However, if we had the scar in the first place, is it possible to somehow reverse it and cause the body to regenerate normal tissues instead of scarring.
I think that scarless regeneration of existing scarred tissue will be reliant upon a "re-injuring" the skin in some type of fashion. You would cause a new controlled injury, starting the process over again, and then begin redirecting healing and regeneration from that point on (utlizing whatever scarless healing technology becomes available).
The theory is sound and very plausible. Keep in mind through that the outcome is dependent upon the process, ie- the healing phase. You would have to initiate the healing phase. The initiation of the healing process is obviously contingent upon the creation of a new wound.
This is how I see it playing out.
This is exactly what is behind the theory and practice of the Fraxel Laser. The skin/scar is injured thousands of times at the microscopic level. Then the body naturally heals each microscopic wound by regeneration.
The body naturally heals any wound as small, or smaller, than a paper-cut by regeneration. Anything bigger tends to heal by repair (AKA scarring or healing by primary, secondary intentions).
The only problem with Fraxel is that it's fractional. So the process is slow and and imprecise. Also expensive and a commitment to treatment.
In the future, I'm not sure how scar treatment will change. I'm not sure I can ever imagine doctor's cutting out whole scars by the inch. Even if they are replaced by skin grafts and healing factors, it would be a messy procedure. The body just doesn't work like that.
I guess based on that, in the future, the scar treatments out there will be based on encouraging the body to slowly catabolize scar tissue and remodel itself.
With the ablative fractional laser out now, like Fraxel Re:Pair and Active FX, we are suprisingly close to this technology. Scar tissue can be vaporized very effectively in a fractional manner. Then regeneration follows.
The only problem with ablative fractional lasers are the "shrinkage" or loss of tissue that happens. Also the loss of skin structures like sweat glands, nerves, hair follicles, etc. I suspect in the future we will combine these procedures with stem cell therapy that encourages the body to create new skin structures, not just new collagen.
However, if we had the scar in the first place, is it possible to somehow reverse it and cause the body to regenerate normal tissues instead of scarring.
I think that scarless regeneration of existing scarred tissue will be reliant upon a "re-injuring" the skin in some type of fashion. You would cause a new controlled injury, starting the process over again, and then begin redirecting healing and regeneration from that point on (utlizing whatever scarless healing technology becomes available).
The theory is sound and very plausible. Keep in mind through that the outcome is dependent upon the process, ie- the healing phase. You would have to initiate the healing phase. The initiation of the healing process is obviously contingent upon the creation of a new wound.
This is how I see it playing out.
I agree. If this Acell stuff can really tell a finger tip to grow back ...if this is the answer to our problem I see this as the solution to the problem:
Patient will get will have an ablative procedure on the scar, whether it be laser or dermabrasion. The ablation will go deep down to the dermis so much so that the scar tissue is completely destroyed.
The Acell powder will be put on the wound and it will be properly dressed.
If it takes 4 weeks for half an inch of finger to grow back ...my hope would be that the patient would be completely healed and regenerated in 1 week, with no redness. Acell bandages would still be used for some time to ensure regeneration is complete, after all it is your face!
Possible side effects may include new or different moles or freckles. Also beard hairs may grow faster than existing hairs.
EEEK. I've never not wanted to cut military funding so badly!!!!
Scar free healing...
here is a link,
http://www.cbsnews.com/sections/i_video/ma...tml?id=3805429n
he mentions
that scarring is a brick wall to regeneration and that this matrix enables the enzymes that stop the wound from having a scar respone, thus enabling regeneration.
Here is the link to the article and you will see there is another video...
http://www.cbsnews.com/stories/2008/02/07/...in3805318.shtml
I think Scarcrash answered for me perfectly.
Using this technology that this man used to regenerate his tip without fibrosis IMO the first technology will be as Scarcrash said to reinjure in a controlled fashion, eg, cut out a spot or another scar --> apply the powder repeated at certain times in a controlled fashion, over a certain time structure, until the regeneration is finished. Also I think if you used this on a skin scar you could have regeneration much quicker than him regenerating his bony, vascular, fleshy finger tip.
