Hello Everyone,

 

Short Version: Test results are in, I have low DHEA. My levels are at an abysmal 39 (they should be at 1500). I'm doing to start DHEA treatment ASAP and see if that affects my accutane symptoms. (Neurofeedback, covered by my insurance has helped correct all the cognitive-fatigue-emotional symptoms that I've had since taking this drug). I will keep people updated on my progress. Has anyone else taken the Rhein 24 Urine test? It assess subcomponents of the endocrine system that most blood-tests do not.

 

Best!

~A2

 

Recap/Long Version: I took accutane in 1998 and again in 2002. (Worst. Idea. EVER.) In March 2013, I underwent a QEEG brain scan for $200 (not covered by insurance) and I was diagnosed with diffuse levels of theta activity across my cortex (this corresponds to cortical idling, moodiness, brain fog, fatigue) as well as high beta in the back of my brain (which corresponds to anxiety). My insurance covered Neurofeedback therapy which completely corrected these cognitive symptoms. Physical symptoms remained.

 

In August 2015, I met with Dr. C in Lansing, MI who has treated and tracked many patients who believe they have had adverse reactions to accutane. (PM me if you'd like his contact info- many others users have cited him on this forum). While I had completed the usual rounds of hormonal bloodwork, which were all normal, he strongly, strongly, strongly advised me to do a Rhein 24 Hour Urine test (based out of a laboratory in Portland, OR). In his opinion, this is the ONLY test that matters. The Rhein test has been invaluable to identify hormonal abnormalities in men with sexual dysfunction. The test was easy to complete- I received it in the mail, did it at home, and mailed it to Portland, OR the next day. Three hours ago, Dr. C and I discussed the results of the Rhein Urine panel over the phone. All of my hormonal indicators were normal except for my DHEA which was appalling low at 39- which corresponds with many of my physical symptoms.

 

Of course, it's not possible to say whether accutane caused or augmented low DHEA. However, the Rhein panel is the first time I came across a good biomarker for accutane-related damage after several urologists and endocrinologists dismissed my symptoms. 5 Questions:

 

-Has anyone else completed the Rhein 24 Urine panel? (It costs a few hundred dollars- partially subsidized by my insurance, the rest was paid by my flexible health savings account)

-Has anyone else been diagnosed with low DHEA?

-Has anyone else been treated for low DHEA? If so what are the results?

-Has anyone undergone a QEEG brain scan? (costs $200).

-Has anyone undergone a SPECT imaging brain scan? (costs $3,000-$4,000).

 

In order to build a stronger case about the dangers, and the need to repair long term damage, from accutane, it is essential to identify abnormal indicators. I'm very curious if other people would get tested for the Rhein 24 Hour Urine test if we begin to see a set of common patterns related to accutane damage. (Perhaps there are 4 or 5 constellations of symptoms).

 

Not many people have spoken to the efficacy of Neurofeedback, or the Rhein test, so I wanted to make sure I put those 2 interventions out here for the public record. Best of luck!

What exactly did the Neurofeedback involve, I'm assuming a course of medication, if so what?

Interesting about the DHEA. One thing that definitely helps lesson my brain fog (and also lessons effects of ED/loss of libido slightly) is pine pollen which contains a number of bio-available androgens - one of them being DHEA.

I've generally been taking about a tea spoon of the pollen per day. Taking 3-4 for a few weeks really helped things, but then I started getting symptoms of excess estrogen like sensitive nipples. I may consider upping the dose whilst taking a natural aromatse inhibitor, but haven't done so yet.

Sounds interesting what you had done. I want one of those brain scans but figure I'll hang in here for the next few years. Currently on day 2 of another fast. Let's see how long I can do this working 56 hour weeks in a factory.

