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Hi, I have took Accutane too before and was fortunate to not to have the side effect as bad as you get it.
You are right that it does really give side effect as you described it. My heart goes with you and I knew how difficult it is to deal with side effects after you have to struggle with acne then now the side effects of the medication comes to add on the suffers of acne.
Just want to know, now what about your acne ? Is it gone or improved ?
18 minutes ago, Iden said:Hi, I have took Accutane too before and was fortunate to not to have the side effect as bad as you get it.
You are right that it does really give side effect as you described it. My heart goes with you and I knew how difficult it is to deal with side effects after you have to struggle with acne then now the side effects of the medication comes to add on the suffers of acne.
Just want to know, now what about your acne ? Is it gone or improved ?
Had mild acne still have mild acne nothing changed other than permanent sides from tan.
19 hours ago, guitarman01 said:It wouldnt be smart to rule anything out until it can be ruled out. I have a appointment tomorrow, I'll ask about the mre liver scan I mentioned. Its suppose to be more accurate and done in a actual hospital setting would hold more merit.
The traveling fibroscan service that you mentioned over there sounds similar to the life line screening here, and its a little controversial. Testing also depends on the skill of the operator.
Looking at this though, liver health has been thought of since day one by virtually everyone with all these post drug diseases and CFS. They have done and looked at everything to try to treat liver health.
The difference here would be some actual proof.
but maybe the liver is being affected just like everything else is being affected and eventually time might catch up.
Arent some of the Propecia guys on top of this liver scan idea? anyone had it? minus older individuals with cfs.This is severe liver disease, but it definitely affects the brain. I would love to rule this out with this scan^ if possible, trust me.
People have contemplated this for years.The neurology of liver failure
https://academic.oup.com/qjmed/article/96/9/623/1522594/The-neurology-of-liver-failure
That there is a relationship between the brain and the liver has been known for many years,1and patients with chronic liver disease frequently experience neurological problems. The commonest and most widely recognized is the reversible syndrome of hepatic encephalopathy
Overt hepatic encephalopathy is generally taken to refer to a syndrome of neuropsychiatric, neuropsychological and neurological disturbances that may arise as a complication of liver disease
Have you looked into a HIDA scan? This should identify issues with bile flow (cholestasis). Having one in a couple of weeks, so it'll be interesting to see if this comes back with anything (but expect the usual, 'nothing wrong'). I have constant pain under my right rib, and have intermittently had issues with eating fatty foods, yet liver enzymes and ultrasounds always come back clear.
On 9/27/2017 at 7:27 PM, mariovitali said:I believe that a Fibroscan test will prove otherwise, especially to people having this condition for more than 5 years.
Did you have a fibroscan yourself Mario, or had you resolved the issues before finding out about these? Specifically what condition do you think it was with your liver, cholestasis?
No i haven't , the only reason being that i recently got a new job in a foreign country and there are no good Fibroscan operators here apparently. So i am waiting to go back to Greece and have one.
The pain on the right side you mention (especially when you eat fatty food) is not a good sign in my opinion. However these are speculations so the best thing you can do is to have a Fibroscan. We have 6 out of 7 so far with Liver Fibrosis Stages 1-3.
I never came across the test you mentioned but definitely sounds interesting so i am looking forward to the results. I only had a Total Bile Acids test which was markedly elevated suggesting mild cholestasis. I will also have to have this test again.
Guys, have you ever checked your Albumin Levels? Has anyone of you found them to be low?
http://www.natural-acne-treatments.com/accutane-side-effects.html
Lets just say derms are in complete denial mode of the devastating long term side effects of this chemotherapy agent . I say wake the fuck up we are living in 2017 NOT 1017.
This is before they even knew of matrix gla protein functions in the body or their purpose. So even ten years after the release of accutane, they still had no idea about this.This is more of what I already posted.
When you see increased MGP mRNA levels minus additional k2, I believe this actually means deplete or increase the need for k dependant proteins. This is true with other studies. I believe what this could be doing is increasingundercarboxylated matrix gla protein (cardiovascular risk factor) that requires additional k2 to carboxylate.
For example,
Reduced bone density in patients on long-term warfarin
warfarin consistently stimulated cell proliferation (twofold). In osteoblast cultures, MGP mRNA levels were generally increased (three to tenfold).
Retinoic acid induces matrix Gla protein gene expression in human cells.
Abstract
The objective of this study was to investigate the possible regulation of the vitamin K-dependent matrix Gla (gamma-carboxyglutamic acid) protein (MGP) by retinoic acid, a regulation suggested by the recent observation that the human MGP promoter has a perfect direct repeat which is nearly identical to the retinoic acid-responsive element in the retinoic acid receptor-beta gene. We report that retinoic acid strongly increases MGP mRNA levels in all human cells tested, including osteoblasts, articular cartilage chondrocytes, and fibroblasts. In osteoblastic cells, MGP mRNA levels are increased by 25-fold at 1 microM retinoic acid and achieve half-maximal levels at 0.1 microM hormone. MGP is a small secreted protein of unknown function that is synthesized in a wide variety of vertebrate tissues. The present results suggest that part of the known actions of retinoic acid on skin, bone, cartilage, and other tissues in the human may be mediated by the stimulation of MGP synthesis and the consequent effect of increased MGP secretion on nearby target cells.