Anyway clearly: that man has had scar free healing...
I think Scarcrash answered for me perfectly.
Using this technology that this man used to regenerate his tip without fibrosis IMO the first technology will be as Scarcrash said to reinjure in a controlled fashion, eg, cut out a spot or another scar --> apply the powder repeated at certain times in a controlled fashion, over a certain time structure, until the regeneration is finished. Also I think if you used this on a skin scar you could have regeneration much quicker than him regenerating his bony, vascular, fleshy finger tip.
Anyway clearly: that man has had scar free healing...
Yes, but what if the scars are acne scars? Wouldnt it be too risky to cut out scars on your face and apply the powder hoping for regeneration? It sounds very risky, although proven to work on a fingertip.
I think Scarcrash answered for me perfectly.
Using this technology that this man used to regenerate his tip without fibrosis IMO the first technology will be as Scarcrash said to reinjure in a controlled fashion, eg, cut out a spot or another scar --> apply the powder repeated at certain times in a controlled fashion, over a certain time structure, until the regeneration is finished. Also I think if you used this on a skin scar you could have regeneration much quicker than him regenerating his bony, vascular, fleshy finger tip.
Anyway clearly: that man has had scar free healing...
Yes, but what if the scars are acne scars? Wouldnt it be too risky to cut out scars on your face and apply the powder hoping for regeneration? It sounds very risky, although proven to work on a fingertip.
A scar is a scar. I reckon if you cut out the brick wall completely, and if you follow the instructions and apply the stuff it should work for an acne mark as much as a full thickness scar.
I am guardedly optimistic about A-Cell and we all had this conversation about nine months ago. The fingertip is one of those areas that actually has been known to regenerate on its own without any intervention, so it isn't an ideal litmust test of efficacy. I think it will be useful as a wound dressing, but I don't think it will necessarily serve our purpose of perfectly regenerating our lost tissue. I read somewhere, back when I was researching this substance heavily, that they were thinking of mixing it in with Restylane to make a much more effective and long lasting filler. That could be helpful... We will see!
The fingertip is one of those areas that actually has been known to regenerate on its own without any intervention, so it isn't an ideal litmust test of efficacy.
Absolutely, Anna. Did they really attempt to analyze the regenerative capacity of acell by testing on an amputated fingertip? This is the last body part that should have been selected to obtain an accurate assessment of the potential efficacy of this product.
Stories of fingertip regeneration are quite common and have occurred in a wide array of age groups. Instances of fingertip regeneration have been attibuted to everything from pig bladder extract, herbal pastes, electric current stimulation, and even...nothing at all.
Regeneration recipe: Pinch of pig, cell of lizard
"Thereas the guy who sliced off a fingertip but grew it back, after he treated the wound with an extract of pig bladder...This summer, scientists are planning to see whether the powdered pig extract can help injured soldiers regrow parts of their fingers...Spievack said itas a little hard, as if calloused, and thereas a slight scar on the end. The nail continues to grow at twice the speed of his other nails."
Associated Press
"Finger Regeneration: Once, when at a convention in the Northwest, a beautiful young lady came up to Dr. Christopher and his son, David. "How do you like my fingers?", she asked. They were well taken care of and the nails were done nicely. Dr. Christopher said, "Fine," and she asked, "Can you tell which finger has been cut off?" They couldn't tell. She showed him the finger that had been cut off; she used the BF & C, and the knuckle grew back, and the bone and flesh grew back in. The nail, which had been completely gone, grew back on, as pretty as the others. This was a truly unusual case of healing."