Libido problem is just tired surrenals & nervous system by global acidity/toxicity & lack of nutrients absorption (cause the cells environment is too congestioned), nothing to do with accutane (but caused by it). It can be an excess of acidity/toxicity localized in the penis too. Since i cured myself from "accutane" my libido increased but the main thing is the sensation/pleasure in that area, who are 10 times stronger than before. Before i had orgasm but with no sensation, i feeled my penis in a strange cold/void area. Thing i noticed too is the structure of the penis, who is more "compact", don't know how to explain it. I put everyday castor oil on my penis & testicule, i find it very very helpful, this oil as an ability to stimulate the immune system & starting a detoxifying process very quickly. I saw it since after my first 3days of application i had my testicule skin who fell, typicaly a detoxification reaction (castor oil is just an oil, nothing irritant who can "kill" the skin directly). My libido & sensation increased even more after doing this. Jelq exercise seems to help detoxification + enhancing the structure too. But it's not magical, if you don't fix your general toxicity, your surrenals + nervous system will still be weakened and you won't have so much improve.

EDIT: I'm posting this a second time in the hope to receive more replies.

I signed up specifically to react to this post from 2013.

My story:

I have had 7 accutane courses from the ages 14 - 26 and am currently recently my eight course (yes. eight. trust me when I say its NEEDED). The six or seventh course (can't remember) hit me very very hard in the libido and erectile dysfunction depertment. I had a long term relationship at the time, so it was very obvious for me to notice. To put it bluntly: before I would have instant erections and would have a hard time holding myself from coming, since then, I have to make a concious effort to get erections and a concious effort through focussing to come during sex.

It is like there is a knot between my brain and my penis, like it simply does not work anymore.

I am very very desperate to fix my cure, it has now been SIX years and my libido is still fkn trashed. Doctors in my country can't help me. I have done blood tests, I am fine.

Help me people. This problem is not in my head. I cannot even properly masturbate and when having sex I have a very hard time keeping it up and coming.

I am currently looking into jelqing but I'm open to any kind of advice.

Thanks

 

Libido problem is just tired surrenals & nervous system by global acidity/toxicity & lack of nutrients absorption (cause the cells environment is too congestioned), nothing to do with accutane (but caused by it). It can be an excess of acidity/toxicity localized in the penis too. Since i cured myself from "accutane" my libido increased but the main thing is the sensation/pleasure in that area, who are 10 times stronger than before. Before i had orgasm but with no sensation, i feeled my penis in a strange cold/void area. Thing i noticed too is the structure of the penis, who is more "compact", don't know how to explain it. I put everyday castor oil on my penis & testicule, i find it very very helpful, this oil as an ability to stimulate the immune system & starting a detoxifying process very quickly. I saw it since after my first 3days of application i had my testicule skin who fell, typicaly a detoxification reaction (castor oil is just an oil, nothing irritant who can "kill" the skin directly). My libido & sensation increased even more after doing this. Jelq exercise seems to help detoxification + enhancing the structure too. But it's not magical, if you don't fix your general toxicity, your surrenals + nervous system will still be weakened and you won't have so much improve.

 

EDIT: I'm posting this a second time in the hope to receive more replies.

 

I signed up specifically to react to this post from 2013.

 

My story:

I have had 7 accutane courses from the ages 14 - 26 and am currently recently my eight course (yes. eight. trust me when I say its NEEDED). The six or seventh course (can't remember) hit me very very hard in the libido and erectile dysfunction depertment. I had a long term relationship at the time, so it was very obvious for me to notice. To put it bluntly: before I would have instant erections and would have a hard time holding myself from coming, since then, I have to make a concious effort to get erections and a concious effort through focussing to come during sex.

 

It is like there is a knot between my brain and my penis, like it simply does not work anymore.

 

I am very very desperate to fix my cure, it has now been SIX years and my libido is still fkn trashed. Doctors in my country can't help me. I have done blood tests, I am fine.

 

Help me people. This problem is not in my head. I cannot even properly masturbate and when having sex I have a very hard time keeping it up and coming.

