Best to just ask your doctor to up your dosage. Pharmacies time your refills to prevent drug abuse. If you take 3x a day you will need to refill early and the pharmacy won't allow it.

50mg was a drop in the bucket for me...did nothing. 100mg was much better.

Thank you for the comment. My doctor did prescribe 25 mg 3x/day, so I have enough for that. I've been quite sensitive to the side effects of Spiro and have had a hard time taking more than 50 mg. I wasn't sure if anyone had success with taking a low dose three times a day instead, or if it would be best to take 25mg in the am and 50 mg in the pm.

Thank you for the comment. My doctor did prescribe 25 mg 3x/day, so I have enough for that. I've been quite sensitive to the side effects of Spiro and have had a hard time taking more than 50 mg. I wasn't sure if anyone had success with taking a low dose three times a day instead, or if it would be best to take 25mg in the am and 50 mg in the pm.

Oh, well, go for the 3x a day then. Generally the smaller the dose at one time the easier it is for your body to handle.

Hi I have been on 25 mg/day for one week now. My Rx is for 50 mg/day, but I don't want to shock my system, so each day I have been splitting a 25 mg pills in half, and taking one half in the AM and one half in the PM. So far so good, minor whitehead right now, otherwise all clear at the moment, but I am in the middle of my cycle when I am usually clear, so I doubt it has to do with the spiro. Tonight I increased my dosage to 3/4 of a 25 mg pill, twice a day. So that amounts to 37.5 mg per day. I plan to try this for at least a week.