Microneedling with Platelet-rich Plasma

Compare To Other Treatments

What Is It?

Microneedling devices puncture the skin with needles in an attempt to stimulate more collagen and elastin production. After this skin microneedling, platelet-rich plasma is applied to the skin. 

Platelet-rich plasma is extracted from the patient’s own blood just before the start of the treatment. Platelet-rich plasma contains high levels of growth factors, which help stimulate cells to produce collagen and elastin. 

This procedure is normally repeated up to 6 times in 1-month intervals, and you should see gradual results with each session. And after your last session, your skin should continue to improve.

Good or Excellent Response

Strength of Evidence
1
2
3
4
5
59% of patients achieved a good (>50%) or excellent (>75%) improvement in scarring after 4 sessions

Moderate Response

Strength of Evidence
1
2
3
4
5
83% of patients achieved at least a moderate (>25%) improvement in scarring after 4 sessions
▸ Based on These Clinical Studies & Trials
▾ Based on These Clinical Studies & Trials
  1. Ulfat, M. et al. To compare the efficacy of 35% glycolic acid along with micro-needling versus platelet rich plasma along with micro-needling in treatment of the acne scars. Journal of Pakistan Association of Dermatologists 33, 986–990 (2023).
  2. Sindhu, B., Naidu, C., Babu, S. & Teja, R. Microneedling vs microneedling with PRP in atrophic acne scars treatment. Journal of Cardiovascular Disease Research 14, (2023).
  3. Mubeen, S. et al. Comparison of outcome of microneedling with autologus platelet rich plasma verses microneedling with topical insulin in the treatment of post-acne atrophic scars. Journal of Pakistan Association of Dermatologists 33, 1461–1468 (2023).
  4. Khattab, F. M., Samir, M. A., El Khouly, S. S. & Atwa, E. M. Efficacy of Polycaprolactone Threads in Treating Atrophic Acne Scars: A Split-face Comparative Study. J Clin Aesthet Dermatol 16, 33–37 (2023).
  5. Khan, A. I., Aamir, S., Naseem, R. & Rasheed, J. Comparing the effectiveness of microneedling along with Platelet Rich Plasma versus microneedling alone in treatment of acne scars. Journal of Pakistan Association of Dermatologists 33, 1500–1507 (2023).
  6. Diab, N. A. F., Ibrahim, A. M. & Abdallah, A. M. Fluid platelet-rich fibrin (PRF) versus platelet-rich plasma (PRP) in the treatment of atrophic acne scars: A comparative study. Arch Dermatol Res (2022) doi:10.1007/s00403-022-02511-3.
  7. Albalat, W., Ghonemy, S., Saleh, A. & Elradi, M. Microneedling combined with botulinum toxin-A versus microneedling combined with platelet-rich plasma in treatment of atrophic acne scars: a comparative split face study. Arch Dermatol Res 315, 839–846 (2022).
  8. Nandini, A. S., Sankey, S. M., Sowmya, C. S. & Sharath Kumar, B. C. Split-face comparative study of efficacy of platelet-rich plasma combined with microneedling versus microneedling alone in treatment of post-acne scars. J Cutan Aesthet Surg 14, 26–31 (2021).
  9. Gupta, M., Barman, K. D. & Sarkar, R. A comparative study of microneedling alone versus along with platelet-rich plasma in acne scars. J Cutan Aesthet Surg 14, 64–71 (2021).
  10. Amer, A., Elhariry, S. & Al-Balat, W. Combined autologous platelet-rich plasma with microneedling versus microneedling with non-cross-linked hyaluronic acid in the treatment of atrophic acne scars: split-face study. Dermatol Ther 34, e14457 (2021).
  11. Sharma, S., Kaur, T. & Bassi, R. A split face comparative study to evaluate the efficacy of skin microneedling and platelet rich plasma (PRP) combination versus skin microneedling alone for treatment of post acne scars. Journal of Pakistan Association of Dermatologists 30, 449–455 (2020).
  12. Elfar, N. N. & Hasby, E. A. Efficacy and safety of plasma gel as a new modality in treatment of atrophic acne scars. Int J Dermatol 59, 620–626 (2020).
  13. Banker, K. A split face comparative study of microneeding with platelet rich plasma versus fractional CO2 laser with platelet rich plasma in management of atrophic acne scars. (2020).
  14. Porwal, S., Chahar, Y. S. & Singh, P. K. A comparative study of combined Dermaroller and platelet-rich plasma versus Dermaroller alone in acne scars and assessment of quality of life before and after treatment. Indian Journal of Dermatology 63, 403 (2018).
  15. Ibrahim, M. K., Ibrahim, S. M. & Salem, A. M. Skin microneedling plus platelet-rich plasma versus skin microneedling alone in the treatment of atrophic post acne scars: a split face comparative study. J Dermatolog Treat 29, 281–286 (2018).
  16. El-Domyati, M., Abdel-Wahab, H. & Hossam, A. Microneedling combined with platelet-rich plasma or trichloroacetic acid peeling for management of acne scarring: a split-face clinical and histologic comparison. J Cosmet Dermatol 17, 73–83 (2018).
  17. Yadav, D. C. K. et al. A comparative study of efficacy of micro-needling alone versus micro-needling with autologous platelet rich plasma in facial atrophic acne scars. International Multispecialty Journal of Health 3, 7 (2017).
  18. Ranjan, S., Gupta, R. S. & Gupta, S. A study of the efficacy of skin needling and platelet rich plasma in the treatment of acne scars. Nepal Journal of Dermatology, Venereology & Leprology 15, 17–23 (2017).
  19. Ibrahim, Z. A., El-Ashmawy, A. A. & Shora, O. A. Therapeutic effect of microneedling and autologous platelet-rich plasma in the treatment of atrophic scars: a randomized study. J Cosmet Dermatol 16, 388–399 (2017).
  20. Asif, M., Kanodia, S. & Singh, K. Combined autologous platelet-rich plasma with microneedling verses microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study. J Cosmet Dermatol 15, 434–443 (2016).
  21. Nofal, E., Helmy, A., Nofal, A., Alakad, R. & Nasr, M. Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study. Dermatologic Surgery 40, 864–873 (2014).
  22. Chawla, S. Split face comparative study of microneedling with PRP versus microneedling with vitamin C in treating atrophic post acne scars. J Cutan Aesthet Surg 7, 209–212 (2014).
  23. Fabbrocini, G. et al. Combined use of skin needling and platelet-rich plasma in acne scarring treatment. Cutis 24, 177–183 (2011).

Side Effects

Medium-High
Medium-high side effects and adverse reactions

Reviews

View All
0.0
0 Reviews

Relevant Forum(s):