hydrogel.
hahaha @maldition i keep seeing these random posts from you. are you trying to move us up in the google search results?
if this hydrogel could really promote scarless healing it would FUCKING REVOLUTIONARY --like one of the most significant medical/scientific findings of ALL TIME --and this is why I'm pretty skeptical that it actually works, it would have been mainstreamed, replicated, applied to humans SOMEWHERE in the world a long, long time ago already.
But you know, let see...
lol I'm skeptical too. As it would indeed be something. But there is a firm belief within the medical world that it (i.e. scarless healing) will come to fruition. So why couldn't it be this hydrogel which is showing real promise (for whatever that's worth)?
hydrogel.
No funding,no hydrogel.If there is funding, there is still IP issue.I give up
IP issue?
if this hydrogel could really promote scarless healing it would FUCKING REVOLUTIONARY --like one of the most significant medical/scientific findings of ALL TIME --and this is why I'm pretty skeptical that it actually works, it would have been mainstreamed, replicated, applied to humans SOMEWHERE in the world a long, long time ago already.
But you know, let see...
lol I'm skeptical too. As it would indeed be something. But there is a firm belief within the medical world that it (i.e. scarless healing) will come to fruition. So why couldn't it be this hydrogel which is showing real promise (for whatever that's worth)?
>
hydrogel.
No funding,no hydrogel.If there is funding, there is still IP issue.I give up
IP issue?
Someone in previous post mentioned it
if this hydrogel could really promote scarless healing it would FUCKING REVOLUTIONARY --like one of the most significant medical/scientific findings of ALL TIME --and this is why I'm pretty skeptical that it actually works, it would have been mainstreamed, replicated, applied to humans SOMEWHERE in the world a long, long time ago already.
But you know, let see...
It has. It produced complete regeneration (scar free healing). The hydrogel degraded in under seven days and complete regeneration occured, the control behaved typically and scarred.
have motivated the users into the Facebook page and to investigate ... but that should be just the beginning, they should not give up.
hydrogel.
hahaha @maldition i keep seeing these random posts from you. are you trying to move us up in the google search results?
Have motivated the users into the Facebook page and to investigate ... but that should be just the beginning, they should not give up.
hydrogel.
No funding,no hydrogel.If there is funding, there is still IP issue.I give up
Do not give up, it is better to have a hope, or in the latter case ... live in the escape, I mean, take your mind anything to get away. but do not give up....
have motivated the users into the Facebook page and to investigate ... but that should be just the beginning, they should not give up.
hydrogel.
hahaha @maldition i keep seeing these random posts from you. are you trying to move us up in the google search results?
Have motivated the users into the Facebook page and to investigate ... but that should be just the beginning, they should not give up.
>hydrogel.
No funding,no hydrogel.If there is funding, there is still IP issue.I give up
Do not give up, it is better to have a hope, or in the latter case ... live in the escape, I mean, take your mind anything to get away. but do not give up....
well, I don't give up hope, but this hydrogel, as JHU stopped working on this...
200 PAGES NOW.
AND NO SOLUTION.
I'M WAIT FOR THE MIRACLE.
By the way, correct English would be "I'm waiting for the miracle".
Anyway, I've quoted this somewhat old post by maldition as I saw it when was looking through the last few pages trying to find out what the IP issue is but couldn't find anything.
Maldition if this hydrogels fails then something else will succeed, you need to build a larger picture in your mind, regenerative medicine has to solve the problem of tissue scarring - otherwise spinal cord injuries and heart damage after a heart attack will remain incurable forever, I just can't imagine that scenario, it is simply not possible.
Read this:
http://ijl.sagepub.com/content/11/4/264.abstract
A mixture of hUC-MSCs, Whartons jelly, and skin microparticles were transplanted to 10-mm diameter, full-thickness, middorsal, excisional skin wounds of mice. After 7 days, the tissue sections were sampled for reconstruction analysis and histological examination. After transplantation, there was a remarkable development of newborn skin and its appendages. We could see newly generated layers of epidermis, sebaceous glands, hair follicle, and sweat glands clearly. This innovative strategy could be very promising and may significantly increase the quality of repair and regeneration of skin in injuries.
