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Washing Hydrogen Peroxide off after a while?

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I like to put little globs of the regimen hydrogen peroxide on active pimples as a spot treatment, but once it dries it gets kind of cakey which is an issue when I try to put moisturizer on. Do I lose any benefits if I rinse my face off after the hydrogen peroxide dries, or does it do most of its work pretty much immediately?

Edited by mt.hizzle
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