"Bone Flesh and Cartilage" by Dr. John R. Christopher
Newsletter: Vol. 4 Issue 8e
Fingertip regeneration with Electrical Stimulation
"For example, Figure 8 depicts a human finger which has been amputated just above the first knuckle. Platinum plated stainless steel acupuncture needles have been inserted directly behind the amputation site a few days or so after the amputation. It is the ion concentrations that are the missing critical factor. And the ion concentrations required for blastema formation and maintenance should be about the same for all mammals...The acupuncture needles must be kept relatively close behind the advancing blastema, until full regeneration has been achieved."
A Physicist's View of the Use of Feeble Electric Direct Currents To Repair Tissue and Replace Body Partsby Gary Wade
www.rifeenergymedicine.com
A report from National Institute of Child Health and Human Development concerning fingertip regeneration:
Regeneration of Digit Tip
"There are few documented instances in which human organs are able to respond to injury by complete and perfect replacement the damaged parts. One such case is the tip of the finger,which can regenerate under appropriate conditions, even in adults. Fingertip regeneration is a relatively understudied phenomenon, despite the fact that the most frequent body part injured is the hand, and that approximately 19,000 people in the U.S. experience loss of a digit in any one year. The human digit is composed of diverse tissues, such as epidermis, nail, nailbed, dermis, adipose, and bone. Upon amputation, the digit can recreate a perfect replica of its tip, including the nail and fingerprint, without the deposition of scar tissue. This regeneration response is level specific: it only occurs following amputations at or distal to the level of the nailbed. Amputations just proximal to the nailbed result in scar tissue formation and incomplete regeneration. Using molecular and histological techniques, NCMRR-funded researchers are using digit amputation in mammals as a model system to study both organ regeneration and scar-free wound healing. Molecular studies have focused on two developmental genes, Msx1 and Msx2, that are re-expressed in the damaged nailbed tissue at the site of the wound and may have a key role in the regeneration process. Another approach is to study digit regeneration in mice that have these particular homeobox-containing genes knocked out. Other studies examine the interactions among particular cells and the extracellular matrix to determine whether digit regeneration recapitulates the initial limb development process, or whether it represents a special form of hyperplasia of differentiated tissues. Taken together, these studies will provide the motivation for more systematic studies of digit regeneration. This work also shows promise forregulating growth both at amputation sites, and in internal organs."
National Institute of Child Health and Human Development
www.nichd.nih.gov
It seems that finger regeneration depends on the regenerative capacity of the cells within the nail bed and the proximity of the wound to those cells. This might explain why Spievack's nail on the regenerated finger continued to grow at twice the rate of his other nails. It's interesting that even after the regeneration, he still had a scar.
Ultimately, the fingertip regeneration observed in the acell trial seemingly has more to due with the fingertip's inherent regenerative capability, than the acell itself.
Interesting...
Anyone translate Japanese? This is some good histology of fraxel causing regeneration.
Actually, anyone who has MS Word can translate. All you need to do is paste the script into a Word document and then highlight it and then select Tools, then Language, and then Translate. Your computer might then need to download Japanese and the other Asian languages as mine did. This is the translation of the first part. It isn't perfect but it is good enough to give you a clear sense of what they are saying. Kind of entertaining is some parts..."Take the blotch to make Hari ":
Take the blotch, to make Hari the skin recover as for the former laser in order, the lighting beam centimeter,
It means that the fact that it is diameter of the millimeter unit is common sense, but as for [hurakuseru] the lighting beam of the laser the micro unit
It tried to be able to remedy new type in (by in fact point) reducing, epoch making
It is the laser remedy vessel.This remedy is developed at the 0 0N Harvard University well man laboratory,
Fractional PhotothermolysisWith it was designated
Until recently as the remedy which solves the general problem of the skin surface such as blotch being somber skin quality, with law the most effective one
CO2Uses the laser the [risahueshingu] remedy (one time peeling skin with laser, method of replacing completely) which
Is.CO2As for the laser, in representation of [abureiteibu] laser which deprives the epidermis, the skin in the surface [risahueshingu]
It is to do, but as for [hurakuseru] the skin the dot of minimum(Point)So it is the remedy vessel which [risahueshingu] is done.Not to be the surface, in the point
The fact that it remedies is the [hurakuseru] largest point.Certainly [abureiteibu] which the whole skin [risahueshingu] is done
As for technique1It is with the time to be able to designate wide scope as the remedy target, but because the whole epidermis is exfoliated surgically, several months
The long-term downtime which reaches and infection, there was a problem of the side effect complication such as pigmentation.[hurakuseru]
Because [risahueshingu] in the point preserves the horny layer which has the barrier function of the skin surface completely, risk
You evade, also the make-up and the [hige] shaving from immediately after the remedying are possible remedy.Actually2£3As for redness and the like of day a certain thing every day
It is healing in no downtime or minimum downtime in life,1Depending on remedy of time12¯½Å¾20% Skin
It is possible to replace.As for remedy region, as for face of course thing, with [abureiteibu] remedy healing
It made also the correspondence to the shell and the like of the difficult neck and decollete and hand possible.Furthermore, as for frequency of remedy4¯½Å¾6With time Japanese
As for the remedy interval which is agreeable to the skin4It is made the week.
