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Can accutane stunt dick growth during puberty? I took it when I was 16.5 years old but I only took 10mg per day (very low dose luckily) for ~5 months. Are androgen production and receptors and Growth hormones affected significant enough to have an effect on penile growth at such a low dose? I dont remember any penile growth after my treatment so I don't know if this is from accutane or if I was done growing naturally around that time. (Literature suggests that penile growth doesnt stop before age 20 so I am a bit concerned about this..)
As far as I know there are no reports of stunted puberty/penile growth so I tend to think it doesnt have an effect on penile growth..
21 hours ago, Colinboko said:Got myself a medrol pack....
here we go folks...
Did you get your hormones tested, like a 24 hr salivary test or urinary? Any time you take that stuff you are suppressing your natural production, and would have to wean off carefully if not suitable, so unless you really need it, I'd be careful.
6 hours ago, mikez said:Did you get your hormones tested, like a 24 hr salivary test or urinary? Any time you take that stuff you are suppressing your natural production, and would have to wean off carefully if not suitable, so unless you really need it, I'd be careful.
all hormones were normal. no salivary or urinary cortisol but I did a blood one!
Im just trying it to test out the immunosuppression theory.
its a medrol pack for 5 days cause I said I had migraines (which isnt a lie) so it shouldnt suppress my hormones to a crazy extent.
For anyone who is interested - Rxisk and the PFS foundation have handed in a Citizens Petition to the FDA and MHRA.
This highlight why it is so important to report your side effects.
Please remember to donate to the Rxisk prize - they want to find a cure!!
If you have trouble accessing the petitions PM me.
On 5/1/2018 at 10:52 PM, TrueJustice said:Yep, thats a good way of putting it!!love the help we get from Roche, so much integrity from this company, really have the patients best interest at heart.
If you believe you have an autoimmune disease like MS look up Terry Wahls on youtube.
She has recovered from MS after being in a wheelchair for 5 years - she can now cycle 20+ miles.
It's a very hard protocol beyond most people.
Apparently you can cure diabetes if you can survive on 400 calories for 6 months!
An almost imposible task.
Rxisk are trying to do what Roche should be doing - can you all PLEASE DONATE?
On 5/11/2018 at 6:06 PM, Colinboko said:Got myself a medrol pack....
here we go folks...
Good luck! Very interested to see how you get on.
Have you considered DHEA as well?
Haidut on the Ray Pete forum suggests it. Don't quote me on this as I would have to go thorugh
my records for verification but I am sure that this is what he suggests for the PFS guys.
On 5/13/2018 at 7:24 AM, Colinboko said:all hormones were normal. no salivary or urinary cortisol but I did a blood one!Im just trying it to test out the immunosuppression theory.
its a medrol pack for 5 days cause I said I had migraines (which isnt a lie) so it shouldnt suppress my hormones to a crazy extent.
That's true for 5 days, but what happens if it works? Do you stay on it forever? Also keep note a lot of hormones 'poop out'... that is , initial response, then nothing. This is due to natural down regulation and negative feedback loops.
I experimented with low dose Hydrocortisone a while back, as a GP thought I had low morning cortisol, and supplements weren't doing much. I noticed a significant change in libido, fat loss, appetite increase, etc but after about 10 days, lost the response. I tried it again a year later, and a year after that, and wasn't able to even get 1 day of response.
1 hour ago, mikez said:That's true for 5 days, but what happens if it works? Do you stay on it forever? Also keep note a lot of hormones 'poop out'... that is , initial response, then nothing. This is due to natural down regulation and negative feedback loops.
I experimented with low dose Hydrocortisone a while back, as a GP thought I had low morning cortisol, and supplements weren't doing much. I noticed a significant change in libido, fat loss, appetite increase, etc but after about 10 days, lost the response. I tried it again a year later, and a year after that, and wasn't able to even get 1 day of response.
Hydrocortisone is quite a bit different in my opinion. Not nearly as potent. I have excess plasma proteins. Im trying this as an immunsupressor versus a hormone.
because I have
proteinuria
and I had an abnormal spike on my electrophoresis. (It wasnt multiple myeloma thank god but I never had protein in my urine before and it seems to only get worse)
my total blood protein seems to be getting higher and higher
and my ESR was low which is indicative of hyperviscosity
5 hours ago, Colinboko said:Hydrocortisone is quite a bit different in my opinion. Not nearly as potent. I have excess plasma proteins. I™m trying this as an immunsupressor versus a hormone.because I have
proteinuria
and I had an abnormal spike on my electrophoresis. (It wasn™t multiple myeloma thank god but I never had protein in my urine before and it seems to only get worse)
my total blood protein seems to be getting higher and higher
and my ESR was low which is indicative of hyperviscosity
Oh good point, yes HC is quite weak true. And I see where you are coming from. You aren't trying to correct what you feel is low cortisol, but rather inflammation. I hope all goes well..keep us updated 
28 minutes ago, mikez said:Oh good point, yes HC is quite weak true. And I see where you are coming from. You aren't trying to correct what you feel is low cortisol, but rather inflammation. I hope all goes well..keep us updated
Yes exactly! Sorry for the confusion! I will !
