Day 3 of taking one pill (450mg) of saw palmetto per day. Penis is responding much better to visual stimului than before. Still not like it used to, bit much better. Bloodflow during erections seems better as well. The glans especially is filling up with more blood than previously.

On a side note, I read that cannabis is a DHT-Inhibitor also. Could be why some people see improvements using that Avenue (along with the increased dopamine of course). Also heard that antibiotics increase AR expression. I remember seeing some people cured themselves using two specific antibiotics, so maybe that's why they saw some healing.

Best DHT Booster? I say Creatine, other ideas?

Why anti DHT should treat accutane sides? sound like countersense,

My side effects sound like DHT Low

2 hours ago, QuietSoldier said:

On a side note, I read that cannabis is a DHT-Inhibitor also.

That's very interesting, also it seems its the THC and CBN cannabinoids which are key, not CBD. Study below.

http://www.ncbi.nlm.nih.gov/pubmed/6249575

Marihuana and its constitutents delta 9-tetrahydrocannabinol (delta 9-THC) and cannabinol (CBN) were tested for their ability to interact with the androgen receptor in rat prostate cytosol. Smoked marihuana condensate, delta 9-THC, and CBN inhibit specific binding of dihydrotestosterone (DHT) to the androgen receptor with a dissociatin constant of the inhibitors (Li) of 2.1-5.8 X 10(-7)M. in addition, other metabolites of delta 9-THC were also androgen antagonists. This data suggests that the anti-androgenic effects associated with marihuana use results, at least in part, from inhibition of androgen action at the receptor level.

1 hour ago, Ruvik said:

Best DHT Booster? I say Creatine, other ideas?

Why anti DHT should treat accutane sides? sound like countersense,

My side effects sound like DHT Low

The symptoms are like very low DHT, but you probably don't have low DHT - my DHT levels were tested as follows;

- DHT = 4.1 nmol/L (ref range 0.9 - 2.90)

So DHT is actually very high, over 30% above the top end of the reference range, yet I have symptoms of very low DHT.

3 hours ago, tanedout said:

That's very interesting, also it seems its the THC and CBN cannabinoids which are key, not CBD. Study below.

http://www.ncbi.nlm.nih.gov/pubmed/6249575

Marihuana and its constitutents delta 9-tetrahydrocannabinol (delta 9-THC) and cannabinol (CBN) were tested for their ability to interact with the androgen receptor in rat prostate cytosol. Smoked marihuana condensate, delta 9-THC, and CBN inhibit specific binding of dihydrotestosterone (DHT) to the androgen receptor with a dissociatin constant of the inhibitors (Li) of 2.1-5.8 X 10(-7)M. in addition, other metabolites of delta 9-THC were also androgen antagonists. This data suggests that the anti-androgenic effects associated with marihuana use results, at least in part, from inhibition of androgen action at the receptor level.
The symptoms are like very low DHT, but you probably don't have low DHT - my DHT levels were tested as follows;

- DHT = 4.1 nmol/L (ref range 0.9 - 2.90)

So DHT is actually very high, over 30% above the top end of the reference range, yet I have symptoms of very low DHT.

Hormonal Regulation of 5AR

Dehydroepiandrosterone (DHEA) up-regulates 5AR activity.¹ Progesterone inhibits 5AR activity.²These two hormones can be easily and accurately assessed on a 24-hr urine hormone profile.