And look at this graph, it shows the number of publications related to regenerative medicine in the United States from 1984 to 2009.
Figure 2.
The number of publications in every single year from 1984 to the end of 2009.
Anyway, I've quoted this somewhat old post by maldition as I saw it when was looking through the last few pages trying to find out what the IP issue is but couldn't find anything.
IP issue = intellectual property issue.
Maldition if this hydrogels fails then something else will succeed, you need to build a larger picture in your mind, regenerative medicine has to solve the problem of tissue scarring - otherwise spinal cord injuries and heart damage after a heart attack will remain incurable forever, I just can't imagine that scenario, it is simply not possible.
Read this:
http://ijl.sagepub.com/content/11/4/264.abstract
A mixture of hUC-MSCs, Whartons jelly, and skin microparticles were transplanted to 10-mm diameter, full-thickness, middorsal, excisional skin wounds of mice. After 7 days, the tissue sections were sampled for reconstruction analysis and histological examination. After transplantation, there was a remarkable development of newborn skin and its appendages. We could see newly generated layers of epidermis, sebaceous glands, hair follicle, and sweat glands clearly. This innovative strategy could be very promising and may significantly increase the quality of repair and regeneration of skin in injuries.
And look at this graph, it shows the number of publications related to regenerative medicine in the United States from 1984 to 2009.
>>Figure 2.
The number of publications in every single year from 1984 to the end of 2009.
Anyway, I've quoted this somewhat old post by maldition as I saw it when was looking through the last few pages trying to find out what the IP issue is but couldn't find anything.
IP issue = intellectual property issue.
+10
The statistic that is very positive and put your message is clear example of that is to proceed, it is an example for people who have no hope read (many users unregistered are in depression and come to read). Thanks for your input Vladislad really is valuable.
I wonder how many people here this treatments or finish in time to treatment for anxiety or depression or illness because of depression because of the stress caused by having scars, low self esteem lower the body's defenses ...
edit: nevermind
about my write, while stop worrying about spelling here, i don't care.
I just thought you might like to learn some English along the way. No harm intended.
IP issue = intellectual property issue.
Thank you!
I thought it might have had something to do with IP adresses. lol
The statistic that is very positive and put your message is clear example of that is to proceed, it is an example for people who have no hope read (many users unregistered are in depression and come to read). Thanks for your input Vladislad really is valuable.
I wonder how many people here this treatments or finish in time to treatment for anxiety or depression or illness because of depression because of the stress caused by having scars, low self esteem lower the body's defenses ...
I don't have any of those problems, not anymore, sometimes I feel fucked up but I quickly recover my mind and everything turns back to normal, what kind of scars do you have, acne scars or injury scars? If you have acne scars I would say that the solution could be ReCell, I can see that this guy has achieved very good results with ReCell:
He claims 75% improvement and I remember that I have read that he is now working as a management consultant, probably earning $100,000+ a year, he has a career, girlfriend, life, he has everything.
If you have acne scars I would say that the solution could be ReCell, I can see that this guy has achieved very good results with ReCell:He claims 75% improvement and I remember that I have read that he is now working as a management consultant, probably earning $100,000+ a year, he has a career, girlfriend, life, he has everything.
I don't mean to rain on anyone's parade but his case is controversial. Plus the man who treated him has been sued for pressuring his employees into getting surgery. Just something to keep in mind.
I don't know, I'm not familiar with all the details, I know that many doctors are scumbag quacks.
Anyway read this, the next breakthrough in regenerative medicine could be a solution for spinal cord injuries (spinal cord scarring):
http://seekingalpha.com/article/1112911-the-race-to-cure-spinal-cord-injuries?source=yahoo
The Race To Cure Spinal Cord Injuries
January 15, 2013 | 24 comments | includes: CUR, NVIV.OB, STEM
...
