Hello everyone,

After my current prescription has completely failed to make any difference on my complexion, I want to try something new, however I am very hesitant about trying accutane as I'm not sure how well my body will handle it. I am hoping your expertise can guide me to a solution other than isotretinoin, if one exists.

Things I have tried over the years:

Stievamycin - not much effect if memory serves

Benzoyl Peroxide - my skin has a terrible reaction to this medication, even in low doses

Salicylic Acid - have used this in many many forms. little effect

Minocycline - it worked excellently, but I stopped taking it after a number of months because it is unhealthy to take antibiotics indefinitely. Acne reappeared after a couple months without the medication. I haven't taken it since because of some of the side effects that have been reported, plus I don't think it will work a second time. Instead I tried:

Tetracycline - no effect

Doxycycline[most recent] - no effect, I thought it was slowly working until this week when my skin got worse than before I started.

Just some background information: I have had acne with varying severity for coming up to four years. My acne is currently moderate or moderate-severe, but not cystic. I'm looking for a recommendation from someone with a similar experience, who did not respond to the above medications but did to something else. Thank you.