I've never heard of it negatively affecting acne.

Have your skin issues gotten worse since you started working there? As far as I know, simple cold air doesn't really affect acne that much but when there's an insanely cold wind hitting your face, your skin will definitely get irritated. Stale air though... hm, guess it depends on how dry it makes your skin feel. If your skin feels dry, it's probably more prone to react more obviously to scrapes, scratches, etc. than it would in 60-70 degree air.