Increased5a-Reductase Activity

Elevated5AR activityis associated with obesity and insulin resistance in both men and women.³In women, increased 5AR activity is associated with polycystic ovary syndrome (PCOS) and hirsutism.⁴In men, elevated 5AR activity isassociatedwithbenign prostatic hypertrophy (BPH) and premature baldness.⁴

5- Reductase Inhibitors

Some inhibition of 5AR may be desirable when 5AR activity is seen to be quite elevated. Natural 5AR inhibitors can provide effective moderate inhibition without shutting down 5AR altogether, which is seen with 5AR inhibiting drugs. Natural 5AR inhibitors include:

• Gamma-linolenic (GLA) , docosahexaenoic acid (DHA), and other fatty acids.^5,6
• Serenoa repens (Saw palmetto)^7,8,9,10
• Zinc^11,12

Research on the effects of zinc on 5AR has shown that its inhibitory effects can be potentiated by vitamin B6. Supplements containing highly concentrated Saw Palmetto extracts may result in over-inhibition of 5AR. 5AR activity can be monitored in a 24-hour urine hormone profile.

Over-inhibition of 5AR decreases the production of dihydrotestosterone (DHT) resulting in increased levels of testosterone. The consequent aromatization of testosterone a estradiol may cause gynecomastia, a known side effect of 5AR inhibitor drugs.

Finasteride and Dutasteride

Patent medicines that inhibit 5AR are used to treat benign prostatic hyperplasia, prostate cancer, and baldness (androgenic alopecia). Two of these patent medicines are finasteride (Proscar, Propecia) and dutasteride (Avodart). Currently, millions of men around the world take these drugs (as well as supplements mentioned above) to inhibit 5AR enzyme and decrease the production of 5a-DHT. There is evidence to suggest that one of the most potent inhibitors, finasteride, may cause residual impotence after discontinuation and possibly breast cancer in men.^13,14Finasteride has been on the market since the early 1990s.

Risks of adverse drug reactions (ADRs) to 5AR inhibitors increase with dose. Common ADRs with these drugs include impotence, decreased libido, and decreased ejaculate volume. Rare ADRs include breast tenderness and enlargement, and allergic reaction.

http://www.ncbi.nlm.nih.gov/pubmed/3207614

http://www.ncbi.nlm.nih.gov/pubmed/11075290

so.......

hemp seeds have the highest available GLA ofany food.

zinc+b6 totally shut down 5AR.

b6(p5p) involved in all of the Taurine pathways.

I don't know why you focus on DHT, if i remember it's not3a-diol G that you should look into?

By the way i just looked into it and zinc raise DHT, not reduce it (maybe it inhibit only one type or 5AR?):
http://www.ncbi.nlm.nih.gov/pubmed/8613886
http://www.ncbi.nlm.nih.gov/pubmed/7271365

Libido issue is adrenal related, and prostate + testis also ofc, try some glandular's you'll see. Anyway you can't test for enzymes or receptors, and can't do anything about it except let the body fix it itself, and apparently there is no issue with 5ARsince someone posted their DHT results and it was high. Still searching the wrong way for solutions.. You don't have issues with receptors 10 years after accutane, and you don't need to take accutane to have libido issues. Specific treatment about accutane is just about restoring homeostasis between vitamin A & D, can't do anything more, the rest is standard physiology and so detox & damage repair.

15 minutes ago, anonyy said:

I don't know why you focus on DHT, if i remember it's not3a-diol G that you should look into?

By the way i just looked into it and zinc raise DHT, not reduce it (maybe it inhibit only one type or 5AR?):
http://www.ncbi.nlm.nih.gov/pubmed/8613886
http://www.ncbi.nlm.nih.gov/pubmed/7271365

Libido issue is adrenal related, and prostate + testis also ofc, try some glandular's you'll see. Anyway you can't test for enzymes or receptors, and can't do anything about it except let the body fix it itself, and apparently there is no issue with 5ARsince someone posted their DHT results and it was high. Still searching the wrong way for solutions..

For me, zinc didn't do what I needed it to. All it really did was give me a bigger load upon ejaculation, and maybe slightly harder erections. My problem stems from not being able to get an erection when I need to, and zinc didn't help in this area. DHT-Inhibtors (saw palmetto) have been though as crazy as it seems.

Also, it's not an adrenal issue (at least for me). I've taken glandulars before and they did nothing for my libido.

