate another unnecessary supplement I will. If iodine is the key great, just doing my homework before getting on it.
Personally I haven't found any difference in supplementing iodine. But if it helps you, go for it.