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Lamarr,
I was doing some reading up on Hydroxychloroquine and it seems to be quite safe, most articles saying that doses kept around 200mg per day have literally no chance of eye toxicity and that the risks are only in those who use high doses (400mg-600mg per day) but even at those doses, it is still farily rare.
I think I remember you saying your mother or someone in your family has been using this medication correct? What have their side effects been?
Also, do you feel this medication would work as well as Mepacrine, they are both suppose to work in very similar ways. The only bonus being there is no yellowing with the Plaquenil. Did Dr. Chu ever get into why he prefers Mepacrine over Plaquenil?
Thanks for the input.
Yo
Saddens me to see the same guys having problems still. Truely hope things have a got a bit better at least?
The flushing has reduced I'd say about 80%. I do have to drink A LOT of water though to keep it down. I get it only on the tube now (London subway) where it's ridiculously hot but I of course go a lot more red than the average!
I've got a few spots back but that's a fair price to pay for severe reduction in the flushing. They're on my forehead which I believe is more related to my bowel problems anyhow (too much information?! Most probably).
Alcohol is also an inducer for the old flushes but with my IBS I find it hard to drink a lot anyhow.
Oh also with regards to heat, I've been going to the Middle East a lot (I'm half Israeli) and no flushes! Even in the ridiculous midday heat.
So there IS hope. For anyone reading this who's on tane and is starting to get flushes PLEASE STOP taking and go see your derm. I put my foot down and told him I was coming off it even though he disagreed.
Good luck to yall
safe x
I'm glad to hear that you are recovering. My level of flushing has remained constant for a year i'd say. With regards to you getting some acne back if you wanted to try a topical I would recommend klaron (sulfur sulfacetamide) lotion. It is really gentle and doesn't aggravate the flushing, but seems to be quite effective on dry post tane skin.
Hey Lamarr,
what doses of Clonidine and Propranolol were you on when you started the Mepacrine? Also, how long after being on the Mepacrine did you stop these? Did you stop them gradually? or at the same time?
I know you still use them for acute situations when you are going out clubbing etc. but I am curious as to the details on your doses and scheduling for stopping them when being on Mepacrine.
I am currently on Propranolol, about 20-30mg daily along with the Mirtazinpine.
Feel free to PM me or drop me a line here.
Cheers,
75mcg of clonidine 3-4 times daily, 20mg of propranolol 3-4 times daily... I think this is part of the reason why i saw results in my flushing so quickly, once the inflammation was removed i had the helping handd of several anti flushing meds. I stopped then after about 6 months? i'm not sure though, i stopped them fairly gradually yeah, don't need to worry to much though just don't do it suddenly.
Lamarr,
I was doing some reading up on Hydroxychloroquine and it seems to be quite safe, most articles saying that doses kept around 200mg per day have literally no chance of eye toxicity and that the risks are only in those who use high doses (400mg-600mg per day) but even at those doses, it is still farily rare.
I think I remember you saying your mother or someone in your family has been using this medication correct? What have their side effects been?
Also, do you feel this medication would work as well as Mepacrine, they are both suppose to work in very similar ways. The only bonus being there is no yellowing with the Plaquenil. Did Dr. Chu ever get into why he prefers Mepacrine over Plaquenil?
Thanks for the input.
Yeah i have said the same to people over on the rosacea froum but soon as they see it as a possible side effect.... My mum takes 400mg for reactive arthritis on my recommendation and it has worked very well for her. I think chu likes the fact he doesn't need to arrange eye check ups just to be sure. I personally feel they will work just as well as each other for the rosacea/flushing.
My mum has just had some upset stomach, but i also have/had this from mepacrin i just don't count it as a side effect because it is to be expected to some degree and does ease up as time goes on for sure.
hey guys... so i think this is the best area to try and get some answers....
i went on mino from Nov-april with great results at first actually but the acne started to come back around march...
So now i am on accutane. My face is VERY red. It goes from both cheeks and nose. For the guys out there or people who know what a chinstrap beard is, it looks like i have a chinstrap beard on my jaw because its white but everything above it is bright red.
Any help for this?
When you guys are refering to minocycline and accutane flushing.. is that for those who took accutane first then minocycline? or other way around?
