What Is It?
This topical treatment is a combination of sodium sulfacetamide, which is a type of topical antibiotic called a sulfa antibiotic that helps stop the growth of acne bacteria, and sulfur, which may help dry and peel the skin as well as reduce acne bacteria.
It is usually applied 1-2 times a day.
Efficacy
Strength of Evidence
Average 81% reduction in acne after 11 weeks
Side Effects
Low-Medium
Low-medium side effects and adverse reactions
Acne.org's Real World Take
Not often used because it smells bad, colors the skin when applied, and can (rarely) lead to severe side effects. Limited evidence shows that it does significantly clear mild-to-moderate acne, but we need more research to know for sure how well it works.