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I reckon you could get away with using a very small amount as spot treatment. Just make sure to moisturize extra. Though I'm probably not the most qualified to say this since I've never taken accutane.
I do recommend Avene Tri-acneal. It has glycolic acid/retinaldehyde and is not drying! This during the day and BP at night.
Oh another thing you can do is use a warm compress. Justmicrowave a small damp washcloth inside an open sandwich bag for about 10 seconds (maybe a bit more depends). Then just seal it to trap the heat and use a thin pillowcase to wrap it and gently hold it against the pimple. Do this just before any spot treatment.