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Repairing the long-term damage from Accutane

 
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(@abi72)

Posted : 08/28/2016 12:57 am

12 hours ago, john86 said:
Thanks for creating that web site, by the way! It's a great idea, and I just joined it last night.

Perhaps this is a silly thought, but I wonder if there are any doctors or scientists that might be able to somehow lend support to our cause? I remember, for example, in the news there was one poor kid who commit suicide, and his father was a doctor who was adamant that Accutane caused it (though maybe I'm remembering the details wrong).

Also, has anyone by any chance had a genetic test (such as by 23 and me)? To restate the obvious, one of the questions that might be asked is why only some people develop such permanent side effects from isotretinoin, and perhaps there's some methylation or genetic anomaly that could be associated with it. Most undoubtedly escape unscathed, although whether their overall health or incidence of disease is impacted later on in life remains to be seen.

I joined too!

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(@john86)

Posted : 08/28/2016 1:08 am

On 8/27/2016 at 10:08 PM, Dubya_B said:

The father of Jesse Jones, who committed suicide due to Accutane side effects, made the Dying for Clear Skin documentary but he is not a doctor. Perhaps you are thinking of Dr. John Santmann from the PFSF, whose son committed suicide after taking dutasteride?

When I wrote that, I was actually thinking of a similar tragic case of the father of a man who was accused of killing the doctor who prescribed him Accutane. (His name is Hans Peterson if you google it). The reason is that his father is a medical doctor who spoke out quite publicly in the media, claiming that Accutane destroyed his son. In such a case, I wouldn't even begin to know if it would be appropriate to, say, contact such an individual and ask if he might have any possible interest in our cause, or at least if he had discovered any medical insights into the drug; I assume in this case if he felt like being involved , he already would be. But still...Aside from just this example, the point is that there must be scientists and doctors in a similar position to Dr. Santmann but having been impacted by Accutane instead of finasteride.

By the way, do you happen to know what this Dr. Santmann thinks of Accutane? Does he think Accutane might cause similar damage to Propecia?

On 8/27/2016 at 10:08 PM, Dubya_B said:

Unfortunately, 23andMe doesn't provide full genome analysis, they only provide information based on snps (common point mutations at certain locations) detected in a portion of deciphered human genes and match those snps to genotypes associated with certain diseases. Not impossible, but we would be hard-pressed to find the answer through their service and would need someone with knowhow to interpret the data collected from many many post-Acutane patients to even begin. Worth the ~$100 for the analysis IMO though.

And now they doubled the price....There's another test by a company called Genos, for example, that is far more comprehensive, though it's more expensive than 23andMe. I might end up getting the test by Genos myself.

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(@cnb30)

Posted : 08/28/2016 7:18 pm

Do you guys know of a fast way to die, and just cease to be here anymore? Perhaps a quick way in New York City? How reliable is death by subway? How easy is it to get roof access to a 20+ story high rise from which I could throw myself off of?Are there still any really bad neighborhoods where you could get killed by using racial slurs or waving around your wallet at night?

Perhaps I could go hang around Roche's midtown headquarters, raising hell till I'm 6 feet under, so that headlines are made, Roche's crimes are uncovered and no body will ever have their soul stolen from this death drug produced by Murder Incorporated.

Perhaps, if the blood thirsty psychopaths who make and sell the drug in the first place were required to actually disclose how the death pills damaged users, then the scientific community might actually be able to help us in ways simply suggesting fasting and supplements could never do.

What is the best way to go about raising hell in a Pharmaseutical company in order to cause a pain that will make those who run the damn place listen, since no amount of money will do the trick? How best do we change the Thoughtsof the murderers?

I wish they knew whatsuffering and slow crinkling and tickling of their brain as feelings die off felt like. Theyneed to watch their orbitofrontal cortex and personality keel over, and understand what they have done. We needto see their ownmedicine slowly eat away at their brain. And most importantly, The worldneedsto see every stupid worthlesscell bag who took this medicine and saw it as a positive experience shut up.Thosedrones are pathetic weak minded fools who were put under the great operation from Yvgeny Zamyatin's book, We, and are now only corporatemouthpieces.

who wantsto help? Thinkabout all those worthless parasites have taken from you. Think about the isotretinoin rushing through your body giving your brain itches which are the destruction of your own sentience. You can sit back like a worthless rock and say "c'est la vie" like a worthlesssheep, and just let the wolf slowly eat away at the rest of our stupid herd, or you can retaliate, and send a message to the murder wolf to back the fuck off. Is there anyone worth a damn left in this world, or shall murdercorp destroy more of us.

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(@truejustice)

Posted : 08/28/2016 11:37 pm

4 hours ago, cnb30 said:

Do you guys know of a fast way to die, and just cease to be here anymore? Perhaps a quick way in New York City? How reliable is death by subway? How easy is it to get roof access to a 20+ story high rise from which I could throw myself off of?Are there still any really bad neighborhoods where you could get killed by using racial slurs or waving around your wallet at night?