 

I am currently looking into jelqing but I'm open to any kind of advice.

 

Thanks

Hi Toosje,

when you scroll through this entire thread, you will realize, that even after years no one has found a solution for the permanent side effects of accutane. People here can not help you just because they are no even able to help themselves.

The only advise I can give you is: Stop your accutane treatment now.

You are saying, it is needed. But why? You had 7 accutane courses already and it did not heal you. What do you expect from your 8th course? You only will make things worse.

 

Libido problem is just tired surrenals & nervous system by global acidity/toxicity & lack of nutrients absorption (cause the cells environment is too congestioned), nothing to do with accutane (but caused by it). It can be an excess of acidity/toxicity localized in the penis too. Since i cured myself from "accutane" my libido increased but the main thing is the sensation/pleasure in that area, who are 10 times stronger than before. Before i had orgasm but with no sensation, i feeled my penis in a strange cold/void area. Thing i noticed too is the structure of the penis, who is more "compact", don't know how to explain it. I put everyday castor oil on my penis & testicule, i find it very very helpful, this oil as an ability to stimulate the immune system & starting a detoxifying process very quickly. I saw it since after my first 3days of application i had my testicule skin who fell, typicaly a detoxification reaction (castor oil is just an oil, nothing irritant who can "kill" the skin directly). My libido & sensation increased even more after doing this. Jelq exercise seems to help detoxification + enhancing the structure too. But it's not magical, if you don't fix your general toxicity, your surrenals + nervous system will still be weakened and you won't have so much improve.

 

EDIT: I'm posting this a second time in the hope to receive more replies.

 

I signed up specifically to react to this post from 2013.

 

My story:

I have had 7 accutane courses from the ages 14 - 26 and am currently recently my eight course (yes. eight. trust me when I say its NEEDED). The six or seventh course (can't remember) hit me very very hard in the libido and erectile dysfunction depertment. I had a long term relationship at the time, so it was very obvious for me to notice. To put it bluntly: before I would have instant erections and would have a hard time holding myself from coming, since then, I have to make a concious effort to get erections and a concious effort through focussing to come during sex.

 

It is like there is a knot between my brain and my penis, like it simply does not work anymore.

 

I am very very desperate to fix my cure, it has now been SIX years and my libido is still fkn trashed. Doctors in my country can't help me. I have done blood tests, I am fine.

 

Help me people. This problem is not in my head. I cannot even properly masturbate and when having sex I have a very hard time keeping it up and coming.

 

I am currently looking into jelqing but I'm open to any kind of advice.

 

Thanks

 

Hi Toosje,

 

when you scroll through this entire thread, you will realize, that even after years no one has found a solution for the permanent side effects of accutane. People here can not help you just because they are no even able to help themselves.

 

The only advise I can give you is: Stop your accutane treatment now.

 

You are saying, it is needed. But why? You had 7 accutane courses already and it did not heal you. What do you expect from your 8th course? You only will make things worse.

 

 

Appreciate the reply. I'm indeed going to come off this course, seeing all the cases in this thread...

Althougth there is no definite cure, did anybody try Jelqing or other penis excercises for their accutane induced ED?

I'm sure they've tried toosje. Jelqing isn't some new theory being thrown about. It's been around the internet since the 90's. You need to consider what we are trying to tell you. Once you have been affected negatively by Accutane...you are in the process of Palliative care. There is no solution at the moment.. We are racking our brains trying to figure out what went wrong.

This new "female viagra" (it is marketed as a libido pill) is interesting. It messes with the 5-HT1A and 5-HT2A receptors affecting dopamine and norepinephrine levels. Probably would do nothing for us, and I have no clue how safe it is. Give it a look into, though- its called flibanserin (trade name addyi) and it is getting a lot of media attention. It is not marketed towards males, but it is worth researching.

 

(Neurofeedback, covered by my insurance has helped correct all the cognitive-fatigue-emotional symptoms that I've had since taking this drug).