I am actually VERY concerned about this
hey guys... so i think this is the best area to try and get some answers....
i went on mino from Nov-april with great results at first actually but the acne started to come back around march...
So now i am on accutane. My face is VERY red. It goes from both cheeks and nose. For the guys out there or people who know what a chinstrap beard is, it looks like i have a chinstrap beard on my jaw because its white but everything above it is bright red.
Any help for this?
When you guys are refering to minocycline and accutane flushing.. is that for those who took accutane first then minocycline? or other way around?
I am actually VERY concerned about this
Minocycline, in itself, is generally not strong enough to cause problems. I referenced minocycline only because it was making my flushing worse post accutane. Your problem is definitely accutane related. As Peter asked I would be interested in knowing if you flushed as well. How long have you been on accutane and what dose are you taking? If you do not have any flushing along with the redness than there is a good chance it will go away post accutane, but it is far from guaranteed.
Seattle JT you probably were one of the unlucky ppl who got rare side-effects from accutane. Several ppl get irritated/red in their faces and experience some blushing. Im sorry for you, but you really dont have to scare ppl. Since Accutane reduces the natural produced oil in your body, redness quite normal.
And what is seb dermatitits?
Seattle JT you probably were one of the unlucky ppl who got rare side-effects from accutane. Several ppl get irritated/red in their faces and experience some blushing. Im sorry for you, but you really dont have to scare ppl. Since Accutane reduces the natural produced oil in your body, redness quite normal.
And what is seb dermatitits?
Haha are you serious? How exactly am I scaring people?
Seattle JT you probably were one of the unlucky ppl who got rare side-effects from accutane. Several ppl get irritated/red in their faces and experience some blushing. Im sorry for you, but you really dont have to scare ppl. Since Accutane reduces the natural produced oil in your body, redness quite normal.
And what is seb dermatitits?
dude, he isn't scaring anyone he is simply warning the guy who said he is concerned about his redness. I would say the same thing, if anyone is flushing on Accutane and you had no flushing prior to taking Accutane, then you are rolling the dice and could end up with a big debilitating problem in the end.
This thread is almost 40 pages and there have been about a dozen people who have posted post Accutane flushing issues and there at least a dozen more that I know of on a rosacea forum.
If you are going to start debating the frequency of this side effect and making accusations then why bother posting in the thread. This thread is about the poeple who have suffered post accutane flushing and other issues. Although it is not common, there are numerous people with this problem. If someone comes in that is concerened about thier flushing and redness on Accutane, clearly we are going to caution them based on our and others experiences.
Hey! didnt mean to upset you 
Gues im posting it cause im struggeling with the same issue, and gets quite scared bye reading these posts... I did neither experience any blushing before starting accutane, but now(ive taken 376 out of 500 pills), im both having redness in my face and blushes sometimes. This is however mostly an issue in warm places.
Have an appointment with my dermatologist at friday, so hopefully she can calm me down...
1month: 40mg/day
2month: 60mg/day
3month: 60mg/day
4month: 60mg/day
4,5month: 60mg/day
5month: 40mg/day
Concidering my weight, 176 lbs, im not on a high dose.
You guys probably have read tons about this. Does this often go away after finishing accutane? Ive read both, but many ppl are worried after like 2-3 months. As i understand, it can take up to a year before your skintone is back to normal.
And what is seb dermatitits?
Since no one answered the question, I did some googling (internet searching...lol).
Here are some links about Seboricc Dermatitis, I also did a google search for Seb Derm. in Norwegian, since it be easier for you to understand. I'm not that great in Norwegian, so I didn't check the sites 
http://familydoctor.org/online/famdocen/ho...orders/157.html
Hey! didnt mean to upset you
Gues im posting it cause im struggeling with the same issue, and gets quite scared bye reading these posts... I did neither experience any blushing before starting accutane, but now(ive taken 376 out of 500 pills), im both having redness in my face and blushes sometimes. This is however mostly an issue in warm places.
Have an appointment with my dermatologist at friday, so hopefully she can calm me down...
1month: 40mg/day
2month: 60mg/day
3month: 60mg/day
4month: 60mg/day
4,5month: 60mg/day
5month: 40mg/day
Concidering my weight, 176 lbs, im not on a high dose.
