Jump to content
Acne.org
Search In
Find results that contain...
Find results in...
zhangcha

Which Dosage Is More Effective?

Which one is more effective?

1. 4 months on Accutane. 80mg/day. Total dose 9600mg.

or

2. 8 months on Accutane. 40mg/day. Total dose 9600mg.

Share this post


Link to post
Share on other sites

In theory, in terms of acne clearance, there should be no difference whatsoever.

However, the longer less-intensive treatment is a safer option if the issue of side-effects is a worry to you. I'm not a doctor (unsurprisingly) but there is no objectively 'better' option of the two. Which one you do would depend on a variety of factors such as your weight, acne severity and personal willingness to endure the worst of the 'likely' side-effects (i.e. intense dryness, aches, facial redness etc).

Share this post


Link to post
Share on other sites

The cumulative dosage is really what matters when you are taking accutane. So in theory either of those treatments should be just as effective. Personally I would go for the 8 month course because after experience I was on 40 mg for 2 months and 60 mg for another 5 months and I didn't get clear until month 5. I would be worried if I was on a 4 month course that I wouldn't have enough time on the medication to get clear. After you go through the initial breakout and wait for your skin to stop purging you are usually into your 3rd month. That seems to be the norm with the accutane logs on here and with people I know who have taken the medication. So 4 months I would think just is not long enough of a course. Also according to my dermatologist you are supposed to stay on the medication until you don't experience a pimple in a month period and then she adds another month on top of that.

Share this post


Link to post
Share on other sites

In the long-term, no difference between those options (in theory)


In the short-term, the higher dose may clear acne more quickly (but there will be more side effects)

How much do you weight in kg and what is your acne severity/location?

Edited by biggs881

Share this post


Link to post
Share on other sites

How much do you weight in kg and what is your acne severity/location?

I weight 90kg. The acne on my back was severe. The acne on my face was mild/moderate but scarred easily. I'm on my 5th month of Accutane. I still get pimples on my face but not on my back which is rather odd. The dosage is 60mg per day atm.

Share this post


Link to post
Share on other sites

You are currently taking 0.66mg/kg/day (60mg/day).

Although sometimes derms go higher, the typical daily dose is 0.5-1.0mg/kg/day, which for you is 45-90mg/day.

Since you aren't clear yet despite being in your 5th month, you could ask your Derm to increase the dose to 1.0mg/kg/day (90mg/day) for the remainder of your course, assuming the side effects are tolerable.

Also, since the ideal cumulative dose is 120-150mg/kg to minimise the chance of relapse post-Accutane, you need to take 10,800mg-13,500mg of Accutane in total to maximise the chance of permanent remission.

Good luck

Edited by biggs881

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.


  • Personalized Advice Quiz - All of Acne.org in just a few minutes


×