What Is It?
Clascoterone, sold under the brand name Winlevi®, is a topical cream that works by blocking the effects of male hormones that in the skin contribute to acne development. It’s the first topical treatment of its kind to be FDA-approved for acne and offers a new mechanism of action compared to other acne treatments.
It is usually applied twice daily, in the morning and in the evening.
Results
Results
Strength of Evidence: Strong
Average 46% reduction in acne after 12 weeks
Side Effects
Side Effects
Low side effects and adverse reactions
Acne.org's Real World Take
It’s different from anything else because it targets male hormones in the skin, but it doesn’t seem to work all that well compared to other options. Plus, it’s good to have an eye out for new medications until they have been proven safe over many years. You can’t deny that it’s interesting though, and it might prove to be a nice tool alongside other meds.