Oral Retinoid
Reviews
3.9
2791 Reviews
Oral Retinoid
Efficacy
87%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Use with EXTREME CAUTION: Causes severe birth defects and fetal death.
Oral Retinoid
Side Effects
High
Oral Retinoid
Acne.org’s Real World Take
The nuclear option. It works reliably and provides long-term remission of acne, and even severe acne, in about ⅔ of people who properly take an adequate dosage. However, it permanently and irreversibly changes the skin and the body forever and users may experience long-term side effects for the rest of their lives. It’ll nuke it, but there is no going back.
Oral Retinoid
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Isotretinoin (Accutane®)
Compare To Other Treatments
5
37.1%
4
33.4%
3
15.5%
2
7.3%
1
6.6%

Used Isotretinoin (Accutane®)? Rate It:

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April 3, 2008

Pros:

i've been on this for a month and it's cleared up my forhead very well and my back has cleared up dramatically already but not my trouble spots around my mouth

Cons:

It has gotten a little worse so far. Dry Skin...dry, cracked lips but not too bad

i have a great feeling about this medicine after being on everything else, and i mean EVERTHING...proactiv, oxy, duac, benzaclin, ziana, soloyn, phisoderm,u name it i was on it....i just went on this about a month ago and everythings clearing up pretty well except around my mouth which is where its pretty bad....forheads great and my back looks awesome already. I'm goin to th derm tommorrow and hopefully hell bump me up from 40mg's to 80mg's
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April 2, 2008

Pros:

DEFINATELY clears skin up. Got a nice lip-moisterizing prescription from my doctor that i still use :-]

Cons:

started taking it over 3 years ago, havent taken it for about a year due to the fact that i got TERRIBLE mood swings, i had crying spells, my skin dried out real bad for the first couple months, and i got nauseated sometimes after taking it

I had real bad side effects, majority of the ones that they warn you about. -but- It's worked perfectly for a girl i know. it's different for everyone i guess
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March 25, 2008

Pros:

I've only been on this for about a month and my acne did about a 270. Almost there! =)

Cons:

chapped lips and dry skin

use this stuff. it works. most of the time all of the side effects that you read about aren't the side effects that you'll get. most of all it's chapped lips and dry skin.
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March 24, 2008

Pros:

Skin is left soft and smooth, redness has gone down considerably.

Cons:

None so far, I haven't experienced the dry lips, depression, or fatigue. The only con is the monthly blood tests but that is minor.

Before being on Accutane I tried everything from various antibiotics and creams nothing worked! I have been on Accutane for only a week now and my skin is soft and smooth, the bumps have gone away and the redness has gone down. I must admit before getting Accutane I was hesitant to start taking it but honestly I don't really feel much different at all. I would highly recommend to those that have tried everything and have gotten no results.
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March 3, 2008

Pros:

less oil, no blackheads

Cons:

really bad IB, dry skin, weird rashes, moods

Im 15 and its been just over 3 months and i still can't see proper improvement. Am i just kidding myself that its still going to work or is there still hope? My IB was horrible, most spots have gone but they have all left marks that look as bad as the actual spots. Please can someone reply to this and tell me if it could still get better. Im only young and i dont want to be stuck wearing makeup every day for the rest of my life.
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January 31, 2008

Pros:

dry skin, dont need to wash ur hair as much, confidence, happiness. IT is amazing

Cons:

nothing so far

Been on it for 3 months so far. Only have 1 zit on my face. I now get a zit once every 2-3 rather than 2 zits a day. I don't know if this is forever...but even if i have nice skin for 6 months i am happy. I havent had nice skin in about 7 years. no side effects
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January 10, 2008

Pros:

dried up my oil glans. didn't have to was my hair as often. did clear it up somewhat.

Cons:

SIDE EFFECTS. night vision is bad, always tired, not as hungry (lost weight), very touchy (little things made me mad), scaring of breakouts i got while on it and any cut i got, bloody noses, depresstion, joint pain,

skin looked better while on it, but i still had probems. after the first time on it went back to how it had been before. and i went on it again. side effects the 2nd time were worse than the first. but i have heard it work wonders for people, but it doesn't work for everyone. but it is worth trying
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January 7, 2008

Pros:

clear, non-oily skin when NOTHING ELSE worked

Cons:

took about 4 months to work, dry skin during treatment, extremely chapped lips, frequent nosebleeds, aching joints

here is my brief story: I started off with mild acne and used products like benzaclin and duac, 2.5% benzoil peroxide creams, to help. Those didn't work, and when my acne became "moderate", I was put on doxycycline. After four months of doxycycline and retin-a alternating with benzoil peroxide, my acne worsened. I tried natural treatments, basically every acne product on the market. It wouldn't go away. After much contemplation, I was put on accutane. Fast forward four months-- perfect skin. People telling me that they want my skin. What a turnaround! I do have some minor scarring but it's not much at all, and it is very easy to cover up. I went from severe acne with no hope to perfect skin. If you've tried what I had tried and it didn't work, go on accutane immediately. You deserve it.
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December 20, 2007

Pros:

I've been on sotret for about 2 months and my acne got worse at first. Now it seems to be getting better and I hope it continues.

Cons:

Dry lips and skin but that's it. For clear skin it is completely worth it.

It's worth a try.
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December 11, 2007

Pros:

It cleared my face temporarily. I took it for 6 months then was off for two years, then took it for six months again and I still have acne.

Cons:

A lot of office visits, blood drawns, follow up appoinments. Seemed like my life revolved around derm appointments.

It is the only thing that has ever worke but it is onlu temporary. It will come back with a vengance. My face looks horrible and I am in my thirties. I have battled this for 15 years and still am. Nothing helps. I have spend thousands of dollars on everything on tv, over the counter, and presciption medications. Nothing works.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.