Following a SCI, the nerve cells below the level of injury become disconnected from the brain. This is due to scar tissue which forms in the structure of the damaged area of the spinal cord, blocking messages from the brain to below the level of injury.
I don't know, I'm not familiar with all the details, I know that many doctors are scumbag quacks.
Anyway read this, the next breakthrough in regenerative medicine could be a solution for spinal cord injuries (spinal cord scarring):
http://seekingalpha.com/article/1112911-the-race-to-cure-spinal-cord-injuries?source=yahoo
The Race To Cure Spinal Cord Injuries
January 15, 2013 | 24 comments | includes: CUR, NVIV.OB, STEM
...
Following a SCI, the nerve cells below the level of injury become disconnected from the brain. This is due to scar tissue which forms in the structure of the damaged area of the spinal cord, blocking messages from the brain to below the level of injury.
Some say Ernestoria from that thread you linked to was in cahoot with Khan, in an effort to lure people here to his clinic. But who's to say?
Anyway, thanks for the interesting link.
i hate to burst the bubble on this fundraising initiative, but don't you think that if the scientists demonstrated that this hydrogel technique showed real promise there'd be like a world of venture capitalists and investors begging to be a part of this?
rez77 very true which is why ive been thinking that spreading the word is the key here. Getting the right people interested. I figured maybe not enough people know? that could just be my naive view of it all too.
or are you saying maybe there is perhaps no real promise in the research?
trust me brother, if something comes of this, no one would be happier than me, and so I applaud your efforts. But the people to ask would be the docs who performed the experiment. i can't read this whole thread.
if this hydrogel could really promote scarless healing it would FUCKING REVOLUTIONARY --like one of the most significant medical/scientific findings of ALL TIME --and this is why I'm pretty skeptical that it actually works, it would have been mainstreamed, replicated, applied to humans SOMEWHERE in the world a long, long time ago already.
But you know, let see...
We've had the discussion about venture capitalists and investors before on the thread. Like you, I thought that they would come running.
However, I was wrong and someone corrected me. At this stage in the game it's far too early for them to be interested. So many factors contributing to this.
One, it's only been tested on mice so you'd be funding R&D that's unproven in other mammals and with no clear path to market. Investors like to make money.
Two, JHU themselves have said they don't really understand how they got the results they obtained.
Three, there are a whole host of scam artists out there that have probably made investors extremely uneasy and dubious about spending their money in this market (Renovo for example).
Four, it seems like there are IP issues so until that's settled I can't imagine anyone even being able to consider investing. Investors want a return on their investment and if the IP isn't settled they don't know if their 5% return is going to be with someone who owns the patent outright, owns 50% or owns 0% in the end. You wait to place a bet until you're as sure as you can be that the horse is going to be the winner. And on top of all of that no one knows for sure if it will work in humans anyway.
Dr. Sun didn't quite, the funding for his position ran out per his conversation with chuckstonchew. Who knows though, the IP issue might have had something to do with it. Dr. Gerecht and Dr. Harmon are still at JHU with Dr. Harmon working hard to get the ball rolling.
It's hard to find a reason to believe that this is a scam at this particular juncture. All JHU has done is tested the hydrogel and had their findings vetted for publication in a medical journal. If we help with this through indiegogo we should all be aware of the very real possibility that it won't work. That's not being scammed, that's making an informed decision and recognizing the possible outcomes. Right now I have no reason to doubt their intentions and the possibilities of the hydrogel and I don't think anyone else really does either.
i hate to burst the bubble on this fundraising initiative, but don't you think that if the scientists demonstrated that this hydrogel technique showed real promise there'd be like a world of venture capitalists and investors begging to be a part of this?
rez77 very true which is why ive been thinking that spreading the word is the key here. Getting the right people interested. I figured maybe not enough people know? that could just be my naive view of it all too.
or are you saying maybe there is perhaps no real promise in the research?
trust me brother, if something comes of this, no one would be happier than me, and so I applaud your efforts. But the people to ask would be the docs who performed the experiment. i can't read this whole thread.
if this hydrogel could really promote scarless healing it would FUCKING REVOLUTIONARY --like one of the most significant medical/scientific findings of ALL TIME --and this is why I'm pretty skeptical that it actually works, it would have been mainstreamed, replicated, applied to humans SOMEWHERE in the world a long, long time ago already.