[Efficiency of [hurakuseru]]
Anna said,
I am guardedly optimistic about A-Cell and we all had this conversation about nine months ago. The fingertip is one of those areas that actually has been known to regenerate on its own without any intervention, so it isn't an ideal litmust test of efficacy. I think it will be useful as a wound dressing, but I don't think it will necessarily serve our purpose of perfectly regenerating our lost tissue. I read somewhere, back when I was researching this substance heavily, that they were thinking of mixing it in with Restylane to make a much more effective and long lasting filler. That could be helpful... We will see!
If I just looked at that finger tip information and used it as the litmus test then I'd be guarded like you. But looking at other stuff, I'm very optimistic about this treatment, and I think this treatment is exciting for scar treatments. The only thing that might slow it down is a thinking of the scientific community???
Anyway look at these circumstances and nit them together:
Someone I've researched once said something like, 'regeneration goes back to the scar.'And he said later that skin was the easiest tissue to engineer.
Someone can now regenerate a bladder. IMO if they can regenerate a bladder, which is more complex than skin, using an extracelluar matrix there must be knowledge to regenerate skin. Skin then --> later comes the more complex organs.
So skin is an organ and one of the easiest organs to regenerate, and they are even on there way to regenerate a liver and a heart. --> 'Skin has been done.'
Skin is the easiest organ to make, and I think some scientist once said something like, 'that scarring mechanisms are similar around the body, except the liver, mouth ect. Which can regenerate, and treatments that can be used on the skin organ can be used on internal organs.'
Forget the finger tip, this matrix first found out that this matrix regenerated an aorta, when some tubular intestine was put into a dogs heart and the intestine transformed into an aorta with no scarring, it clearly regenerated here and because the scarring mechanism around the body are similar. Clearly here we have proof of concept that the matrix is very powerful at antiscarring, on all organs it stops the enzymes from making the scar wall thus enabling regeneration.
The scientist on the video also claimed our extracelluar matrix is similar to the pig and the dinosaur. Making an argument for what is good for one species is good for another, meaning the matrix can transfer to different species, meaning the pig matrix is universal.
This matrix has been used in the surgical process of internal organs, and they have come out of surgery regenerated
My opinion, is this matrix can work on organs in the body that can't regenerate on their own.
Regarding restalyne, I think with pit scars, what you would have to do is cut out the wall (scar tissue) and plug (perhaps you could have a measure tailored matrix plug?) up the pit with the matrix, like what metal beaters do to car with dints in them, so the skin can regenerate around the scaffold. I don't think you would need the restalyne.
AccutaneGaveMeEczema said,
'If I remember that article on the Acell fingertip said the man had a small scar line where the finger was cut off, even after it regenerated.'