 

I discovered this treatment online during a research binge, but had not heard whether it was efficacious or not. That is very good to hear!

 

I definitely recommend having cortisol/DHEA and all related hormones checked if you have physical symptoms related to libido/dysfunction. Thank you for this information and please do keep us updated on your progress as you undergo DHEA treatment.

 

Cheers

I'll certainly keep everyone updated here. It's worth noting that after 12 years of doing periodic bloodwork (which always came out as normal) I was able to identify abnormal biomarkers via 1. A brain mapping Quantitative Electroencephalography (QEEG) prior to do neurofeedback and 2. The Rhein 24 hour urine panel. Cheers!

 

Hello Everyone,

 

Short Version: Test results are in, I have low DHEA. My levels are at an abysmal 39 (they should be at 1500). I'm doing to start DHEA treatment ASAP and see if that affects my accutane symptoms. (Neurofeedback, covered by my insurance has helped correct all the cognitive-fatigue-emotional symptoms that I've had since taking this drug). I will keep people updated on my progress. Has anyone else taken the Rhein 24 Urine test? It assess subcomponents of the endocrine system that most blood-tests do not.

 

Best!

~A2

 

Recap/Long Version: I took accutane in 1998 and again in 2002. (Worst. Idea. EVER.) In March 2013, I underwent a QEEG brain scan for $200 (not covered by insurance) and I was diagnosed with diffuse levels of theta activity across my cortex (this corresponds to cortical idling, moodiness, brain fog, fatigue) as well as high beta in the back of my brain (which corresponds to anxiety). My insurance covered Neurofeedback therapy which completely corrected these cognitive symptoms. Physical symptoms remained.

 

In August 2015, I met with Dr. C in Lansing, MI who has treated and tracked many patients who believe they have had adverse reactions to accutane. (PM me if you'd like his contact info- many others users have cited him on this forum). While I had completed the usual rounds of hormonal bloodwork, which were all normal, he strongly, strongly, strongly advised me to do a Rhein 24 Hour Urine test (based out of a laboratory in Portland, OR). In his opinion, this is the ONLY test that matters. The Rhein test has been invaluable to identify hormonal abnormalities in men with sexual dysfunction. The test was easy to complete- I received it in the mail, did it at home, and mailed it to Portland, OR the next day. Three hours ago, Dr. C and I discussed the results of the Rhein Urine panel over the phone. All of my hormonal indicators were normal except for my DHEA which was appalling low at 39- which corresponds with many of my physical symptoms.

 

Of course, it's not possible to say whether accutane caused or augmented low DHEA. However, the Rhein panel is the first time I came across a good biomarker for accutane-related damage after several urologists and endocrinologists dismissed my symptoms. 5 Questions:

 

-Has anyone else completed the Rhein 24 Urine panel? (It costs a few hundred dollars- partially subsidized by my insurance, the rest was paid by my flexible health savings account)

-Has anyone else been diagnosed with low DHEA?

-Has anyone else been treated for low DHEA? If so what are the results?

-Has anyone undergone a QEEG brain scan? (costs $200).

-Has anyone undergone a SPECT imaging brain scan? (costs $3,000-$4,000).

 

In order to build a stronger case about the dangers, and the need to repair long term damage, from accutane, it is essential to identify abnormal indicators. I'm very curious if other people would get tested for the Rhein 24 Hour Urine test if we begin to see a set of common patterns related to accutane damage. (Perhaps there are 4 or 5 constellations of symptoms).

 

Not many people have spoken to the efficacy of Neurofeedback, or the Rhein test, so I wanted to make sure I put those 2 interventions out here for the public record. Best of luck!

 

What exactly did the Neurofeedback involve, I'm assuming a course of medication, if so what?

 

Interesting about the DHEA. One thing that definitely helps lesson my brain fog (and also lessons effects of ED/loss of libido slightly) is pine pollen which contains a number of bio-available androgens - one of them being DHEA.

