After trying several anti-acne treatments with no results, in July 2015 I started taking spironolactone (50 mg slowly increaslng the dose to 100 mg); after 2 months I stopped having period at all. As I assumed it was a result of inhibiting my hormones, I continued taking same dose till April 2017 (-my skin condition changed a lot, it was a huge relief..). I decided to taper off Spironolactone April this year, because I was worried about my health and fertility. After 2 months on 50 mg of Spiro I finally got my period (I also checked levels of my hormones and they were still very low). Since then (June 2017) I was menstruating once per 2 weeks, unfortunately I started breaking out as well..3 weeks ago I decided to increase my dose to 87,5mg. I know it may have been irresponsible, but having acne was so overwhelming I decided to pay any price to keep it away I feel trapped and hopeless, I do not want to harm myself but also don't know what to do- Spiro helped my skin so much like nothing did. I wonder if inhibiting hormones for a longer time can cause permanent demage? Or they will unblock when coming off medicine anytime? I was thinking about taking Spiro till planning to get pregnant, but of course I would not like to risk. Any help appreciated!