This is another one of the frustrations that comes with taking this medication. A lot of people experience an initial breakout before the benefits and improvements are noticed. Trust me, I've been on it for 3 months already and still get them almost every day still. A lot less frequently than before but I guess because I'm just so prone to acne in the first place, the initial breakout was pretty intense. Five weeks is a good baseline to start seeing some effects but just be patient with it. I was hoping for some sort of miracle, overnight sensation of a cure but as with treating and healing any kind of wound or injury, especially one that can be as severe as cystic type acne, it takes time.