You guys probably have read tons about this. Does this often go away after finishing accutane? Ive read both, but many ppl are worried after like 2-3 months. As i understand, it can take up to a year before your skintone is back to normal.
Its all good man. As far as I know none of us that post on this thread were on too high of a dose either. Obviously the higher the dose the greater the chance of side effects, but even at 40 mg a day accutane can cause problems. As I said above many people find that their redness goes away post accutane, but if you flush its a whole different ballgame (not sure from your description if you flush or not?). I guess it depends on what your definition of blushing is. If you are merely experiencing short bursts of redness due to embarrassment then I would say that you were fine. But if you are flushing for extended periods of time then you are at a higher risk of maintaining the redness. It is said that accutane can stay in your skin for a year, but if you get side effects that linger they are probably due to the fact that accutane alters your immune system so they would not clear up just because accutane is out of your system.
Also, I don't know how much research you have done into this, but some of us did not experience the flushing until we were nearing the end or after ending accutane. Based on all that I know I wouldn't say that it was uncommon for people to get side effects post accutane. I am not trying to scare you, but if you were unaware that these things were a realistic possibility then I would say you are much better off knowing the full risks. When I started to flush post accutane I had no idea that it could happen and not knowing made it much worse when it actually happened.
I do not know your dermatologist and therefore cannot say whether or not they have experience with post accutane side effects. But from what I do know the majority of dermatologists do not have much experience with post accutane side effects and are therefore not good sources of information regarding them. You would be surprised by how many dermatologists say that peoples side effects are not related to accutane when all signs clearly point to it being the cause.
Hey! didnt mean to upset you
Gues im posting it cause im struggeling with the same issue, and gets quite scared bye reading these posts... I did neither experience any blushing before starting accutane, but now(ive taken 376 out of 500 pills), im both having redness in my face and blushes sometimes. This is however mostly an issue in warm places.
Have an appointment with my dermatologist at friday, so hopefully she can calm me down...
1month: 40mg/day
2month: 60mg/day
3month: 60mg/day
4month: 60mg/day
4,5month: 60mg/day
5month: 40mg/day
Concidering my weight, 176 lbs, im not on a high dose.
You guys probably have read tons about this. Does this often go away after finishing accutane? Ive read both, but many ppl are worried after like 2-3 months. As i understand, it can take up to a year before your skintone is back to normal.
No worries bro, it's all good. Just didn't want to turn this into a battle of wits between Accutane supporters and people who have been screwed by it...there are enough of those threads already. 
I had no flushing prior and strated same as you are now with blushes in warm rooms at around month 5. My derm assured me that it is transient and would stop once I finished my course which was 2 more months. I was also on a low dose, never went above 40mg/day. About a month prior to finishing my come and go flushing turned into intense flushes to everything. I was flushing literally 24/7 and forced to sit in front of a fan. My derm again said it would go away but could take up to 6 months. I stopped the medication as soon as this sudden onset took place. The flushing has never resolved. Although better a year and a half later but I am on several meds to combat the flushing so not sure if it is the meds, time or likely a combination but it is still a very big problem.
All I can say is be aware that you are taking a gamble if you are flushing now on Accutane and never have prior to taking it. It could go away a few weeks or months after your course or you could end up like many of us here with a big problem. I know if I could go back I would have stopped when I first started having those transient blushes to warm rooms at month 5. But there is no point in if's and but's for us....but for you it is something to seriously consider.
Good luck and I hope things work out for you.
Ok, thx for good answer:) I`ve also noticed, by reading posts on the internet, that there are lots of really lousy dermatologists. Sure there are a risk of getting side-effects, but it must be kinda bitter to get side-effects b/c your derm buts you on a way to high dose.
"I guess it depends on what your definition of blushing is. If you are merely experiencing short bursts of redness due to embarrassment then I would say that you were fine. But if you are flushing for extended periods of time then you are at a higher risk of maintaining the rednes"
Well im probably blushing due to embassasment. Its kinda; im going in a rom, in which it might be hot, and just felles the redness arrive. Then I think like; Oh no, plz dont blush, an then im blushing like hell. BUT its only for a very short periode of time. If I "make some wind" with a paper infront of mye face, well it might be gone after max.15-20seconds. Im aslo getting redness in my face if im working out and stuff, but guess thats quite normal.
