Isotretinoin (Accutane®)
Read All About Isotretinoin (Accutane®)
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May 21, 2013

Pros:

Your skin may clear

Cons:

You may lose your life

I would like to address to you who are about to run a course of Accutane. This pill takes lives every year and almost got mine as well. It's a harsh chemical with countless of side effects on body and mind and is to be considered a high risk solution and not to be coursed at all. Looking at it from above its a vitamin A overdose. It does actually help cure acne in some cases, in others ruin peoples lives. I took two courses on doctors prescription orders and as for the physical side effects you can expect dry lips and skin, stiff joints, impaired nightvision, dry mucous membranes (especially nose) that may cause nosebleed, tendencies to tooth loss and headache to mention a few, For the mental side effects however these are much more extensive and can be considered life threatning. While on course you will experience lowered mood. As the course laps this may worsen and develop inte full scale depression if unlucky and may cause insanity if not stopping on time. Post cycle my speech was slurry and everything had slowed down. I used to have countless of ideas flowing inside my head. This was all gone after the last cycle. Other physical side effects post cycle were heavily reduced sex drive, reduced sperm quality and semen colored yellow. This caused panic by itself and a lot of pain on ones mind. The primary function of accutane is to lower your testosterone levels and its this effect that makes your skin clear, reduced sebum levels and so forth. This is of course also what causes mood swings and its not mentioned in the PIL that follows. Also brain injuries as mentioned above, because its a vitamin A overdose it does damage your brain as well. We are looking at permanent loss of brain cells. Before the last cycle I was in one piece This red pill produced by roche should be banned and not to be sold in any state or country. If you think of running a course heed my warning. This is not something you want A few thoughts on accutane
September 30, 2015
Hey bbbmmm222, I think it's rude of you to criticize other's reviews of the drug, by picking on bad grammar and wording, are you wanting to take the drug but scared and offended by the bad reviews? It's well known that this is a dangerous drug. This person has listed out all of their side effects and they are not required to show evidence or dr's opinion on a review lol. I don't see why anyone would want to fear monger here .
September 30, 2015
Hey bbbmmm222, I think it's rude of you to criticize other's reviews of the drug, by picking on bad grammar and wording, are you wanting to take the drug but scared and offended by the bad reviews? It's well known that this is a dangerous drug. This person has listed out all of their side effects and they are not required to show evidence or dr's opinion on a review lol. I don't see why anyone would want to fear monger here .
May 19, 2013

Pros:

Clears up skin perfectly
Stops excessive oil while you are on treatment
Gain extra confidence :)

Cons:

