Excision with Intralesional Corticosteroids

Compare To Other Treatments

What Is It?

First, a raised scar is surgically removed. Then, to prevent the recurrence of the scar, excision can be combined with the injection of corticosteroids, usually, corticosteroid called triamcinolone.


Even though excision combined with intralesional corticosteroid treatment completely removes the scar(s), in some cases, scar(s) may grow back after the treatment.

Non-recurrence rate

Strength of Evidence
1
2
3
4
5
Permanently reduces the scarring in 84% of cases
▸ Based on These Clinical Studies & Trials
▾ Based on These Clinical Studies & Trials
  1. Jiang, Y. et al. Surgical excision and skin grafting combined with intralesional injection of triamcinolone for the treatment of keloids after syndactyly release. J Hand Surg Eur Vol 48, 346–352 (2023).
  2. Wang, Y.-Y., Wang, K., Chen, W.-L. & Wang, Y.-M. Use of Retroauricular Flaps to Reconstruct Defects of the Helical Rim and Adjuvant Intralesional Corticosteroids after Resection of Large Keloids. J Craniofac Surg (2022) doi:10.1097/SCS.0000000000008633.
  3. Yıldız, E. Triple treatment in ear keloids: comparison of post-excisional intralesional steroid and platelet-rich plasma treatment. Am J Otolaryngol 42, 102935 (2021).
  4. Burusapat, C., Wanichjaroen, N., Wongprakob, N. & Sapruangthong, R. The effectiveness of immediate triamcinolone acetonide injection after auricular keloid surgery: a prospective randomized controlled trial. Plast Reconstr Surg Glob Open 9, e3729 (2021).
  5. Aljodah, M.-A., Alfeehan, M. & Al-Zajrawee, M. Outcome of recurrent auricular keloid treatment with a combination of surgical excision and perioperative corticosteroid injection. J Cutan Aesthet Surg 14, 392 (2021).
  6. Choi, Y.-J., Lee, Y. H., Lee, H. J., Lee, G.-Y. & Kim, W.-S. Auricular keloid management in Asian skin: clinical outcome of intralesional excision and postoperative triamcinolone acetonide intralesional injection. J Cosmet Dermatol 19, 3041–3047 (2020).
  7. Bijlard, E. et al. Intralesional cryotherapy versus excision with corticosteroid injections or brachytherapy for keloid treatment: randomised controlled trials. J Plast Reconstr Aesthet Surg 71, 847–856 (2018).
  8. Danielsen, P. L. et al. Verapamil is less effective than triamcinolone for prevention of keloid scar recurrence after excision in a randomized controlled trial. Acta Derm Venereol 96, 774–778 (2016).
  9. Bashir, M. M., Ahmad, H., Yousaf, N. & Khan, F. A. Comparison of single intra operative versus an intra operative and two post operative injections of the triamcinolone after wedge excision of keloids of helix. J Pak Med Assoc 65, 737–741 (2015).
  10. Al Aradi, I. K., Alawadhi, S. A., Alkhawaja, F. A. & Alaradi, I. Earlobe keloids: a pilot study of the efficacy of keloidectomy with core fillet flap and adjuvant intralesional corticosteroids. Dermatol Surg 39, 1514–1519 (2013).
  11. Hamrick, M., Boswell, W. & Carney, D. Successful treatment of earlobe keloids in the pediatric population. J Pediatr Surg 44, 286–288 (2009).
  12. Sclafani, A. P., Gordon, L., Chadha, M. & Romo, T. Prevention of earlobe keloid recurrence with postoperative corticosteroid injections versus radiation therapy: a randomized, prospective study and review of the literature. Dermatol Surg 22, 569–574 (1996).

Side Effects

High
High side effects and adverse reactions

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