I have not yet. I will wait about a week before I send a follow up. Has anyone else called or emailed them?

Like I said, this will only work if there's a team effort to contact Gemstone and its affiliates. So far, I think just two of us on this forum have contacted them in the last week.

I'm hesitant to contact them. You see, they're very busy and I think they sort of see this as spamming. I'm curious to find out what they think the hydrogel will be able to do but haven't they sort of already said everything they could on their website?

I don't think they can say anything to people like us that can't either be read on their website or inferred from what is written on their website; they're working on it, the results they have obtained so far have not shown the hydrogel doesn't have the potential to be useful, if it appears in the clinics (i.e. if it will actually be used by plastic surgeons) it can be used for various types of wounds, they are going to test it on people next year... What else can they say?

We'll see I suppose, hopefully sooner rather than later.

http://www.bizjournals.com/baltimore/blog/cyberbizblog/2015/06/baltimore-gemstone-raises-1-6m-to-put-toward-wound.html

Email might nor work. Some body needs to visit them in baltimore to see what they are upto

So, my question is how is it speculated this will work in the end? Dermabrasion + Hydrogel or Ablative Laser Resurfacing + Hydrogel? And would resurfacing be done across the entire face or in sections? To me, removing all epidermal tissue from the face at once sounds a bit...painful. XD

It doesn't matter I think. You just should remove scar tissue. BTW, Seabs wrote that even enzymes can do it. But in this case you can't apply the hydrogel.

It's impossible to excise your entire cheek (for example), it won't heal completely. You need to excise your scars one by one or part by part. The larger a wound, the worse regeneration.

So, my question is how is it speculated this will work in the end? Dermabrasion + Hydrogel or Ablative Laser Resurfacing + Hydrogel? And would resurfacing be done across the entire face or in sections? To me, removing all epidermal tissue from the face at once sounds a bit...painful. XD

Needling with hydrogel might be suffice, Same way as Recell.

"There is big market potential for Gemstone if the company is able to prove its product is not only cheaper but as effective ” if not more so ” than products already available."

As effective as products already available?

http://www.bizjournals.com/baltimore/blog/cyberbizblog/2015/06/baltimore-gemstone-raises-1-6m-to-put-toward-wound.html

Needling with hydrogel might be suffice, Same way as Recell.

Lol, how will it work? Topical use won't help, it's scaffolds that should be placed in a wound.

@lapis I think they be referring to other regenerative medicine competitors such as Avita and their product ReCell. I think by now we've come to realize isn't a very good treatment for acne scarring. If this were the case, this forum would have been loaded with information, before/after results and multiple procedural reviews. I've seen the before and after photos to. I'm not convinced in the least. Not to mention, the procedure is only available overseas and it's ridiculously expensive! Thank goodness it is being developed in the United States.

All of you, do you think that gemstome still aim for scar free wound healing?

All of you, do you think that gemstome still aim for scar free wound healing?

Yup. From the website:

Hydrogel Technology

Hydrogels are polymer-based biomaterials that are extensively used in regenerative medicine applications because they provide three-dimensional scaffolds that simulate the native cell environment and extracellular matrix. Our primary development studies are centered on our novel dextran-based hydrogel for scar-free wound healing. Our hydrogels are produced from original protocols and are highly tunable, meaning they can easily be tailored for specific wound healing applications. The incorporation of biologics, including cells and growth factors, allow for the continuous evolution of our hydrogel systems.

Our hydrogels are produced from original protocols and are highly tunable, meaning they can easily be tailored for specific wound healing applications.

It is also good.

I knew about that roach, but do the still straight or change their mind?

Not to be rude here, but i think what surgeons said about the impossibility of scar free healing is more trustable than gemstone researcher

Because the surgeons are professionals

Read the summary. There are many doctors who state that scar free healing is possible and will be here soon.

They got complete regeneration once, I can see no reasons why they won't get that again. Scar free regeneration is POSSIBLE.

Sure i mean it is possible but those surgeons said its soooo far away

While gemstone seemimgnly being optimistic regarding scar free healing

You saw the paper with your own eyes.

https://drive.google.com/file/d/0BwZi6M9K30AqeDgySU9jVGNickE/view?usp=sharing

They're damn near close. Even if they won't achieve complete regeneration, I'm sure it can help us anyway. Yesterday we talked about that. Remember?

Its in a mouse, Roach

But in a pig it completely restored rete ridges and epidermis.

I hope so Roach

I know how you feel, Rudy. I feel the same. But let's believe in facts. I like Seabs because he ain't blinded by optimism, he makes statements only on the basis of facts, so should we.

BTW, there are many companies that will be able to synthesize the CAR-Decorin (which more effective than native decorin and inhibits TGF-B 1 and 2 completely, but doesn't inhibit TGF-B3)

1 more question roach...

Do you think we will ever regain our original skin in the future?

Your opinion is i want to hear

I think it depends of the level of damage. Probably we won't get our skins back like they were before (a bit uneven surface, for example), but I'm sure we'll get the greatest improvement. Although, if something claims complete regeneration it means we'll get new skin.

I wouldn't put all on the hydrogel. I'm looking for a multipronged approach. You know I've found a doc and I'm gonna show him a lot of papers, but I need more info about the hydrogel.

http://www.sec.gov/Archives/edgar/data/1191357/000122150807000051/ex99_2anticytcokine.html

I wonder if JHU could use the findings from this to improve the Hydrogel?

It works by suppressing "Cytokines" during wound recovery. They used an Arthritis Cream from Australia called Thermalife. It has bovine collagen in it.