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Repairing the long-term damage from Accutane

 
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57
(@doctorcolumbus)

Posted : 06/27/2020 3:02 pm

4 hours ago, Lio98 said:

Has anyone found a way to increase dihydrotestosterone? Got it checked last week and it's in the basement. So mean if someone has found something that has really increased its value, not just a guess what might help, I have tried a lot.

And nobody really knows if Accutaneis also serotonin reuptake inhibiting??

Can you post the full report?

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2
(@lio-k)

Posted : 06/28/2020 10:49 am

@DoctorcolumbusNot possible, have no report on it. Have it done at my own expense, norm range 219-1141 and I have 276.

The source of the serotonin thesis is in my last post above

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1753
(@truejustice)

Posted : 06/28/2020 9:16 pm

10 hours ago, Lio98 said:

@DoctorcolumbusNot possible, have no report on it. Have it done at my own expense, norm range 219-1141 and I have 276.

The source of the serotonin thesis is in my last post above

Are you going to work with someone to try and resolve?

If so who, which field?

Best of luck, hope you find a solution!!

I didnt know you could test serotonin like that

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(@isojim)

Posted : 06/29/2020 7:24 am

anybody want try dr pezzi method?

using finasteride to recover post accutane syndrome.

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12
(@arus9000)

Posted : 06/29/2020 9:40 am

2 hours ago, isojim said:

anybody want try dr pezzi method?

using finasteride to recover post accutane syndrome.

I took finasteride after accutane, as accutane made my hair worse. Gave me ED issues and stopped soon after (and the issues went away).
Dont think it helped in any sort of way for other symptoms. But thats just me...

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2
(@isojim)

Posted : 06/29/2020 11:25 am

1 hour ago, arus9000 said:

I took finasteride after accutane, as accutane made my hair worse. Gave me ED issues and stopped soon after (and the issues went away).
Dont think it helped in any sort of way for other symptoms. But thats just me...

i have zero libido and ED right now

it depends onhow you use it. i am say taking finasteride just a couple of days and then stop cold turkey. but i dont know about dosage.

you didnt get ED from accutane so we are not in a same position i think.

i dont know why this topic lasts more than 700 pages and onlyfew people tested finasteride. we have nothing worsethan no libido unless death.

i will use finastride soon and if it doesnt work try Ella. it is risky i know.

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1753
(@truejustice)

Posted : 06/29/2020 5:38 pm

Not interested in working with someone to get out ofthis??

Dont know of anyone getting out of this by self diagnosing and justworking on their own

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Pido, Pido and Pido reacted
MemberMember
397
(@calcified)

Posted : 06/29/2020 11:05 pm

13 hours ago, arus9000 said:

I took finasteride after accutane, as accutane made my hair worse. Gave me ED issues and stopped soon after (and the issues went away).
Dont think it helped in any sort of way for other symptoms. But thats just me...

I had a similar experience with finasteride after Accutane.

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(@isojim)

Posted : 06/30/2020 5:35 pm

anybody experience temporal hair loss on accutane? it is important ifyou experienced it. me? yes

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(@isojim)

Posted : 07/01/2020 6:39 am

On 6/30/2020 at 8:35 AM, Calcified said:

I had a similar experience with finasteride after Accutane.

could you please tell about dosage and days of finasteride usage?

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397
(@calcified)

Posted : 07/01/2020 8:56 am

1 hour ago, isojim said:

could you please tell about dosage and days of finasteride usage?

Didn't help hair loss after Accutane, I took standard dose for at least a year but it didn't stop my hairloss so I gave up on it, but my father is bald.

One thing I will point out finestride users complain ofgyno and Accutane has the same complaints, so how is finestride the cure?

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165
(@under_tow)

Posted : 07/01/2020 10:32 am

1 hour ago, Calcified said:

Didn't help hair loss after Accutane, I took standard dose for at least a year but it didn't stop my hairloss so I gave up on it, but my father is bald.

One thing I will point out finestride users complain ofgyno and Accutane has the same complaints, so how is finestride the cure?

FIN will only make things worse from what I have read of those that tried it to oppose TANE. FIN will lock in the vitamin A.

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2
(@isojim)

Posted : 07/01/2020 11:01 am

2 hours ago, Calcified said:

Didn't help hair loss after Accutane, I took standard dose for at least a year but it didn't stop my hairloss so I gave up on it, but my father is bald.

