I am beginning a 20mg/week microdose of accutane, I have seen forums where people take one 20mg pill once a week and others take a 10mg pill twice per week, and examples where some people take 40mg once a week and others take a 20mg pill twice per week... does anyone know if there is a difference when taking a certain amount of accutane once a week as opposed to achieving the same weekly amount by taking smaller pills less often? when i tried 10mg twice a week (20mg weekly), i noticed a tiny bit of dryness in the first 2 weeks. that was a while ago, and now i am roughly the same number of days into a slightly different regimen of taking ONE 20mg pill per week (same amount) yet i do not see any dryness this time... maybe its because my washing regimen has changed between then and now as well... anyway, worrying that is is less potent this way?? opinions/knowledge welcome! thanks !!