 

I've generally been taking about a tea spoon of the pollen per day. Taking 3-4 for a few weeks really helped things, but then I started getting symptoms of excess estrogen like sensitive nipples. I may consider upping the dose whilst taking a natural aromatse inhibitor, but haven't done so yet.

Hey, no meds, the acutane experience, as well as a bad experience with adderall in 2011, has made me highly skeptical of relying on pharmaceuticals to get me out of a problem that pharma got me into.....unless there are no other options. The appeal of using NF to address cognitive side effects of accutane, including fatigue, was appealing to me because:

1. NF has little to no side effects

2. NF has a research base - and strong base to improve chronic fatigue, anxiety, depression, and cortical idling

3. NF's benefits are quantifiable

4. NF can be done under the supervision of a doctor.

Again, I hate tacking pills if I can avoid it and I hate experimenting with treatments without coordination with an MD or a PsyD. Also the NF clinic was a block from my work so I could go at my leisure. (It takes most people 40-60 sessions to complete treatment; and each session takes 30-45 minutes).

Here's the official definition of Neurofeedback the NF Research association website: "Like other forms of biofeedback, [NF] uses monitoring devices to provide moment-to-moment information to an individual on the state of their physiological functioning. The characteristic that distinguishes [NF] from other biofeedback is a focus on the central nervous system and the brain. Neurofeedback training [NF] has its foundations in basic and applied neuroscience as well as data-based clinical practice. It takes into account behavioral, cognitive, and subjective aspects as well as brain activity.

NFT is preceded by an objective assessment of brain activity and psychological status. During training, sensors are placed on the scalp and then connected to sensitive electronics and computer software that detect, amplify, and record specific brain activity. Resulting information is fed back to the trainee virtually instantaneously with the conceptual understanding that changes in the feedback signal indicate whether or not the trainee's brain activity is within the designated range. Based on this feedback, various principles of learning, and practitioner guidance, changes in brain patterns occur and are associated with positive changes in physical, emotional, and cognitive states. Often the trainee is not consciously aware of the mechanisms by which such changes are accomplished although people routinely acquire a "felt sense" of these positive changes and often are able to access these states outside the feedback session.

NFT does not involve either surgery or medication and is neither painful nor embarassing. When provided by a licensed professional with appropriate training, generally trainees do not experience negative side-effects. Typically trainees find NFT to be an interesting experience. Neurofeedback operates at a brain functional level and transcends the need to classify using existing diagnostic categories. It modulates the brain activity at the level of the neuronal dynamics of excitation and inhibition which underly the characteristic effects that are reported.

I live in Chicago, and there are 10 doctors who offer NF here- all of them are pretty booked especially since insurance starting covering this treatment The findings were done at my Doctor's office (there are ten clinics in Chicago that offer NF) and while the QEEG was not covered by my insurance (it cost me $200) all follow-up visits were (I have Aetna health insurance in the United States). I started with an initial brain mapping called a Quantitative Electroencephalography (qEEG). This entails sitting still while sensors are placed on my head (20 minutes eyes open and then 20 minutes eyes-closed). The sensors measure electrical activity taking place in my cortex and it measures brain waves from a speed of 0 Hz to 45 Hz. My results were sent to Neurologist who compared my brainwave findings to a population sample and produced a 10 page report for my doctor and I to review. It showed the brainwave activity at 19 sites throughout my cortex. I found I have high levels of theta waves (slow moving brain waves) across my prefrontal cortex, sensorimotor strip, and temporal lobes. I completed 40 sessions (4 times a week during my lunch break at work) each no more than 30 minutes were I completed NF training. The training entailed sitting in front of a computer screen and playing a spaceship video game called, "BioExplorer" in which a spaceship speeds up whenever my cortex operates at SMR/Low Beta Wave levels (12-15 Hz) and the spaceship slows down when my brain is below 12 Hz or above 15 Hz. I HATED this program when I started because it was so difficult for me to get the damn spaceship to move! After 8 sessions, I got the hang of it and it's been great ever since. My anxiety, focus, attention, depression, and fatigue have greatly improved since doing this. I'll probably get a QEEG every year as a diagnostic tool.