^not sure if this stays true over a period of time. But all of whats going on here might increase need ofvitamin k, mainly k2 in the long run.
Im still taking k2, not sure I would fully recommend it yet. If you look around the internet its a very polarizing supplement and some have had adverse reactions.
There is alot of information to support k2 though. But I guess we could do that with just about anything we want if we try hard enough.
On 9/28/2017 at 3:54 PM, tanedout said:I have constant pain under my right rib, and have intermittently had issues with eating fatty foods, yet liver enzymes and ultrasounds always come back clear.
I too have had brief inflammation issues regarding my upper right quadrant (liver area) back when I used to drink alcohol. I attribute it too drinking too much (obviously) and my slow regeneration lack of healing ability post Accutane. It was seemingly on the verge of a fatty liver issue as the symptoms were spot on with what I was feeling. Since I stopped drinking, improved my diet, and incorporated certain supplements I have not had pain since. I can even get away with drinking now and then (which would immediately bring me back to square one) without any issues as long as I remember to take two things after a night out.
1. I take a digestive enzyme daily to help me process food (VeganZyme or OmegaZyme). They work amazingly. A healthy pancreas produces millions of these enzymes and so taking one or two daily with a meal is just fine.
2. I take Silymarin and Glutathione the day after drinking. This reduces free radical damage and ameliorates inflammation. It actually works. No more pain.
8 hours ago, hatetane said:
Good video tane, thanks.
15 hours ago, hatetane said:
Thanks for the info with this.
Does anyone want to hazard a guess on what goes wrong in the process here with tane victims??
We've all tried Sam e, phenylalanine, tyrosine etc as stand alone supplement with little to no effect yeah??
My guess is the liver is altered with us and important processes that should happen don't, so it isn't a case of just taking these supplements but more to do with finding out why our livers don't function correctly!?
Either that or, take dopamine supplements but at the same time target the liver with a strong support such as Tudca and nothing less. Nothing is stronger correct when it comes to supporting liver?
I also could be completely wrong, all I know is the science in video makes perfect sense in the normal world but after tane we ain't dealing with normal anymore.....
On 10/1/2017 at 4:38 PM, TrueJustice said:I'm just fed up with having a dry leathery face and decided to Google "restoring"or "fixing" sebaceous glands and found this:
[Edited link out]
I read through the post. But there is nothing new. No solutions. To be honest, I don't think, that there is a possible cure for dry skin issues after accuntane. It is the core mechanism of isotretionin, to induce programmatic cell death in sebaceous gland cells.
6 minutes ago, Roland1968 said:I read through the post. But there is nothing new. No solutions. To be honest, I don't think, that there is a possible cure for dry skin issues after accuntane. It is the core mechanism of isotretionin, to induce programmatic cell death in sebaceous gland cells.
I know, I posted before reading through the whole thing - thought it might've offered up something good, unfortunately nothing really there other than frustrated victims looking for answers....
It kinda finishes up abruptly too, like everyone got pissed off that dermatologists couldn't resolve anything.
It does talk of topical ideas but that's never been a solution for damaged sebaceous glands has it, I mean who doesn't moisturise after tane?
18 minutes ago, TrueJustice said:I know, I posted before reading through the whole thing - thought it might've offered up something good, unfortunately nothing really there other than frustrated victims looking for answers....It kinda finishes up abruptly too, like everyone got pissed off that dermatologists couldn't resolve anything.
It does talk of topical ideas but that's never been a solution for damaged sebaceous glands has it, I mean who doesn't moisturise after tane?
Topical treatment can help against the effects of damged sebaceous gland but it does not revert the damage itself.
1 hour ago, Gladiatoro said:My favourite poster on here was accustained whatever happened to him. A perfect name. We truly are all accustained I refer to it as accudrained.
Yes, the user names "accustained" and "accutainted" were inspiration to my own name. Clever! In regards to what happened to "accustained," it appears his account has been deactivated. If you Google his screen name you will find a post that says it was edited by him, but the user name of the post is a generic "User511605" with the heading Inactive. That's too bad.
It sucks that many people come and go to these boards without a clear resolution. Some people certainly make strides and I believe great progress can be made, but I am skeptical of anything being touted as a cure. With most diseases--whether we're talking about diabetes, asthma, addiction, depression, or arthritis--symptom management is the goal. Should PFS or post-chemo syndrome whatever be different? Well, I wish. But in the meantime while research is conducted, I do not think symptom management is a bad goal! It gives you a realistic starting point. That approach has helped my cognitive and mental side effects better than anything else. Being "holistic" in my approach (i.e., being unwaveringly strict about my diet and workout regimen) has NOT helped me, and instead added unnecessary burden. To be clear, I still eat many whole foods and workout, but this idea of living perfectly healthy has not proven to pay off in any significant way. I wish it did. Wouldn't that make a great narrative though? "I got back to the basics. Became one with nature. And now I am cured!" The hippie in me wishes, lol.