Can't take forever or indefinately
IBS symptoms/ Bowel problems
Mood changes

If you want a honest review from my point of view then read ahead. For quite a few years I suffered with cystic acne. It started off mild with just comedones and blackheads but with time it became more inflammatory, with pustules than eventually cysts that were the size of a marble deep in my cheeks. It carried on for a good few years between me being 17-21 years of age, and as my acne increased my self-esteem & confidence decreased. During this time, I was put on antibiotics, which initially worked but after 6 months I became resistant to them. I was given differin which I used for a few weeks but after not being satisfied with results gave up on it. I then tried benzoyl peroxide which I found too irritative. Skinoren (azelaic acid) was given to me and was quite helpful but again, I was not satisfied with it. In hindsight I can see I did not give any topical a good chance. I was so convinced my acne was resistant and actually believed I would suffer with cysts forever. When I was about 20 my family advised me to cut out junk foods (especially foods high in sugar and trans-fats) and dairy as these were rumored to encourage acne. I cut out bread, gluten, sugar and even tea and coffee and kept waiting for instant results. I even drank 8 glasses of water religiously and took up exercise. Of course, with my severe acne instant results were not possible and with my confidence being eroded with every new cyst I became quite depressed about it. It was around this time I decided to go back to the doctors. I was very embarrased about my skin condition. I was excessively oily and flaky at the same time, with cysts all over my cheeks, nose and forehead. I was at the point where I was even embarrased to make eye contat with people because I thought they would think my skin was gross. Heck , even a stranger once told me to get medication for my skin. Anyway, I told my GP everything and was in tears by the end, so he immediately reffered me to a dermatologist to be put on Isotretinoin. I was counselled that there would be side effects, but since my acne was severe and it was affecting me psychologically, that it would be a sensible and good option for me. In the UK women of childbaring age are recommended to take birth control whilst on this medication, as it toxic and can affect the development of foetuses. I was not sexually active at the time and decided not to take the Dianette contraceptive they were giving me. The dermatologist was not happy about this, but I signed a form which basically said I can take responsibility for my own vagina lol. Fast forward some time and I had just completed my first 5 months. I was on a very low dose (about 10mg a day) and my weight was about 50kg, so it worked very slowly for me. I remember being quite down at this time because even though I had seen some improvements my face was still red and breaking out occasionally. I still wanted the clear skin instantly and craved for the results I'd read about on here. In hindsight, I can see it was actually working, but as I was constantly observing my skin daily I couldn't actually see a big difference. The thing with retinoids are they DO work, but any differences are very subtle. It took a good few months for me to be satisfied with results. After a good 8-9 months on 10mg, I rememeber looking into the mirror and realising how far my skin had come. It was around this time the spots had stopped, redness from previous marks had finally faded and my skin actually glowed. It looked so fresh and I was delighted. I atually felt like a con at times as people started complimenting my skin and asking what creams and cosmetics I use. I found this so funny as I knew it's all down to the Isotretinoin. After I completed the course the clear skin continued for a few months. After this I started getting quite oily again and breaking out with smaller spots. The comedones were back again, although a lot milder than what I had before. I was disappointed but went to the doctors and decided to use a topical retinoid and so far it has cleared my skin again. Bottom line is retinoids do work, inside or out, but you have to give them time. I have looked into the symptoms of acne and especially after treatment with Isotretinoin, I realised as long as I keep the skin cells from being blocked by an over production of keratin, keep my sebum controlled (which my isotrex topical retinoid does) and make sure the bacteria is not out of hand, then my skin can remain clear. If only I knew this before! Overall, to get to my cumulative dose it took about a year and a half. I did experience side effects. Obviously the very dry and sensitive skin made my red marks and spots look a lot worse when beginning treatment, but as my skin improved and I adjusted to the sensitivity, it stopped being such a problem. To this day I still use a simple moisturiser without fragrance, don't over exfoliate with harsh scrubs and generally just leave my skin alone. This all helps with dealing with the extra sensitivity and you will soon find you and your skin can adapt to it. I also had bowel problems wit this. It seemed to upset my stomach, particularly in the last few months. I had excessive gas and diarreah. It happened even though I always took the capsules with food. It reduced significantly when I finished my course, but I still have an upset tummy at times. However, I don't regret taking this drug as it cleared my skin immensley. I got great results from it and most importantly, I have my confidence back. To those who are struggling with acne and it is affecting you psychologically, you really should not be afraid of the side effects. The damage to your confidence and self esteem can have long term effects in itself as it will inevitabley start affecting you everyday life, and acne is so not worth that damage. I will never regret taking Isotretinoin as it was the start of helping me get my confidence back. Having my confidence is helping me in my life to get a new job, have a career and even finding love. So if you have acne, don't feel it is something to hold you back as I did for many years. I am nearly 24 now and very happy :)
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May 15, 2013

Pros:

clearn skin fast
easy to take
miracle pill

Cons:

dry lips
dry eyes
must fill out the ipledge program questions

Miracle pill. I had really bad acne when I went to visit the dermatologist. She prescribed accutane, it cleared my skin so fast. My pimples were leaing dents but this cleared my pimples within 3 month
May 13, 2013

Pros:

can clear up acne

Cons:

dry lips and eyes
can cause depression
time consuming

I had HORRIBLE acne that was causing me to be embarrassed and very depressed. I tried several medicines and finally i was put on accutane, twice. It really did clear up my acne but it came with a price. since taking it My eyes are now dry all the time, joint pain, depression, etc. I would recommend this only as a VERY LAST RESORT. this is not something to play around with and I wont take it again because there is too much risk with this medicine. AND for a girl it is hard because of all the Birth control and pregnancy tests.
May 4, 2013

Pros:

Clears your acne

Cons:

Can be expensive
Quite a lot of side effects
Can have side effects years after

I had very bad acne when I was 21, I'm now 37. Endless amount of tablets and creams, my doctor finally sent me to hospital and I was given Accutane (think it was called Roaccutane back then) for 3 months (I think). It totally got rid of my acne. But when I was taking it, I lost sleep, had nose bleeds, lost my appetite and felt drowsy. Even if your acne isn't bad, I don't see the point in using anything else other than Accutane. I should have been put on Accutane earlier, but due to that not being the case, it caused scarring. But it wasn't until I got into my late 20s, I noticed that my skin started to change. It would become red and it would show up my scarring. Doing some research, it appears that you can have side effects years later. It's also been found that drinking high amounts of milk can cause acne and make your acne worse. This was found in a recent study in England.
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May 3, 2013