Perhaps I could go hang around Roche's midtown headquarters, raising hell till I'm 6 feet under, so that headlines are made, Roche's crimes are uncovered and no body will ever have their soul stolen from this death drug produced by Murder Incorporated.

Perhaps, if the blood thirsty psychopaths who make and sell the drug in the first place were required to actually disclose how the death pills damaged users, then the scientific community might actually be able to help us in ways simply suggesting fasting and supplements could never do.

What is the best way to go about raising hell in a Pharmaseutical company in order to cause a pain that will make those who run the damn place listen, since no amount of money will do the trick? How best do we make the lives of the murderers who will never forgive us either a) shorter, or b. a permanent living hell?

i need to see someone hurt. I need to see them suffer th slow crinkling and tickling of their brain as their feelings die off. I need to watch their orbitofrontal cortex and personality keel over, and then watch them keel over until their death. I want to see the medicine slowly eat away at their brain. And most importantly, The worldneedsto see every stupid worthlesscell bag who took this medicine and saw it as a positive experience DEAD!! Thosedrones are pathetic weak minded fools who were put under the great operation from Yvgeny Zamyatin's book, We, and are now only corporatemouthpieces.

who wantsto help? Thinkabout all those worthless parasites have taken from you. Think about the isotretinoin rushing through your body giving your brain itches which are the destruction of your own sentience. You can sit back like a worthless rock and say "c'est la vie" like a worthlesssheep, and just let the wolf slowly eat away at the rest of our stupid herd, or you can retaliate, and send a message to the murder wolf to back the fuck off. Is there anyone worth a damn left in this world, or shall murdercorp destroy more of us.

Na not interested in that crap - you'll only end up hurting the poor lady doing temp work or the janitor cleaning the toilet etc....

The creators of Accutane I'd suggest are long gone!

"Eye for an Eye and we'll all be blind", plus you'll still have all your problems at the end of it.

How many years post tane are you?

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(@cnb30)

Posted : 08/29/2016 12:03 am

1 hour ago, TrueJustice said:
Na not interested in that crap - you'll only end up hurting the poor lady doing temp work or the janitor cleaning the toilet etc....

The creators of Accutane I'd suggest are long gone!

"Eye for an Eye and we'll all be blind", plus you'll still have all your problems at the end of it.

How many years post tane are you?

A couple things: I am 3.5 months post tane.

2nd, I would maybe be a little less eager for revenge if Roche would actually apologize for what they have done, yet they won't even acknowledge that the problem exists, and continue to murder individuals. They pay off governments, lawyers, and the people who are supposed to be helping us to let them get away with murder. You can sue as much as you want, but these companies are incredibly shielded.
Furthermore, who gives a fuck about whoever invented the product, it's still on the market, meaning a LIVING individual is responsible. Also, since in this day and age, the law, and passive ways of fighting back are tilted against us, we must do all we can to simply level the playing field.

It would be nearly impossible to dismiss such cases, and would lead to the drug earning a reputation that would not only increase the fear of users (try telling me this is only because of a senators son after a few dozen deaths that make national headlines) but also fear of corporations to get their hands anywhere near the murder drug. Also, passive MLK behaviors would to little to appeal to anyone as our scars are not visible to the naked eye.

Lastly, this is NOT simply "an eye for an eye". This is an eye to save millions of other eyes which the monster has yet to rip out.

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(@dubya_b)

Posted : 08/29/2016 12:03 am

4 hours ago, cnb30 said:

Do you guys know of a fast way to die, and just cease to be here anymore? Perhaps a quick way in New York City? How reliable is death by subway? How easy is it to get roof access to a 20+ story high rise from which I could throw myself off of?Are there still any really bad neighborhoods where you could get killed by using racial slurs or waving around your wallet at night?

Perhaps I could go hang around Roche's midtown headquarters, raising hell till I'm 6 feet under, so that headlines are made, Roche's crimes are uncovered and no body will ever have their soul stolen from this death drug produced by Murder Incorporated.

Perhaps, if the blood thirsty psychopaths who make and sell the drug in the first place were required to actually disclose how the death pills damaged users, then the scientific community might actually be able to help us in ways simply suggesting fasting and supplements could never do.

What is the best way to go about raising hell in a Pharmaseutical company in order to cause a pain that will make those who run the damn place listen, since no amount of money will do the trick? How best do we make the lives of the murderers who will never forgive us either a) shorter, or b. a permanent living hell?

i need to see someone hurt. I need to see them suffer th slow crinkling and tickling of their brain as their feelings die off. I need to watch their orbitofrontal cortex and personality keel over, and then watch them keel over until their death. I want to see the medicine slowly eat away at their brain. And most importantly, The worldneedsto see every stupid worthlesscell bag who took this medicine and saw it as a positive experience DEAD!! Thosedrones are pathetic weak minded fools who were put under the great operation from Yvgeny Zamyatin's book, We, and are now only corporatemouthpieces.

who wantsto help? Thinkabout all those worthless parasites have taken from you. Think about the isotretinoin rushing through your body giving your brain itches which are the destruction of your own sentience. You can sit back like a worthless rock and say "c'est la vie" like a worthlesssheep, and just let the wolf slowly eat away at the rest of our stupid herd, or you can retaliate, and send a message to the murder wolf to back the fuck off. Is there anyone worth a damn left in this world, or shall murdercorp destroy more of us.