But you know, let see...
We've had the discussion about venture capitalists and investors before on the thread. Like you, I thought that they would come running.
However, I was wrong and someone corrected me. At this stage in the game it's far too early for them to be interested. So many factors contributing to this.
One, it's only been tested on mice so you'd be funding R&D that's unproven in other mammals and with no clear path to market. Investors like to make money.
Two, JHU themselves have said they don't really understand how they got the results they obtained.
Three, there are a whole host of scam artists out there that have probably made investors extremely uneasy and dubious about spending their money in this market (Renovo for example).
Four, it seems like there are IP issues so until that's settled I can't imagine anyone even being able to consider investing. Investors want a return on their investment and if the IP isn't settled they don't know if their 5% return is going to be with someone who owns the patent outright, owns 50% or owns 0% in the end. You wait to place a bet until you're as sure as you can be that the horse is going to be the winner. And on top of all of that no one knows for sure if it will work in humans anyway.
Dr. Sun didn't quite, the funding for his position ran out per his conversation with chuckstonchew. Who knows though, the IP issue might have had something to do with it. Dr. Gerecht and Dr. Harmon are still at JHU with Dr. Harmon working hard to get the ball rolling.
It's hard to find a reason to believe that this is a scam at this particular juncture. All JHU has done is tested the hydrogel and had their findings vetted for publication in a medical journal. If we help with this through indiegogo we should all be aware of the very real possibility that it won't work. That's not being scammed, that's making an informed decision and recognizing the possible outcomes. Right now I have no reason to doubt their intentions and the possibilities of the hydrogel and I don't think anyone else really does either.
I don't want to sound too negative, and I definitely don't know all the ins and outs of how projects like this are funded etc.. But my common sense says the following. All this technology involved was creating an injury in a mouse and then covering it with this hydrogel substance and allowing it to heal, voila, scarless healing. They should at least be able to replicate this result a hundred times without any need for major funding. Have they been able to do that? I don't know I'm asking, or was it just a one-off? If they've been able to replicate the results in mice predictably then it should be fairly corroborated that the technique works, right?
I mean the implications for this are FAR BEYOND acne scarring --indeed ANY operation procedure or injury would benefit. This invention would make its developers the richest people in the world potentially. This is why I'm skeptical that if it really worked they're not doing anything they can to jump on it. I would be satisfied at this stage to even learn that it's replicable in mice. Is it?
@rez77 gotta say i agree with you. i would like to know if this regeneration was replicated too. and to do so would not require funding. Im still wondering how pig testing requires large funding. and if its as amazing as we are all thinking i dont see how they were able to sweep it under the carpet. Im not doubting the research, just wondering if its less straightforward than we are imagining.
@rez77 gotta say i agree with you. i would like to know if this regeneration was replicated too. and to do so would not require funding. Im still wondering how pig testing requires large funding. and if its as amazing as we are all thinking i dont see how they were able to sweep it under the carpet. Im not doubting the research, just wondering if its less straightforward than we are imagining.
