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Accutane: Knees popping on only 40 MG??!! Hi, everyone. I'm new here. I'm 29 and taking accutane for the second time (first time when I was 18). I was on 20 mg for a month, now am on 40 mg for 2 weeks. My knees started popping tonight, an... | In forum Prescription acne medications | 20 years ago |