The tiny small scar was nothing compared to the majority of the finger tip which regenerated. It is like antibiotics, when you get them you have to complete the coursea You could put that down to him stopping when he realized his finger tip was regenerated, like he said to himself, 'well my bone tissue seems to have formed, the wound is still open, and I'm not bothered about a 3mm by 3mm scar on my tip, at last I can stop putting on the smelly powder.' That probably has more to do with human apathy to following the course of treatment than the treatment not working. I bet if it was his face or another visible body part he'd have followed the treatment course. Anyway 98% of his finger regenerated.
Someone can now regenerate a bladder. IMO if they can regenerate a bladder, which is more complex than skin, using an extracelluar matrix there must be knowledge to regenerate skin. Skin then --> later comes the more complex organs.
Well, although skin may be theoretically the simplest tissue to regenerate, I think that it is decidedly more complex and delicate regeneration process since it is an external organ.
Of all of the obvious differences between a bladder (or any other organ, for that matter) and facial skin, the one distinction that may be most problematic in regards to regeneration may be the most obvious of them all- skin is VISIBLE. You have two levels of regeneration- a functional regeneration and an aesthetic regeneration. These are not necessarily inextricably linked. Combine this with the fact that "regeneration" for one researcher may differ from that of another. When researchers use the term "regeneration" are they speaking of complete regeneration (functional and perfect cosmetic regeneration) or are they speaking of functional regeneration (a functional finger that still retains a scar). The term "regeneration" is applied to both of these outcomes, yet they differ greatly.
Even though internal organs may be more difficult to regenerate from a standpoint of functionality, you don't necessarily have to conern yourself with any anomalies of a purely aesthetic nature and thus, it's more forgiving in that respect.
With skin, functional and aesthetic regneration need to be complete, and total aesthetic regeneration is what is proving to be obstacle.
Someone can now regenerate a bladder. IMO if they can regenerate a bladder, which is more complex than skin, using an extracelluar matrix there must be knowledge to regenerate skin. Skin then --> later comes the more complex organs.
Well, although skin may be theoretically the simplest tissue to regenerate, I think that it is decidedly more complex and delicate regeneration process since it is an external organ.
Of all of the obvious differences between a bladder (or any other organ, for that matter) and facial skin, the one distinction that may be most problematic in regards to regeneration may be the most obvious of them all- skin is VISIBLE. You have two levels of regeneration- a functional regeneration and an aesthetic regeneration. These are not necessarily inextricably linked. Combine this with the fact that "regeneration" for one researcher may differ from that of another. When researchers use the term "regeneration" are they speaking of complete regeneration (functional and perfect cosmetic regeneration) or are they speaking of functional regeneration (a functional finger that still retains a scar). The term "regeneration" is applied to both of these outcomes, yet they differ greatly.
Even though internal organs may be more difficult to regenerate from a standpoint of functionality, you don't necessarily have to conern yourself with any anomalies of a purely aesthetic nature and thus, it's more forgiving in that respect.
With skin, functional and aesthetic regneration need to be complete, and total aesthetic regeneration is what is proving to be obstacle.
I get what you are saying functional verse aesthetic... I mean it may save a life to put skin on a burns patient, but it won't help his mental health if it doesn't look normal... I see where you are coming from.
But what I was trying to convey was that we know what makes skin form, over forming scarring in a local skin knitting way. They can put together extracelluar matrix and make local tissue instead of scar...
I should have then mentioned the word 'local' in some transitional paragraph...
And my thinking with this matrix is it works with what it is locally surrounded by in,
example:
1. if it is applied to a ligament, the local growth factors on the living organism, on the local ligament are fooled in to thinking it must form the local ligament tissue over a scarring repsone.
2. If it is applied to a 'functional' skin tissue in a dish, the local growth factors on that 'functional' skin will be fooled that it must make a local functional skin over a scarring response.
This means if you have a wond on your arm and you apply the matrix, the skin that grows will be the same type of skin as surrounds it locally.