So am I experiencing the right kind of blushing?
And thx Raimundo, now im a wiser man
soul78: Ahh, I understand you sadly got the blushes a bit futher. So my conclusion might be wrong, but I think, by reading both here and on other forums, that flushin/blushing is quite normal, and that only a few really unlucky ppl gets it like you 
My point in the first post was just that there are sadly only ppl who struggle with the side-effects post accutane that writes about it. The ones who get fine, never bothers.
But what kind of blushing are you talking about? Mine comes maybe a couple of times a day, and last, like I mentioned, a few seconds. Otherwise im only having a red face, but this seems to be normal? Are you blushing like when you are alone in a room, or does it also come as a result of embarrasment?
Ok, thx for good answer:) I`ve also noticed, by reading posts on the internet, that there are lots of really lousy dermatologists. Sure there are a risk of getting side-effects, but it must be kinda bitter to get side-effects b/c your derm buts you on a way to high dose.
"I guess it depends on what your definition of blushing is. If you are merely experiencing short bursts of redness due to embarrassment then I would say that you were fine. But if you are flushing for extended periods of time then you are at a higher risk of maintaining the rednes"
Well im probably blushing due to embassasment. Its kinda; im going in a rom, in which it might be hot, and just felles the redness arrive. Then I think like; Oh no, plz dont blush, an then im blushing like hell. BUT its only for a very short periode of time. If I "make some wind" with a paper infront of mye face, well it might be gone after max.15-20seconds. Im aslo getting redness in my face if im working out and stuff, but guess thats quite normal.
So am I experiencing the right kind of blushing?
And thx Raimundo, now im a wiser man
soul78: Ahh, I understand you sadly got the blushes a bit futher. So my conclusion might be wrong, but I think, by reading both here and on other forums, that flushin/blushing is quite normal, and that only a few really unlucky ppl gets it like you
My point in the first post was just that there are sadly only ppl who struggle with the side-effects post accutane that writes about it. The ones who get fine, never bothers.
But what kind of blushing are you talking about? Mine comes maybe a couple of times a day, and last, like I mentioned, a few seconds. Otherwise im only having a red face, but this seems to be normal? Are you blushing like when you are alone in a room, or does it also come as a result of embarrasment?
No dude, flushing and blushing on accutane is not normal and a lot of those who get this (like me and the other dozen or so posters in this thread) end up with it becoming intense and permanent. Redness is normal NOT flushing.
From what you describe I would say you are starting to flush. Several times a day, the feeling of it coming on and trying to fight it off mentally and then having to fan your face with paper is not what I woud call blushing, there is heat associated with it, so it is flushing.
Not much more we can say, you are describing what we all started out with (minor trasnsient flushes) and then ended up with a permanent flushing problem.
I would say you are at a stage where I would seriously consider stopping. It's a roll of the dice and a big gamble in my opnion. I was told by my derm that it was normal and would go away, but it never did.
I don't know, it could remain transient and minor and go away after your course OR it could turn intense at the blink of an eye and stay permanent after your course.
Not trying to scare you, just giving you the facts on how it is and how it could play out. Ultimately it is up to you as it is your body.
Fuck!!!!! Not what I wanted to hear. Well, derm in like 9houers, dont know what the fuck to expect
Like I said, not trying to scare you or stress you out but just giving you facts as we see them. At the very least, I would consider reducing your dose over the next few weeks to see if these flushes upi are getting let up in frequency and intensity and if they do not, perhaps stop.
As the others have said, derms are pretty limited when it comes to Accutane side effects and will likely pass it off as something that will go away once you stop, which it very well could but it also very well couldn't.
Just take some time after you talk to your derm and weigh the pros and cons.
I hope everything works out for you.
Well went to the derm and she didnt seem worried at all. I couldnt really relaxe with her answer and told her to get the "superior-derm". It was a old lady who had lots of experience with accutane. She didnt seem worried either, and recommended me to finish the cource as planed. Their explanation was that my skin is much thinner and therefore the blood-vains are more visible. To me, this seems natural. I have sent in an question to another derm, and are waiting for his reply.
Unless he recommends me to do otherwise im going to maintain a 40mg/day cure. I was originally on a 60mg/day cure, so it might make it a bit better.