One thing I will point out finestride users complain ofgyno and Accutane has the same complaints, so how is finestride the cure?

i think finasteride is not direct cure. body replace finasteride and after short period of time we stop using it and body can deal with it and resenthesize receptors much better.

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397
(@calcified)

Posted : 07/01/2020 12:12 pm

1 hour ago, isojim said:

i think finasteride is not direct cure. body replace finasteride and after short period of time we stop using it and body can deal with it and resenthesize receptors much better.

Maybe, but it may be a temporary improvement so to speak let us know how you go, if it doesn't work, feedback still would be interesting.

Not just fin does this, some meds that alter hormones like pain killersI have found blunts libido but when you stop it comes back stronger for short time. Receptors might get more sensitive, but things may go south eventually.

Unfortunately people have said cure is fasting/starving for rest of life, Soulja boy music, go gluten free, risky finestride, anti A, that's why I think it's 700+ pages. Nothing works for everyone.

@under_tow I always wondered if finestride effects vitamin A more than is known.

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(@isojim)

Posted : 07/02/2020 6:00 am

agree. we are not 100%same but everybody should find specific cure that fit the situation.

i fix my sexual dysfunction by marijuana temporary. marijuana is 5 alpha reductase inhibitor and proves finasteridd hypothesisfor curing post accutane syndrome. nobody know about longterm situation.

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(@isojim)

Posted : 07/02/2020 8:13 am

On 1/2/2016 at 4:56 AM, tryingtohelp2014 said:

 

its funny how theres a grain of truth in everything people reported thathelps....but nobody knew why. basically anything that increases UGT2B7,binds accutane metabolitesonce in the bloodstream.

 

ethanol+weed = super glucuronidination

Involvement of UDP-glucuronosyltransferases UGT1A9 and UGT2B7 in ethanol glucuronidation, and interactions with common drugs of abuse.

http://www.ncbi.nlm.nih.gov/pubmed/23230132

finally i found a relationship between weed healing pas and science.

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(@saffronaide)

Posted : 07/02/2020 5:19 pm

On 6/14/2020 at 5:16 AM, Anna Nim said:

I have read every testimony of men who have taken HRT after Finn & Accutane on that site. Overall, it seems that it does not help much. (Depressing As Fuck). It might even fry the rest of the receptors and you may end up with less T after all that. I would expect that it is not so simple as Prostate Inflammation, although I do think many of sufferers have inflammation in many parts of their bodies. 

Do you think that ''fried'' receptors are tissue fixated or is it about the whole endocrine system? I took Accutane for few days when i was just turned out 16. And since that day im concerned about if it did damage my height and facial development or not. Any chance anyone?

On 6/23/2020 at 8:16 PM, IhateAccutane said:

Do you have sometime the same pain after ejaculation, a little pain like a pin or needle. Right in the lower abdominal area, inside.

*it is not me in the photo

Clipboard02.jpg

Jesus. I don't but what is interesting is that, when i got worse with many androgenic supplements two years ago. I had a pressure feeling on this area for a few days! Then it is gone and my baseline got lowered a bit more.

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1753
(@truejustice)

Posted : 07/02/2020 8:22 pm

I personally think, well actually its been confirmed by kinesiologist, its not brain damage per say buy Inflammation. Systemic inflammation is at play still

He cant get to work on it though till lymphatic system works properly so spent last few weeks working on that helping it toclear things

Given no one seems to want to work with anyone, I guess youll have to continue self diagnosing with whatever issue you have ....good luck!!

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19
(@anna-nim)

Posted : 07/04/2020 2:34 am

On 7/2/2020 at 5:19 PM, SaffronAide said:

Do you think that ''fried'' receptors are tissue fixated or is it about the whole endocrine system? I took Accutane for few days when i was just turned out 16. And since that day im concerned about if it did damage my height and facial development or not. Any chance anyone?

Jesus. I don't but what is interesting is that, when i got worse with many androgenic supplements two years ago. I had a pressure feeling on this area for a few days! Then it is gone and my baseline got lowered a bit more.