BTW You're not understanding what I've been saying. You're right that it's not about the DHT. It's about how our androgen receptors have been desensitized to the DHT. When I say I'm finding success from using a DHT-Inhibitor, it's not because i'm lowering my DHT. It's because the 5ar-inhibitor is increasing the sensitivity of my ARs.

This was posted a number of pages back explaining the whole theory. http://www.protocol-online.org/forums/uploads/monthly_08_2010/msg-19273-027408800 1282061244.ipb

You can disagree with me if you want, but I've tried every other path discussed on this forum with no success. Not many people get cured sexually because no one would dare touch another 5ar-Inhibitor after their experience with Accutane. But I suggest people try it.

Wow, was thinking about going on Accutane for my persistent comedonal acne because I want my life back. Opinion may have changed

48 minutes ago, QuietSoldier said:

For me, zinc didn't do what I needed it to. All it really did was give me a bigger load upon ejaculation, and maybe slightly harder erections. My problem stems from not being able to get an erection when I need to, and zinc didn't help in this area. DHT-Inhibtors (saw palmetto) have been though as crazy as it seems.

Also, it's not an adrenal issue (at least for me). I've taken glandulars before and they did nothing for my libido.

BTW You're not understanding what I've been saying. You're right that it's not about the DHT. It's about how our androgen receptors have been desensitized to the DHT. When I say I'm finding success from using a DHT-Inhibitor, it's not because i'm lowering my DHT. It's because the 5ar-inhibitor is increasing the sensitivity of my ARs.

This was posted a number of pages back explaining the whole theory. http://www.protocol-online.org/forums/uploads/monthly_08_2010/msg-19273-027408800 1282061244.ipb

You can disagree with me if you want, but I've tried every other path discussed on this forum with no success. Not many people get cured sexually because no one would dare touch another 5ar-Inhibitor after their experience with Accutane. But I suggest people try it.

have you ever had your prolactin levels checked?

google prolactin and libido ED and P5P

http://www.propeciahelp.com/forum/viewtopic.php?f=5&t=10060&p=98688

lot of fin stuff comes up.

3 years detox & other factors helped me with libido issues, never took anything about that theory of receptors sensitivity, and i don't think that theory can still be valid 10-20 years after. Receptors issues like we see with drug addict, are corrected within max 2 years, no more. and even that is just a symptom. you can't alter it in the other way artificially without causing more issues, and it will last only as long as you take the altering drug.
if you are far too toxic i believe glandular's can fail to work, but i think it's "rare". it's also related to pituitary, i personaly took both.

Unless you have severe cystic nodular acne don't even think about it , clean up you diet find your trigger foods , don't $%& up your life overpimples .

I quit finasteride and recovered. Then i smoked weed and crashed hard with PFS. Its def a 5Ari.

How many here have tested DHT levels. When I went to an endocrinologist a few years ago she said she could test it, but usually its inaccurate, so never did.

I've had DHT tested and result was 1.09 nmol/l (1.03 - 2.92). I got unnatural body hair growth and I'm also balding. For my knowledge this shouldn't be happening with such low DHT levels. Could my receptors be over sensitive or something? I also tried finasteride for hair loss. It worked worse than minoxidil and during the treatment I got headaches from my orbitofrontal cortex and my semen was all wierd. Sides got better after the treatment, although I believe I have even lower DHT levels now; seems like I have slight gynecomastia now etc.

Hair loss and isotretinoin go hand in hand. It is after all chemotherapy , highly toxic to the human body.

Caeruloplasmin 0.22 ( 0.15 0.33 ). Don't have Wilson's disease and don't have a copper issue.

My liver is still abnormal though in that it's fatty and my Cholesterol still too high. Is it because I take too many supplements, who would know!!??

Moving forward, more liver flushes, more mindful eating, slow down eating and do more exercise in general and wait for Roche to work on a cure ( I'm joking of course - as if that's ever going to happen )

I had the most comprehensive Gut Analysis that I know of - not one parasite detected!!!