Here's a quick crash course in brainwaves!

0-3 Hz Delta Waves

4-7 Hz Theta Waves

8-11 Hz Alpha Waves

12-15 Hz SMR/Low Beta Waves

15-18 Hz Medium Beta Waves

18-36 Hz High Beta Waves

36-45 Hz Gamma Waves

Again, I'm not sure if everyone's results will improve with NF but if you live near a provider and you have insurance coverage, I highly urge you to give it a shot!

~A2

Has anyone here tried Mepacrine? It's supposed to be useful for treating the long term musculo-skeletal and facial flushing side effects.

Has anyone here tried Mepacrine? It's supposed to be useful for treating the long term musculo-skeletal and facial flushing side effects.

I have not tried this myself. But a friend of mine, who is also suffering from long term accutane sides, took it for his facial flushing. And he reported terrible depression and stopped it. He said, he never felt so terrible in his life.

Wow! I had no idea that Mepacrine could cause depression as it's not a listed side effect. Do you know what dose he took and for how long?

Wow! I had no idea that Mepacrine could cause depression as it's not a listed side effect. Do you know what dose he took and for how long?

He took it only for a couple of days. I don't know about the dose though.

My theory, that our problem is low bioaviable (free) IGF-1. If you look the studys (Accutane and IGF-1) you can see that the drug has LOWERED SIGNIFICANTLY our IGF-1 and IGFBP 3 (a binding protein that makes it more powerful in the body). Make tests for NOT ONLY IGF-1 but also for IGFBP 3. There are other 5 binding proteins that makes the hormone unaviable for our bodies. IGF-1 is the most potent 5 alpha reductase type one (The type found mostly in the Face sebaceous glands) INDUCER. We have low active DHT because the type 1 5 alpha reductase was inhibited. If there is no type 1, there is nothing that can convert to type 2 (the 5 alpha reductase found in sexual organ).

Now you can read many bad things on the net about IGF-1 (causes cancer...) Yeah this could be true but only in high quantities. Low levels are not good too. You should be in the top range.

Another sign to me that I am deficient is, that my hands are very small for a man. OK in SHORT: NOt testosterone induces 5 alpha redcutase but IGF-1 does.

God bless you people stay strong

My IGF-1 tested at the top of the normal range and my DHT was in the mid normal range. I took Accutane for 2 years! Go figure!

Hey guys i think a year ago I was 1 year post my accutane treatment and I postet that my life is fucked and stuff like that. I'm 19 rn and figured out some things. Don't hate on me I'm in a similar situation than most of us, but think about that my friends.

