I replied on another thread too. I am on 50mg a day and started about a week and half ago and I have already loss 5 lbs. I have zero appetite and have to force myself to eat. I am definitely not complaining, but am actually shocked because it seems a lot of people have gained weight while taking spiro. I agree with uphill battle that everybody has a different reaction to the medications they take.
I am taking milk thistle to support my liver, which processes all medications you take, and the side effects are subsiding. I get breast tenderness and cramps from spiro. I did gain 5 pounds initially but that went away.
I take 2 capsules Jarrows Milk Thistle daily
I always take spiro with food
I drink tons of water
I take my second dose before 3 pm because androgens are highest earlier in the day
Those things have reduced the side effects a lot for me.
6 weeks on and lost about 4 lbs. The crazy thing is I am so hungry all the time, and I eat far more than before, but still lose weight. I am skinny anyway so I was never worried if I gain a few lbs, but on me it has a different effect. I eat estimated 2500 kcal a day and haven't worked out for weeks. That is crazy.