Isotrexin : Erythromycin (2%) and Tretinoin (.05%) Gel

Brand:
Reviews
3.7
115 Reviews
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Active ingredients:
Erythromycin (2%) and Isotretinoin (0.05%).

Inactive Ingredients:
Hydroxypropylcellulose, butylated hydroxytoluene and ethanol.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

5
27%
4
38.3%
3
18.3%
2
14.8%
1
1.7%

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April 3, 2008

Pros:

Brings spots out and you begin to see your skin begin to gradually get better.

Cons:

As with most topical treatments, does take a while to star working. While ive been using it ive had several breakouts and im not sure if its a good thing?.

use it because it does work. and also persist with it cos im sure it will definetley have some effect. ive been using it 5 weeks and its certainly cleared lots of spots up but has just made them more inflammed. fewer spots but does look worse from the outside. surely after time (say for me another month?) they should go... :D
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November 23, 2009
I'm using it for a week and three days. Too early to come to a conclusion, since my dermatologist told me I won't see any results before 6 weeks. My case is maybe a little different. I've no acne all over my face. I have a single cyst on my right cheek. This thing appeared out of the blue and has been there for almost two months really messing with my nerves. The doctor told me it was a acne cyst. Ok, so far, a week after initializing the treatment, the area is reddish and started to peel. I'll be persistent and I'll use this at least for 3 months. Lets hope it works!! I'll be back to share my experience. Until that, good luck to you all.
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November 12, 2008

Pros:

Skin less oily
Clears stubborn blackheads
Wears down old troublesome spots

Cons:

Can only be used at night due to peeling effect
Exfoliating in morning to clear dead skin

Great product but you need to be dedicated to completely cleaning your skin in the morning otherwise the skin it has peeled away will just clog your pores even more. I was prescribed it in combination with an anti-biotic so improvements in my skin may not have been totally up to the gel!
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March 23, 2008

Pros:

Helps unclog closed comedones, works best in co operation with anti biotics
Can also potentially help reduce shallow scarring with prolonged use
Free from my dermatologist (UK- NHS)

Cons:

Initial breakout may be experienced

Can leave skin very dry - try to avoid using in the bits where the tip of your nose meets the upper lip/cheek as it is very irritating

Reccomended with use of antibiotics which shange every few months as the bacteria become resistant to it, this combination worked ok for me but accutane is the real answer for acne if this dosent work
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July 29, 2016
Best retinoid for me
Out of all the topical retinoids offered to me through my 12 years with acne this has been the most effective. My acne is extremely resistant to treatment and I've been on Accutane twice but this kept it at manageable levels. If starting out with this, only use it a few nights a week. It's drying and irritating. Each time I've gone back to using it I've had an extreme initial breakout / purge which is so difficult to deal with but overall it's my favourite topical I go back to again and again.
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AR1995
September 6, 2016
Hi, I am 21 male. My doctor prescribed me Isotrexin. I have been using it for two months now. Can you tell me how long does it take before the medication actually starts working? Furthermore, how good is this medicine when it comes to dealing with scars. Thank you.
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Ann&toby
October 29, 2017
Please advise where to buy isotrexin gel?
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September 5, 2009

Pros:

Works pretty quickly - only a few days and my spots are already flat and smooth.

Cons:

Very drying and quite harsh to the skin - have to rub alot of vaseline to eliviate the peeling and drying effects.

I would really recommend it - working quickly and i already feel much better - prevents pimples from forming and smooths out all the skin on your face. Probably better for moderate acne, maximum though.
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May 17, 2009

Pros:

Brighter, smoother looking skin with less black heads and spots

Cons:

irritating sting when applied, dry peeling skin

I was prescribed the isotrexin gel along with the oxytetracycline 250mg tablets, i have had to apply it one a day for almost three months now, initially starting with a very small amount on my face and gradually increasing the dosage. It seemed to work straight away (well within a week) with the skin appearing clearer and as other say more 'radiant'. It does however have its downsides, most significantly for me is the way it seems to dry the skin, causing unsightly flakiness if i don't apply sufficient quantities of moisturiser. All in all its an effective easy to use treatment.
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December 11, 2007

Pros:

really does help, reduces the number of new spots forming

Cons:

dry skin, can sting abit when you put it on, peeling

really good, the pro's far out way the cons, it has helped me
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March 3, 2007

Pros:

my dermatologist recommended me isotrexin 2 yrs ago...and it really did help, i used it for 3 months and both the scarring and pimples reduced significuntaly....

Cons:

i stopped for 2 yrs and now have been using it for a month and it does help..the problem is i find it a very unconfortable gel to put on your skin...so iam stopping again now in a few days time & have decided to try the pill & see if that works btter

good luck , and be patient cause this gel does work...but u have to be CONSISTENT on using it every night and leave it on minimun 9 hrs..*********
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January 18, 2008

Pros:

drys your skin so it isnt oily through out the day which looks and feels good also prevents new spots

Cons:

stings like mad when you first put on..don't put to much on this makes your skin peel and iritate also which i did with BP

only bin on it for 2 days but skin isnt irritated (once a day at night) i reccomend. it is similar to the bp
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