Not going to argue against the validity of your message, but do you realize that openly expressing these thoughts in a public forum might lead to federal cops banging on your door before you are prepared for a visit?

ps- One of the discoverers of Accutane's utility in treating acne actually has apologized for it and wrote the FDA concerning its dangers.

F. W. Yoder, Isotretinoin: A Word of Caution, JAMA: The Journal of the American Medical Association, vol. 249, no. 3, p. 350, Jan. 1983.

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(@whackutane)

Posted : 08/29/2016 12:07 am

3 minutes ago, cnb30 said:
A couple things: I am 3.5 months post tane.

2nd, I would maybe be a little less eager for revenge if Roche would actually apologize for what they have done, yet they won't even acknowledge that the problem exists, and continue to murder individuals. They pay off governments, lawyers, and the people who are supposed to be helping us to let them get away with murder. You can sue as much as you want, but these companies are incredibly shielded.
Furthermore, who gives a fuck about whoever invented the product, it's still on the market, meaning a LIVING individual is responsible. Also, since in this day and age, the law, and passive ways of fighting back are tilted against us, we must do all we can to simply level the playing field, you can protest civilly, but that would be bringing a knife to a machine gun fight.
Furthermore, how do you know it would be a janitor, or clerk who would suffer, that is completely arbitrary, and furthermore, what would matter most is the symbolic nature of any form of revenge. Murdercorps was attacked. The story would make news, and inspire those who commit suicide post tane to atleast die for our cause. Furthermore, it would be nearly impossible to dismiss such cases, and would lead to the drug earning a reputation that would not only increase the fear of users (try telling me this is only because of a senators son after a few dozen deaths that make national headlines) but also fear of corporations to get their hands anywhere near the murder drug. Also, passive MLK behaviors would to little to appeal to anyone as our scars are not visible to the naked eye.

Lastly, this is NOT simply "an eye for an eye". This is an eye to save millions of other eyes which the monster has yet to rip out.

Cooked! Fb live stream it then

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(@cnb30)

Posted : 08/29/2016 1:23 am

2 hours ago, Dubya_B said:
Not going to argue against the validity of your message, but do you realize that openly expressing these thoughts in a public forum might lead to federal cops banging on your door before you are prepared for a visit?

ps- One of the discoverers of Accutane's utility in treating acne actually has apologized for it and wrote the FDA concerning its dangers.

F. W. Yoder, Isotretinoin: A Word of Caution, JAMA: The Journal of the American Medical Association, vol. 249, no. 3, p. 350, Jan. 1983.

At this rate, I no longer care. But yeah, I agree with you 110%. PS, I'm glad to know someone who invented the drug actually did atleast something. But yeah, I've cooked off a touch so I might tone it down (yeah I looked back at what I wrote and I realize I'm getting disturbingly impulsive) The way your mind gets messed up on this stuff disturbs me, and I need my filter back. The old me would've been horrified to say 4/5 of what I just said, but the new me has come close to jumping off bridges, in front of trains, etc, that I realize at one time or another, I'll probably go nuts like this again. Hell, atleast Id be required to (finally) get my head checked if authorities show up. I miss feeling intense feelings, and having a working frontal cortex to keep me from getting in trouble. Hell I would have been afraid to use too many cuss words online, let alone whatever the hell just happened an hour ago.

P.S. does anyone here have any experience with dealing with disturbing impulses? Perhaps, contact with doctors, etc. I'm not doing that well, and it's really disturbing. I someone to show up, and keep me from going mad. I need a fucking functioning frontal cortex, before I die, or worse, fail out of college.

I used to be too afraid to tell even girls who openly flirted with me that I liked them, now I can pretty much casually wind up in the Very important file of NSA and FBI folders and with a knock on my door in the middle of the night, because I'm in a bad mood.

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(@dubya_b)

Posted : 08/29/2016 2:26 am

On 8/28/2016 at 2:08 PM, john86 said:

When I wrote that, I was actually thinking of a similar tragic case of the father of a man who was accused of killing the doctor who prescribed him Accutane. (His name is Hans Peterson if you google it). The reason is that his father is a medical doctor who spoke out quite publicly in the media, claiming that Accutane destroyed his son. In such a case, I wouldn't even begin to know if it would be appropriate to, say, contact such an individual and ask if he might have any possible interest in our cause, or at least if he had discovered any medical insights into the drug; I assume in this case if he felt like being involved , he already would be. But still...Aside from just this example, the point is that there must be scientists and doctors in a similar position to Dr. Santmann but having been impacted by Accutane instead of finasteride.