We had acne. Why we been taking accutane. Cause our life sucked with acne. And let's be real to ourselves. Acne is shit. I was 17 had moderate acne for 3 years I wanted accutane really bad I had a bad doc, that doesn't wanted me to be on it. But it was like I don't had enough life experience to think about consequences or real pain, only had it as a child so I didn't remember fully . So me probably most of us took it to have a better life. Which is really possible. Okay maybe we're the few unlucky ones that got got sides, maybe that stuff would come up even tho without it. We don't know. only thing that us taking accutane is saying that were positive people in general that think of a good outcome. I was an semi pro athlete. I had to stop because of joint pain. I'll be doing everything to.come back to my sport. cause you know what life is too short and the thing is cause of accutane we denie ourselfes to be happy. thats the thing. shit happens to people. nobody forced us to take accutane even we don't know about it. People experiencing mistakes that are worse than ours. Some guys I know been dying cause one of them was not driving right. What about them, their life is fucked and I hope their in heaven. So my brothers we have to man up. Accutane is fucking with us. I was diagnosed with middle depression cause of that. They told me to.take meds but I denied it and forced me.to. do stuff that makes me feel better. DEPRESSION is the biggest thing we have to correct in this blog for most of us. That's it. And I'm sorry but I think this forum sucks for the most part. Everybody that's in my age and going trough same try to get through it it'll get better no doubt. My libido is still low but getting better. So the "Men" here in this blog that tryna help people that are it the same situation you don't do shit for them to feel better, this blog just took me more in it. My advice for all in this blog is. Treat Depression; that's number 1. Don't denie it. It'll make things way worse. I feel different since accutane and have my down days but don't let these things take over your life. It'll get better. Second is your body needs time to help yourself. But if your stressed all the time cause of accutane+ depressed= no time for body to regenerate.Plus for some it'll cause feeling bad and worsen body pains. 1 advice. TRY YOGA, MEDIATING. We have two brains. One is responsible for things like action, weight lifting, adrenalin,all active things. The other is responsible for healing and stuff like that. So my advise if you feel like your in your head most time and not in real.life. Do Things that let you feel your body. Let someone massage you, go to the sauna, learn mediation and go.to a good yoga school on a regular basis, do regular stretching if you want with binaural beats. I promise after those things you ll sleep good your body has time to heal and calms down and gets balanced. PLUS that try sports. If you can try Leigh weight lifting it ll support your joint. Before workout do dynamic stretching. Go jogging. If that's not possible try swimming or by cycling. I started with swimming now I'm back to leight calisthenics. Adapt to your situation instead of acting a little kid and only complaining about it, popping some pills, sitting and feeling bad about yourself. Ive been in the same I missed lifetime,.lost health, and build problems..... So instead of saying why me im.too young for this. be like ok I experience this shit. still im me. I'm getting stronger even all others don't belive us. It makes us stronger than most, if we get though it. Supplements and good eating is good Thing I can recommend which helped me or it been time going by is collagen hydrolysate. It's great for joints digestion, and mental health. Buy it if you have similar probs and give it a year of daily use. All takes time. There's no quick fix, but the main thing it's getting better bros . People that have strong digestion can try gelatine powder, but for me it is killing my digestion. Rn I tried it a week,.and my digestion is going crazy like the months after accutane. So be careful and try hydrolysate maybe it'll help you like it did for me. 2 thing is don't be like naaaa I will live 100% healthy , cause of that you ll maybe miss good times. If your post tane and your with friends they wanna drink some DO IT. You ll have fun. Smoke some weed on a good party. It's A1. Doing some hookah or eating some fast food it's okay