I talked to a friend who has animal research experience. Keeping a mouse in the animal house will only cost one dollar a day, but keeping a pig will probably cost 50 dollars a day. Say you keep one pig for 30 days, you will need 1500 for just keeping them alive in the animal house. If you want to other surgery, it will cost much more......
i hate to burst the bubble on this fundraising initiative, but don't you think that if the scientists demonstrated that this hydrogel technique showed real promise there'd be like a world of venture capitalists and investors begging to be a part of this?
rez77 very true which is why ive been thinking that spreading the word is the key here. Getting the right people interested. I figured maybe not enough people know? that could just be my naive view of it all too.
or are you saying maybe there is perhaps no real promise in the research?
trust me brother, if something comes of this, no one would be happier than me, and so I applaud your efforts. But the people to ask would be the docs who performed the experiment. i can't read this whole thread.
if this hydrogel could really promote scarless healing it would FUCKING REVOLUTIONARY --like one of the most significant medical/scientific findings of ALL TIME --and this is why I'm pretty skeptical that it actually works, it would have been mainstreamed, replicated, applied to humans SOMEWHERE in the world a long, long time ago already.
But you know, let see...
We've had the discussion about venture capitalists and investors before on the thread. Like you, I thought that they would come running.
However, I was wrong and someone corrected me. At this stage in the game it's far too early for them to be interested. So many factors contributing to this.
One, it's only been tested on mice so you'd be funding R&D that's unproven in other mammals and with no clear path to market. Investors like to make money.
Two, JHU themselves have said they don't really understand how they got the results they obtained.
Three, there are a whole host of scam artists out there that have probably made investors extremely uneasy and dubious about spending their money in this market (Renovo for example).
Four, it seems like there are IP issues so until that's settled I can't imagine anyone even being able to consider investing. Investors want a return on their investment and if the IP isn't settled they don't know if their 5% return is going to be with someone who owns the patent outright, owns 50% or owns 0% in the end. You wait to place a bet until you're as sure as you can be that the horse is going to be the winner. And on top of all of that no one knows for sure if it will work in humans anyway.
Dr. Sun didn't quite, the funding for his position ran out per his conversation with chuckstonchew. Who knows though, the IP issue might have had something to do with it. Dr. Gerecht and Dr. Harmon are still at JHU with Dr. Harmon working hard to get the ball rolling.
It's hard to find a reason to believe that this is a scam at this particular juncture. All JHU has done is tested the hydrogel and had their findings vetted for publication in a medical journal. If we help with this through indiegogo we should all be aware of the very real possibility that it won't work. That's not being scammed, that's making an informed decision and recognizing the possible outcomes. Right now I have no reason to doubt their intentions and the possibilities of the hydrogel and I don't think anyone else really does either.
I don't want to sound too negative, and I definitely don't know all the ins and outs of how projects like this are funded etc.. But my common sense says the following. All this technology involved was creating an injury in a mouse and then covering it with this hydrogel substance and allowing it to heal, voila, scarless healing. They should at least be able to replicate this result a hundred times without any need for major funding. Have they been able to do that? I don't know I'm asking, or was it just a one-off? If they've been able to replicate the results in mice predictably then it should be fairly corroborated that the technique works, right?
I mean the implications for this are FAR BEYOND acne scarring --indeed ANY operation procedure or injury would benefit. This invention would make its developers the richest people in the world potentially. This is why I'm skeptical that if it really worked they're not doing anything they can to jump on it. I would be satisfied at this stage to even learn that it's replicable in mice. Is it?
Broken record time, my apologies... They havent replicated it beyond this scope yet, as they are following a code of ethics no doubt. But it has been replicated and can be replicated again and again as it is a factual document, there is nothing hidden. Any scholar with curiosity could replicate this easily. BTW the only way this would not work, going on the logic in the paper is if, the formula was changed, like say the speed of digestion was slowed down and the porosity was changed (e.g a 60:40 ratio porosity instead of a 8020, or the hydrogel and so on). Also by logic, all scaffolds do is degrade in mammals; they behave the same in all mammals they cannot discriminate. With regards to this wait for funding, I have been like you are for over a year. This needs funding.
i hate to burst the bubble on this fundraising initiative, but don't you think that if the scientists demonstrated that this hydrogel technique showed real promise there'd be like a world of venture capitalists and investors begging to be a part of this?
rez77 very true which is why ive been thinking that spreading the word is the key here. Getting the right people interested. I figured maybe not enough people know? that could just be my naive view of it all too.
or are you saying maybe there is perhaps no real promise in the research?
trust me brother, if something comes of this, no one would be happier than me, and so I applaud your efforts. But the people to ask would be the docs who performed the experiment. i can't read this whole thread.
if this hydrogel could really promote scarless healing it would FUCKING REVOLUTIONARY --like one of the most significant medical/scientific findings of ALL TIME --and this is why I'm pretty skeptical that it actually works, it would have been mainstreamed, replicated, applied to humans SOMEWHERE in the world a long, long time ago already.
