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Every female thinking about going on Accutane should consider its potential to reduce the odds of future conception:
H. Aksoy, L. Cinar, G. Acmaz, U. Aksoy, T. Aydin, U. E. Vurdem, L. Oz, O. Idem Karadag, and D. Kartal, The Effect of Isotretinoin on Ovarian Reserve Based on Hormonal Parameters, Ovarian Volume, and Antral Follicle Count in Women with Acne, Gynecol Obstet Invest, vol. 79, no. 2, pp. 7882, 2015.
Conclusion: Our study is the first to analyze the levels of serum AMH, AFC, and OV together in patients treated with oral isotretinoin for acne. The results of our study demonstrated that oral isotretinoin had a significant negative effect on ovarian reserve.