By the way, do you happen to know what this Dr. Santmann thinks of Accutane? Does he think Accutane might cause similar damage to Propecia?

Not sure why it would be inappropriate to contact any parents who want to help or speak out. I think most of them just let it go after so long to save their sanity. Fighting against a company like Roche and a complacent FDA and not getting anywhere wears a person down. The fact that around a dozen parents showed at the UK anti-Roacctaune protest a few years ago shows that they are still looking for opportunities to make a move though.

I'm certain Dr. Santmann is aware of our overlap in symptoms and the overlap in MOA of both drugs, but can't speak on his personal opinion. Dr, Santmann's hands are tied either way because his organization is receiving money from many people who don't understand or care about Accutane sufferers possibly having the same condition. Politics. Look at it from the viewpoint of a "post-Accutane Foundation" funding scientific studies and supporting medical and media outreach programs for ex-finasteride users without extremely solid evidence of a related syndrome.

"And now they doubled the price....There's another test by a company called Genos, for example, that is far more comprehensive, though it's more expensive than 23andMe. I might end up getting the test by Genos myself."

Nice.

[Edited link out]

Still not full genome sequencing but you are right about Genos being way more thorough than the 23andMe service provides.

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(@cnb30)

Posted : 08/29/2016 2:55 am

I just thought I might let everyone know I was just down in the subway watching all the trains go by, thinking about how easy it would be to jump. Hell, I sat on the edge of the platform dangling my legs over the tracks till some drunk on the other side flipped out...

Temporary and vulnerableSentience and the universe are possibly the cruelest things ever to come into being, I must admit. It's truly a shame that I had to be a sentient being. It's honestly so fucked up when you think about it. Like you are a bunch of chemicals, and cells that just come together, and BAM an ego is formed. It's trulydisturbing. This whole idea that every one of us are individuals who see the world, and process it through these little meat computers in our heads. It's so fucked up when you think of this concept that everythingin the universe is simply filtered through your own mind. Godamn, organisms should have never gotten this intelligent as to question their own existence... Fuck it, if you want to get down to the bottom of it all, why the hell do energy and matter have to exist in the same parallel universe?

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(@abi72)

Posted : 08/29/2016 3:02 am

1 hour ago, cnb30 said:
At this rate, I no longer care. But yeah, I agree with you 110%. PS, I'm glad to know someone who invented the drug actually did atleast something. But yeah, I've cooked off a touch so I might tone it down (yeah I looked back at what I wrote and I realize I'm getting disturbingly impulsive) The way your mind gets messed up on this stuff disturbs me, and I need my filter back. The old me would've been horrified to say 4/5 of what I just said, but the new me has come close to jumping off bridges, in front of trains, etc, that I realize at one time or another, I'll probably go nuts like this again. Hell, atleast Id be required to (finally) get my head checked if authorities show up. I miss feeling intense feelings, and having a working frontal cortex to keep me from getting in trouble. Hell I would have been afraid to use too many cuss words online, let alone whatever the hell just happened an hour ago.

P.S. does anyone here have any experience with dealing with disturbing impulses? Perhaps, contact with doctors, etc. I'm not doing that well, and it's really disturbing. I someone to show up, and keep me from going mad. I need a fucking functioning frontal cortex, before I die, or worse, fail out of college.

I used to be too afraid to tell even girls who openly flirted with me that I liked them, now I can pretty much casually wind up in the Very important file of NSA and FBI folders and with a knock on my door in the middle of the night, because I'm in a bad mood.

I get you completely and we all know for sure that others have felt the same. However, you are only 3.5 months post accutane and you got to give this more time. You got to realise that you are not some boy who is unhappy with his life so is contemplating suicide or revenge. This drug has messed with your head and is making you irrational, for the moment at least you have very little control over what is happening to you. Please speak to your parents and show them this forum before they end up facing dire consequences. They will get you the help you need to at least stay safe for the time being. If you look at the stories of accutane related suicides - you will find that they are mostly done in very irrational circumstances - in other words they are not thought out but actually done in moments of extreme crisis. This also applies to the acts of revenge that have been committed.
Could your parents bare to lose you? Please think of them and get help now.
I am sure the stress of starting college can not be helping - if you seek help now I am sure something can be worked out to help get you through this.
As for who is at fault - every doctor who refers you and every dermatologist who prescribes accutane. They are the ones that are dishing this
poison out to innocent kids. They are committing crimes on a daily basis and are not being held accountable - it is a crime against humanity and I for one hope that one day they will face criminal charges.

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(@pedroe)

Posted : 08/29/2016 3:03 am

On 8/23/2016 at 10:15 PM, ACCUiTy_drANE said:
As someone who has largely abstained from complaining about my side effects, I would just like to say many of the viewpoints reflected in your post could not be further from my personal perspective on this issue. Suffering from the disease of depression has little to do with believing you have it any worse than anyone else. It has to do with your thought patterns, yes, but that is a minor component. The disease of depression often has complex biological causes which include but are not limited to: inflammation, bloodflow disturbances to specific regions of the brain, neurotransmitter disturbances in specific parts of the brain but NOT in others (rendering drugs that broadly increase one specific kind of neurotransmitter, useless), microbiome alterations, hippocampal atrophy, circadian rhythm disturbances, etc. Depression has more in common with arthritis than it does a hundred bad days. You may have already known depression is a complex disease, but my point is that all of the aforementioned factors cannot simply be thought away. Depression goes beyond mindset issues, and realizing life isn't easy for everyone does not address any root causes.

