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Hey. I literally just asked the same question in another thread. The general advice was to only use Epiduo once a day cause it contains other active ingredients not just Bp, and that can be alittle harmful to your skin if applied more often. So just apply once a day at night. and dont do to much, ive been using this stuff for about a week now and am already seeing an improvement.
Also make sure you use a gentle cleanser before you put on the Epidue cause the first few weeks it can be alittle drying and you dont want a stripping cleanser adding to that. Basically just follow the instructions for how to wash and moisturizer that are given in the Regimen and your skin will thank you.