It looks like we might got some of the same, and this worries me, but there is no doubt that you have it much harder than me. And yeah it might develop in that direction to me asvel, but until im noticing this, im continuing and praying it will go well.
Well went to the derm and she didnt seem worried at all. I couldnt really relaxe with her answer and told her to get the "superior-derm". It was a old lady who had lots of experience with accutane. She didnt seem worried either, and recommended me to finish the cource as planed. Their explanation was that my skin is much thinner and therefore the blood-vains are more visible. To me, this seems natural. I have sent in an question to another derm, and are waiting for his reply.
Unless he recommends me to do otherwise im going to maintain a 40mg/day cure. I was originally on a 60mg/day cure, so it might make it a bit better.
It looks like we might got some of the same, and this worries me, but there is no doubt that you have it much harder than me. And yeah it might develop in that direction to me asvel, but until im noticing this, im continuing and praying it will go well.
As I told you before most derms do not have experience with post accutane side effects so you really have to take it upon yourself. It is fine if you go forward with your treatment, but be sure to understand that if you were to start getting the flushing badly there is no guarantee that it would subside even if you immediately stopped taking accutane. As soul said flushing and blushing are completely different. Blushing only lasts for a couple of seconds whereas flushing is a constant state of burning/redness for hours...
As I told you before most derms do not have experience with post accutane side effects so you really have to take it upon yourself. It is fine if you go forward with your treatment, but be sure to understand that if you were to start getting the flushing badly there is no guarantee that it would subside even if you immediately stopped taking accutane. As soul said flushing and blushing are completely different. Blushing only lasts for a couple of seconds whereas flushing is a constant state of burning/redness for hours...
Well, i have a little constant redness, which is normal. Then some days i do get some incidents of blushing, BUT this only last for a couple of seconds, and the blushing-redness goes away in a mather of seconds after that. I have almost nevner blushed before. It really is a difference, and to me it seems like i do got the light version, and cant by any means relate to a flushing that burns, or stays red for hours.
Well went to the derm and she didnt seem worried at all. I couldnt really relaxe with her answer and told her to get the "superior-derm". It was a old lady who had lots of experience with accutane. She didnt seem worried either, and recommended me to finish the cource as planed. Their explanation was that my skin is much thinner and therefore the blood-vains are more visible. To me, this seems natural. I have sent in an question to another derm, and are waiting for his reply.
Unless he recommends me to do otherwise im going to maintain a 40mg/day cure. I was originally on a 60mg/day cure, so it might make it a bit better.
It looks like we might got some of the same, and this worries me, but there is no doubt that you have it much harder than me. And yeah it might develop in that direction to me asvel, but until im noticing this, im continuing and praying it will go well.
As we said, no derm is going to recognize flushing as a potential problem unless you are seeing Dr. Chu or someone who is versed in post Accutane flushing issues. IF there is heat associated with your blushing as you said you need to fan you face with a paper etc. I would take that as a big red flag personally because as far as I know, blushes do not have heat associated with them but flushes do.
Just be aware of the risks and that I was also on 40mg per day and had mild transient flushes that were brief and was also told it would go away and at the blink of an eye it turned intense and did not let up even when I stopped within a couple days of it happeneing.
The odds are in your favour that it will likely not get as bad as ours as I do believe we are in the lower percentile of side effects, but continuing with your course could pose a risk if you are experiencing heat associated flushing and are only half way through. I respect your decision...I really hope things do not take a turn for the worst but if I could go back in time and be at the point again where you are at I would stop (obviously) or at the very least cut my dose in half.
A few more similar accounts I came across the other day you may want to read over;
http://www.rosaceagroup.org/The_Rosacea_Fo...934&page=19
http://www.rosaceagroup.org/The_Rosacea_Fo...8890&page=2
You have informed yourself of the risks so just be sure you are 100% comfortable with your decision and best of luck and I hope things work out!
Thx for the fast and informative post guys. I appriciate it, I truly do.
I am almost done with month 5, and will try to continue approximately one and a half month futher. Sadly none of us can look into the future, and therefore we must do what we belive is the right thing.
I will not be posting updates on this forum, thus this posts make me to worried. I will however come back after ending the curse and either be one hell of a happy man, or joining your club.
Thanks for trying to help me, and may we all get rid of our skin problems sometime in the future.