Finally, note that Accutane directly impacts many of the systems implicated in depression, as I am sure many people here know. That is why I am bewildered by the rhetoric I am reading. The complaints you witness may be annoying, but callous platitudes aren't going to restore our hippocampal volume(s) either.
Yes, I saw research done on people who were previously alcoholics. After 20 or so years of sobriety, their frontal lobes looked significantly better than those with four years or less of sobriety. What discouraged me was how four years was considered a limited amount of time. But healthy living, alcohol avoidance, and minimization of inflammation is probably our best shot at recovery, if brain damage in that region is the primary issue. Alcohol does NOT give me a pleasant buzz post-Accutane, so I'll have no problem with the first part.

I have to say that the viewpoints you relate to my post are a reflection of your misunderstanding that lead you to misguide my post in order to answer something that i never said. I didn't intend to make any statements about depression or its causes; i was stating my position regarding what this forum should be. " Repairing the long-term damage from Accutane ", that is to say, the intention of the forum is to help people that are hoping to find solutions to their accutane related problems. Many have benefit from the shared information that can provide some approaches and directions to heal our damaged body. That being said, i can only reinforce that this is not the place to mourn and say that the situation is hopeless and suicide is the solution, hopefully you can understand that now.

Besides that, the shallowness of what you say about depression matches the pretentiousness of your statements. First of all, i never said anything about "thought patterns" and "mindset", i would never use those words whose theoretical basis rely on american behaviorist psychological points of view, due to its superficiality. Moreover, you inconsistently mention causes of depression without demonstrate them, like the majority of the articles that try to state organic causes for depression without dealing with the complexity of the issue. Yet, you assume that depression in accutane users is related to brain damage, maybe a reduction of the hippocampal volume, so what? What is the meaning of that? Does this mean that we are screwed and the best thing to do is find medicines/supplements that can induce neurogenesis? This is the same perspective that lead us to where we are.

By the way, depression is a complex disease, and you seem to ignore the subjective and phenomenological side of it, pointed only in a very superficial way as "though patterns" and "mindset". The way people experience this is much related to personal history and is also very related to the prejudicial life changes post accutane, in other words, your body changes make you feel like an old sick person that is incapable of performing activities that were a huge part of your life, sometimes the meaning of your life, like one guy here whose dream was to become an professional athlete, he was being successful, but after sometime taking tane couldnt play basketball anymore. This is fucking fucking depressive and really hard to deal, you need to re-signify your life, your identity, takes a lot of mourning, crying, talking and so much more to start to see a new horizon of possibilities, a psychotherapy can be very helpful. So, I recognize the importance of mourning and I strongly advise to cry, complain etc.., after all, you are dealing with many losses, you are suffering and need time to get your pieces back together, many are able to do so and, afterwards, stand up and fight against in a much better way, with more wisdom that greatly helps in the recovery process.

But again, although passing through a mourning process is important I dont think this is the place for it. People come here with hope, its our responsibility to show that we are not dealing with something easy, but saying that is hopeless is not only irresponsible, but heavily detrimental for all of us. I am not saying you said that, but we should all be careful and avoid statements that point to a hopeless end, because this is not true, may be for some, but not for many and hopefully not for the most that visit this forum.

By the way, psychotherapy provides brain changes as well, your brain is constantly changing in a bad or good manner and this comes not only with drugs or organic interventions. Note that you can see a lot of people (forums, articles) that got depressed, even suicidal, while on tane, but after a while got better with" life", by this i mean non-medical approaches, i.e, they did something for sure, but weren't worrying/hiding about/on their "brain damage". For sure their depression has a brain image correspondence, children that have suffered severe traumas during early childhood often become addicts/depressive/suicidal and there arealso brain patterns for those things, brain patterns that are used by organicist scientists to affirm depression as an purely organic issue. Our body and mind is complex and you should be bewildered with that, not trying to argue in such a poor manner, making assumptions and affirmations lacking consistent.

15 hours ago, cnb30 said:
At this rate, I no longer care. But yeah, I agree with you 110%. PS, I'm glad to know someone who invented the drug actually did atleast something. But yeah, I've cooked off a touch so I might tone it down (yeah I looked back at what I wrote and I realize I'm getting disturbingly impulsive) The way your mind gets messed up on this stuff disturbs me, and I need my filter back. The old me would've been horrified to say 4/5 of what I just said, but the new me has come close to jumping off bridges, in front of trains, etc, that I realize at one time or another, I'll probably go nuts like this again. Hell, atleast Id be required to (finally) get my head checked if authorities show up. I miss feeling intense feelings, and having a working frontal cortex to keep me from getting in trouble. Hell I would have been afraid to use too many cuss words online, let alone whatever the hell just happened an hour ago.