You took Accutane for a few DAYS and you are worried about damage to your height? and facial development? Unlikely, also if that is all you theoretically have concerns over, I'd be thrilled if I was you. Now, if you later took Propecia or Finn, then it seems to only get worse. I think the more people take the worse it is. It matters not what the damage is, as in a way there is no way to fix it. :(

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716
(@thomas76)

Posted : 07/05/2020 12:37 pm

On 6/18/2020 at 4:49 AM, Lio98 said:

Quote from  RxISK: "Isotretinoin (Accutane) which is used as a treatment for acne [4, 27], and is also serotonin reuptake inhibiting."- Is that really the case?
Source: https://rxisk.org/post-ssri-sexual-dysfunction-pssd/
And is Accutane really a 5±-reductase inhibitor, too?
I ask because I have a special form of erectile dysfunction (soft glans) which psychologically make me the worst. But it seems to be very rare with Accutane. A little more common with SRI and finasteride.
I thought maybe I could improve it with the vitamin A diet, but now I believe that more defects / damage in the brain is responsible for that.
Symptom         SRIs (%)      Isotretinoin (%)        5±-RIs (%) 
Erectile dysfunction 147 (86.0)          46 (93.9)               23 (92.0) 
Loss of libido         135 (78.9)     35 (71.4)              23 (92.0) 
(....)
Soft glans           4 (2.3)               1 (2.0)                0
Source:     https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004900/   
 So I'm thinking about what the right approach would be. With detoxification, liver / bile flushing and cleansing, I don't think it will do much for the long-term sexual side effects.
I am also considering whether myalgic encephalomyelitis + Accutane = SRI triggered long-term side effects of soft glans in my case, because this side effect is so rarely.
I am just so desperate and don't want to believe that it is irreparable damage because then I know I could never have normal sex with it again. Even if I have overcome the illness ME someday. 
So my question is, what exactly in Accutane is similar to the SRI, so that you can find out what the damage may be. If it were "only" extreme vitamin A poisoning alone, then you would at least have a clear starting point, oh man.  
I know for sure no one knows otherwise we wouldn't be here, but maybe someone has a guess, opinion, idea, always bring it on, thanks

Out of all the antidepressants I tried years back, the ssri were the worst, because they have the same action as accutane.  Accutane is 13 cis retinoic acid. 

Real Vitamin A is a dht promoter. Google search vitamin A raypeat dht. Accutane is a small component of vitamin A. 

On 6/23/2020 at 1:16 PM, IhateAccutane said:

Do you have sometime the same pain after ejaculation, a little pain like a pin or needle. Right in the lower abdominal area, inside.

*it is not me in the photo

Clipboard02.jpg

I've experienced pain below the belly button several times, but it's never been in relation to anything sexual. 

On 6/27/2020 at 11:44 AM, Lio98 said:

Has anyone found a way to increase dihydrotestosterone? Got it checked last week and it's in the basement. So mean if someone has found something that has really increased its value, not just a guess what might help, I have tried a lot.

And nobody really knows if Accutane is also serotonin reuptake inhibiting??

Glycine boosts dht. But glycine also stimulates dopamine release, which is an issue for me atleast. I know from personal experience that accutane acts similar to ssri drugs. 

On 6/29/2020 at 8:24 AM, isojim said:

anybody want try dr pezzi method? 

using finasteride to recover post accutane syndrome.

I would never take propecia for any reason. That is absolutely horrible advice from Dr pezzi. Please don't do that to yourself. The solution to issues from evil things like accutane and propecia is not another evil thing. It's something natural that comes from God. 

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716
(@thomas76)

Posted : 07/05/2020 12:56 pm

On 6/29/2020 at 12:25 PM, isojim said:

i have zero libido and ED right now

it depends onhow you use it. i am say taking finasteride just a couple of days and then stop cold turkey. but i dont know about dosage.

you didnt get ED from accutane so we are not in a same position i think.

i dont know why this topic lasts more than 700 pages and onlyfew people tested finasteride. we have nothing worsethan no libido unless death.

i will use finastride soon and if it doesnt work try Ella. it is risky i know.

How can you say he didn't get Ed from accutane? I did, and so have lots of other accutane guys. It's ignorant to say otherwise. There is something worse than no libido. It's called Ed. I'd strongly advise against propecia. It will only make your issues worse. If I were to go the drug route I'd go with something like Viagra or cialis. But I'm not a big believer in pharmaceuticals.

On 6/30/2020 at 6:35 PM, isojim said:

anybody experience temporal hair loss on accutane? it is important ifyou experienced it. me? yes

I've experienced long term hair loss from accutane. Not real bad, but noticeable. I believe it's a circulation issue caused by accutane.