I just have to work on my reflux issue.

http://forum.bodybuilding.com/showthread.php?t=146955103

I don't feel so bad now this guy did seven rounds of tan and is still alivelol ..... and so I think a small dose is survivable .

21 hours ago, blackfox01 said:

I quit finasteride and recovered. Then i smoked weed and crashed hard with PFS. Its def a 5Ari.

Cannabis actually contains quite a bit of beta-sitosterol. It is believed to be the pharmacologically active phytochemical in saw palmetto responsible for DHT-lowering effects. One of the guys who used to post on here, Crank92, mentioned going through a worsening of PFS-like symptoms after vaporizing cannabis, followed by a noticeable improvement in symptoms a few days later. He said he did this repeatedly and believes it lead to lasting improvements.

On 7/11/2016 at 8:14 PM, anonyy said:

I don't know why you focus on DHT, if i remember it's not3a-diol G that you should look into?

By the way i just looked into it and zinc raise DHT, not reduce it (maybe it inhibit only one type or 5AR?):
http://www.ncbi.nlm.nih.gov/pubmed/8613886
http://www.ncbi.nlm.nih.gov/pubmed/7271365

Libido issue is adrenal related, and prostate + testis also ofc, try some glandular's you'll see. Anyway you can't test for enzymes or receptors, and can't do anything about it except let the body fix it itself, and apparently there is no issue with 5ARsince someone posted their DHT results and it was high. Still searching the wrong way for solutions.. You don't have issues with receptors 10 years after accutane, and you don't need to take accutane to have libido issues. Specific treatment about accutane is just about restoring homeostasis between vitamin A & D, can't do anything more, the rest is standard physiology and so detox & damage repair.

Do you recommend any specific type of glandulars or would any from, say, Amazon work?

Pretty sure accutane ruined my eyesight. Well not ruined but i always had perfect vision until i was on accutane, then things farther away got blurry like reading a clock or whatever. Still like that too, and has gotten worse. Have been thinking lately that i might need glasses soon... all because of accutane.

Wow look

. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639958/

a guy got this from propecia. He was suicidal over hyper androgenic.

Many guys with pfs felt hyper androgen right before the crash. Seems like this lady never crashed.

take note at how her hormones were normal. Indicating a receptor issue.

4 hours ago, blackfox01 said:

Wow look

. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639958/

a guy got this from propecia. He was suicidal over hyper androgenic.

Many guys with pfs felt hyper androgen right before the crash. Seems like this lady never crashed.

take note at how her hormones were normal. Indicating a receptor issue.

Hey guys, may I jump in this thread... My boyfriend took accutane at only 20 or 30 mg for about a month and a half 10 years ago and he had a suicide attempt, out of the blue. He said he felt like everything gwas bleak and hopeless and it was like he was in a black cloud. He also has IBS issues, dry eyes and joint problems to this day, he will be OK for a while then one of his hips or his back will lock up.
I also know a guy who took Chantix to quit smoking and hanged himself.
I'm sorry you all are going through this crap! I never took accutane but I took antibiotics and got freaked out over possible side effects. These doctors are giving out poisons without explaining ( or even knowing ) the potential long term problems. Meanwhile they tell you nothing about nutrition, vitamin deficiencies and exercise. Just...thoroughly pissed off.

On 7/12/2016 at 4:40 AM, Pido said:

I've had DHT tested and result was 1.09 nmol/l (1.03 - 2.92). I got unnatural body hair growth and I'm also balding. For my knowledge this shouldn't be happening with such low DHT levels. Could my receptors be over sensitive or something? I also tried finasteride for hair loss. It worked worse than minoxidil and during the treatment I got headaches from my orbitofrontal cortex and my semen was all wierd. Sides got better after the treatment, although I believe I have even lower DHT levels now; seems like I have slight gynecomastia now etc.