https://link.springer.com/article/10.1007%2Fs12020-018-1593-5
https://content.iospress.com/articles/international-journal-of-risk-and-safety-in-medicine/jrs745
What about a petition for accutane?
Does anybody feel that they can contribute?
Once again I highlight how important it is to report your side effects.
Ultimately getting recognition will lead to research for cures.
On 5/13/2018 at 2:03 AM, hatetane said:For anyone who is interested - Rxisk and the PFS foundation have handed in a Citizens Petition to the FDA and MHRA.
This highlight why it is so important to report your side effects.
Please remember to donate to the Rxisk prize - they want to find a cure!!Rxisk are trying to do what Roche should be doing - can you all PLEASE DONATE?
I have donated to RxISK and also recommend people donate to them. They are one of the only organisations who have bothered to take any notice of post accutane syndrome.
It may be worth contacting charitable funds who may be willing to donate to RxISK as well. I wanted to contact the pineapple fund which is a bitcoin based fund which donated huge amounts of money to all manner of charities including alternative charities like MAPS (psychedelic research) but the fund had stopped accepting applications.
IF THIS CONDITION BOTHERS YOU OR HAS AFFECTED YOUR LIFE, THEN YOU SHOULD DONATE. DONATING IS LIKELY TO BE A FAR MORE PRODUCTIVE USE OF TIME/RESOURCES THAN POSTING RANDOM STUFF ONLINE. WE NEED TO SUPPORT ANY ORGANISATIONS WHO ARE WILLING TO HELP AS WE ARE MOSTLY ON OUR OWN - https://rxisk.org/prize/
Haven't posted on here for a couple years, but still have ED. Came across this interesting info about advil and accutane and suicidal thoughts.
Suicidal thoughts is found among people who take Advil, especially for people who are female, 20-29 old , have been taking the drug for < 1 month, also take medication Accutane, and have Acne.
Here's a link
https://www.ehealthme.com/ds/advil/suicidal-thoughts/
It was weird, cause I was just looking up advil side effects, then Bam there's Accutane.
Hello people,
[removed]
Something caught my interest earlier. I have seen numerous PAS people report high DHEA levels. I was looking at the neurosteroid study of PFS patients. Interestingly, DHEA was one of the hormones which was found to be high in PFS people along withtestosterone, 5-alpha-androstane-3alpha and 17-beta-diol in the CSF.
It could be a coincidence but its possible there is a connection. It would be very informative to have a study of PAS patients which looked at the levels of neurosteroids as in the PFS study. This would provide us with strong evidence as to whether PAS is or isn't related to PFS and 5 alpha reductase activity. I wonder how much it would cost to have a person like professor Melcangi conduct the same kind of study on PAS patients. - https://www.sciencedirect.com/science/article/pii/S0960076017301024
If such a study was every completed and the results provided strong evidence to suggest PAS is indeed linked to PFS and 5 alpha reductase, it would provide a great motivation for PAS and PFS communities to combine resources/donations to find a treatment or pressure for more research to be conducted to provide greater evidence for these conditions and wider acceptance in the medical community. It is only after PAS has been acknowledged as a syndrome/condition that research into treatments/cures can be justified.
On 5/16/2018 at 10:07 PM, flynn said:Hello people,
[removed]
Something caught my interest earlier. I have seen numerous PAS people report high DHEA levels. I was looking at the neurosteroid study of PFS patients. Interestingly, DHEA was one of the hormones which was found to be high in PFS people along withtestosterone, 5-alpha-androstane-3alpha and 17-beta-diol in the CSF.
It could be a coincidence but its possible there is a connection. It would be very informative to have a study of PAS patients which looked at the levels of neurosteroids as in the PFS study. This would provide us with strong evidence as to whether PAS is or isn't related to PFS and 5 alpha reductase activity. I wonder how much it would cost to have a person like professor Melcangi conduct the same kind of study on PAS patients. - https://www.sciencedirect.com/science/article/pii/S0960076017301024
If such a study was every completed and the results provided strong evidence to suggest PAS is indeed linked to PFS and 5 alpha reductase, it would provide a great motivation for PAS and PFS communities to combine resources/donations to find a treatment or pressure for more research to be conducted to provide greater evidence for these conditions and wider acceptance in the medical community. It is only after PAS has been acknowledged as a syndrome/condition that research into treatments/cures can be justified.