P.S. does anyone here have any experience with dealing with disturbing impulses? Perhaps, contact with doctors, etc. I'm not doing that well, and it's really disturbing. I someone to show up, and keep me from going mad. I need a fucking functioning frontal cortex, before I die, or worse, fail out of college.

I used to be too afraid to tell even girls who openly flirted with me that I liked them, now I can pretty much casually wind up in the Very important file of NSA and FBI folders and with a knock on my door in the middle of the night, because I'm in a bad mood.

In the end of the treatment i started to feel very anxious in a totally new way, i thought i would lose my mind. It's already 1 1/2 years later and i feel much better. I cried a lot, freaked out a lot. Eventually i started psychotherapy and to smoke pot due to some information i found on forums. In the beginning the intensity of my sadness and anxiety got worse, but that intensity lead me to get my pieces back together faster. I also believe pot has an antidepressant effect after sometime using it. Anyway oil consumption is far better than smoking.

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(@abi72)

Posted : 08/29/2016 3:17 am

Would anyone admit to compulsive behaviour whilst on accutane. One kid told be that he started stealing for no apparent reason and that it was actually freaking him out. Some would argue that shoplifting might just be a sign of depression but I believe it goes much deeper than that in relation to accutane.

It is in my opiniona side effect of this drug that should be recognised. So in addition to the hell on your health that accutane causes you may also end up with a criminal record through no fault of your own.

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(@cnb30)

Posted : 08/29/2016 3:19 am

5 minutes ago, hatetane said:

Would anyone admit to compulsive behaviour whilst on accutane. One kid told be that he started stealing for no apparent reason and that it was actually freaking him out. Some would argue that shoplifting might just be a sign of depression but I believe it goes much deeper than that in relation to accutane.

It is in my opiniona side effect of this drug that should be recognised. So in addition to the hell on your health that accutane causes you may also end up with a criminal record through no fault of your own.

Holy shit!! I started walking on train tracks 2 months into accutane!

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(@pedroe)

Posted : 08/29/2016 3:45 am

Some days ago i heard about a girl that used to be a friend, she always had psychological issues, but nothing extreme until recently. She had a psychotic outbreak 1 years post accutane, but while on it she started to be much more anxious than she already was. It's difficult to say that is the cause, but i guess it triggered or worsen problems she already had, i don't know. Anyway,Is really hard to understand the general effect of this drug, specially because the outcome differs a lot in each individual.

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(@abi72)

Posted : 08/29/2016 4:07 am

48 minutes ago, cnb30 said:
Holy shit!! I started walking on train tracks 2 months into accutane!

If only your dermatologist had alerted to this possible side effect - it is a possible marker that you should have been taken off accutane.

This is why we have to recognise and report every side effect!

Unreated but an interesting little video clip on sibo

http://www.beyondmthfr.com/mthfr-and-sibo/

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(@gladiatoro)

Posted : 08/29/2016 8:04 am

Our skin is a major organ and absorbs everything. Treat your skin naturally.
WHAT'S CONTAINED IN ONE SQUARE INCH OF SKIN
The complex structures of the skin contained within one square inch:
- 65 hairs
- 9,500,000 cells
- 95 to 100 sebaceous (oil) glands
- 19 yards (17 meters) of blood vessels
- 650 sweat glands
- 78 yards (70 meters) of nerves
- 78 sensory apparatuses for heat
- 19,500 sensory cells at the ends of nerve fibers
- 1,300 nerve endings to record pain
- 160 to 165 pressure apparatuses for the perception of tactile stimuli
- 13 sensory apparatuses for cold

(Adapted from Joel Gerson, Milady's Standard Textbook for Professional Estheticians, 8th edition)

ISOTRETINOIN $%^& over all these skin cell features , leaving the body in a constant sate of CHRONIC CELLUAR DEHYDRATION . And sadly chronic cellular dehydration prematurely KILLS.

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MemberMember
299
(@macleod)

Posted : 08/29/2016 9:53 am

Hey cnb30, your posts are straying from the thread topic and probably violating some form of the rules. For the sake of the thread being shut down, you should probably utilize a different forum, may i suggest (removed) We have 0 authority here and a lot of people rely on this thread.

Not saying we don't believe you, or feel your pain, but you are relatively new, so I also have to consider that you may be subversively trying to get this thread closed. So, to avoid that, let's just stick to thread topic which is Repairing the Long Term side effects of Isotretinoin.