On the Facebook group I run, a few people have claimed recovery, but there's an element of self-promotion behind it: "Purchase a consultation with me and we will discuss how your ying and yang are unbalanced and get you back to health." Or "Come follow my blog on my journey to better health." I just hope people stay skeptical.
In regards to Dr. Pezzi's method, I don't get any shilling vibes from him, but didn't he admit that he developed additional problems from the Finasteride?! That would give me hesitation. Does it not bother anyone else?
At this point, I still think the best approach is to type your symptoms into Pub Med and look at what is used to address your specific symptoms. My mental symptoms match the negative symptoms of schizophrenia and I happen to be helped by treatments for those issues (Sarcosine, NAC, etc.). I am no longer falling for hype, appeals to nature, appeals to abstract concepts that sound nice, and I am no longer trying any experimental medications.
I hate to sound like a religious right wing nutjob, but woth all of the mental and sexual issues, combined with our inability to even figure out what is wrong, combined with the fact that everytime people do nofap they seem to actually get better over time, I keep feeling like there is some diety punishing us for sexual stuff from the past/ masturbating/ PMO.
Look, I'm somewhat agnostic, and Definitely misotheist, but I'm gonna try nofap for as long as possible. Looking back, I actually felt better for a period on accutane when I didn't PMO. Like, I felt better than before Accutane for about a month.
Anyway, if there is some kind of god out there, then please god, go die in a hole now. We hate you!
3 hours ago, ACCUiTy_drANE said:Yes, the user names "accustained" and "accutainted" were inspiration to my own name. Clever! In regards to what happened to "accustained," it appears his account has been deactivated. If you Google his screen name you will find a post that says it was edited by him, but the user name of the post is a generic "User511605" with the heading Inactive. That's too bad.It sucks that many people come and go to these boards without a clear resolution. Some people certainly make strides and I believe great progress can be made, but I am skeptical of anything being touted as a cure. With most diseases--whether we're talking about diabetes, asthma, addiction, depression, or arthritis--symptom management is the goal. Should PFS or post-chemo syndrome whatever be different? Well, I wish. But in the meantime while research is conducted, I do not think symptom management is a bad goal! It gives you a realistic starting point. That approach has helped my cognitive and mental side effects better than anything else. Being "holistic" in my approach (i.e., being unwaveringly strict about my diet and workout regimen) has NOT helped me, and instead added unnecessary burden. To be clear, I still eat many whole foods and workout, but this idea of living perfectly healthy has not proven to pay off in any significant way. I wish it did. Wouldn't that make a great narrative though? "I got back to the basics. Became one with nature. And now I am cured!" The hippie in me wishes, lol.
On the Facebook group I run, a few people have claimed recovery, but there's an element of self-promotion behind it: "Purchase a consultation with me and we will discuss how your ying and yang are unbalanced and get you back to health." Or "Come follow my blog on my journey to better health." I just hope people stay skeptical.
In regards to Dr. Pezzi's method, I don't get any shilling vibes from him, but didn't he admit that he developed additional problems from the Finasteride?! That would give me hesitation. Does it not bother anyone else?
At this point, I still think the best approach is to type your symptoms into Pub Med and look at what is used to address your specific symptoms. My mental symptoms match the negative symptoms of schizophrenia and I happen to be helped by treatments for those issues (Sarcosine, NAC, etc.). I am no longer falling for hype, appeals to nature, appeals to abstract concepts that sound nice, and I am no longer trying any experimental medications.
I can't even get to "symptom" management cause absolutely nothing works!!!.......NOTHING!!!
The best I can hope for in terms of having a better day is getting a better nights sleep on 1 or 2 nights during the week.
Other than that I'm out of my mind with fatigue and brain fog, literally out of my mind.....
38 minutes ago, TrueJustice said:I can't even get to "symptom" management cause absolutely nothing works!!!.......NOTHING!!!The best I can hope for in terms of having a better day is getting a better nights sleep on 1 or 2 nights during the week.
Other than that I'm out of my mind with fatigue and brain fog, literally out of my mind.....
You need to test more....
If you have visible issues, doctors can't deny treatment.
Well, there will be more tests, I get the full thyroid results next week.
Im not feeling reassured or very hopeful I hate to say, no one on forum is yet to find anything we can all latch on to. I guess we've got no choice but to continue testing.
Right now I'm at a point where it's like, just fucken find something please, crohns or anything - just something I can at least leverage and get to work on!!
Will you be taking a Fibroscan test by any chance?
Any honest derm will tell you long term side effects of this chemotherapy agent are joint pain and depression and thats if your lucky . But I would describe it as reduced brain function , MRIs prove it , its a fact .
It's heart breaking kids are put on this they truly have no idea of what they are getting into and the life long effects. Being chronically dehydrated is NOT healthy .