I know many women have normal androgen levels but are very sensitive to them. Why not men too?

14 hours ago, sh1234 said:

Pretty sure accutane ruined my eyesight. Well not ruined but i always had perfect vision until i was on accutane, then things farther away got blurry like reading a clock or whatever. Still like that too, and has gotten worse. Have been thinking lately that i might need glasses soon... all because of accutane.

http://www.danielvitalis.com/rewild-yourself-podcast/building-better-vision-jake-steiner-96
Follow Jake Steiner's advise to repair your vision. It's not permanent.
Also, eat pastured liver once a week if you suffer any night vision problems.

17 hours ago, TrueJustice said:

I had the most comprehensive Gut Analysis that I know of - not one parasite detected!!!
I just have to work on my reflux issue.

Parasites have auto-lysis capabilities. They disappear in your stool after about 15 min.
Just assume you have parasites.
Also, if you suffer from reflux and are eating mindfully, you definitely have a clogged liver.
You need to be doing many liver flushes (at least 15) and tons of coffee enemas.

I suggest everyone here look into Nicholas Gonzalez' work on how diet and individual nutrients impact autonomic function. That may lead us closer to a cure. I've had to relearn everything I thought I knew about nutrition. His lectures are phenomenal. My favorite is the 2009 lecture done in london.
http://www.newspringpress.com/lectures.html

Books to read: Francis Pottenger's book on the autonomic nervous system called Symptoms of Visceral Disease.
Ernst Gellhorn's books on autonomic dominance (really technical)
Sir Roger Bannister's book on autonomic failure.

2 hours ago, yetanotheraccutanevictim said:

http://www.danielvitalis.com/rewild-yourself-podcast/building-better-vision-jake-steiner-96
Follow Jake Steiner's advise to repair your vision. It's not permanent.
Also, eat pastured liver once a week if you suffer any night vision problems.

Parasites have auto-lysis capabilities. They disappear in your stool after about 15 min.
Just assume you have parasites.
Also, if you suffer from reflux and are eating mindfully, you definitely have a clogged liver.
You need to be doing many liver flushes (at least 15) and tons of coffee enemas.

I suggest everyone here look into Nicholas Gonzalez' work on how diet and individual nutrients impact autonomic function. That may lead us closer to a cure. I've had to relearn everything I thought I knew about nutrition. His lectures are phenomenal. My favorite is the 2009 lecture done in london.
http://www.newspringpress.com/lectures.html

Books to read: Francis Pottenger's book on the autonomic nervous system called Symptoms of Visceral Disease.
Ernst Gellhorn's books on autonomic dominance (really technical)
Sir Roger Bannister's book on autonomic failure.

Tests on gut indicate I don't have anything sinister going on with parasite infection. The whole reason for my recent Gastroscopy was to find out if there was any nasty infection, with my symptoms of fatigue and light sensitivity the doctor thought there might be. Do I still have some candida? probably but I don't think he was looking for that. Minor parasites I'll have deal with in my own way...,

This doesn't mean I don't have leaky gut or SIBO as far as I know of so I'll be discussing this in my follow up appointment with Dr.

Currently doing my 5th Liver flush this week so I still have a way to go in reaching 15 of them.

One thing my gut test did indicate was an ulcerative Oesophagus- hence why I need to curb the acid reflux issue.

19 hours ago, sh1234 said:

Pretty sure accutane ruined my eyesight. Well not ruined but i always had perfect vision until i was on accutane, then things farther away got blurry like reading a clock or whatever. Still like that too, and has gotten worse. Have been thinking lately that i might need glasses soon... all because of accutane.

You don't need glasses, i had to use some but now i can't see with them. Avoid sodas, high refined/white sugar food, verify you don't have a vitamin A deficiency and maybe take some chromium and you'll be fine.

Cannabis is a strong autonomic system & so adrenal depressant, it force them to work harder, it's a stimulant but the effect won't last. Experienced it myself.