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MemberMember
158
(@accuity_drane)

Posted : 08/29/2016 2:22 pm

13 hours ago, PedroE said:

I didn't intend to make any statements about depression or its causes; i was stating my position regarding what this forum should be. " Repairing the long-term damage from Accutane ", that is to say, the intention of the forum is to help people that are hoping to find solutions to their accutane related problems. Many have benefit from the shared information that can provide some approaches and directions to heal our damaged body. That being said, i can only reinforce that this is not the place to mourn and say that the situation is hopeless and suicide is the solution, hopefully you can understand that now. \

You didn't have to make any statements about what you believed to be the causes for depression. Your viewpoint could be clearly inferred by the manner in which you talked about it. In the original post you said: " Suicidal guys, please, give us a break, it's not easy for anyone." This clearly implies you see depression as a problem of perspective, or mindset. I never denied that whiny posts are annoying, but one has to be open-minded.

13 hours ago, PedroE said:

Besides that, the shallowness of what you say about depression matches the pretentiousness of your statements.

On 8/22/2016 at 0:49 PM, PedroE said:

i reached a point where i had inflammation everywhere in my body, my face was a mess, pain allover, after very depressing months and intense caring of myself i began to get better, specially mentally. But is not easy, It's fucking hard and we need inspiring stories of people that are fighting and making life progresses, even if they can't find a cure or an improvement yet. So, go mourn elsewhere.

Is telling suicidal people to mourn elsewhere (because you only want to hear inspiring stories) pretentious too? I am fine with accepting adjectives thrown my way, so long they are applied equally.

13 hours ago, PedroE said:

Moreover, you inconsistently mention causes of depression without demonstrate them

Yet, you assume that depression in accutane users is related to brain damage, maybe a reduction of the hippocampal volume, so what?

I don't assume anything. I broaden the discussion and look at multiple perspectives.And no, I do not think healing depression is a simple process. As I have eluded to in the past, depression affects MULTIPLE bodily systems.I do not believe any one compound will cure me. (Why am I always accused of looking at ONE system at a time when I CONSTANTLY talk about looking at the big picture?!?!?!) There are connections to inflammation, the gut, etc. So do not try to paint me as ignorant. That being said, I will now demonstrate three-four different ways Accutane can affect the brain:

http://www.ncbi.nlm.nih.gov/pubmed/15251924

We now show, in a mouse model, that endogenous RA generated by synthetic enzymes in the meninges acts on hippocampal granule neurons, and chronic (3-week) exposure to a clinical dose of 13-cis RA may result in hippocampal cell loss.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387382/

"This report demonstrates that a clinical dose (1 mg/kg/day) of 13-cis-RA in mice significantly reduces cell proliferation in the hippocampus and the subventricular zone, suppresses hippocampal neurogenesis, and severely disrupts capacity to learn a spatial radial maze task. The results demonstrate that the regions of the adult brain where cell proliferation is ongoing are highly sensitive to disruption by a clinical dose of 13-cis-RA."

https://www.ncbi.nlm.nih.gov/pubmed/20708044

"13-Cis-retinoic acid (13-cis-RA) causes depression-related behavior in mice. Hypothalamic dysregulation has been implicated in clinical depression. In fact, apoptosis of hypothalamic neurons may lead to depression after myocardial infarction. . . .We hypothesize that the ability of 13-cis-RA to decrease hypothalamic cell number may contribute to the increased depression-related behaviors observed in mice."

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276716/#R173

"In the case of patients reported to the Norwegian Medicines Agency, single photon emission computed tomography (SPECT) of the brain was performed in 15 cases who reported lasting neurological symptoms. Altered brain function was seen in all cases involving altered or reduced frontal lobe blood flow. Ten of these patients were evaluated to have organic brain damage."

13 hours ago, PedroE said:

But again, although passing through a mourning process is important I dont think this is the place for it. People come here with hope, its our responsibility to show that we are not dealing with something easy, but saying that is hopeless is not only irresponsible, but heavily detrimental for all of us. I am not saying you said that, but we should all be careful and avoid statements that point to a hopeless end, because this is not true, may be for some, but not for many and hopefully not for the most that visit this forum.

This is the problem. You call it mourning. Some people are genuinely suffering from a clinical DISEASE called depression because of Accutane. It isn't part of a process or phase, for everyone. Some people are relatively healthy post-Accutane EXCEPT in their mental state (although more than the brain is likely affected). Again, I agree that hearing people whine and complain is annoying. In some ways, it is even discouraging. But we have to understand that there could be biological reasons for it. Callous rhetoric is not the answer. People are free to say what they want, you included! But that doesn't mean no one should be called out either.

13 hours ago, PedroE said:

By the way, psychotherapy provides brain changes as well, your brain is constantly changing in a bad or good manner and this comes not only with drugs or organic interventions.

I will end on a lighter note. I agree. I am happy to see some nuance. That is all.

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macleod, Dubya_B, macleod and 3 people reacted
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223
(@gladiatoro)

Posted : 08/29/2016 2:34 pm

The big question every one wants to know , does isotretinoin cause depression , answer NOT necessarily he / she will have to live with reduced brain function for the rest of his / her life FACT.

As as I have often stated derms LIE , MRI's DON'T.

