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[Sticky] Scarless Healing

 
MemberMember
51
(@arte90)

Posted : 08/03/2017 7:36 am

42 minutes ago, JohnRottenSkin said:

can we see a possible succes in their researches according to stock markets? i think it can show us something

2

Insider trading is a criminal activity. You can not make an investment based on information that is not known or accessible to the public. So whether their stock goes up or down, it doesn't really tell you much. Investments are mostly based on speculations.

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MemberMember
151
(@candy-says)

Posted : 08/03/2017 9:37 am

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MemberMember
40
(@anish004)

Posted : 08/03/2017 11:01 am

i also think scarless healing is just a dream.

A substance named decorin help in healing
https://www.fightaging.org/archives/2017/05/decorin-as-a-way-to-reduce-scarring-during-regeneration/

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MemberMember
151
(@candy-says)

Posted : 08/03/2017 11:23 am

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MemberMember
92
(@binga)

Posted : 08/03/2017 11:27 am

2 minutes ago, JohnRottenSkin said:

maybe im not understand it completely, but ok, it can change damaged skin drmatically, but... how can they put it without leaving another scars? they wrote somewhere (facebook as i remember) that it can be applied on WHOLE body. How? can someone explain it? no point to meassage them directly, they will answer you in standart way. We need someone who knows is it possibly can be done? 

But pigs... 3 degree burns... how? why there are no photos of those pigs?;D

 
Check out ACell. They have similar products made from pig skin. 

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MemberMember
151
(@candy-says)

Posted : 08/03/2017 11:45 am

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MemberMember
36
(@mjg713)

Posted : 08/03/2017 12:21 pm

Please stop bringing up Recell, Acell, Epicell, etc. These are already old technologies that have been around. They are NOT the same as Polarity and do NOT result in Scarless Healing. They are just another form of a skin graft. Also, stop differentiating between "Scar-Free Healing" and "Scarless Healing" there is absolutely NO difference, just different wording. Scarless healing does not mean it "Scars less" it means it does not scar at all. Lastly, polarity can not be compared to any previous hyped technologies because it is the first ever to actually completely regenerate porcine skin and show proof of it. None of these previous companies have come this far, that is a huge accomplishment especially considering porcine skin is more complex than human skin. As far as no publicity, I've read plenty of articles regarding the regeneration of porcine skin by Polarity. This obviously won't have optimal publicity until they actually regenerate human skin, which should be completed very soon.

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SunnyX, Candy Says, SunnyX and 3 people reacted
MemberMember
47
(@damnboy)

Posted : 08/03/2017 2:06 pm

i think elastotherapy with tropoelastin will work for strech marks . they are going to finish the cinical trialthis year ... they inject tropoelstin into strech marks and tropoelastin creates NEW elastin fibers and signal fordermis regeneration ...they have already inject tropoelastin into normal healthy skin and they saw that the dermis become thicker....so..... it may Works for strech marks ....F my life bro i am looking for fitness modeling and strech marks on my handand glutes have runied me and you know whati have 9% body fat . F*** LUCk

i cant wait more than 5 f*cking years to fix these strech s***

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MemberMember
3
(@albaneso)

Posted : 08/03/2017 4:23 pm

Any news from polarityTE??

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MemberMember
151
(@candy-says)

Posted : 08/03/2017 6:03 pm

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MemberMember
101
(@slave-of-jesus)

Posted : 08/03/2017 10:13 pm

On Ž09Ž/Ž06Ž/Ž2017 at 11:57 PM, mjg713 said:
On Ž09Ž/Ž06Ž/Ž2017 at 2:27 PM, SunnyX said:

Well before I say soomething 

http://www.polarityte.com/products/skinte

check the third picture, where it says native skin / Margin / skinTe - at margin it indicates a scar between the new and old skin

 

It's hard to tell what exactly the margin is, It could be something so microscopic that the human eye can't tell. Whatever the margin is, SkinTE is still leagues above any current treatment or any foreseeable treatment for the near future, if successful in humans. 

hello mjg713,
What is the margin on the photo? I do not see the margin... it means that skinte, cannot regenerate completely the skin (Scar-Free Healing)  between the new and old skin ? Dsl for my English
 

Polarityte.png.2f82feb9fd9a004ea56c5769626c77b3.png

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MemberMember
24
(@jackdoe)

Posted : 08/03/2017 10:48 pm

Is there any research paper of skinTe?

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MemberMember
40
(@anish004)

Posted : 08/04/2017 3:04 am

ugh life will be so easy without scars
science developed in each field but not in skin dept

ugh life will be so easy without scars
science developed in each field but not in skin dept

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MemberMember
47
(@damnboy)

Posted : 08/04/2017 4:50 am

1.18-1.44 Is this a f*cking joke ? an injectable tropoelastin product has beenmade for atrophic scars as strech marks and acne scars....

2.03-2.10 the doc says the way we can help healingWITHOUT scarring is fantastic

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MemberMember
51
(@arte90)

Posted : 08/04/2017 6:32 am

1 hour ago, damnBOY said:

1.18-1.44 Is this a f*cking joke ? an injectable tropoelastin product has beenmade for atrophic scars as strech marks and acne scars....

2.03-2.10 the doc says the way we can help healingWITHOUT scarring is fantastic

They are currently recruiting subjects for the treatment of acne scars: https://clinicaltrials.gov/ct2/show/NCT03056235?cond=Acne+Scars&draw=1&rank=2

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MemberMember
47
(@damnboy)

Posted : 08/04/2017 6:35 am

1 minute ago, arte90 said:

They are currently recruiting subjects for the treatment of acne scars: https://clinicaltrials.gov/ct2/show/NCT03056235?cond=Acne+Scars&draw=1&rank=2

i know and they are going to finish clinical trial with strech marks

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MemberMember
40
(@anish004)

Posted : 08/04/2017 10:37 am

what is the name of company which is doing trials with tropoelastin ?