Cause you know most people here take organic stuff way to important. Our body and our brain is connected. Both influences each other. So feeling good= better feeling in general= less depression= Less body pains and feeling tired and sick. I was with a mental health doc after the sides pulled me down and the inet making it worse. She was like boy I think your brain chemistry is out of balance you need some medications. You have to acting depression symptoms. But I was like I'll want to wait. Do some taking therapy instead. It can also change brain physiology. I wasn't doing it and figured stuff out for myself. Bless god You know where thinking causes a body answer. You think of a lemon. Your mouth answers. It's same with negative emotions and thinking. So be positive. There is a strong side. Let it come though. There's one easier to.do.sayimg you life sucks I don't wanna go out rn or work and sit alone and feel bad. The harder thing to do is going out doing things out of your comfort zone. Do those and let this side win even it feel soo fucking shit and in the end you feel right. Cause we're feeling bad cause deep.down we know the way we acting is wrong. Plus I feel most of us are gens rally unhappy with their life. I don't want to attack some but it's my opinion. Do we have a job we like? Do we have friends we like ? Maybe no women ? Family Struggle or.other stuff. So come guys let's make it easy and blame eyerything on a drug. Naaa Let's man up bros:). I feel like we need this on that blog cause most of us acting like pussys me included a few time ago. Last sentence: My granddad was in war 2. They stole 5 years of his life, took good friends/family, he was hurt, he was so I'll he nearly died cause of an illness.His whole joints were swollen. He had cancer 4 times. Still he's a real MAN. He going through all of this without complaining, made his way from rack.to riches, helped his fam, Nice to all people, respected, 92 years old and healthy with a smile on his face and caring for others, even though he was confronting dead often in his life. So guys we have the choice. I myself feel bad and my mood still swings bacause of my joint pain, sexual probs that appear sometimes. But man's and girls Maybe everything will be fine in a year 2,3,4,5. I'm working on getting better and even tho I lack sometimes I know that I'm doing it at least we should try it for our family's cause you know what, they are hurted when they see us like that. And fams everything So Endure some and Give them peace I could go on for hours but I'll need to sleep. Hope I'll help some guys here. The guys that hating it's okay I know you just do it because you feel attacked in your comfort zone. Grow up!!!! I'm not saying these words cause I want to hurt those that felt like me it's just advice. Cause accepting is all we can do.Maybe it is accutane maybe it's life maybe it's us genetics. We don't know. Live live the fullest and don't forget to man up. We only have one and need to try best to make those we love and love us to have a happy life. If you want more advice just text me. Maybe it'll take some time to answer cause I'm not that often here cause it's making us more depressed than we already are. Get it out of your head and do stuff you enjoy;) Praise all people here I wish best for you all

wat

Sry my inet sucks it send it 4 times

Accutainted4ever,

do you have tested only IGF-1 or both IGF-1 and IGFBP-3?

Only the free IGF-1 matters. It's like with the DHT test. My DHT was high on the test, but how could DHT be high if SHBG is through the roof?!

DHT binds strongly to SHBG. If you the option test for 3 alpha diol G level (it shows only the active DHT, because its a metabolite of it). Natural strategies to increase IGF-1 activity is Casein Protein mostly found in milk (because of the problem that milk is filled with bad things too, I take a Casein supplement).

http://www.ncbi.nlm.nih.gov/pubmed/20128787

Here the study on IGF-1.

Here the study of IGF-1 effect on 5 alpha reductase.

http://www.ncbi.nlm.nih.gov/pubmed/8344190

IGF-1 also activates Androgen receptors.

There is a drug calles Mecasermin rinfabate (syntetic but identical IGF-1 found in Human body)

Have you experienced any improvements of your sides since you take Casein supplement?

timati2340 I really admire your positive outlook on things, I was like you for the first years, but then well after some time living like this you just get bitter I guess.

Roland1968, I have noted some good effects specially in the first days. Good Sleep, Anxiety much better. I have two pimples now on the Face. The strange thing is, that in the first days I was waking up with morning wood.

Other people considering Acutane might be interested in our experience with the drug:

http://www.iodine.com/drug/accutane/reviews

^ It's only a couple minute process to leave a review on this site.

Just a heads up. I have a friend who is also taned out. Aside from all of our similarly related symptoms (which he has also), he's had to deal with permanent eye discomfort and severe irritation for years, and has been to several ophthalmologists to no avail. He recently saw one that prescribed him eye drops of the fluoroquinolone type (I guess her dumb ass thought he had some type of bacterial infection). He was a bit skeptical but tried a single drop in one eye, just looking for relief. Anyways, he's now been to the emergency room twice over the past week with shortness of breath, tightness in his chest, as well as pain in his left arm, he also said he had some tremors which he described as the scariest thing ever. He's in a world of pain at the moment.

I've never heard of these types of drugs, but apparently from some internet searching they are bloody nukes in regard to fighting bacterial infections. These pharma companies are seriously taking the piss and having a laugh I'm starting to think.

Not trying to get philosophical here, or rant against pharma, just trying to warn you guys ahead of time. I don't know if it's a genetic thing, and we are susceptible, or what. But avoid fluoroquinolone's at all cost if you have bacterial issues.