Oral Retinoid
Reviews
3.9
2791 Reviews
Oral Retinoid
Efficacy
87%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Use with EXTREME CAUTION: Causes severe birth defects and fetal death.
Oral Retinoid
Side Effects
High
Oral Retinoid
Acne.org’s Real World Take
The nuclear option. It works reliably and provides long-term remission of acne, and even severe acne, in about ⅔ of people who properly take an adequate dosage. However, it permanently and irreversibly changes the skin and the body forever and users may experience long-term side effects for the rest of their lives. It’ll nuke it, but there is no going back.
Oral Retinoid
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Isotretinoin (Accutane®)
Compare To Other Treatments
5
37.1%
4
33.4%
3
15.5%
2
7.3%
1
6.6%

Used Isotretinoin (Accutane®)? Rate It:

Choose from 1 to 5 stars
September 27, 2008

Pros:

It worked!

Cons:

Monthly visits to the doctor. Nothing else that chapstick or moistoriser couldn't control.
I paid $10 a month for the RX plus $20 co-pay each monthly dr. viist, so that got expensive.

I was on Sotret (accutane) from January 5th to Septemer 5th - that's a long time! Basically my acne is caused by stress, and I learned this through taking accutane, because when I wasnt stressed, I got no pimples and accutane was really that "amasing pill" you heard about. When I was stressed, I would break out, even on Accutane. It changed my acne from slow healing to fast healing, and way smaller pimples. Basically, find out what causes your acne. Mine is stress so hopefully I will be able to maintain the results accutane has given me. I would say try it for yourself, start with a low dose (like i did), work up to higher dosages, and just see how your body reacts. I wish I would have gone on it earlier. Oh and I got bad blood tests going each month, such as "high liver function" and "low white blood cell count." I didn't let that scare me because you just adjust to a different dosage that your body agrees with. Try it and stop wondering! I wish I wouldve gone on it ten yrs ago. (24)
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August 27, 2008

Pros:

Good if you have health insurance, Clears up nodular acne, dries out blackheads

Cons:

Not a permanent cure, Gets worse before it gets better

I have always had light acne with blackheads and a rare cyst every now and then, since about 12. At 18 my face exploded in cystic-nodular acne (it's genetic in my case). I, for some strange reason, avoided seeing a derm even though I had health insurance for a year. Because of this I have scarring. As soon as my derm saw me she wrote me a script for Accutane. It definitely got worse before it got better. I loved how all my blackheads practically committed suicide and fell out of my face. I wasn't totally cured, but after treatment I would only get a couple before my period. Still have to use makeup because of scarring, but people actually compliment me on my skin now. I was looking this up because my acne is back (6 years later) and am considering using it again. Hair loss.... Now I'm totally petrified!!!!!!!!!!
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August 15, 2008

Pros:

works really good, its the only thing that got ridof my acne

Cons:

2 yrs later it came back

recommended
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June 10, 2008

Pros:

Clears up acne!

Cons:

Acne can return, dry skin/lips, headaches, blood tests.

Use Accutane if you have tried other things without success
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June 10, 2008

Pros:

Clear, beautiful skin!

Cons:

EVERYTHING is dry-- My eyes, ears, lips, skin, and even down there... also experienced fever and chills one day. You can't wax, get a facial or have anything lasered. Sun sensitivity. Huge pain to have to take a pregnancy test every month.

I'm about a month into my second course of accutane and absolutely recommend it! For me, the side effects are pretty minimal-- I religiously apply aquaphor on my lips and use cetaphil lotion on my face/body. I had a bit of an initial break out, but now my skin is looking great! My skin is almost completely clear, skin tone evening out, scars are getting lighter. I even feel like I look younger... The best part-- I've been getting compliments on what beautiful skin I have by strangers and friends. I think this is probably the best my skin has ever looked! Also, I think my pores are shrinking and there is definitely less oil. Usually by the end of the day the makeup on my t-zone is totally gone; it's 9:30pm and my makeup still looks fresh! Despite the side effects, I AM SO HAPPY THAT I WENT ON ACCUTANE!! Nothing else worked for me... I've tried all the topicals, antibiotics, over the counter, light therapy, facials... like I said, THIS IS THE BEST MY SKIN HAS EVER LOOKED!
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May 18, 2008

Pros:

I took Accutane about 15 years ago for the first time and had no problems whatsoever with it. I have since had a booster dosage about 8 years ago and my skin is great now. I had horrible cystic acne growing up and still have scars on my face from tho

Cons:

None--It worked. I'll take any side effects for a product that rid me of acne.

Accutane is the ONLY cure for cystic acne. All other medications will manage the acne, but as soon as you go off the medicine, the acne comes back.
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April 17, 2008

Pros:

-much clearer skin
-can go long periods with having to wash hair
- no more breakouts

Cons:

-severe dry lips and nose
-nose bleeds
-stiff joints

its def. worth it, its frustrating the first few weeks because of severe nose bleeds and dryness but its good knowing that its taking it away in the longrun. I tried literally everything without it workingat all before so this is amazing. I think its important to not get discouraged with the uncomfortable side effects because you might find out it works perfectly.
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April 14, 2008

Pros:

cleared up severe acne,scars have reduced.

Cons:

sinustis.

everytime i used the isotretinoin gel i have difficulty breathing. this gel caused acute sinusitis. but it was effective against acne.
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February 25, 2008

Pros:

Number of breakouts dramatically reduced, smooth clear skin. After my 4 months on it, prescription creams started to actually work!

Cons:

Dry lips, dry skin and joint pains(in knees which was a killer for soccer)

I had used at least 7 prescription creams up to Accutane and went to 4 different dermatologists. Accutane is amazing, I saw improvements within weeks and cleared up skin(shoulders, chest and face) within a month. I have two friends with really bad severe acne and I recommended it to them and they are both seeing the same improvements. If you have severe acne and have tried many other things, then this is definitely for you, I would highly recommend bringing it up with your dermatologist. It, just works. However, when you take this, there are a number of side effects(they are listed on the iPLEDGE form) but, I was desperate and found it worth the couple side effects to finally see clear acne.
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February 5, 2008

Pros:

None, this was just awful

Cons:

fatigue, depression, incredibly dry skin, nosebleeds, hairloss, backaches

I was prescribed accutane 3 times over the course of 5 years. the first time i took it for 9 months, the second time 9 months and the third time i had to take a modified course of 1 pill every other day for 11 months. It didn't work. My Acne was overwhelming while I was on it and in addition to the horrid cysts, my skin would peel off in strips (now mind you I still had to work!). My acne did not clear up while on it, or after. It made my hair fall out for years and it's never. I was at a business lunch with my boss at the Ivy and my hair was falling out in clumps, alllll over the table. it was humiliating. I eventually had to be prescribed a antidepressent and to this day, 10 years later, I still have to take it. My lips are still cracked and peeling to this day. I have to use a lip balm all day and all night. I was never sensitive to any medication before, I was not resistant to most medications but I do have stubborn acne. Accutane doesn't work for everyone and I'm living proof.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.