Pros:

Skin is MUCH less oily
Very few breakouts (1/month)
Haven't had this much self-confidence for a long time

Cons:

Extremely sensitive skin (while on the drug)
Pain in joints when doing explosive work (i.e. not warming up before sports)
VERY dry lips

So, I'm a male, 17 years of age, weigh about 67 kg and am about 1.80m. Since the age of about 15, I started getting acne. At the start it was never too severe, a few white heads every week, but blackheads all over. I went from dermatologist to dermatologist, trying over 20 products and spending an insanely large amount of money. Nothing worked. Finally, I got to a dermatologist who said they would put me on accutane, my course dosage was: Month 1: 20mg Month 2: 40mg Month 3: 60mg Month 4: 60mg Month 5: 60mg Month 6: 60mg During the course, my outbreaks were hideous. I had huge cysts all over my face, a new white head on a daily basis, and the black heads remained. Now, 4 months off the course, I get a white head every month or so, and no more cysts (thank god & accutane!). The side effects (shown below) were definitely annoying, but they're a price to pay for such perfect results.
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April 22, 2013

Pros:

Cured a lifetime of acne
Improved my confidence
Changed my life for the better

Cons:

Dry skin
Ongoing sensitive skin

I'd struggled my entire life with acne and nothing had ever fully cleared me up. The best I'd found was The Regimen, which kept me fairly clear but not completely and being 25 I knew I was heading towards adult acne. I had to go to a private Dr in London who prescribed Accutane. It felt like one of the best days of my life. I was ecstatic. It cleared my skin and it's been clear since. It was the best decision I ever made. The side effects are nothing compared to a life time of acne.
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April 16, 2013

Cons:

long term issues, older looking skin

The 7 pills that ruined my life. Truthfully, before I thought about taking this drug, I would read the reviews thinking that the people that said negative things about it where exaggerating. I started taking Claravis over a year ago and took it for only 7 days and I regret it every day. It did nothing for my acne at all but has made me feel like a 50 year old. I am in my mid 30's in within a month after taking the drug I have 2 ruptured discs in my back as well as arthritis now. Also, maybe because am older, but the skin around my eyes is parched and is full of wrinkles and the skin on my neck is always dry now. Of course, it would be uneducated of me to say that I am certain that the drug did this to me, but before taking it I was very athletic and an avid figure skater training to go into the sheriffs academy and now I am lucky if I can skate two times a week and sit ups are out of the question with my bad back. I have back pain daily now and I feel like I look more aged, all from taking those 7 pills. The truly crappy thing is that my skin is now flawless after finding the right topical and over the counter med after ten years of searching. I wish I would have just experimented more with other things before taking those pills and perhaps I would be my old self. Now I use Aczone and Alpha Hydrox 14% Intensive serum and I have never been happier with my skin. Maybe it's because I am older that this happened or it could be that it was bound to happen anyway and had nothing to do with isotretinoin. Who knows? My suggestion is to exhaust every avenue before you try this.
April 13, 2013

Pros:

oil free, acne free skin

Cons:

delusions
impaired cognition
colitis
dry skin
schizophrenia

Try Lazer Treatment for Acne before you resort to this.. Ok so yes the effects of it were amazing although not permanent, I decided to not not through the full treatment, because it was literally making me stupid, and often throughout day I'd suddenly not know why I was where I was, my friend's mother took it and got ulcerative colitis for life, and schizophrenia, and I wouldn't be able to think straight, my grades dropped by 2 letter grades, so try everything else out first, you don't want to become acne free but get stuck with colitis for life...
April 5, 2013

Pros:

It WORKSSSS!! Happiness. Results.

Cons:

Chap chap lips. Dry skin. Intial breakout.

Before I went on accutain I had tried EVERYTHING... constant Cremes, Benzyol Proxide, 3 different antibiotics, retin A Creme... you name it I used it. None of these things really worked for me; it would only suppress my acne. BTW.. I should inform everyone on here that I never had awful acne, I had moderately severe acne that I was sick of dealing with. I finally decided to go on accutain and I will admit I was really scared. Thr first two months were rough not going to lie; after those two months my face started looking better and better. Now I have NO acne on my face just a couple on my back... it really is AMAZING. Don't let anyone stop you from taking this medication... it works and no one should suffer with acne!!! I have one more month so lets hope I get 100% clear!! I'm at about 88%.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.