Oral Retinoid
Reviews
3.9
2791 Reviews
Oral Retinoid
Efficacy
87%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Use with EXTREME CAUTION: Causes severe birth defects and fetal death.
Oral Retinoid
Side Effects
High
Oral Retinoid
Acne.org’s Real World Take
The nuclear option. It works reliably and provides long-term remission of acne, and even severe acne, in about ⅔ of people who properly take an adequate dosage. However, it permanently and irreversibly changes the skin and the body forever and users may experience long-term side effects for the rest of their lives. It’ll nuke it, but there is no going back.
Oral Retinoid
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Isotretinoin (Accutane®)
Compare To Other Treatments
5
37.1%
4
33.4%
3
15.5%
2
7.3%
1
6.6%

Used Isotretinoin (Accutane®)? Rate It:

Choose from 1 to 5 stars
May 21, 2013

Pros:

Your skin may clear

Cons:

You may lose your life

I would like to address to you who are about to run a course of Accutane. This pill takes lives every year and almost got mine as well. It's a harsh chemical with countless of side effects on body and mind and is to be considered a high risk solution and not to be coursed at all. Looking at it from above its a vitamin A overdose. It does actually help cure acne in some cases, in others ruin peoples lives. I took two courses on doctors prescription orders and as for the physical side effects you can expect dry lips and skin, stiff joints, impaired nightvision, dry mucous membranes (especially nose) that may cause nosebleed, tendencies to tooth loss and headache to mention a few, For the mental side effects however these are much more extensive and can be considered life threatning. While on course you will experience lowered mood. As the course laps this may worsen and develop inte full scale depression if unlucky and may cause insanity if not stopping on time. Post cycle my speech was slurry and everything had slowed down. I used to have countless of ideas flowing inside my head. This was all gone after the last cycle. Other physical side effects post cycle were heavily reduced sex drive, reduced sperm quality and semen colored yellow. This caused panic by itself and a lot of pain on ones mind. The primary function of accutane is to lower your testosterone levels and its this effect that makes your skin clear, reduced sebum levels and so forth. This is of course also what causes mood swings and its not mentioned in the PIL that follows. Also brain injuries as mentioned above, because its a vitamin A overdose it does damage your brain as well. We are looking at permanent loss of brain cells. Before the last cycle I was in one piece This red pill produced by roche should be banned and not to be sold in any state or country. If you think of running a course heed my warning. This is not something you want A few thoughts on accutane
September 30, 2015
Hey bbbmmm222, I think it's rude of you to criticize other's reviews of the drug, by picking on bad grammar and wording, are you wanting to take the drug but scared and offended by the bad reviews? It's well known that this is a dangerous drug. This person has listed out all of their side effects and they are not required to show evidence or dr's opinion on a review lol. I don't see why anyone would want to fear monger here .
September 30, 2015
Hey bbbmmm222, I think it's rude of you to criticize other's reviews of the drug, by picking on bad grammar and wording, are you wanting to take the drug but scared and offended by the bad reviews? It's well known that this is a dangerous drug. This person has listed out all of their side effects and they are not required to show evidence or dr's opinion on a review lol. I don't see why anyone would want to fear monger here .
December 7, 2012

Pros:

Clear acne while on it.

Cons:

HORRIBLE breakout after

Listen guys, I was on this product for a total of 19 days. I took a pill in the morning and a pill at night. My acne was normal at the time, ya know some bacne chestne, and around cheeks. Now let me tell you if you have sensitive eyes, this product is NOT FOR YOU. I have very oily skin and dark hair but blue sensitive eyes. I could barely open my eyes and bright light sensations were imminent. While driving at night I could barely see anything. EXTREME eye irritation so i had to get off. Always watery eyes and red and irritated. Now my acne was almost CLEAR at that point. This is truly a double sided sword. I few weeks after my acne started to get progressively worse. I got the WORST foreheadne in my life, and I never got any foreheadne! My breakouts went crazy everywhere for months!!! My eyes still werent healed! It's a year later and after trying numerous products and herbs it has finally calmed down a bit. My eyes are still not 100%. And I still get lots of foreheadne which I never got. I can see this product working for someone staying on the full dose but with all the sideeffects it is worth it to find an alternative. PLEASE THINK TWICE BEFORE GETTING ON THIS, my life was so much better before I got on this product.
September 24, 2012
I used this 3 years ago. all it did was make me sick, give me cracked lips-severe! and my acne all came back as soon as I stopped. My regular doc wouldn't even prescribe this i had to go see another doc, now i know i should have trusted my own doc! I used zenmed 2 years ago and my skin totally cleared up and stayed cleared up and it didn't do nasty things to my body either. unless u really don't care about your body STAY AWAY from this stuff.
February 29, 2012

