For anyone that suspects Morgellons:
I have seenRheumatology, Infectious Disease, Dermatology, and Allergy and Immunology.I had the most movement with Immunology, whichled me to Genetic testing. I have never seen Endocrinology, but am very curious about it. Glands and hormones potentially have influence. If anyone has endocrine system tested and it proves significant, please do share.
Immune Issues I have include: low C4, low Mannose Binding Lectin, Low IgG Subunit 2, low Natural Killer Cells, Deficient Functional Natural Killer Cells, High IL 1 Beta.I'd be interested to see if anyone else shares similar.
C4- Immune, complement protein. But AH50 was fine (total amount of all compliment proteins), so diagnostically unsure
Mannose Binding Lectin - Immune, I was at 0 and then 1, normal is 50 or above. Considered Significance Unknown = not enough conclusive research
Low IgG Subunit 2 - Immune, IgG total was fine, there are 4 IgG sub-units.Considered not Diagnostically Significant, but the test was still done for "insight" (?)
Natural Killer Cells (number of cells) - immune, important part of immune, my number wasin a weird middle ground between normal and diagnostically significant. Considered "red flag". Tested multiple times.
Functional Natural Killer Cells (how the cells that you do havefunction) - Immune, important part of immune system. Low, diagnostically significant. You can have completely normal NK Cell numbers and still have a Functional NK Cell Deficiency. However, it willbe more difficult to get a doctor to test for it. NK Cell studies seem to be in infancy, but Covid has prompted many more studies.
High IL 1 Beta - Immune, Interleukins (IL) are Cytokins. Having high IL 1 Beta means my inflammatory response is overactive. That's diagnostically significant, yet not being treated as it is not clear what the mechanismof action is - what is causing it (could be the IL1Beta itself, or precursorproteins such as Monarch 1 Protein, which would be a different medication than IL1Beta medication).
If my immune system allowed an infection/illness/etc. to run rampant, present atypically, and for my body to have a have a hard time overcoming - then treating the source will be important.I have had some genetic testing done and am also in a research study that is doing a full exome. No results untilsummer 2022. I'm told by doc that NK Cell immune issues aredefinitively genetic.
We will eventually find immune similarities. Share if or when you do.