I had high DHEA !
85-690 and mine is 757
my FSH was also high
1.6-8.0 and mine was 9.5
1 minute ago, TrueJustice said:How are you responding thus far?hopefully you get a good result from this
Havent started yet! Think Im going to start tomorrow!
Wanting to make sure there is nothing happening (went out the other night drinking and got pretty drunk) that could possibly skew my results. Want to be back at home in case things go south or something.
https://link.springer.com/article/10.1007%2Fs12020-018-1593-5
https://content.iospress.com/articles/international-journal-of-risk-and-safety-in-medicine/jrs745
What about a petition for accutane?
Does anybody feel that they can contribute?
Once again I highlight how important it is to report your side effects.
Ultimately getting recognition will lead to research for cures. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704911/
Bremner
first day almost done
so far have 16mg of prednisone floating around in my system and dont feel anything too drastic yet. Two more pills before bed. Definitely less achey and weirdly more clear. Nothing to writehome about.. gonna try and finish this out though even if nothing happens.
12 hours ago, hatetane said:https://link.springer.com/article/10.1007%2Fs12020-018-1593-5https://content.iospress.com/articles/international-journal-of-risk-and-safety-in-medicine/jrs745
What about a petition for accutane?
Does anybody feel that they can contribute?Once again I highlight how important it is to report your side effects.
Ultimately getting recognition will lead to research for cures. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704911/
Bremner
What area did you think theyll likely focus on??
Gut, Brain, Liver, Thyroid....I could go on.
If were to believe some posts over the years there have already been cures, everything from liver flushes to iodine therapy.
Either these people are bullshitting or they fluked it.
Having said that, your point about reporting sides is bang on, if nothing else hopefully it leads to a banning of these super dangerous drugs - thats a good thing for everybody!!
18 hours ago, TrueJustice said:What area did you think theyll likely focus on??Gut, Brain, Liver, Thyroid....I could go on.
If were to believe some posts over the years there have already been cures, everything from liver flushes to iodine therapy.
Either these people are bullshitting or they fluked it.
Having said that, your point about reporting sides is bang on, if nothing else hopefully it leads to a banning of these super dangerous drugs - thats a good thing for everybody!!
Recovery is one thing - maybe some people did recover but I know we are all slightly skeptical about this.
A cure would be a protocol that works for all. The PFS foundation are trying to do this and so are Rxisk.
This is Why Rxisk ask everyone to provide their case history and to list the things they tried and the things that helped even is it was just in the shot term. The reason for this is that if experience researchers have this data
it might hint at areas to research and give clues etc.
Once again I ask you all to report your side effects.
I have asked before and I ask again - please send be your case histories:
The email should include consent to share with regulators. Age, sex, dosage,duration. The prescribing experience(what warnings etc) and how and when the side effects became apparent etc.List all side effects and how the drug impacted your lives. Also state if you ever reported your sides and if not why not - this is an important factor!
I suspect you must all have you case histories already written - you must have shared already on this forum for instance.
I don't mind if it is a quick copy and paste if you really cant be asked to write a thorough email - at this stage anything would do. Without you guys reporting and without these case histories I simply have nothing to fight with so please do this for all PAS victims past, present and future.
You should all have my email by now - if not PM me.
TARGET - 100 case histories!
Thank you all
On 28/01/2017 at 7:39 PM, helpmeoutbuddies11 said:I had bad stomach problems after accutane. Strictly follow a leaky gut diet for a while. Drink homemade kefir, kombucha tea. Take a high quality bone broth and collagen powder everyday. Stop eating tons of sugar and junk. No dairy unless it's milk kefir or raw milk. Take HCL and a good digestive enzyme with cooked meals especially after 7:30 p.m. and etc. My problems were waaaay bad. Now my stomach is all fixed up. Zero problems with stomach or digestion now. Let me know if you have any questions.
hey man, what kind of stomach issues did you have? I think I'm experiencing something similar
Ok
fir the people who are trying Lions Mane
Lions Mane = 5AR downregulator
Cordyceps = 5AR upregulator (it also stops the breakdown of dopamine)
Cordy gives me good energy, no more yawning throughout the day.
sometimes a bit irritated
2 hours ago, TrueJustice said:Does that mean youve dropped taking lions mane??
No need to be taking it, theres no benefit?
I am experimenting right now. Does the low suppresion from Lions Mane cause a positive rebound on the whole system, or has it to be a mix of both worlds. Interesting stuff