But you know, let see...
We've had the discussion about venture capitalists and investors before on the thread. Like you, I thought that they would come running.
However, I was wrong and someone corrected me. At this stage in the game it's far too early for them to be interested. So many factors contributing to this.
One, it's only been tested on mice so you'd be funding R&D that's unproven in other mammals and with no clear path to market. Investors like to make money.
Two, JHU themselves have said they don't really understand how they got the results they obtained.
Three, there are a whole host of scam artists out there that have probably made investors extremely uneasy and dubious about spending their money in this market (Renovo for example).
Four, it seems like there are IP issues so until that's settled I can't imagine anyone even being able to consider investing. Investors want a return on their investment and if the IP isn't settled they don't know if their 5% return is going to be with someone who owns the patent outright, owns 50% or owns 0% in the end. You wait to place a bet until you're as sure as you can be that the horse is going to be the winner. And on top of all of that no one knows for sure if it will work in humans anyway.
Dr. Sun didn't quite, the funding for his position ran out per his conversation with chuckstonchew. Who knows though, the IP issue might have had something to do with it. Dr. Gerecht and Dr. Harmon are still at JHU with Dr. Harmon working hard to get the ball rolling.
It's hard to find a reason to believe that this is a scam at this particular juncture. All JHU has done is tested the hydrogel and had their findings vetted for publication in a medical journal. If we help with this through indiegogo we should all be aware of the very real possibility that it won't work. That's not being scammed, that's making an informed decision and recognizing the possible outcomes. Right now I have no reason to doubt their intentions and the possibilities of the hydrogel and I don't think anyone else really does either.
I don't want to sound too negative, and I definitely don't know all the ins and outs of how projects like this are funded etc.. But my common sense says the following. All this technology involved was creating an injury in a mouse and then covering it with this hydrogel substance and allowing it to heal, voila, scarless healing. They should at least be able to replicate this result a hundred times without any need for major funding. Have they been able to do that? I don't know I'm asking, or was it just a one-off? If they've been able to replicate the results in mice predictably then it should be fairly corroborated that the technique works, right?
I mean the implications for this are FAR BEYOND acne scarring --indeed ANY operation procedure or injury would benefit. This invention would make its developers the richest people in the world potentially. This is why I'm skeptical that if it really worked they're not doing anything they can to jump on it. I would be satisfied at this stage to even learn that it's replicable in mice. Is it?
Broken record time, my apologies... They havent replicated it beyond this scope yet, as they are following a code of ethics no doubt. But it has been replicated and can be replicated again and again as it is a factual document, there is nothing hidden. Any scholar with curiosity could replicate this easily. BTW the only way this would not work, going on the logic in the paper is if, the formula was changed, like say the speed of digestion was slowed down and the porosity was changed (e.g a 60:40 ratio porosity instead of a 8020, or the hydrogel and so on). Also by logic, all scaffolds do is degrade in mammals; they behave the same in all mammals they cannot discriminate. With regards to this wait for funding, I have been like you are for over a year. This needs funding.
Hey, could you do me a favor? Could you just message me whenever there is any actual development on this or the possibility for a real cure for acne scarring? I've waited for this now for what feels like several years. I have bad scarring and I need a cure, but I'm wasting my life away constantly looking at these forums and updates for the newest thing and they never arrive. Id appreciate it my friend if whenever something truly helpful is developed you might message me. Thank you.