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| Resistance To Doxycycline And Minocycline - Will It Work Again? On 6/18/2014 at 1:11 AM, silverlight22 said: Guys, Had a question. I was on Doxycycline (200mg) for 6 months before I became resistant to it. I switched to Minocycline ... | In forum Prescription acne medications | 6 years ago |