While the finger tip is one of the most likely spots on the human body to regenerate, I believe that all of our tissues have the capacity to regenerate. Obviously the tip of the finger doesn't regenerate in a majority of patients who lose it. Acell seems to kick start this process....and I am very optimistic because now we can figure out what makes the tip of the finger different than the rest of the body in it's regenerative abilities and what in acell directs it to regenerate. If we can figure these things out than it is VERY possible to reformulate acell in such a way that it works in other sites of the body and not just a spot where regeneration is highly possible. That is being said with the notion that Acell doesn't work in other parts of the body ...but we still don't know about that yet.
As with the scar the guy says he has, an idea that I want to throw out there on that is maybe it is due to the fact that he did not put Acell on the wound immediately after the trauma. I think he had the Acell overnighted? My guess that scar tissue on the perimeter developed while he was waiting for acell, which would have directed it to make regular tissue instead of scar tissue.
I know who started the blog, and haven't heard from him in a while... I'll think he's just very busy with school right now or just waiting for the next revolutionary announcement, just like the rest of us.
just wanna pay a big compliment to anna for her hard discovery work, u're a brain of this disccusion, well done!
i am big fan of a juvista thing, its so inovative and different to all those creams full of colagen peptides and aloe vera giving miraculous and rather sickly promisses on scar healing. i was very very dissapointed when the deal for fast track in US was disallowed by FDA, it probalby was the only hope to get hold of some juvista before it (fingers crossed)hits the market late 2011. dont quite thing skin will heal with NO scars but still doing the excision surgery with or without juvista i am sure make a massive difference. Ideally combinating with Zesteem for a bit of speeding things up, will be great and fairly possible as zesteem is going to be available 2010. this waiting for things to move on physically hurts!!
Thought about making a new thread for this, but I think it is appropriate in here.
I think it's great that Juvista isn't even out yet and people are already patenting alternate ways to inhibit TGF-B. This way seems easy, and very inexpensive. Sodium Bicarbonate to the rescue! plop plop fizz fizz!!!!
here is the patent information
"New and existing scars can be treated, as well as wounds prior to scar formation. The compositions can be used as an aid in the natural healing process, to allow reduction of scar formation, for example, in a wound region.
In one embodiment, a method for reducing scar formation is provided, the method comprising administering hyaluronic acid and an alkalinizing agent, together or in alternation, to the dermis tissue of a wound site, to increase the pH of a wound site, and to induce an alkalinization of the wound site. This can result in inactivation of TGF-I, thereby inhibiting the scar formation on the wound site. The wound site is allowed to heal, thereby reducing scar formation on the healing site."
hmm says that existing scars can be treated ...To what extent? I guess that is just a hypothesis or saying that existing scars CAN BE TREATED but there may be no improvement.
Maybe I should start a alkaseltzer regime a la bruin?
Thought about making a new thread for this, but I think it is appropriate in here.
I think it's great that Juvista isn't even out yet and people are already patenting alternate ways to inhibit TGF-B. This way seems easy, and very inexpensive. Sodium Bicarbonate to the rescue! plop plop fizz fizz!!!!
here is the patent information
"New and existing scars can be treated, as well as wounds prior to scar formation. The compositions can be used as an aid in the natural healing process, to allow reduction of scar formation, for example, in a wound region.
In one embodiment, a method for reducing scar formation is provided, the method comprising administering hyaluronic acid and an alkalinizing agent, together or in alternation, to the dermis tissue of a wound site, to increase the pH of a wound site, and to induce an alkalinization of the wound site. This can result in inactivation of TGF-I, thereby inhibiting the scar formation on the wound site. The wound site is allowed to heal, thereby reducing scar formation on the healing site."
hmm says that existing scars can be treated ...To what extent? I guess that is just a hypothesis or saying that existing scars CAN BE TREATED but there may be no improvement.
