So I've started on my isotretinoin journey about three months ago. I've been taking 40mg a day with Claravis. I'm a female about 111 pounds and 5'2". So far I have one pimple! I have minor chapped lips and that's pretty much it. No other side effects and my skin is basically almost cleared up. I use cetaphil gentle wash, bio oil serum as my mosterizer for day and night and Burt's bees Chapstick. I take my pill at night after dinner which is when my meal has the most fat, I meal prep so my diet is only lean meats. I workout 4 times a week minimum and I drink lots of water. I can't express how important that is, I can gurantee you that you aren't drinking enough. Your liver needs the water and healthy food. So hopefully this would help anyone starting or currently on it. It does not have to be the worst 5-6 months of your life!