On 11/6/2017 at 11:31 AM, LikelyTempo said:

Hi all,
ive been on spiro 100 mg for about 2 years. Recently my derm suggesting adding 25 mg to total 125 mg per day. 

Ive been on this added dosage for about 4 weeks and I've noted more oil! My face and hair seem oiler and I just generally feel icky. My period was thrown off a bit, with a mid cycle period, but I'm on the pill and hoping that helps. 
Anyway, the increase in oil isn't adding up, as the spiro should be decreasing oil. I guess it's possible the oil has nothing to do with the increased spiro dosage, but it seems oddly coincidental. If it is the spiro, how is it even possible? Anyone have this happen or have any insight?

I too have experienced a change in my dosage to 125mg, and it took about 2 1/2-3 months for the new dose to take affect.  On 100mg I still had fairly oily skin and very few breakouts.  Now I am pretty dry on 125mg the last 1 1/2 years.  Hopefully you have given it some time and are seeing a nice balance now.