Maybe I should start a alkaseltzer regime a la bruin?
try it on ur pet hamster first
I know who started the blog, and haven't heard from him in a while... I'll think he's just very busy with school right now or just waiting for the next revolutionary announcement, just like the rest of us.just wanna pay a big compliment to anna for her hard discovery work, u're a brain of this disccusion, well done!
i am big fan of a juvista thing, its so inovative and different to all those creams full of colagen peptides and aloe vera giving miraculous and rather sickly promisses on scar healing. i was very very dissapointed when the deal for fast track in US was disallowed by FDA, it probalby was the only hope to get hold of some juvista before it (fingers crossed)hits the market late 2011. dont quite thing skin will heal with NO scars but still doing the excision surgery with or without juvista i am sure make a massive difference. Ideally combinating with Zesteem for a bit of speeding things up, will be great and fairly possible as zesteem is going to be available 2010. this waiting for things to move on physically hurts!!
Thank you dafa77! We are all in this together though...hopefully we will have vague memories one day of when we actually had scars...
I really think that we are close to the time where there will no longer be the telltale white lines which serve as evidence of surgical procedures. This will be through Juvista/Juvidex or any of the other myriad of companies now coming out with TGFB1 suppression. I think we are a bit further away from tissue regeneration (When I say tissue regeneration I mean the body reforming lost tissue as it was before injury or disease.) We will see this Summer what the outcome is of the current DARPA study underway where they are working to create a blastema. There will be no telling of what wonders are in front of us if they are able to do that...
Maybe I should start a alkaseltzer regime a la bruin?
Maybe...
I remember a few years back there was a TCA/ EGF cream thread. I tried this treatment and had a little bit of success. In this thread something was brought up that stated that when we scar (indented missing tissue scars) it is due to the epidermis reforming (healing) prior to the dermis. The epidermis is then like a piece of saran wrap over the dermis which serves as a bio-electric resistor and prevents the neurological regenerative signal for traveling to replace the lost tissue. The theory was that the EGF cream would be keep the epidermis from completing it's healing activity prior to the dermis. It was all theory, but it would be interesting to see what naturally occuring substances (aloe for one I believe or maybe alka seltzer? ) could interupt this premature healing action of the epidermis or alternately keep the dermis healing in spite of the healed epidermis.
Whatever became of the interest in Hebermin cream? I know that it was very hard to come by (only available in Cuba, I beleive). Does anyone know if anyone was able to obtain this and experiment with it.
It was supposedly supposed to have an amazing regenerative effect.
Interesting thread:
Anna, How bad is your scarring?
I personally have many scars on my forehead and both cheeks and I have to say that TCA has worked very, very well for me. I just did a cross about 2 weeks ago and some of my scars have actually closed up and all of them have decreased in width and depth... I haven't used anything else since then, except Retin A, and also, TCA Latte for a peel. I'm very pleased with the results, overall.
Jan31
Yes, we got some. That's what I used with the TCA. I also tried TCA with ReVive...not too much success. Sadly! There was one gal Reilly I believe who had great success. I don't think she used Hebermin though.
Hi January 31st-
I am so happy to hear that you've had success with your treatment choices!
I have an eclectic collection of scars, some of which have been treated quite successfully with spot dermabrasions and subcisions and fillers, and recently the ACV. The ones that continue to bother me are the icepicks on my nose. I have tried TCA CROSS with 100% TCA (with some success) on those but they are still there. They frustrate me...hence my never ending quest... I should start using Retin-A again.
I don't know what the next treatment path will be.
Thanks, Anna
Anna, How bad is your scarring?
I personally have many scars on my forehead and both cheeks and I have to say that TCA has worked very, very well for me. I just did a cross about 2 weeks ago and some of my scars have actually closed up and all of them have decreased in width and depth... I haven't used anything else since then, except Retin A, and also, TCA Latte for a peel. I'm very pleased with the results, overall.
Jan31
Hi Jan31,
Did you perform the TCA yourself or get it done in a clinic?
What % was the tca and did you get the full face done or just scarred areas?
Thank u