Pros:

Clear skin

Cons:

Photosensitivity terribly
Constant dry skin
Eczema rashes occur at times

I would not recommend this at all. The distress and negative it has caused definatly outweighs the no acne situation. I am currently on holiday with my fiancé FOUR MONTHS post tane. And it has been a nightmare. I cannot expose my skin at all in the sun as I made the mistake of doing so and I am now severely sunburnt with blisters etc even though I used factor 50 SPF. I know for a fact it is because of the tane as i had very good skin in the sun before accutane. I cannot stress enough the negatives that can come from this medicine I regret taking it. Please read all of the negative comments about accutane before thinking it is a miracle drug. There are real people out there who have a lot worse outcome than myself which could happen to you.
May 20, 2008

Pros:

you will think it works, but....

Cons:

VERY DANGEROUS! CAUSES BACTERIA DISBALANCE IN YOUR DIGESTION, YOU RUN HIGH RISK OF HAVING CANDIDOSIS AFTER USING IT!!! CANDIDOSIS CAUSES ACNE!!! STOP AS SOON AS YOU CAN! ACNE WILL COME BACK

it is absolutely clear that this medication is highly dangerous and has not cured anyone in long term! You will end up treating your candida for the rest of your life! Please read: Accutane - Dangerous Answer For Severe Acne ([link removed]>Accutane and alike, provoke an overgrowth of fungus called candida- WHICH CAUSES ACNE!!! Yeast infection is almost impossible to treat! you will be on a strict diet for the rest of your life or will end up not knowing what has actually happened to you, blaming it on different external treatments. Please investigate before using it! be more careful! doctors who write prescriptions for it make huge mistake and they know it!
December 16, 2011

Pros:

Nothing

Cons:

messed my eyes up
messed my stomach up
dry skin
still bad acne

Don't take this it better to have acne then have bad health now i need to take medicine for my stomach and I still have pain sometimes. I still don't know what wrong with my eyes. Plez don't take this for the sake of your health! My problems are not big but still don't take this it better to have no problems!
November 7, 2009

Pros:

So far I haven't seen any improvement in the appearance of my spots but they are less sore.

Cons:

Blood test every month. And I've experienced so many side-effects. Cracked lips. Dry peeling skin. Red itchy flaky patches on my arms. Red bumps on the back of my hands. All the dryness is making my skin feel like it got burned.

I haven't had any improvement in my acne probably because I haven't been on the medication long enough. I'm going to continue to take it for 6 months as advised by my dermatologist and hopefully it works.
March 23, 2013

Pros:

so far its been 11 days on accutune. Pros, it really does dry up your skin! iv read so many reviews about it working in the long term so i hope it does. My skin isn't as oily as it use to be. The size of the pimples have decreased and i only get small ones now.

Cons:

It makes you really moody and im still breaking out a bit. And really dry and flaky lips and flaky skin! So hard to wear makeup with! And iv never been so depressed in my life!

Have to wait a little longer to see results as its only been 11 days. My skin hasn't really changed much except i have been breaking out a bit. Im dying to know how long til i see results and i really dont want to go through a major breakout likes your meant to. Ahhh.
January 9, 2013

Pros:

None.

Cons:

Vastly Increased Acne
Dry/Peeling Skin
Dry/Peeling Lips
Inflamed/Red Face
Itchy Skin
Scaly Skin
Depression
Headaches
Hives
Dizzy Spells

I do not recommend this at all. I thought it had to work because it was one of the only things I hadn't tried, but obviously not. I had to stop using it within weeks because it caused mental and physical pain.
August 9, 2012

Pros:

None!

Cons:

SIDE EFFECTS!
ACNE MAY RETURN!
NOT WORTH THE RISK!

It has terrible side effects! If your thinking about using this product please don't! The side effects are not worth the prize. So what if you cleared your acne but screwed up a bunch of other things in your body. Please read the side effects of this product and know that there is a good chance that they may happen to you!

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.