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MemberMember
359
(@dubya_b)

Posted : 08/29/2016 2:50 pm

On 8/29/2016 at 8:53 PM, macleod said:

Hey cnb30, your posts are straying from the thread topic and probably violating some form of the rules. For the sake of the thread being shut down, you should probably utilize a different forum, may i suggest (removed) We have 0 authority here and a lot of people rely on this thread.

Not saying we don't believe you, or feel your pain, but you are relatively new, so I also have to consider that you may be subversively trying to get this thread closed. So, to avoid that, let's just stick to thread topic which is Repairing the Long Term side effects of Isotretinoin.

Na. Terroristic threats are pushing the envelope a bit much for the [removed] site and aren't welcome there either. It's a place to give hope to people who have lost hope in the general tone of this thread.

Macleod, why don't you join? The site as a whole might be geared toward promoting scientific research, but the Accutane forum is still a forum meant for all Accutane sufferers.

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ACCUiTy_drANE, macleod, ACCUiTy_drANE and 3 people reacted
MemberMember
45
(@cnb30)

Posted : 08/29/2016 3:05 pm

I still can't believe I went off like that yesterday. I feel like I need to be saved from my own brain.

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MemberMember
0
(@lozagon)

Posted : 08/29/2016 3:09 pm

For all of you who have dry skin even after stopping accutain (even years later) I will give you my 2 cents about what worked for me.
I used accutainfor 6 months. 17 years later my skin was very dry all the time, to the point that i was getting older much faster than i was supposed to since my skin produced no oil whatsoever. I also got eye dryness. Also my skin has been extremely sensitive to anything i put on it, (not even cetaphil moisturizer) because it leaves my skin red as if i was sick...the only thing i can put is zink to protect my skin and i spray vegetable glycerin in my skin. However what worked for me to kinda jump start some of my sebaceous glands i discovered by accident when i traveled to finland and got into a sauna. (187 degrees fahrenheit) I went for 3 days and 3 days later i started noticing my forehead being shiny aswell as my nose and chin. The rest of my face seem more hydrated and i actually got several acne break outs on my forehead. This is after not getting any acne for years. I said halleluya my freeking sebaceous glands are starting to work again. Ofcourse i do not wan't it to return to the way it was before accutain which was way too oily, but now my skin is not as dry. I guess if it gets dryer in the winter i can go to the sauna more often. by the way i am 44 years old and you can manage any new breakouts with lycopads 10% glycol acid from amazon which are very good at preventing new breakouts.

Hope this helps some of you who are desperate to get your oil back.

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0
(@Anonymous)

Posted : 08/29/2016 4:08 pm

What the actual F*CK. I had no idea any of this could be a potential side effect. F*CK. Not only is my face ruined but now my health too? Thanks to my old dermatologist. I could just find him and do something ill regret.

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MemberMember
6
(@pedroe)

Posted : 08/29/2016 5:01 pm

3 hours ago, ACCUiTy_drANE said:

You didn't have to make any statements about what you believed to be the causes for depression. Your viewpoint could be clearly inferred by the manner in which you talked about it. In the original post you said: " Suicidal guys, please, give us a break, it's not easy for anyone." This clearly implies you see depression as a problem of perspective, or mindset. I never denied that whiny posts are annoying, but one has to be open-minded.

I have already answered that, stating my point of view of what depression is, unfortunately you seem to insist in something that is logically unacceptable using mere rhetoric. Every text is open to multiple interpretation, to avoid that we study logic and analytical philosophy to make statements whose assumptions lead directly to one conclusion, this goes back to Aristotelian logic. By no means my sentence lead necessarily to the conclusion you reached.

What i said and meant was:Suicidal guys, give us a break, is not easy for anyone, everyone here is fighting, suffering and your fatal affirmations aren't helping anyone, quite the opposite, but if you insist doing so you clearly need to and i can understand that, but this is not the place. Taking into account that the objective of this forum is to repair the damage caused by accutane i guess fatalist perspectives aren't proper.

Once again you mention "perspective" and "mindset" as my point of view of what depression is, but this reductionism couldn't be further from my point of view. I feel sorry that you insist on something that i already refuted.

I don't disagree that accutane may cause brain damage that may lead to depression as a result of a biological change that has little or nothing to do with subjective issues, i also read studies about that and got to know people in this situation, the point is all those studies fail to elucidate why it doesn't affect everyone, specially long term, they are fragmented gazes of a complex problem. As i said, many people get depressed during the treatment and even after, but get better after a while, so, their brain was affect but got better after a while? Why some are able to heal and others not? Besides that, mourning may have little effect, or be even useless, for some, but vital for many, specially those whose suffering is much more related to the body debilitating side effects, i am sure you heard stories about people that weren't depressed until they found theirselves living in an old and sick body.

I believe accutane mess up with the way our body function and this may have many bad outcomes, but western medicine, Cartesian as it is, fails to appreciate the complex interconnected processes of our body, they keep working with fragmented pictures for the sake of a reductionist empiricism.

Anyway, i don't want tohold on a pointless argument, i won't be trying to make you understand my point of view.Hopefully we can understand each other.

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