On 7/2/2020 at 7:00 AM, isojim said:

agree. we are not 100%same but everybody should find specific cure that fit the situation.

i fix my sexual dysfunction by marijuana temporary. marijuana is 5 alpha reductase inhibitor and proves finasteridd hypothesisfor curing post accutane syndrome. nobody know about longterm situation.

Whole Marijuana is not a dht inhibitor. The isolate Thc is a dht inhibitor. There are many other components of whole marijuana that may oppose thc. Marijuana is a relaxant. Marijuanas relaxant, anti stress effect temporarily restored your libido.

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716
(@thomas76)

Posted : 07/05/2020 1:12 pm

On 7/2/2020 at 6:19 PM, SaffronAide said:

Do you think that ''fried'' receptors are tissue fixated or is it about the whole endocrine system? I took Accutane for few days when i was just turned out 16. And since that day im concerned about if it did damage my height and facial development or not. Any chance anyone?

Jesus. I don't but what is interesting is that, when i got worse with many androgenic supplements two years ago. I had a pressure feeling on this area for a few days! Then it is gone and my baseline got lowered a bit more.

Accutane causes the bone growth plates to close. I've never read of any ways to reopen bone growth plates. 

On 7/4/2020 at 3:34 AM, Anna Nim said:

You took Accutane for a few DAYS and you are worried about damage to your height? and facial development? Unlikely, also if that is all you theoretically have concerns over, I'd be thrilled if I was you. Now, if you later took Propecia or Finn, then it seems to only get worse. I think the more people take the worse it is. It matters not what the damage is, as in a way there is no way to fix it. :(

I've read plenty of reports of ppl who took accutane or propecia for less than a week and it caused them permanent damage. It doesn't take long for these highly toxic poisons to take their effect. You're right about higher doses causing more damage. I believe the damage is fixable. 

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716
(@thomas76)

Posted : 07/05/2020 1:55 pm

Truejustice has said several very interesting and intelligent things lately. One being that accutane causes major circulatory issues, and that poor circulation is a primary effect of accutane. And that it's not necessarily permanent brain damage per se. I wholeheartedly agree with that. Tj also talks about needing to work with someone. I partially agree with that. I don't think it's a need to work with someone. I think it's a need to work with someTHING. For me, that thing is a quantum biofeedback machine. Amazon is where I got mine.

From day one, systemic hypertension is something the machine has picked up on. The machine creates very long lists of food and supplement recommendations, ranked from most to least helpful. When I zero in on the pituitary and hypothalamus, which is considered the cpu of the human body, I get ginkgo at the very top of the supplement recommendations section. When I look at the foods section, which is extremely long, garlic and beets are two of the foods that continually show up toward the top of the list.

There are tons of ginkgo brands out there, but only two that are any good. Those two brands are paradise herbs and Swanson health. Why are these two the only decent brands? Because they are the only two that utilize wholesome, full spectrum ginkgo. Everyone else uses garbage, fractionated extracts. And I absolutely notice the difference. When I use the garbage extract, it causes dopamine loss. When I use the full spectrum ginkgo, there is no dopamine loss. full spectrum ginkgo feels tons better to my brain than standardized extract ginkgo.

It's impossible to want to eat the same foods every day so I'm also supplementing with Oregon's wild garlic and doublewood beetroot, in addition to the paradise herbs ginkgo. I'm taking these three things in full daily dosage before work every day. Also doing omnivore diet, with non GMO and organic whenever possible. Orac rich Simply smoothie orchard berry is a staple food.

So far no drastic changes physically but massive improvement mentally. Fight or flight is something I've dealt with ever since accutane, and although this trio hasn't done much physically yet, it has completely eliminated the fight or flight feeling. If that's all this supplement trio ever does, for me that alone is worth it to continue with it. But I believe that the body tends to follow what's happening with the brain, and that physical changes should start to manifest if I continue with this trio daily. I'll keep the board posted as I go. Godspeed.

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397
(@calcified)

Posted : 07/05/2020 7:38 pm

Ever consider that it effects certain blood types differently? Blood types differ with clotting, maybe it's involved in wound healing and circulation? Thoughts?

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716
(@thomas76)

Posted : 07/05/2020 7:47 pm

That's an excellent theory cal. Not sure what my blood type is, but maybe everyone who knows their blood type should post up and see if there's a correlation.

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