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MemberMember
47
(@damnboy)

Posted : 08/04/2017 10:49 am

12 minutes ago, Anish004 said:

what is the name of company which is doing trials with tropoelastin ?

elastagen

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MemberMember
47
(@damnboy)

Posted : 08/04/2017 11:06 am

15 minutes ago, damnBOY said:
28 minutes ago, Anish004 said:

what is the name of company which is doing trials with tropoelastin ?

elastagen

they are referring to regeneration of Human skin soo? will it erase strech marks?

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MemberMember
40
(@anish004)

Posted : 08/04/2017 11:13 am

what is progress of trial ?

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MemberMember
47
(@damnboy)

Posted : 08/04/2017 11:19 am

15 minutes ago, Anish004 said:

what is progress of trial ?

https://www.clinicaltrials.gov/ct2/show/NCT02510768
https://clinicaltrials.gov/ct2/show/NCT03056235

elapr002 is the tropoelastin

Clinical data confirmed biology of tropoelastin based materials, including:

Fibroblast recruitment, collagen deposition and tropoelastin implant remodelling

Increased skin thickness while maintaining natural skin elasticity

Evidence of skin tissue repair properties applicable to treatment of atrophic scars and skin regeneration https://www.mtaa.org.au/sites/default/files/uploaded-content/field_f_content_file/anthony_weiss.pdf check
What do you think?

i will try to call them to learn if tropoelastin erase strech marks completely

+61 2 9209 4054 this is the phone of elastagen in Australia

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MemberMember
17
(@sunnyx)

Posted : 08/04/2017 4:38 pm

3 hours ago, damnBOY said:
https://www.clinicaltrials.gov/ct2/show/NCT02510768
https://clinicaltrials.gov/ct2/show/NCT03056235

elapr002 is the tropoelastin

Clinical data confirmed biology of tropoelastin based materials, including:

Fibroblast recruitment, collagen deposition and tropoelastin implant remodelling

Increased skin thickness while maintaining natural skin elasticity

Evidence of skin tissue repair properties applicable to treatment of atrophic scars and skin regeneration https://www.mtaa.org.au/sites/default/files/uploaded-content/field_f_content_file/anthony_weiss.pdf check
What do you think?

i will try to call them to learn if tropoelastin erase strech marks completely

+61 2 9209 4054 this is the phone of elastagen in Australia

Hi,
dont wonna pull u down. I had actually months ago written to the CEO and the answer I got was that they will release data at the starting of next year. However, I am very sceptical that it can erase scars or stretchmarks, it will only improve them or minimize them. Scars / stretchmarks take place in the dermis. Normal dermis has hairfollicle, sweatglands, nerves, rete ridge, melanin, hypodermis with fatcells etc. and the collagen and elastin bundles are in more basketwoven style. In scar all the above mentioned things are missing and to bridge the gap the body lays down thick collagen bundle in parallel alignment + plus elastin fibers get connected, but everything else is missing. This is why scars and stretchmarks do not have the normal skin texture and color. Only elastin alone is not enough to regenerate the rest of the missing appendixes. We know so far that the wnt pathway is required to activate hair follicle regeneration which will lead to expression of bmp which will transform myofibroblast (scar forming tissue) to turn into fat cells (hypodermis). The wnt pathway can be activated by large wounding (first discovered in 1950) or by expression of fgf9 or LGR6/5/4. The later is done by skinte but this combination has been proven by multiple research groups. So why does elastagen still continue working on Tropoelastin, because it can be used for cosmetic applications instead of Botox and it could be used to fill up small scars, wrinkles and give overall elasticity to the skin. I might be wrong but we might see result next year.

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MemberMember
36
(@mjg713)

Posted : 08/04/2017 5:56 pm

1 hour ago, SunnyX said:
Hi,
dont wonna pull u down. I had actually months ago written to the CEO and the answer I got was that they will release data at the starting of next year. However, I am very sceptical that it can erase scars or stretchmarks, it will only improve them or minimize them. Scars / stretchmarks take place in the dermis. Normal dermis has hairfollicle, sweatglands, nerves, rete ridge, melanin, hypodermis with fatcells etc. and the collagen and elastin bundles are in more basketwoven style. In scar all the above mentioned things are missing and to bridge the gap the body lays down thick collagen bundle in parallel alignment + plus elastin fibers get connected, but everything else is missing. This is why scars and stretchmarks do not have the normal skin texture and color. Only elastin alone is not enough to regenerate the rest of the missing appendixes. We know so far that the wnt pathway is required to activate hair follicle regeneration which will lead to expression of bmp which will transform myofibroblast (scar forming tissue) to turn into fat cells (hypodermis). The wnt pathway can be activated by large wounding (first discovered in 1950) or by expression of fgf9 or LGR6/5/4. The later is done by skinte but this combination has been proven by multiple research groups. So why does elastagen still continue working on Tropoelastin, because it can be used for cosmetic applications instead of Botox and it could be used to fill up small scars, wrinkles and give overall elasticity to the skin. I might be wrong but we might see result next year.

So going by your statement, would you say you have a lot of faith in Polarity's SkinTE Technology?

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MemberMember
40
(@anish004)

Posted : 08/04/2017 11:46 pm

What about Sunogel ? have they ended their project ?

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MemberMember
40
(@anish004)

Posted : 08/05/2017 12:37 am

its been too much waiting for scarless healing .... here we are suffering from scars but dont have any option

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